Abstract:
:Cancer related fatigue (CRF) is a common and debilitating symptom that can influence quality of life (QoL) in cancer patients. The increase in survival times stresses for a better understanding of how CRF affects patients' QoL. This was a cross-sectional descriptive study with 148 randomly recruited prostate cancer patients aiming to explore CRF and its impact on QoL. Assessments included the Cancer Fatigue Scale, EORTC QLQ-C30, and EORTC QLQ-PR25. Additionally, 15 in-depth structured interviews were performed. Quantitative data were analyzed with simple and multiple regression analysis and independent samples t-test. Qualitative data were analyzed with the use of thematic content analysis. The 66.9% of the patients experienced CRF with higher levels being recorded for the affective subscale. Statistically significant differences were found between the patients reporting CRF and lower levels of QoL (mean = 49.1) and those that did not report fatigue and had higher levels of QoL (mean = 72.1). The interviews emphasized CRF's profound impact on the patients' lives that was reflected on the following themes: "dependency on others," "loss of power over decision making," and "daily living disruption." Cancer related fatigue is a significant problem for patients with advanced prostate cancer and one that affects their QoL in various ways.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Charalambous A,Kouta Cdoi
10.1155/2016/3989286subject
Has Abstractpub_date
2016-01-01 00:00:00pages
3989286eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章abstract::Although cases of Mediterranean spotted fever (MSF) have been reported for decades in southeastern Romania, there are few published data. We retrospectively studied 339 patients, diagnosed with MSF at the National Institute of Infectious Diseases "Prof. Dr. Matei Bals" between 2000 and 2011, in order to raise awarenes...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/395806
更新日期:2013-01-01 00:00:00
abstract::Recently, an important topic of the acquired immunodeficiency syndrome (AIDS) had been published in 2013. In this report, the expression of the IFN-induced myxovirus resistance 2 (MX2) had been defined the function to kill the human immunodeficiency virus (HIV). The screening from the Traditional Chinese Medicine (TCM...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/871576
更新日期:2014-01-01 00:00:00
abstract:Objective:To analyze the ten-year surgical outcomes and postoperative complications of French-Door laminoplasty (FDL) in the management of multilevel cervical spondylotic myelopathy (MCSM) and analyze the prognostic factors for FDL in treating MCSM. Methods:64 patients with MCSM, who were operated by FDL, were include...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/3627071
更新日期:2020-05-06 00:00:00
abstract::The interplay between Aspergillus fumigatus and the host immune response in lung infection has been subject of studies over the last years due to its importance in immunocompromised patients. The multifactorial virulence factors of A. fumigatus are related to the fungus biological characteristics, for example, structu...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/693023
更新日期:2013-01-01 00:00:00
abstract::Background. Increased metal ion levels following total hip arthroplasty (THA) with metal-on-metal bearings are a highly debated topic. Local soft tissue reactions with chronic pain and systemic side effects such as neuropathy are described. The aim of the current study was to determine the serum metal ion concentratio...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3726029
更新日期:2017-01-01 00:00:00
abstract:Introduction:To investigate the clinical results of arthroscopic management for the unstable inferior leaf of the lateral meniscus anterior horn and associated cysts through an inframeniscal portal. Methods:From March 2005 to October 2014, 64 patients with an unstable inferior leaf of the lateral meniscus anterior hor...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9264907
更新日期:2017-01-01 00:00:00
abstract::Bacterial biofilms are communities of microorganisms attached to a surface. Biofilm formation is critical not only for environmental survival but also for successful infection. Helicobacter pylori is one of the most common causes of bacterial infection in humans. Some studies demonstrated that this microorganism has b...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/914791
更新日期:2015-01-01 00:00:00
abstract::Introduction and Objectives. Neutrophil-to-lymphocyte ratio (NLR) has been suggested to be a simple marker of the systemic inflammatory response in critical care patients. We previously assessed the utility of NLR as a biomarker to predict tumor recurrence and cancer death in bladder cancer patients who underwent radi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/9846823
更新日期:2016-01-01 00:00:00
abstract::The aim of this study is to inform about the development of a new semispherical surgical instrument for the bipolar multielectrode radiofrequency liver ablation. Present tools are universal; however they have several disadvantages such as ablation of healthy tissue, numerous needle punctures, and, therefore, longer op...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/532792
更新日期:2014-01-01 00:00:00
abstract:Background:The kaya business is known to pose significant health-related risks to female migrants. This study sought to explore the health-related concerns of female head porters in the Mallam Atta market, Accra, Ghana. Methods:A qualitative study was conducted in which twenty female head porters at the Mallam Atta ma...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6201837
更新日期:2018-02-13 00:00:00
abstract:Background:Adverse drug reactions (ADRs) are the known cause of morbidity and mortality, resulting in increased hospitalization, healthcare costs, complications, and decreased adherence in patients with depression. This study is aimed at evaluating adverse drug reactions due to antidepressants among patients with depre...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6682928
更新日期:2020-11-16 00:00:00
abstract::Coconut palm (Cocos nucifera) is an important commercial crop in many tropical countries, but its industry generates large amounts of residue. One way to address this problem is to use this residue, coconut husk, to produce second-generation (2G) ethanol. The aim of this review is to describe the methods that have bee...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/4916497
更新日期:2018-09-27 00:00:00
abstract::Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/480573
更新日期:2014-01-01 00:00:00
abstract::Chronic obesity is a known risk factor for metabolic syndrome. However, little is known about pathological changes in the small intestine associated with chronic obesity. This study investigated cellular and subcellular level changes in the small intestine of obese mice. In this study, a mouse model of obesity was est...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5251738
更新日期:2016-01-01 00:00:00
abstract:Purpose:To detect the responsiveness and predictive ability of the Chinese version Action Research Arm Test (C-ARAT) in participants within the first 3 months after cerebral infarction. Methods:Ninety-seven individuals (75 men, mean age 59.87 ± 10.94 years) with a first cerebral infarction were enrolled in this study....
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8270187
更新日期:2019-10-07 00:00:00
abstract::The immune system is regulated by distinct signaling pathways that control the development and function of the immune cells. Accumulating evidence suggest that ligation of aryl hydrocarbon receptor (Ahr), an environmentally responsive transcription factor, results in multiple cross talks that are capable of modulating...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/520763
更新日期:2014-01-01 00:00:00
abstract:Purpose:Coconut water has long been touted for its medicinal qualities including natural hydration. We sought to determine whether its consumption would induce changes to urinary lithogenic factors beyond changes in urine volume. Materials and Methods:After Institutional Review Board approval, volunteers with no prior...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3061742
更新日期:2018-11-01 00:00:00
abstract::The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feeds, but its effects on fish have not yet been investigated extensively. In order to fill this gap a feeding trial with juvenile carp was conducted. Three groups of fish were fed feeds contaminated with ZEN at three concentrations (low: 332 μg kg(-1...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/420702
更新日期:2015-01-01 00:00:00
abstract::In this paper, differences between multichannel EEG signals of artists and nonartists were analyzed during visual perception and mental imagery of some paintings and at resting condition using approximate entropy (ApEn). It was found that ApEn is significantly higher for artists during the visual perception and the me...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/764382
更新日期:2014-01-01 00:00:00
abstract::Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/6293163
更新日期:2016-01-01 00:00:00
abstract::Nematodes infections are responsible for debilitating conditions and economic losses in domestic animals as well as livestock and are considered an important public health problem due to the high prevalence in humans. The nematode resistance for drugs has been reported for livestock, highlighting the importance for de...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/879263
更新日期:2015-01-01 00:00:00
abstract::One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/319589
更新日期:2015-01-01 00:00:00
abstract::Contrast-induced nephropathy (CIN) is now one of the three leading causes of acute kidney injury in the world. A lot is known about the risk factors of CIN, yet it remains a major cause of morbidity, end stage renal disease, prolonged hospital stay, and increased costs as well as a high mortality. Many patients underg...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/423848
更新日期:2014-01-01 00:00:00
abstract::Spinal cord injured (SCI) individuals show an altered hemodynamic response to metaboreflex activation due to a reduced capacity to vasoconstrict the venous and arterial vessels below the level of the lesion. Exercise training was found to enhance circulating catecholamines and to improve cardiac preload and venous ton...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/893468
更新日期:2014-01-01 00:00:00
abstract::Introduction. In the field of orthopaedic surgery, the use of osteogenic material in larger defects is essential. Autograft and allograft are both known methods, and autograft is believed to be the best choice. But autograft is associated with additional invasive procedures which can prove difficult in fragile patient...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9358989
更新日期:2020-03-03 00:00:00
abstract:Background:Methadone Maintenance Treatment (MMT) program's success depends on the likelihood of reducing drop-out rate and keeping patients remaining in the program. There have been neither comprehensive studies about variation among patients who have been experiencing MMT for long period nor prediction of MMT period i...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9081968
更新日期:2018-08-07 00:00:00
abstract:OBJECTIVE:Data about endocrine and bone disease in nontransfusion-dependent thalassaemia (NTDT) is scanty. The aim of our study was to evaluate these complications in β-TI adult patients. METHODS:We studied retrospectively 70 β-TI patients with mean followup of 20 years. Data recorded included age, gender, haemoglobin...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/174581
更新日期:2014-01-01 00:00:00
abstract::Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5184595
更新日期:2016-01-01 00:00:00
abstract::Objectives. Osteopontin (OPN) is overexpressed in breast cancers, while its clinical and prognostic significance remained unclear. This study aimed to assess the prognostic value of OPN, especially its splice variants, in breast cancers. Methods. Data were extracted from eligible studies concerning the OPN and OPN-c e...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2016/7310694
更新日期:2016-01-01 00:00:00
abstract::Cisplatin is an antitumor drug used in the treatment of a wide variety of malignancies. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern. To help understand mechanisms involved in the development of kidney injury, cisplatin rodent model has been developed. Given the co...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/1462802
更新日期:2018-09-12 00:00:00