Abstract:
:Bone grafts are medical devices that are in high demand in clinical practice for substitution of bone defects and recovery of atrophic bone regions. Based on the analysis of the modern groups of bone grafts, the particularities of their composition, the mechanisms of their biological effects, and their therapeutic indications, applicable classification was proposed that separates the bone substitutes into "ordinary" and "activated." The main differential criterion is the presence of biologically active components in the material that are standardized by qualitative and quantitative parameters: growth factors, cells, or gene constructions encoding growth factors. The pronounced osteoinductive and (or) osteogenic properties of activated osteoplastic materials allow drawing upon their efficacy in the substitution of large bone defects.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Deev RV,Drobyshev AY,Bozo IY,Isaev AAdoi
10.1155/2015/365050subject
Has Abstractpub_date
2015-01-01 00:00:00pages
365050eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
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