Abstract:
Aims:To evaluate the effectiveness and safety of peritoneal dialysis (PD) in treating refractory congestive heart failure (RCHF) with cardiorenal syndrome (CRS). Methods:A total of 36 patients with RCHF were divided into type 2 CRS group (group A) and non-type 2 CRS group (group B) according to the patients' clinical presentations and the ratio of serum urea to creatinine and urinary analyses in this prospective study. All patients were followed up till death or discontinuation of PD. Data were collected for analysis, including patient survival time on PD, technique failure, changes of heart function, and complications associated with PD treatment and hospitalization. Results:There were 27 deaths and 9 patients quitting PD program after a follow-up for 73 months with an average PD time of 22.8 ± 18.2 months. A significant longer PD time was found in group B as compared with that in group A (29.0 ± 19.4 versus 13.1 ± 10.6 months, p = 0.003). Kaplan-Meier curves showed a higher survival probability in group B than that in group A (p < 0.001). Multivariate regression demonstrated that type 2 CRS was an independent risk factor for short survival time on PD. The benefit of PD on the improvement of survival and LVEF was limited to group B patients, but absent from group A patients. The impairment of exercise tolerance indicated by NYHA classification was markedly improved by PD for both groups. The technique survival was high, and the hospital readmission was evidently decreased for both group A and group B patients. Conclusions:Our data suggest that PD is a safe and feasible palliative treatment for RCHF with type 2 CRS, though the long-term survival could not be expected for patients with the type 2 CRS. Registration ID Number is ChiCTR1800015910.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Shao Q,Xia Y,Zhao M,Liu J,Zhang Q,Jin B,Xie J,Xu B,Gong R,Jiang Cdoi
10.1155/2018/6529283subject
Has Abstractpub_date
2018-05-17 00:00:00pages
6529283eissn
2314-6133issn
2314-6141journal_volume
2018pub_type
临床试验,杂志文章abstract:PURPOSE:To quantitatively measure changes in cerebral perfusion in select regions of interest in the brain during urinary urgency in women with overactive bladder (OAB) using arterial spin labeling (ASL). METHODS:Twelve women with OAB and 10 controls underwent bladder filling and rated urinary urgency (scale 0-10). AS...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2759035
更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/206581
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abstract::Macrophages, especially their activation state, are closely related to the progression of diabetic nephropathy. Classically activated macrophages (M1) are proinflammatory effectors, while alternatively activated macrophages (M2) exhibit anti-inflammatory properties. 1,25-Dihydroxyvitamin D3 has renoprotective roles th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/157834
更新日期:2015-01-01 00:00:00
abstract::Artery calcification is a well-recognized predictor of late atherosclerotic complications. In the intima media, calcification starts with apoptosis of vascular smooth muscle cells (VSMCs) and the release of calcifying matrix vesicles with diameter of 0.5-15 μm that can be observed microscopically. In complicated plaqu...
journal_title:BioMed research international
pub_type: 杂志文章,评审
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journal_title:BioMed research international
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doi:10.1155/2018/1293124
更新日期:2018-07-08 00:00:00
abstract::Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...
journal_title:BioMed research international
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/712312
更新日期:2014-01-01 00:00:00
abstract::The future development of shrimp farming needs to improve its ecoefficiency. The purpose of this study was to evaluate water quality, flows, and nitrogen balance and production parameters on a farm with interconnected pond design to improve the efficiency of the semi-intensive culture of Litopenaeus vannamei ponds. Th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/873748
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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journal_title:BioMed research international
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5024942
更新日期:2020-06-27 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8270187
更新日期:2019-10-07 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3892685
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/3769245
更新日期:2017-01-01 00:00:00
abstract::Multiparametric MRI of the prostate combines high-resolution anatomic imaging with functional imaging of alterations in normal tissue caused by neoplastic transformation for the identification and characterization of in situ prostate cancer. Lesion detection relies on a systematic approach to the analysis of both anat...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/684127
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/735672
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/4570351
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journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
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journal_title:BioMed research international
pub_type: 杂志文章,评审
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更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2020-01-25 00:00:00
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journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2015/878517
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journal_title:BioMed research international
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2957941
更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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abstract::Tantalum rod implantation with vascularized iliac grafting has been reported to be an effective method for the treatment of young patients with osteonecrosis of the femoral head (ONFH) to avert the need for total hip arthroplasty (THA). However, there have been unsatisfactory success rates for end-stage ONFH. The auth...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2015/240506
更新日期:2015-01-01 00:00:00