Adverse Drug Reaction due to Antidepressants among Patients with Depression in a Private Psychiatric Hospital of Nepal.

abstract：:Mung bean is a hepatoprotective agent in dietary supplements. Fermentation and germination processes are well recognized to enhance the nutritional values especially the concentration of active compounds such as amino acids and GABA of various foods. In this study, antioxidant and hepatoprotective effects of freeze-dr...

journal_title：BioMed research international

authors： Mohd Ali N,Mohd Yusof H,Long K,Yeap SK,Ho WY,Beh BK,Koh SP,Abdullah MP,Alitheen NB

更新日期：2013-01-01 00:00:00

abstract：:Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...

journal_title：BioMed research international

authors： Gou H,Ye J,Wang Y,Xu X,Shen Q,Xue J,Zhao J,Lu X

更新日期：2017-01-01 00:00:00

abstract：:Purpose of this paper is to analyze different species' proportion of nontuberculosis mycobacteria (NTM) and susceptibility to clarithromycin of different species. 278 clinical NTM isolates were identified into species by using 16S rRNA, rpoB and hsp65. Then clarithromycin susceptibility testing against different speci...

journal_title：BioMed research international

authors： Nie W,Duan H,Huang H,Lu Y,Chu N

更新日期：2015-01-01 00:00:00

abstract：:Bioadhesive nasal dosage forms are an attractive method for overcoming rapid mucociliary clearance transport in the nose and for delivering the drug directly to brain. The present study was designed to formulate chondroitin sulphate (CS) and chitosan (CH) nasal inserts employing zolmitriptan, an antimigraine drug. The...

journal_title：BioMed research international

authors： Kaur K,Kaur G

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:A delayed time to pregnancy was recently reported for women who had a loop electrosurgical excision procedure (LEEP) to remove cervical intraepithelial neoplasia (CIN) grade 2 or 3. The objective of the current study was to determine if treatment of CIN with LEEP is associated with decreased levels of anti-M...

journal_title：BioMed research international

authors： Sklavos MM,Spracklen CN,Saftlas AF,Pinto LA

更新日期：2014-01-01 00:00:00

abstract：Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

journal_title：BioMed research international

authors： Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

更新日期：2019-12-14 00:00:00

abstract：:Virulence-associated traits have frequently been studied in enterococci and are considered to contribute towards the pathogenicity of infections. In the present study, Enterococcus isolates were collected during diagnostic investigations from meat turkeys in Germany. Twenty-eight isolates of three different Enterococc...

journal_title：BioMed research international

authors： Maasjost J,Lüschow D,Kleine A,Hafez HM,Mühldorfer K

更新日期：2019-10-30 00:00:00

abstract：Background:It is well known that the programmed intermittent epidural bolus (PIEB) technique effectively provides epidural anesthesia in labor. This randomized double-blind trial compared the postoperative analgesic efficacy of PIEB with that of continuous epidural infusion (CEI) in patients undergoing gynecological su...

journal_title：BioMed research international

authors： Satomi S,Kakuta N,Murakami C,Sakai Y,Tanaka K,Tsutsumi YM

更新日期：2018-05-15 00:00:00

abstract：:Increasing studies have revealed that long noncoding RNAs (lncRNAs) are not transcriptional noise but play important roles in the regulation of a wide range of biological processes, and the dysregulation of lncRNA genes is associated with disease development. Alzheimer's disease (AD) is a chronic neurodegenerative dis...

journal_title：BioMed research international

authors： Wan G,Zhou W,Hu Y,Ma R,Jin S,Liu G,Jiang Q

更新日期：2016-01-01 00:00:00

abstract：:There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...

journal_title：BioMed research international

authors： Paldino E,Tesori V,Casalbore P,Gasbarrini A,Puglisi MA

更新日期：2014-01-01 00:00:00

abstract：:Pediatric myelodysplastic syndrome (MDS) is an uncommon disease and little is known about the molecular alterations of its development and evolution to acute myeloid leukemia (AML). The Enhancer of Zeste Homolog 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 (PCR2). It is a histone methyltransferas...

journal_title：BioMed research international

authors： de Souza Fernandez T,Fonseca Alvarenga T,Almeida Antônio de Kós E,Lamim Lovatel V,Tavares RC,da Costa ES,de Souza Fernandez C,Abdelhay E

更新日期：2019-12-10 00:00:00

abstract：:Background. With the introduction of three-dimensional (3D) ultrasound it has become possible to measure volumes. The relative increase in embryonic volume (EV) is much larger than that of the crown-rump length (CRL) over the same time period. We examined whether EV is a better parameter to determine growth restrictio...

journal_title：BioMed research international

authors： Baken L,Benoit B,Koning AHJ,van der Spek PJ,Steegers EAP,Exalto N

更新日期：2017-01-01 00:00:00

abstract：Background:Haemonchus contortus, the causative agent of Haemonchosis, is the most economically important parasite in small ruminant production. Control with chemotherapy has not been successful due to rapid emergence of drug-resistant strains. There is a continuous search for alternative leads particularly from plants....

journal_title：BioMed research international

authors： Zenebe S,Feyera T,Assefa S

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to trigger the expression of genes related to oocytes in putative ovarian stem cells scraped from the ovarian surface epithelium of women with premature ovarian failure and cultured in vitro in the presence of follicular fluid, rich in substances for oocyte growth and maturation. Ovarian surf...

journal_title：BioMed research international

authors： Virant-Klun I,Skutella T,Kubista M,Vogler A,Sinkovec J,Meden-Vrtovec H

更新日期：2013-01-01 00:00:00

abstract：:Taenia solium thioredoxin-1 gene (TsTrx-1) has a length of 771 bp with three exons and two introns. The core promoter gene presents two putative stress transcription factor binding sites, one putative TATA box, and a transcription start site (TSS). TsTrx-1 mRNA is expressed higher in larvae than in adult. This gene en...

journal_title：BioMed research international

authors： Jiménez L,Rodríguez-Lima O,Ochoa-Sánchez A,Landa A

更新日期：2015-01-01 00:00:00

abstract：:Effective alteration of the recalcitrance properties like crystallization of cellulose, lignin shield, and interlinking of lignocellulosic biomass is an ideal way to utilize the full-scale potential for biofuel production. This study exhibited three different pretreatment effects to enhance the digestibility of corn s...

journal_title：BioMed research international

authors： Siddhu MA,Li J,Zhang J,Huang Y,Wang W,Chen C,Liu G

更新日期：2016-01-01 00:00:00

abstract：:The aim of the study was to comparatively evaluate the fracture strength and mode of root canal treated teeth restored with resin composites with and without posts. The lingual cusps of root canal treated first upper premolars (n = 10/group) were removed down to cervical enamel and restored with the following: group A...

journal_title：BioMed research international

authors： Gaintantzopoulou MD,Farmakis ET,Eliades GC

更新日期：2018-08-14 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：BACKGROUND:Inflammation has a key role in migraine pathophysiology. Vitamin D is an effective anti-inflammatory agent. The aim of this study was to investigate the association between migraine and two vitamin D receptor (VDR) polymorphisms (TaqI and FokI) and also the relationship between VDR polymorphisms and headache...

journal_title：BioMed research international

authors： Motaghi M,Haghjooy Javanmard S,Haghdoost F,Tajadini M,Saadatnia M,Rafiee L,Zandifar A

更新日期：2013-01-01 00:00:00

abstract：:The effect of crocetin (C20H24O4) on methylcholanthrene- (MCA-) induced uterine cervical cancer in mice was studied in this paper. After the mice were treated orally with crocetin, maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were examined by ELISA...

journal_title：BioMed research international

authors： Chen B,Hou ZH,Dong Z,Li CD

更新日期：2015-01-01 00:00:00

abstract：:HPV genotypes have distinct distributions among various ethnic populations worldwide. In December 2013, 237 and 159 cervical samples were collected from Hani and Han ethnic women, respectively, in Mojiang, a rural county in southern Yunnan. The overall HPV infection rate (21.1%) among the Hani women was significantly ...

journal_title：BioMed research international

authors： Baloch Z,Yue L,Yuan T,Feng Y,Tai W,Liu Y,Wang B,Li X,Liu L,Zhang AM,Wu X,Xia X

更新日期：2015-01-01 00:00:00

abstract：:Family planning coverage has improved in Ethiopia in the last decade, though fertility is still about 5.8 in the rural setup. In this paper, the major structural determinants of family planning service were analyzed using a multilevel model from 8906 individual women observation in the 2011 EDHS data. The results show...

journal_title：BioMed research international

authors： Gizachew Balew J,Cho Y,Tammy Kim C,Ko W

更新日期：2015-01-01 00:00:00

abstract：:Scaffolds play an important role in tissue engineering and their structure and biocompatibility have great influence on cell behaviors. In this study, poly(l-lactide-co-ε-caprolactone) (PLCL) scaffolds were printed by a 3D printing technology, low-temperature deposition manufacturing (LDM), and then PLCL scaffolds wer...

journal_title：BioMed research international

authors： He Y,Liu W,Guan L,Chen J,Duan L,Jia Z,Huang J,Li W,Liu J,Xiong J,Liu L,Wang D

更新日期：2018-02-28 00:00:00

abstract：:The biological age (BA) equation is a prediction model that utilizes an algorithm to combine various biological markers of ageing. Different from traditional concepts, the BA equation does not emphasize the importance of a golden index but focuses on using indices of vital organs to represent the senescence of whole b...

journal_title：BioMed research international

authors： Jia L,Zhang W,Jia R,Zhang H,Chen X

更新日期：2016-01-01 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：:Ischemia-reperfusion injury (IRI) is a major contributor to acute kidney injury (AKI). At present, there are no effective therapies to prevent AKI. The aim of this study was to analyse whether valproic acid (VPA), a histone deacetylase inhibitor with anti-inflammatory properties, prevents renal IRI. Male Wistar rats w...

journal_title：BioMed research international

authors： Costalonga EC,Silva FM,Noronha IL

更新日期：2016-01-01 00:00:00

abstract：:To explore the mechanisms by which andrographolide inhibits gastric cancer cell proliferation and metastasis, we employed the gastric cell line SGC7901 to investigate the anticancer effects of andrographolide. The cell survival ratio, cell migration and invasion, cell cycle, apoptosis, and matrix metalloproteinase act...

journal_title：BioMed research international

authors： Dai L,Wang G,Pan W

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The aims of this study were to evaluate the complications that occur after trauma and the characteristics of individuals who develop complications, to identify potential risk factors that increase their incidence, and finally to investigate the relationship between complications and mortality. METHODS:We di...

journal_title：BioMed research international

authors： Mondello S,Cantrell A,Italiano D,Fodale V,Mondello P,Ang D

更新日期：2014-01-01 00:00:00

abstract：:Large amounts of various biological networks exist for representing different types of interaction data, such as genetic, metabolic, gene regulatory, and protein-protein relationships. Recent approaches on biological network study are based on different mathematical concepts. It is necessary to construct a uniform fra...

journal_title：BioMed research international

authors： Cao Y,Xu W,Niu C,Bo X,Li F

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:Isoniazid (INH), a key agent in the treatment of tuberculosis (TB), is metabolized primarily by the genetically polymorphic N-acetyltransferase 2 (NAT2) enzyme. Patients treated with INH can be classified as fast, intermediate, and slow acetylators. The objective of this study was to explore the relationship...

journal_title：BioMed research international

authors： Zabost A,Brzezińska S,Kozińska M,Błachnio M,Jagodziński J,Zwolska Z,Augustynowicz-Kopeć E

更新日期：2013-01-01 00:00:00