Treatment of cardiovascular disease by traditional Chinese medicine against pregnane X receptor.

abstract：:The aim of this study was to develop a freeze-drying protocol facilitating successful processing of plant material containing the small surface antigen of hepatitis B virus (S-HBsAg) while preserving its VLP structure and immunogenicity. Freeze-drying of the antigen in lettuce leaf tissue, without any isolation or pur...

journal_title：BioMed research international

authors： Czyż M,Dembczyński R,Marecik R,Wojas-Turek J,Milczarek M,Pajtasz-Piasecka E,Wietrzyk J,Pniewski T

更新日期：2014-01-01 00:00:00

abstract：:We discuss some aspects of the fluid dynamics of vitreous substitutes in the vitreous chamber, focussing on the flow induced by rotations of the eye bulb. We use simple, yet not trivial, theoretical models to highlight mechanical concepts that are relevant to understand the dynamics of vitreous substitutes and also to...

journal_title：BioMed research international

authors： Isakova K,Pralits JO,Repetto R,Romano MR

更新日期：2014-01-01 00:00:00

abstract：:Cardiovascular diseases (CVDs) are considered to be the predominant cause of death in the world. Chinese herb medicines (CHMs) have been widely used for the treatment of CVDs in Asian countries for thousands of years. One reason of high efficacy of CHMs in treating CVDs is attributed to their inhibition in atheroscler...

journal_title：BioMed research international

authors： Lu L,Sun X,Qin Y,Guo X

更新日期：2018-06-13 00:00:00

abstract：:Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...

journal_title：BioMed research international

authors： Lee S,Kim Y,Kwon MS,Park T

更新日期：2015-01-01 00:00:00

abstract：:Purpose. To compare the results of extracorporeal shock wave therapy (ESWT) for insertional Achilles tendinopathy (IAT) with or without Haglund's deformity. Methods. Between September 2014 and May 2015, all patients who underwent ESWT were retrospectively enrolled in this study. A total of 67 patients were available f...

journal_title：BioMed research international

authors： Wu Z,Yao W,Chen S,Li Y

更新日期：2016-01-01 00:00:00

abstract：:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial isch...

journal_title：BioMed research international

authors： Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

更新日期：2017-01-01 00:00:00

abstract：Aim:The aim of this study is to detect the prevalence of substance use among tenth-grade students; their thoughts, attitudes, behaviors, and tendencies towards substance use; and risk factors of substance use in tenth-grade students in general. Methods:This study is descriptive and cross-sectional conducted between Ap...

journal_title：BioMed research international

authors： Öztaş D,Kalyon A,Ertuğrul A,Gündoğdu Ç,Balcıoğlu H,Sağlan Y,Bilge U,Karahan S

更新日期：2018-03-15 00:00:00

abstract：:Based on low carbon wastewater as the research object and using corncob as an external solid carbon source, the performance of corncob organic matter was assessed for its release potential, quantity of release, and safety of use. The effects of varying quantities of the solid carbon source on simultaneous nitrificatio...

journal_title：BioMed research international

authors： Zhang LQ,He PF,Wu D,Li SG,Huang YL,Huang YW,Wang DM

更新日期：2017-01-01 00:00:00

abstract：Background:Gegen Qinlian (GGQL) decoction is a common Chinese herbal compound for the treatment of ulcerative colitis (UC). In this study, we aimed to identify its molecular target and the mechanism involved in UC treatment by network pharmacology and molecular docking. Material and Methods. The active ingredients of P...

journal_title：BioMed research international

authors： Wei M,Li H,Li Q,Qiao Y,Ma Q,Xie R,Wang R,Liu Y,Wei C,Li B,Zheng C,Sun B,Yu B

更新日期：2020-11-24 00:00:00

abstract：:Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic meth...

journal_title：BioMed research international

authors： Wu W,Wu S,Zhou Z,Zhang R,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：:Amylase is an industrially important enzyme and applied in many industrial processes such as saccharification of starchy materials, food, pharmaceutical, detergent, and textile industries. This research work deals with the optimization of fermentation conditions for α-amylase production from thermophilic bacterial str...

journal_title：BioMed research international

authors： Simair AA,Qureshi AS,Khushk I,Ali CH,Lashari S,Bhutto MA,Mangrio GS,Lu C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Noninvasive tools to diagnose nonalcoholic fatty liver disease (NAFLD), including transient elastography (TE) and enhanced liver fibrosis panel (ELF), have only been evaluated in children with biopsy-proven NAFLD. We evaluated the prevalence of ELF and TE abnormalities in obese children without clinical live...

journal_title：BioMed research international

authors： Goldschmidt I,Di Nanni A,Streckenbach C,Schnell K,Danne T,Baumann U

更新日期：2015-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder with two hallmarks: β-amyloid plagues and neurofibrillary tangles. It is one of the most alarming illnesses to elderly people. No effective drugs and therapies have been developed, while mechanism-based explorations of therapeutic approaches have bee...

journal_title：BioMed research international

authors： Jia Q,Deng Y,Qing H

更新日期：2014-01-01 00:00:00

abstract：:The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...

journal_title：BioMed research international

authors： Martínez-Torteya A,Treviño V,Tamez-Peña JG

更新日期：2015-01-01 00:00:00

abstract：:Long noncoding RNAs play an essential role in bladder cancer progression. The role of long noncoding RNA EGFR-AS1 in bladder cancer needs further study. We used clinical specimens to analyze the relationship between EGFR-AS1 and bladder cancer patients' characteristics. The functional experiments and mechanism studies...

journal_title：BioMed research international

authors： Wang A,Jiang A,Gan X,Wang Z,Huang J,Dong K,Liu B,Wang L,Chen M

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:We aimed to identify certain genes related to response to infliximab (IFX) and biomarkers to predict the IFX effect for Japanese Crohn's disease (CD) patients by performing an association study of single nucleotide polymorphisms (SNPs) in candidate genes in the interleukin- (IL-) 17 signaling pathway with re...

journal_title：BioMed research international

authors： Urabe S,Isomoto H,Ishida T,Maeda K,Inamine T,Kondo S,Higuchi N,Sato K,Uehara R,Yajima H,Machida H,Chen CC,Fukuda Y,Takeshima F,Nakao K,Tsukamoto K

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was to investigate the effects of selective inducible nitric oxide synthase and neuronal nitric oxide synthase inhibitors on cartilage regeneration. The study involved 27 Wistar rats that were divided into five groups. On Day 1, both knees of 3 rats were resected and placed in a formalin so...

journal_title：BioMed research international

authors： Gokay NS,Yilmaz I,Komur B,Demiroz AS,Gokce A,Dervisoglu S,Gokay BV

更新日期：2016-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2015/714230.]. ...

journal_title：BioMed research international

authors： Voss JO,Loebel C,Bara JJ,Fuessinger MA,Duttenhoefer F,Alini M,Stoddart MJ

更新日期：2016-01-01 00:00:00

abstract：:The cytosolic isozyme of phosphoenolpyruvate carboxykinase (PCK1) was the first rate-limiting enzyme in the gluconeogenesis pathway, which exerted a critical role in maintaining the blood glucose levels. PCK1 has been established to be involved in various physiological and pathological processes, including glucose met...

journal_title：BioMed research international

authors： Yuan Y,Lin JY,Cui HJ,Zhao W,Zheng HL,Jiang ZW,Xiong XD,Xu S,Liu XG

更新日期：2020-02-12 00:00:00

abstract：:Previous studies have shown the therapeutic properties of ginseng and ginsenosides on hyperactive and impulsive behaviors in several psychiatric diseases. Herein, we investigated the effect of Panax ginseng Meyer (PG) on hyperactive/impulsive behaviors in a manic-like animal model, sleep deprivation (SD) rats. Male ra...

journal_title：BioMed research international

authors： Leem KH,Kim SA,Park HJ

更新日期：2020-10-17 00:00:00

abstract：PURPOSE:Electrical Bioimpedance Cerebral Monitoring is assessment in real time of health of brain tissue through study of passive dielectric properties of brain. During the last two decades theory and technology have been developed in parallel with animal experiments aiming to confirm feasibility of using bioimpedance-...

journal_title：BioMed research international

authors： Seoane F,Reza Atefi S,Tomner J,Kostulas K,Lindecrantz K

更新日期：2015-01-01 00:00:00

abstract：:A bioenergetical analysis of swimming at intensities near competitive distances is inexistent. It was aimed to compare the transient VO2 kinetics responses and metabolic contributions whilst swimming at different velocities around VO2max. 12 trained male swimmers performed (i) an incremental protocol to determine the ...

journal_title：BioMed research international

authors： Sousa AC,Vilas-Boas JP,Fernandes RJ

更新日期：2014-01-01 00:00:00

abstract：:A wide range of molecular techniques have been developed for genotyping Candida species. Among them, multilocus sequence typing (MLST) and microsatellite length polymorphisms (MLP) analysis have recently emerged. MLST relies on DNA sequences of internal regions of various independent housekeeping genes, while MLP iden...

journal_title：BioMed research international

authors： Spampinato C,Leonardi D

更新日期：2013-01-01 00:00:00

abstract：:Three novel low molecular weight polysaccharides (RLP-1a, RLP-2a, and RLP-3a) with 9004, 8761, and 7571 Da were first obtained by purifying the crude polysaccharides from the fruits of a traditional Chinese medicinal herb Rosae Laevigatae. The conditions for polysaccharides from the R. Laevigatae fruit (RLP) extractio...

journal_title：BioMed research international

authors： Zhang X,Hu Y,Jin C,Wu W

更新日期：2020-10-22 00:00:00

abstract：Methods:In the study, we included 86 children diagnosed with atopic asthma (n = 25), allergic rhinitis (n = 20), and atopic dermatitis (n = 20) and healthy control subjects (n = 21) of Caucasian origin from the Polish population. The blood leukocyte expression of 31 genes involved in neuroinflammatory response (neurotr...

journal_title：BioMed research international

authors： Sobkowiak P,Langwiński W,Nowakowska J,Wojsyk-Banaszak I,Szczepankiewicz D,Jenerowicz D,Wasilewska E,Bręborowicz A,Szczepankiewicz A

更新日期：2020-06-10 00:00:00

abstract：Background:Antiretroviral therapy transformed HIV infection into a chronic disease but accelerated cardiovascular disease (CVD). Both of epicardial adipose tissue (EAT) and pericardial fat (PCF) have close relationships with CVD. The associations between these two cardiac adipose tissue and HIV are unclear. Methods:El...

journal_title：BioMed research international

authors： Song G,Qiao W,Sun L,Yu X

更新日期：2020-12-09 00:00:00

abstract：:Natural medical plant is considered as a good source of tyrosinase inhibitors. Red vine leaf extract (RVLE) can be applied to a wide variety of medical disciplines, such as treatments for chronic venous insufficiency over many decades. This study investigated the tyrosinase inhibitory activity of RVLE containing galli...

journal_title：BioMed research international

authors： Lin YS,Chen HJ,Huang JP,Lee PC,Tsai CR,Hsu TF,Huang WY

更新日期：2017-01-01 00:00:00

abstract：:Chlamydophila psittaci (C. psittaci) is a human zoonotic pathogen, which could result in severe respiratory disease. In the present study, we investigated the role and mechanism of the type III secretion system (T3SS) of C. psittaci in regulating the inflammatory response in host cells. C. psittaci-infected THP-1 cell...

journal_title：BioMed research international

authors： He QZ,Zeng HC,Huang Y,Hu YQ,Wu YM

更新日期：2015-01-01 00:00:00

abstract：:There is a controversial relationship between HLA-A2 and Alzheimer's disease (AD). It has been suggested a modifier effect on the risk that depends on genetic loadings. Thus, the aims of this study were to evaluate this relationship and to reveal genes associated with both concepts the HLA-A gene and AD. Consequently,...

journal_title：BioMed research international

authors： Cifuentes RA,Murillo-Rojas J

更新日期：2014-01-01 00:00:00