EGFR-AS1 Promotes Bladder Cancer Progression by Upregulating EGFR.

abstract：:The aim of the present study was to determine if the Ki-67 labelling index reflects invasiveness of pituitary adenoma and to evaluate IL-17A concentration in blood serum of pituitary adenoma patients. The study was conducted in the Hospital of Lithuanian University of Health Sciences. All pituitary adenomas were analy...

journal_title：BioMed research international

authors： Glebauskiene B,Liutkeviciene R,Vilkeviciute A,Gudinaviciene I,Rocyte A,Simonaviciute D,Mazetyte R,Kriauciuniene L,Zaliuniene D

更新日期：2018-05-31 00:00:00

abstract：:Finding an optimal set of discriminative features is still a crucial but challenging task in biomedical science. The complexity of the task is intensified when any of the two scenarios arise: a highly dimensioned dataset and a small sample-sized dataset. The first scenario poses a big challenge to existing machine lea...

journal_title：BioMed research international

authors： Segera D,Mbuthia M,Nyete A

更新日期：2020-08-17 00:00:00

abstract：:The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image for quantifying the...

journal_title：BioMed research international

authors： Zheng X,Wei W,Huang Q,Song S,Wan J,Huang G

更新日期：2017-01-01 00:00:00

abstract：:The purpose of this study is to evaluate the therapeutic effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) activated by curcumin (CUR) on PC12 cells induced by 1-methyl-4-phenylpyridinium ion (MPP+), a cell model of Parkinson's disease (PD). The supernatant of hUC-MSC and hUC-MSC activated by 5 ...

journal_title：BioMed research international

authors： Jinfeng L,Yunliang W,Xinshan L,Yutong W,Shanshan W,Peng X,Xiaopeng Y,Zhixiu X,Qingshan L,Honglei Y,Xia C,Hongwei W,Bingzhen C

更新日期：2016-01-01 00:00:00

abstract：Background:Circular RNA (circRNA) is a noncoding RNA that forms a closed-loop structure, and its abnormal expression may cause disease. We aimed to find potential network for circRNA-related competitive endogenous RNA (ceRNA) in atrial fibrillation (AF). Methods:The circRNA, miRNA, and mRNA expression profiles in the ...

journal_title：BioMed research international

authors： Liu T,Zhang G,Wang Y,Rao M,Zhang Y,Guo A,Wang M

更新日期：2020-09-29 00:00:00

abstract：:Tripartite Motif Containing 11 (TRIM11), an E3 ubiquitin ligase, is identified as a carcinogen causing certain human cancers. However, the specific role of TRIM11 is still uncovered in human osteosarcoma (OS) cells. To explore the role of TRIM11 in OS cells, TRIM11 was induced by silencing and overexpression in OS cel...

journal_title：BioMed research international

authors： Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

更新日期：2019-12-25 00:00:00

abstract：:How to decrease intraoperative bleeding, shorten surgical time, and increase safety in spinal surgery is an important issue. Ultrasonic bone removers and FloSeal have been proven to increase safety, reduce the surgical duration, and decrease intraoperative bleeding in skull base surgery. Therefore, we aimed to compare...

journal_title：BioMed research international

authors： Chen HT,Hsu CC,Lu ML,Chen SH,Chen JM,Wu RW

更新日期：2019-05-19 00:00:00

abstract：:Exclusive enteral nutrition (EEN) has been proven to be effective and safe in treating pediatric Crohn's disease (CD). EEN induces pediatric CD remission possibly through three pathways: (1) direct anti-inflammatory effects, (2) improved epithelial barrier function, and (3) modulation of the gut microbiota. Recent stu...

journal_title：BioMed research international

authors： Gong D,Yu X,Wang L,Kong L,Gong X,Dong Q

更新日期：2017-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/6935123.]. ...

journal_title：BioMed research international

authors： Pruimboom L,Ruiz-Núñez B,Raison CL,Muskiet FAJ,Freese J

更新日期：2017-01-01 00:00:00

abstract：:The current developments of the new biological drugs targeting interleukin 5 (IL-5) and IL-5 receptor allowed to expand the treatment options for severe hypereosinophilic asthma. Clinicians will then be able to choose between antibodies targeting either circulating IL-5 or its receptor expressed on eosinophils and bas...

journal_title：BioMed research international

authors： Bagnasco D,Caminati M,Ferrando M,Aloè T,Testino E,Canonica GW,Passalacqua G

更新日期：2018-11-05 00:00:00

abstract：Objective:Neuroimaging studies revealed the functional reorganization or the structural changes during stroke recovery. However, previous studies did not combine the functional and structural information and the results might be affected by heterogeneous lesion. This study aimed to investigate functional activation-inf...

journal_title：BioMed research international

authors： Wu Z,Cheng L,Yang GY,Tong S,Sun J,Miao F

更新日期：2017-01-01 00:00:00

abstract：:A new fungus Cladosporium oxysporum GQ-3 producing extracellular xylanase was isolated from decaying agricultural waste and identified based on the morphology and comparison of internal transcribed spacer (ITS) rDNA gene sequence. C. oxysporum produced maximum xylanase activity of 55.92 U/mL with wheat bran as a subst...

journal_title：BioMed research international

authors： Guan GQ,Zhao PX,Zhao J,Wang MJ,Huo SH,Cui FJ,Jiang JX

更新日期：2016-01-01 00:00:00

abstract：:Resveratrol has recently been used as a supplemental treatment for several neurological and nonneurological diseases. It is not known whether resveratrol has neuroprotective effect on amyotrophic lateral sclerosis (ALS). To assess the effect of resveratrol on the disease, we tested this agent on an ALS model of SOD1(G...

journal_title：BioMed research international

authors： Song L,Chen L,Zhang X,Li J,Le W

更新日期：2014-01-01 00:00:00

abstract：:Sudden cardiac death is the main cause of mortality in patients affected by chronic heart failure (CHF) and with history of myocardial infarction. No study yet investigated the intra-QT phase spectral coherence as a possible tool in stratifying the arrhythmic susceptibility in patients at risk of sudden cardiac death ...

journal_title：BioMed research international

authors： Piccirillo G,Moscucci F,Persi A,Di Barba D,Pappadà MA,Rossi P,Quaglione R,Nguyen BL,Barillà F,Casenghi M,Magrì D

更新日期：2014-01-01 00:00:00

abstract：:To evaluate the effects of curcumin (CUR) on tumor progression and angiogenesis in cervical cancer- (CaSki-) implanted nude mice and on the angiogenic biomarkers: vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), and epidermal growth factor receptor (EGFR). CaSki cells were subcutaneously injected i...

journal_title：BioMed research international

authors： Yoysungnoen-Chintana P,Bhattarakosol P,Patumraj S

更新日期：2014-01-01 00:00:00

abstract：:This study aimed to analyse the diversity of the Campylobacter jejuni population in broilers and to evaluate the major source of contamination in poultry meat. Eight rearing cycles over one year provided samples from three different broiler farms processed at the same slaughterhouse. A total of 707 C. jejuni were isol...

journal_title：BioMed research international

authors： Marotta F,Garofolo G,Di Donato G,Aprea G,Platone I,Cianciavicchia S,Alessiani A,Di Giannatale E

更新日期：2015-01-01 00:00:00

abstract：Background:In patients with reduced systolic function, the natriuretic peptide system affects heart failure (HF) progression, but the expression of key activating (corin) and degrading enzymes (neprilysin) is not well understood. Methods and Results:This pilot study (n=48) compared plasma levels of corin, neprilysin, ...

journal_title：BioMed research international

authors： Zaidi SS,Ward RD,Ramanathan K,Yu X,Gladysheva IP,Reed GL

更新日期：2018-07-26 00:00:00

abstract：:Different batches of atorvastatin, represented by two immediate release formulation designs, were studied using a novel dynamic dissolution apparatus, simulating stomach and small intestine. A universal dissolution method was employed which simulated the physiology of human gastrointestinal tract, including the precis...

journal_title：BioMed research international

authors： Čulen M,Tuszyński PK,Polak S,Jachowicz R,Mendyk A,Dohnal J

更新日期：2015-01-01 00:00:00

abstract：:Iron deficiency anemia has been a widespread disease. As an effective and stable iron supplement, the physiochemical properties of the polysaccharide iron complex have been widely studied. In this study, we characterized a novel polysaccharide-iron(III) complex extracted in an edible fungal species Auricularia auricul...

journal_title：BioMed research international

authors： Liu T,Liu T,Liu H,Fan H,Chen B,Wang D,Zhang Y,Sun F

更新日期：2019-06-11 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...

journal_title：BioMed research international

authors： Zheng G,Han G,Soomro NQ,Ma L,Zhang F,Zhao Y,Zhao X,Zhou C

更新日期：2019-04-15 00:00:00

abstract：Methods:Patients with shoulder pain were recruited in an outpatient rehabilitation clinic at the Third Affiliated Hospital of Sun Yat-Sen University from January 1, 2017, to June 30, 2018. These shoulder pain patients with or without limitation in joint movement can be included in the study. All of them received muscul...

journal_title：BioMed research international

authors： Jiang L,He J,Chen CPC,Xie D,Mai Y,Yue B,Dou Z

更新日期：2020-08-25 00:00:00

abstract：:Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected. Objectives. The purpose of this study was to determine the magnitude of Leishmania sp. infection and potenti...

journal_title：BioMed research international

authors： Hoyos CL,Cajal SP,Juarez M,Marco JD,Alberti D'Amato AM,Cayo M,Torrejón I,Cimino RO,Diosque P,Krolewiecki AJ,Nasser JR,Gil JF

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:Using a swine model of acute myocardial ischemia, we sought to validate N-(11)C-methyl-dopamine ((11)C-MDA) as an agent capable of imaging cardiac sympathetic nerve injury. METHODS:Acute myocardial ischemia was surgically generated in Chinese minipigs. ECG and serum enzyme levels were used to detect the pres...

journal_title：BioMed research international

authors： Zhou W,Wang X,He Y,Nie Y,Zhang G,Wang C,Wang C,Wang X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to ...

journal_title：BioMed research international

authors： Kadioglu TC,Aliyev E,Celtik M

更新日期：2014-01-01 00:00:00

abstract：Background:Anion gap (AG) has been proved to be associated with prognosis of many cardiovascular diseases. This study is aimed at exploring the association of AG with inhospital all-cause mortality and adverse clinical outcomes in coronary care unit (CCU) patients. Method:All data of this study was extracted from Medi...

journal_title：BioMed research international

authors： Sun T,Cai C,Shen H,Yang J,Guo Q,Zhang J,Zhang B,Ding Y,Zhou Y

更新日期：2020-08-27 00:00:00

abstract：:The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5'-hydroxy auraptene (5'-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stimulator for osteobla...

journal_title：BioMed research international

authors： Abdallah BM,Ali EM,Elsawy H,Badr GM,Abdel-Moneim AM,Alzahrani AM

更新日期：2019-12-28 00:00:00

abstract：:The complete chloroplast genome of J. flava, an endangered medicinal plant in Saudi Arabia, was sequenced and compared with cp genome of three Acanthaceae species to characterize the cp genome, identify SSRs, and also detect variation among the cp genomes of the sampled Acanthaceae. NOVOPlasty was used to assemble the...

journal_title：BioMed research international

authors： Yaradua SS,Alzahrani DA,Albokhary EJ,Abba A,Bello A

更新日期：2019-08-06 00:00:00

abstract：:Myopia is the most common ocular abnormality. Its high and growing prevalence has contributed to a recent surge in surgical interest in the disorder, since retinal detachment in eyes with high myopia differs from that in emmetropic eyes or eyes with low myopia. The myopic eye, because of its specific anatomy, poses sp...

journal_title：BioMed research international

authors： Semeraro F,Morescalchi F,Russo A,Romano MR,Costagliola C

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To distinguish between normal (SV-HUC-1) and cancerous (TCCSUP) human urothelial cell lines using microelectrical impedance spectroscopy (μEIS). MATERIALS AND METHODS:Two types of μEIS devices were designed and used in combination to measure the impedance of SV-HUC-1 and TCCSUP cells flowing through the channe...

journal_title：BioMed research international

authors： Park Y,Kim HW,Yun J,Seo S,Park CJ,Lee JZ,Lee JH

更新日期：2016-01-01 00:00:00