Biotechnological Aspects and Perspective of Microbial Keratinase Production.

abstract：:Background. Stenotrophomonas maltophilia bacteremia (SMB) is the most perilous situation as compared to other types of S. maltophilia infection. The present study aimed to investigate the clinical features, distribution, drug resistance, and predictors of survival of SMB in a tertiary-care hospital of China. Methods. ...

journal_title：BioMed research international

authors： Chen Y,Suo J,Du M,Chen L,Liu Y,Wang L,Liang Z

更新日期：2019-12-09 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; ...

journal_title：BioMed research international

authors： Mirsaeidi M,Farshidpour M,Allen MB,Ebrahimi G,Falkinham JO

更新日期：2014-01-01 00:00:00

abstract：:COVID-19 is a pandemic which has spread to more than 200 countries. Its high transmission rate makes it difficult to control. To date, no specific treatment has been found as a cure for the disease. Therefore, prediction of COVID-19 cases provides a useful insight to mitigate the disease. This study aims to model and ...

journal_title：BioMed research international

authors： Attanayake AMCH,Perera SSN

更新日期：2020-12-03 00:00:00

abstract：:Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In general, high leve...

journal_title：BioMed research international

authors： Song WH,Ballard JW,Yi YJ,Sutovsky P

更新日期：2014-01-01 00:00:00

abstract：:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...

journal_title：BioMed research international

authors： Wang P,Wang J,Ma J,Jin G,Guan X

更新日期：2017-01-01 00:00:00

abstract：:Dengue fever, a reemerging disease, is putting nearly 2.5 billion people at risk worldwide. The number of infections and the geographic extension of dengue fever infection have increased in the past decade. The disease is caused by the dengue virus, a flavivirus that uses mosquitos Aedes sp. as vectors. The disease ha...

journal_title：BioMed research international

authors： De La Guardia C,Lleonart R

更新日期：2014-01-01 00:00:00

abstract：:Feature selection has become the essential step in biomarker discovery from high-dimensional genomics data. It is recognized that different feature selection techniques may result in different set of biomarkers, that is, different groups of genes highly correlated to a given pathological condition, but few direct comp...

journal_title：BioMed research international

authors： Dessì N,Pascariello E,Pes B

更新日期：2013-01-01 00:00:00

abstract：:Resveratrol has recently been used as a supplemental treatment for several neurological and nonneurological diseases. It is not known whether resveratrol has neuroprotective effect on amyotrophic lateral sclerosis (ALS). To assess the effect of resveratrol on the disease, we tested this agent on an ALS model of SOD1(G...

journal_title：BioMed research international

authors： Song L,Chen L,Zhang X,Li J,Le W

更新日期：2014-01-01 00:00:00

abstract：:During vertebrate development, the lung inaugurates as an endodermal bud from the primitive foregut. Dichotomous subdivision of the bud results in arborizing airways that form the prospective gas exchanging chambers, where a thin blood-gas barrier (BGB) is established. In the mammalian lung, this proceeds through conv...

journal_title：BioMed research international

authors： Makanya A,Anagnostopoulou A,Djonov V

更新日期：2013-01-01 00:00:00

abstract：Materials and Methods:Various aqueous extracts were prepared from this plant and preadministered per os to albino mice 3 h before APAP administration, once daily for one week. Animals from the normal group were given only distilled water while those from negative control received only APAP 250 mg/kg. After treatment, m...

journal_title：BioMed research international

authors： Galani BRT,Owona BA,Chuisseu DPD,Machewere E,Ngantchouko CBN,Moundipa PF

更新日期：2020-08-31 00:00:00

abstract：:Long noncoding RNAs play an essential role in bladder cancer progression. The role of long noncoding RNA EGFR-AS1 in bladder cancer needs further study. We used clinical specimens to analyze the relationship between EGFR-AS1 and bladder cancer patients' characteristics. The functional experiments and mechanism studies...

journal_title：BioMed research international

authors： Wang A,Jiang A,Gan X,Wang Z,Huang J,Dong K,Liu B,Wang L,Chen M

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

journal_title：BioMed research international

authors： Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

更新日期：2016-01-01 00:00:00

abstract：:Significant positive effects, particularly on psychological state in patients who completed the follow-up pulmonary rehabilitation programs, are indicated by a large number of studies. Yet, a remarkable proportion of selected patients drop out from these programs. In this study, we investigated existing differences on...

journal_title：BioMed research international

authors： Tselebis A,Kosmas E,Bratis D,Pachi A,Ilias I,Harikiopoulou M,Theodorakopoulou E,Velentzas K,Dumitru S,Moussas G,Siafakas N,Tzanakis N

更新日期：2014-01-01 00:00:00

abstract：:Mycobacterium avium subsp. paratuberculosis (Map) is the causative agent of a chronic intestinal inflammation in ruminants named Johne's disease or paratuberculosis and a possible etiopathological agent of human Crohn's disease (CD). Analysis of macrophage transcriptomes in response to Map infection is expected to pro...

journal_title：BioMed research international

authors： Abendaño N,Juste RA,Alonso-Hearn M

更新日期：2013-01-01 00:00:00

abstract：:Cardiogenic shock (CS) is uncommon in patients suffering from acute myocardial infarction (AMI). Long-term outcome and adverse predictors for outcomes in AMI patients with CS receiving percutaneous coronary interventions (PCI) are unclear. A total of 482 AMI patients who received PCI were collected, including 53 CS an...

journal_title：BioMed research international

authors： Lin MJ,Chen CY,Lin HD,Wu HP

更新日期：2017-01-01 00:00:00

abstract：:[This retracts the article DOI: 10.1155/2015/108458.]. ...

journal_title：BioMed research international

authors： International BR

更新日期：2017-01-01 00:00:00

abstract：:Chosen aspects of examinations of inorganic gunshot particles by means of scanning electron microscopy and energy dispersive X-ray spectrometry technique are presented. The research methodology of particles was worked out, which included a precise and repeatable procedure of the automatic detection and identification ...

journal_title：BioMed research international

authors： Brożek-Mucha Z

更新日期：2014-01-01 00:00:00

abstract：:Despite significant advances in the study of the molecular mechanisms altered in the development and progression of neurodegenerative diseases (NDs), the etiology is still enigmatic and the distinctions between diseases are not always entirely clear. We present an efficient computational method based on protein-protei...

journal_title：BioMed research international

authors： Nguyen TP,Caberlotto L,Morine MJ,Priami C

更新日期：2014-01-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：:Kawasaki disease (KD) is an acute systemic vasculitis of childhood with prolonged fever, and the diagnosis of KD is mainly based on clinical criteria, which is prone to misdiagnosis with other febrile infectious (FI) diseases. Currently, there remain no effective molecular markers for KD diagnosis. In this study, we a...

journal_title：BioMed research international

authors： Zhong J,Huang Q,Wang Y,Gao H,Jia H,Fan J,Liang H

更新日期：2020-04-26 00:00:00

abstract：:Anterior cruciate ligament injuries are common in humans, though cellular components of the knee have little regenerative or proliferation potential. This study investigated the differentiation of human amnion-derived mesenchymal stem cells (hAMSCs) into human anterior cruciate ligament fibroblasts (hACLFs) in vitro t...

journal_title：BioMed research international

authors： Li Y,Liu Z,Jin Y,Zhu X,Wang S,Yang J,Ren Y,Fu Q,Xiong H,Zou G,Liu Y

更新日期：2017-01-01 00:00:00

abstract：Background:Sympathetic sprouting in the dorsal root ganglion (DRG) following nerve injuries had been proved to induce adult neuropathic pain. However, it is unclear whether the abnormal sprouting occurs in infant nerve injury. Methods:L5 spinal nerve ligation (SNL) or sham surgery was performed on adult rats and 10-da...

journal_title：BioMed research international

authors： Liu P,Zhang Q,Gao YS,Huang YG,Gao J,Zhang CQ

更新日期：2020-06-16 00:00:00

abstract：:The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...

journal_title：BioMed research international

authors： Martínez-Torteya A,Treviño V,Tamez-Peña JG

更新日期：2015-01-01 00:00:00

abstract：Aims:To evaluate the effectiveness and safety of peritoneal dialysis (PD) in treating refractory congestive heart failure (RCHF) with cardiorenal syndrome (CRS). Methods:A total of 36 patients with RCHF were divided into type 2 CRS group (group A) and non-type 2 CRS group (group B) according to the patients' clinical ...

journal_title：BioMed research international

authors： Shao Q,Xia Y,Zhao M,Liu J,Zhang Q,Jin B,Xie J,Xu B,Gong R,Jiang C

更新日期：2018-05-17 00:00:00

abstract：INTRODUCTION:Spectroscopic analysis of urine samples from laboratory animals can be used to predict the efficacy and side effects of drugs. This employs methods combining (1)H NMR spectroscopy with quantification of biomarkers or with multivariate data analysis. The most critical steps in data evaluation are analytical...

journal_title：BioMed research international

authors： Schreier C,Kremer W,Huber F,Neumann S,Pagel P,Lienemann K,Pestel S

更新日期：2013-01-01 00:00:00

abstract：:Taking into account that there are controversial antioxidative effects of inhalational anesthetics isoflurane and sevoflurane and absence of comparison of genotoxicity of both anesthetics in animal model, the aim of this study was to compare DNA damage and antioxidant status in Wistar rats exposed to a single time to ...

journal_title：BioMed research international

authors： Rocha TL,Dias-Junior CA,Possomato-Vieira JS,Gonçalves-Rizzi VH,Nogueira FR,de Souza KM,Braz LG,Braz MG

更新日期：2015-01-01 00:00:00

abstract：:Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...

journal_title：BioMed research international

authors： Farini A,Sitzia C,Erratico S,Meregalli M,Torrente Y

更新日期：2014-01-01 00:00:00

abstract：Objective:The NOCTURNIN gene links nutrient absorption and metabolism to the circadian clock. Shift workers are at a heightened risk of overweight and of developing obesity and metabolic syndrome. This study investigates the diurnal variation of NOCTURNIN in healthy volunteers and its expression levels in rotational sh...

journal_title：BioMed research international

authors： Bracci M,Copertaro A,Ciarapica V,Barbaresi M,Esposito S,Albanesi A,Valentino M,Ledda C,Rapisarda V,Santarelli L

更新日期：2019-07-31 00:00:00

abstract：:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic ind...

journal_title：BioMed research international

authors： Deev RV,Drobyshev AY,Bozo IY,Isaev AA

更新日期：2015-01-01 00:00:00

abstract：:Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

journal_title：BioMed research international

authors： Xu C,Zhang H

更新日期：2015-01-01 00:00:00