The Role of Biologically Active Ingredients from Natural Drug Treatments for Arrhythmias in Different Mechanisms.

abstract：:This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...

journal_title：BioMed research international

authors： Abdel Aziz MT,Khaled HM,El Hindawi A,Roshdy NK,Rashed LA,Sabry D,Hassouna AA,Taha F,Ali WI

更新日期：2013-01-01 00:00:00

abstract：:Toll-like receptors (TLRs) play a key role in the innate immune response to numerous pathogens, including Acanthamoeba spp. The aim of this study was to determine the expression of TLR2 and TLR4 in the eyes of mice following intranasal infection with Acanthamoeba spp. in relation to the host's immunological status. Am...

journal_title：BioMed research international

authors： Kot K,Kosik-Bogacka D,Łanocha-Arendarczyk N,Wojtkowiak-Giera A,Kolasa-Wołosiuk A

更新日期：2019-06-12 00:00:00

abstract：:Multiple sclerosis (MS) is an inflammatory demyelinating disease of the human central nervous system (CNS). Neurotropic demyelinating strain of MHV (MHV-A59 or its isogenic recombinant strain RSA59) induces MS-like disease in mice mediated by microglia, along with a small population of T cells. The mechanism of demyel...

journal_title：BioMed research international

authors： Kishore A,Kanaujia A,Nag S,Rostami AM,Kenyon LC,Shindler KS,Das Sarma J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:It is well established that the Mediterranean and Arab populations are at high risk for thalassemias in general and for alpha-thalassemia in particular. Yet, reports on alpha-thalassemia in Lebanon are still lacking. In this study, we aim at assessing the incidence of alpha-thalassemia in the Lebanese popula...

journal_title：BioMed research international

authors： Farra C,Daher R,Badra R,el Rafei R,Bejjany R,Charafeddine L,Yunis K

更新日期：2015-01-01 00:00:00

abstract：Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...

journal_title：BioMed research international

authors： Tsai WC,Lin HC,Lai YR,Hsu CW,Huang CC,Wang HC,Su CM,Su YJ,Lin WC,Cheng BC,Chang WN,Lu CH,Tsai NW

更新日期：2019-04-18 00:00:00

abstract：Background:Uveitis is a known ophthalmologic manifestation of seronegative spondyloarthropathy, including psoriatic arthritis. However, the data is less clear among patients with psoriasis due to the limited number of published studies. Aims:To investigate whether the risk of incident and prevalent uveitis is elevated...

journal_title：BioMed research international

authors： Chaiyabutr C,Ungprasert P,Silpa-Archa N,Wongpraparut C,Chularojanamontri L

更新日期：2020-07-15 00:00:00

abstract：:5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...

journal_title：BioMed research international

authors： Zhu Y,Xu L,Fan Y,Li C,Zhang Y,Zheng H,Hou K,Qu X,Liu Y

更新日期：2013-01-01 00:00:00

abstract：:Recently, cardiovascular disease, also known as loop circulatory system diseases or disorders, is one of the serious diseases including heart disease, stroke, atherosclerosis, myocardial infarction, hypertension, hypotension, and thrombosis. Human pregnane X receptor, PXR, plays a crucial role in exogenous and endobio...

journal_title：BioMed research international

authors： Chen KB,Chen HY,Chen KC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:Spinal cord injury (SCI) is a highly debilitating disease and is increasingly being recognized as an important global health priority. However, the mechanisms underlying SCI have not yet been fully elucidated, and effective therapies for SCI are lacking. Long noncoding RNAs (lncRNAs), which form a major class of nonco...

journal_title：BioMed research international

authors： Wang F,Liu J,Wang X,Chen J,Kong Q,Ye B,Li Z

更新日期：2019-10-15 00:00:00

abstract：:IL-1 family includes IL-38 (IL-1F10) and the subfamily of IL-36 and is the central mediators of inflammatory diseases, including pustular psoriasis, atopic dermatitis, rheumatoid arthritis, and gut inflammation. The purpose of the study was to evaluate on tissue of the patients with inflammatory bowel disease (IBD), t...

journal_title：BioMed research international

authors： Fonseca-Camarillo G,Furuzawa-Carballeda J,Iturriaga-Goyon E,Yamamoto-Furusho JK

更新日期：2018-12-10 00:00:00

abstract：:Cigarette smoke is highly toxic, and it can promote increased production of reactive species and inflammatory response and leads to liver diseases. Quercetin is a flavonoid that displays antioxidant and anti-inflammatory activities in liver diseases. This study aimed at evaluating the protective effects of quercetin o...

journal_title：BioMed research international

authors： Machado-Junior PA,Araújo NPS,Souza ABF,Castro TF,Oliveira M,Costa GP,Matos NA,Vieira PMA,Talvani A,Bezerra FS,Cangussú SD

更新日期：2020-11-15 00:00:00

abstract：:Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...

journal_title：BioMed research international

authors： Haass NK,Nassif N,McGowan EM

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2643862.]. ...

journal_title：BioMed research international

authors： Cheng LG,He W,Zhang HX,Song Q,Ning B,Li HZ,He Y,Lin S

更新日期：2017-01-01 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a multisystemic granulomatous disorder characterized by multiple noncaseating granulomas involving intrathoracic lymph nodes and lung parenchyma. Recently, the use of anti-tumor necrosis factor alpha (anti-TNFα) agents has been introduced for therapy of chronic and refractory sarcoidosis wit...

journal_title：BioMed research international

authors： Galli F,Lanzolla T,Pietrangeli V,Malviya G,Ricci A,Bruno P,Ragni P,Scopinaro F,Mariotta S,Signore A

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the behaviour of breast c...

journal_title：BioMed research international

authors： Sasi W,Ye L,Jiang WG,Sharma AK,Mokbel K

更新日期：2014-01-01 00:00:00

abstract：:A prospective nonrandomized controlled study was conducted to explore the association between ocular dominance and degree of myopia in patients with anisometropia and to investigate the character of visual evoked potential (VEP) in high anisometropias. 1771 young myopia cases including 790 anisometropias were recruite...

journal_title：BioMed research international

authors： Wang Q,Wu Y,Liu W,Gao L

更新日期：2016-01-01 00:00:00

abstract：:In the present study, the biobleaching potential of white rot fungus Cordyceps militaris MTCC3936 was investigated. For preliminary screening, decolorization properties of C. militaris were comparatively studied using whole cells in agar-based and liquid culture systems. Preliminary investigation in liquid culture sys...

journal_title：BioMed research international

authors： Kaur B,Kumar B,Garg N,Kaur N

更新日期：2015-01-01 00:00:00

abstract：:The endoscopic and histopathological findings detected in Sparus aurata experimentally infected with third-stage Anisakis larvae without intermediate host are evaluated and discussed. In six fish, live nematode larvae were introduced by gastroscopy into the stomach. The first observation by endoscope, 15 days after ch...

journal_title：BioMed research international

authors： Marino F,Lanteri G,Passantino A,De Stefano C,Costa A,Gaglio G,Macrì F

更新日期：2013-01-01 00:00:00

abstract：:Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and expression of ICAM-1 mRNA in cells of the monocyte/macrophage system...

journal_title：BioMed research international

authors： Paulsen K,Tauber S,Dumrese C,Bradacs G,Simmet DM,Gölz N,Hauschild S,Raig C,Engeli S,Gutewort A,Hürlimann E,Biskup J,Unverdorben F,Rieder G,Hofmänner D,Mutschler L,Krammer S,Buttron I,Philpot C,Huge A,Lier H,Barz

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous...

journal_title：BioMed research international

authors： Chai M,Walker SP,Riley C,Rice GE,Permezel M,Lappas M

更新日期：2013-01-01 00:00:00

abstract：:The differential effects of a selective kappa- (κ-) opioid receptor agonist, U50488, were elucidated by monitoring the contraction of isolated guinea pig atrial and ventricular muscles. In electrically driven left atria, U50488 in nanomolar concentration range decreased the contractile force. Norbinaltorphimine (norBN...

journal_title：BioMed research international

authors： Hung CF,Li HJ,Chang HH,Lee GA,Su MJ

更新日期：2015-01-01 00:00:00

abstract：:The study aimed to determine the suitability of testing the saliva of kickboxing athletes to show changes in biochemical parameters in dynamic of training. 8 elite male athletes (mean age 17.29± 0.31 years, body mass 66.82± 3.46kg, with 5.62±0.96 years of training experience) participated in the study. Indicators of l...

journal_title：BioMed research international

authors： Volodchenko OA,Podrigalo LV,Iermakov SS,Żychowska MT,Jagiełło W

更新日期：2019-01-10 00:00:00

abstract：:Hypoxia plays an essential role in orchestrating Epithelial-mesenchymal transition and promoting metastasis of colorectal cancer. However, the underlying mechanisms are still not well elucidated. Here, we present that hypoxic exposure causes endoplasmic reticulum stress and activates the unfolded protein response path...

journal_title：BioMed research international

authors： Zheng H,Wu Y,Guo T,Liu F,Xu Y,Cai S

更新日期：2020-01-27 00:00:00

abstract：Background and Aim:ROHHADNET (rapid-onset obesity with hypoventilation, hypothalamic, autonomic dysregulation, neuroendocrine tumor) syndrome is a rare disease with grave outcome. Although early recognition is essential, prompt diagnosis may be challenging due to its extreme rarity. This study aimed to systematically r...

journal_title：BioMed research international

authors： Lee JM,Shin J,Kim S,Gee HY,Lee JS,Cha DH,Rim JH,Park SJ,Kim JH,Uçar A,Kronbichler A,Lee KH,Shin JI

更新日期：2018-11-21 00:00:00

abstract：:Angiopoietin-like protein 4 (ANGPTL4) is widely known as a key regulator of lipid metabolism. We investigated the relationship between ANGPTL4 expression in serum or urine and blood lipid or urine protein levels of patients with hyperlipidemia- (HL-) related proteinuria. Sixty-eight patients with HL-related proteinuri...

journal_title：BioMed research international

authors： Gao X,Zhang M,Feng W,Xu Z,Wang Y,Shi L,Zhang J

更新日期：2020-03-23 00:00:00

abstract：:Myofascial pain syndrome is characterized by pain and a limited range of joint motion caused by muscle contracture related to motor-end-plate dysfunction and the presence of myofascial trigger points (MTrPs). It is the most frequent cause of musculoskeletal pain, with a worldwide prevalence varying between 13.7% and 4...

journal_title：BioMed research international

authors： Wada JT,Akamatsu F,Hojaij F,Itezerote A,Scarpa JC,Andrade M,Jacomo A

更新日期：2020-01-22 00:00:00

abstract：:Three bioactive fractions, extracellular laccase (ex-LAC), crude endopolysaccharides (c-EPL), and a low molecular subfraction of secondary metabolites (ex-LMS), were isolated from the idiophasic cultures of the white rot fungus Cerrena unicolor. For the first time, we determined the antioxidant properties of these sam...

journal_title：BioMed research international

authors： Jaszek M,Osińska-Jaroszuk M,Janusz G,Matuszewska A,Stefaniuk D,Sulej J,Polak J,Ruminowicz M,Grzywnowicz K,Jarosz-Wilkołazka A

更新日期：2013-01-01 00:00:00

abstract：:Introduction. In the field of orthopaedic surgery, the use of osteogenic material in larger defects is essential. Autograft and allograft are both known methods, and autograft is believed to be the best choice. But autograft is associated with additional invasive procedures which can prove difficult in fragile patient...

journal_title：BioMed research international

authors： Dreyer CH,Rasmussen M,Pedersen RH,Overgaard S,Ding M

更新日期：2020-03-03 00:00:00

abstract：:In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of anticoagulants tha...

journal_title：BioMed research international

authors： Sulimov VB,Gribkova IV,Kochugaeva MP,Katkova EV,Sulimov AV,Kutov DC,Shikhaliev KS,Medvedeva SM,Krysin MY,Sinauridze EI,Ataullakhanov FI

更新日期：2015-01-01 00:00:00