Abstract:
:Contrast-induced nephropathy (CIN) is now one of the three leading causes of acute kidney injury in the world. A lot is known about the risk factors of CIN, yet it remains a major cause of morbidity, end stage renal disease, prolonged hospital stay, and increased costs as well as a high mortality. Many patients undergoing contrast-based radiological investigations are treated with angiotensin converting inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) for their cardiac and renal benefits and their known mortality benefits. However, controversy exists among clinicians as to whether ACE-Is and ARBs should be continued or discontinued prior to contrast media exposure. In this paper we review the current evidence on ACE-I/ARB therapy for patients undergoing procedures involving use of contrast media and provide recommendations as to whether these drugs should be continued or held prior to contrast exposure.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Kalyesubula R,Bagasha P,Perazella MAdoi
10.1155/2014/423848subject
Has Abstractpub_date
2014-01-01 00:00:00pages
423848eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
杂志文章,评审abstract::The valorization of Crocus sativus L. by-products has become important given its interesting content of bioactive molecules. In the present study, aqueous tepal extract (ATE) studied eggplant seedling's growth and physiology under a plastic tunnel. ATE was foliage sprayed 3 times every 15 days, with various concentrat...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8812157
更新日期:2020-11-05 00:00:00
abstract::This study investigated the role of gender as a potential predictor of health behaviour and potential moderator of the relationship between emotional intelligence and health behaviour. This cross-sectional study included 1214 students (597 males and 617 females). Data were collected using the Schutte Self-Report Inven...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/7058105
更新日期:2018-06-04 00:00:00
abstract::The receptor of advanced glycation end products (RAGE) and its ligands are linked to the pathogenesis of coronary artery disease (CAD), and circulating soluble receptor of advanced glycation end products (sRAGE), reflecting the RAGE activity, is suggested as a potential biomarker. Elevated sRAGE levels are reported in...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/815942
更新日期:2015-01-01 00:00:00
abstract:Background:The purpose of this study was to examine the physical activity patterns and health-related fitness levels of adolescents within the Juvenile Justice System. Methods:Participants included 68 adolescents (Mean age = 17.1 ± 1.0 years) in two secure Juvenile Justice correctional facilities in the Western USA. M...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/9710714
更新日期:2018-07-15 00:00:00
abstract::Giardia duodenalis, is often seen as an opportunistic pathogen and one of the major food and waterborne parasites. Some insights of Giardia infestation in a diarrhoea-prone population were investigated in the present study. Our primary goal was to understand the interaction of this parasite with other pathogens during...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/786480
更新日期:2014-01-01 00:00:00
abstract::The rapid development of picture archiving and communication systems (PACSs) thoroughly changes the way of medical informatics communication and management. However, as the scale of a hospital's operations increases, the large amount of digital images transferred in the network inevitably decreases system efficiency. ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/657417
更新日期:2014-01-01 00:00:00
abstract::It is challenging and inspiring for us to achieve high spatiotemporal resolutions in dynamic cardiac magnetic resonance imaging (MRI). In this paper, we introduce two novel models and algorithms to reconstruct dynamic cardiac MRI data from under-sampled k - t space data. In contrast to classical low-rank and sparse mo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/169317
更新日期:2015-01-01 00:00:00
abstract::The aim of this study was to evaluate the safety and effectiveness of percutaneous transluminal angioplasty and stenting (PTAS) for intracranial atherosclerotic disease (ICAD) by conducting a meta-analysis. Two independent observers searched PubMed, EMBASE, and Cochrane Library for relevant studies up to 31 December 2...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2017/3258681
更新日期:2017-01-01 00:00:00
abstract:Background:Shedding of the endothelial glycocalyx layer (EGL) is known to occur during major surgery, but its degradation associated with minimally invasive video-assisted thoracoscopy (VATS) remains unclear. We investigated if serum biomarkers of EGL disruption were elevated during VATS lobectomy, and whether the urin...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1155/2017/5969657
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Noncardiac chest pain (NCCP) is seen more frequently in young population and in these patients loss of function is evolving in social and professional areas. The aim of the study is to evaluate the levels of anxiety and somatic perception in patients with chest pain presenting to cardiology clinic. METHODS:F...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2014/896183
更新日期:2014-01-01 00:00:00
abstract::28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/823829
更新日期:2015-01-01 00:00:00
abstract:Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3845780
更新日期:2019-12-14 00:00:00
abstract::Sericin is a natural protein component of silks of silkworm and has potential utility in multiple areas such as pharmacological, cosmetics, and biotechnological industries. However, the understanding of its toxicological safety is still limited. This study evaluated the safety of water-extract sericin from silkworm (B...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9689386
更新日期:2020-11-05 00:00:00
abstract::Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/3636874
更新日期:2020-10-17 00:00:00
abstract::Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2017/4359424
更新日期:2017-01-01 00:00:00
abstract::Secretory leukoprotease inhibitor (SLPI) is an anti-inflammatory protein present in respiratory secretions. Whilst epithelial cell SLPI is extensively studied, neutrophil associated SLPI is poorly characterised. Neutrophil function including chemotaxis and degranulation of proteolytic enzymes involves changes in cytos...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/560141
更新日期:2013-01-01 00:00:00
abstract::The interaction of patulin with human serum albumin (HSA) was studied in vitro under normal physiological conditions. The study was performed using fluorescence, ultraviolet-visible spectroscopy (UV-Vis), circular dichroism (CD), atomic force microscopy (AFM), and molecular modeling techniques. The quenching mechanism...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/734850
更新日期:2014-01-01 00:00:00
abstract::The availability of an active substance through the skin depends basically on two consecutive steps: the release of this substance from the vehicle and its subsequent permeation through the skin. Hence, studies on the specific properties of vehicles, such as their rheological behavior, are of great interest in the fie...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/818656
更新日期:2015-01-01 00:00:00
abstract:Background:The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by atherosclerosis with chronic inflammation in the aortic wall. Montelukast is a selective cys-LT 1 receptor antagonist that can suppress atherosclerotic diseases. We evaluated the in vitro properties of montelukast and its in vivo activit...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9104680
更新日期:2019-05-27 00:00:00
abstract::The number of RNA-Seq studies has grown in recent years. The design of RNA-Seq studies varies from very simple (e.g., two-condition case-control) to very complicated (e.g., time series involving multiple samples at each time point with separate drug treatments). Most of these publically available RNA-Seq studies are d...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/318064
更新日期:2015-01-01 00:00:00
abstract::Introduction. The triangular fibrocartilage complex (TFCC) provides both mobility and stability of the radiocarpal joint. TFCC lesions are difficult to diagnose due to the complex anatomy. The standard treatment for TFCC lesions is arthroscopy, posing surgery-related risks onto the patients. This feasibility study aim...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/5870875
更新日期:2017-01-01 00:00:00
abstract::Protein structure prediction (PSP) is computationally a very challenging problem. The challenge largely comes from the fact that the energy function that needs to be minimised in order to obtain the native structure of a given protein is not clearly known. A high resolution 20 × 20 energy model could better capture th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/924137
更新日期:2013-01-01 00:00:00
abstract::Ureteroplasty using onlay grafts or flaps emerged as an innovative procedure for the management of proximal and midureteral strictures. Autologous grafts or flaps used commonly in ureteroplasty include the oral mucosae, bladder mucosae, ileal mucosae, and appendiceal mucosae. Oral mucosa grafts, especially buccal muco...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/6178286
更新日期:2020-07-27 00:00:00
abstract:Purpose:Fractures are common among all types of paediatric injuries, with differences in incidence over time. Here, we present the epidemiologic features of traumatic fractures in a population of youth ≤ 18 years of age who were admitted to our university-affiliated hospitals from 2002 to 2010. Methods:We retrospectiv...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2019/8019063
更新日期:2019-02-20 00:00:00
abstract::With the recent advancement in the field of ocular therapy, drug delivery approaches have been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. However the major drawbacks of the conventional drug deliv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/263604
更新日期:2014-01-01 00:00:00
abstract::Abnormal metabolism is another cancer hallmark. The two most characterized altered metabolic pathways are high rates of glycolysis and glutaminolysis, which are natural targets for cancer therapy. Currently, a number of newer compounds to block glycolysis and glutaminolysis are being developed; nevertheless, lonidamin...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/690492
更新日期:2015-01-01 00:00:00
abstract::Background. With the introduction of three-dimensional (3D) ultrasound it has become possible to measure volumes. The relative increase in embryonic volume (EV) is much larger than that of the crown-rump length (CRL) over the same time period. We examined whether EV is a better parameter to determine growth restrictio...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2017/1953076
更新日期:2017-01-01 00:00:00
abstract::Hydrogel injection has been recently proposed as a novel therapy for disc degenerative diseases, with the potential to restore the spine motion and the intervertebral disc height. However, it remains unknown whether the new technique could also maintain the shock absorbing property of the treated intervertebral disc. ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/461724
更新日期:2014-01-01 00:00:00
abstract::Background. Neuroinflammation which presents as a possible mechanism of delirium is associated with MCP-1, an important proinflammatory factor which is expressed on astrocytes. It is known that dexmedetomidine (DEX) possesses potent anti-inflammatory properties. This study aimed to investigate the potential effects of...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/6352159
更新日期:2017-01-01 00:00:00
abstract::The distribution of the induced electric field (E-field) during transcranial magnetic stimulation (TMS) depends on the individual anatomical structure of the brain as well as coil positioning. Inappropriate stimulation may degrade the efficacy of TMS or even induce adverse effects. Therefore, optimizing the E-field ac...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9461018
更新日期:2019-11-03 00:00:00