A Comparative Study on Multifactor Dimensionality Reduction Methods for Detecting Gene-Gene Interactions with the Survival Phenotype.

abstract：INTRODUCTION:While studies using various materials to overcome ischemia-reperfusion (IR) injury are becoming increasingly common, studies on the effects of botulinum toxin A (BoTA) on IR injury in musculocutaneous flaps are still limited. The purpose of this study was to examine our hypotheses that BoTA provide protect...

journal_title：BioMed research international

authors： Park TH,Park YJ

更新日期：2017-01-01 00:00:00

abstract：:The polyherbal formulation containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol ex. Maton has been used for hypertension treatment empirically. Our previous study showed its blood pressure-lowering effect on a rat model of hypertension. However, toxicit...

journal_title：BioMed research international

authors： Sholikhah EN,Mustofa M,Nugrahaningsih DAA,Yuliani FS,Purwono S,Sugiyono S,Widyarini S,Ngatidjan N,Jumina J,Santosa D,Koketsu M

更新日期：2020-03-24 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：:In the present study, we determined whether there is a delay in the eruption of permanent teeth (PT) among Filipino adolescents with stunting or thinness. Height, weight, and number of PT were recorded in 1554 Filipino 10- to 13-year-olds (711 boys; 843 girls). z-scores for height (HAZ) and body mass index (BMI) were ...

journal_title：BioMed research international

authors： Heinrich-Weltzien R,Zorn C,Monse B,Kromeyer-Hauschild K

更新日期：2013-01-01 00:00:00

abstract：:Translocations are the most common type of structural chromosomal abnormalities. Unbalanced translocations are usually found in children who present with congenital abnormalities, developmental delay, or intellectual disability. Balanced translocations are usually found in adults who frequently present with reproducti...

journal_title：BioMed research international

authors： Paththinige CS,Sirisena ND,Kariyawasam UGIU,Dissanayake VHW

更新日期：2019-04-02 00:00:00

abstract：:Craniofacial development consists of a highly complex sequence of the orchestrated growth and fusion of facial processes. It is also known that craniofacial abnormalities can be detected in 1/3 of all patients with congenital diseases. Within the various craniofacial abnormalities, orofacial clefting is one of the mos...

journal_title：BioMed research international

authors： Kurosaka H

更新日期：2015-01-01 00:00:00

abstract：:Aspergillus species originating from Greece were examined by morphological and molecular criteria to explore the diversity of this genus. The phylogenetic relationships of these species were determined using sequences from the ITS and IGS region of the nuclear rRNA gene complex, two nuclear genes ( β -tubulin (benA) a...

journal_title：BioMed research international

authors： Krimitzas A,Pyrri I,Kouvelis VN,Kapsanaki-Gotsi E,Typas MA

更新日期：2013-01-01 00:00:00

abstract：:Long-term chronic intermittent exposure to altitude hypoxia is a labor phenomenon requiring further research. Using a rat model, we examined whether this type of exposure differed from chronic exposure in terms of pulmonary artery remodeling and other features. Rats were subjected to chronic hypoxia (CH, n = 9) and lo...

journal_title：BioMed research international

authors： Brito J,Siques P,Arribas SM,López de Pablo AL,González MC,Naveas N,Arriaza K,Flores K,León-Velarde F,Pulido R,Ordenes S,López MR

更新日期：2015-01-01 00:00:00

abstract：:Keratinases are proteolytic enzymes predominantly active when keratin substrates are available that attack disulfide bridges in the keratin to convert them from complex to simplified forms. Keratinases are essential in preparation of animal nutrients, protein supplements, leather manufacture, textile processing, deter...

journal_title：BioMed research international

authors： Gopinath SC,Anbu P,Lakshmipriya T,Tang TH,Chen Y,Hashim U,Ruslinda AR,Arshad MK

更新日期：2015-01-01 00:00:00

abstract：Background:Low birth weight is the leading cause of infant and child mortality and contributes to several poor health outcomes. Proper knowledge of risk factors of low birth weight is important for identifying those mothers at risk and thereby for planning and taking appropriate actions. This study investigates factors...

journal_title：BioMed research international

authors： Hailu LD,Kebede DL

更新日期：2018-04-23 00:00:00

abstract：:Alzheimer's disease affects millions of people worldwide and incidence is expected to rise as the population ages, but no effective therapies exist despite decades of research and more than 20 known disease markers. Research has shown that Alzheimer's disease's missing heritability remains extensive with an estimated ...

journal_title：BioMed research international

authors： Ebbert MT,Ridge PG,Kauwe JS

更新日期：2015-01-01 00:00:00

abstract：:Exposure to a variety of environmental factors such as salinity, drought, metal toxicity, extreme temperature, air pollutants, ultraviolet-B (UV-B) radiation, pesticides, and pathogen infection leads to subject oxidative stress in plants, which in turn affects multiple biological processes via reactive oxygen species ...

journal_title：BioMed research international

authors： Xie X,He Z,Chen N,Tang Z,Wang Q,Cai Y

更新日期：2019-05-08 00:00:00

abstract：:Heavy metals have the potential to interact and induce several stress responses in the plants; thus, effects of heavy metal stress on DNA damages and total antioxidants level in Urtica dioica leaves and stems were investigated. The samples are sampled from areas with different metal exposition. Metal content was analy...

journal_title：BioMed research international

authors： Gjorgieva D,Kadifkova Panovska T,Ruskovska T,Bačeva K,Stafilov T

更新日期：2013-01-01 00:00:00

abstract：:The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry criteria of probe dr...

journal_title：BioMed research international

authors： Wang L,Chiang C,Liang H,Wu H,Feng W,Quinney SK,Li J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Cisplatin is an antitumor drug used in the treatment of a wide variety of malignancies. However, its primary dose-limiting side effect is kidney injury, which is a major clinical concern. To help understand mechanisms involved in the development of kidney injury, cisplatin rodent model has been developed. Given the co...

journal_title：BioMed research international

authors： Perše M,Večerić-Haler Ž

更新日期：2018-09-12 00:00:00

abstract：:Photosystem II photochemistry and phycobiliprotein (PBP) genes of red algae Kappaphycus alvarezii, raw material of κ -carrageenan used in food and pharmaceutical industries, were analyzed in this study. Minimum saturating irradiance (I k) of this algal species was less than 115 μmol m(-2) s(-1). Its actual PSII effici...

journal_title：BioMed research international

authors： Guan X,Wang J,Zhu J,Yao C,Liu J,Qin S,Jiang P

更新日期：2013-01-01 00:00:00

abstract：:Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmis...

journal_title：BioMed research international

authors： Reis Machado J,da Silva MV,Cavellani CL,dos Reis MA,Monteiro ML,Teixeira Vde P,Miranda Corrêa RR

更新日期：2014-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00

abstract：:The study aimed to determine the suitability of testing the saliva of kickboxing athletes to show changes in biochemical parameters in dynamic of training. 8 elite male athletes (mean age 17.29± 0.31 years, body mass 66.82± 3.46kg, with 5.62±0.96 years of training experience) participated in the study. Indicators of l...

journal_title：BioMed research international

authors： Volodchenko OA,Podrigalo LV,Iermakov SS,Żychowska MT,Jagiełło W

更新日期：2019-01-10 00:00:00

abstract：:There has been a remarkable interest in finding lipid inhibitors from natural products to replace synthetic compounds, and a variety of oriental medicinal herbs are reported to have biological activity with regard to lipid inhibition. Buginawa (Bugi) is a novel combined formula that contains twelve medicinal herbs wit...

journal_title：BioMed research international

authors： Park YJ,Seo DW,Ju JY,Cha YY,An HJ

更新日期：2019-07-30 00:00:00

abstract：:Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an i...

journal_title：BioMed research international

authors： Rahal A,Kumar A,Singh V,Yadav B,Tiwari R,Chakraborty S,Dhama K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:An increased prevalence of metabolic syndrome including nonalcoholic fatty liver disease (NAFLD) was reported in psoriasis. NAFLD can progress to nonalcoholic steatohepatitis and fibrosis. Transient elastography (TE) is a noninvasive liver fibrosis assessment. We evaluated the prevalence of significant liver...

journal_title：BioMed research international

authors： Pongpit J,Porntharukchareon S,Kaewduang P,Promson K,Stitchantrakul W,Petraksa S,Thakkinstian A,Kositchaiwat C,Rajatanavin N,Sobhonslidsuk A

更新日期：2016-01-01 00:00:00

abstract：:This study was undertaken to evaluate the effect of 3D printed polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) scaffold containing bone demineralized and decellularized extracellular matrix (bdECM) and human recombinant bone morphogenetic protein-2 (rhBMP-2) on bone regeneration. Scaffolds were divided into PCL/...

journal_title：BioMed research international

authors： Bae EB,Park KH,Shim JH,Chung HY,Choi JW,Lee JJ,Kim CH,Jeon HJ,Kang SS,Huh JB

更新日期：2018-02-27 00:00:00

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00

abstract：:Surgical flaps are frequently affected by ischemia/reperfusion (I/R) injury. Calcium-sensing receptor (CaSR) and stromal cell-derived factor-1α (SDF-1α) are closely associated with myocardial I/R injury. This study was performed to evaluate the feasibility of applying SDF-1α to counteract CaSR activation-mediated I/R ...

journal_title：BioMed research international

authors： Song L,Gao LN,Wang J,Thapa S,Li Y,Zhong XB,Zhao HW,Xiang XR,Zhang FG,Ji P

更新日期：2018-01-11 00:00:00

abstract：Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...

journal_title：BioMed research international

authors： Nie H,Hu Y,Guo W,Wang W,Yang Q,Dong Q,Tang Y,Li Q,Tang Z

更新日期：2020-06-07 00:00:00

abstract：:The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no suppleme...

journal_title：BioMed research international

authors： Siriussawakul A,Triyasunant N,Nimmannit A,Ngerncham S,Hirunkanokpan P,Luang-Aram S,Pechpaisit N,Wangdee A,Ruangvutilert P

更新日期：2014-01-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) based on the ferritin heavy chain 1 (FTH1) reporter gene has been used to trace stem cells. However, whether FTH1 expression is affected by stem cell differentiation or whether cell differentiation is affected by reporter gene expression remains unclear. Here, we explore the relationsh...

journal_title：BioMed research international

authors： Mu T,Qin Y,Liu B,He X,Liao Y,Sun J,Qiu J,Li X,Zhong Y,Cai J

更新日期：2018-06-26 00:00:00

abstract：Background:Salinity is one of the major abiotic constraints that hinder health and quality of crops. Conversely, halotolerant plant growth-promoting rhizospheric (PGPR) bacteria are considered biologically safe for alleviating salinity stress. Results:We isolated halotolerant PGPR strains from the rhizospheric soil of...

journal_title：BioMed research international

authors： Khan MA,Asaf S,Khan AL,Adhikari A,Jan R,Ali S,Imran M,Kim KM,Lee IJ

更新日期：2019-10-20 00:00:00

abstract：:Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs are bound to conforma...

journal_title：BioMed research international

authors： Hu WG,Yin J,Chau D,Hu CC,Lillico D,Yu J,Negrych LM,Cherwonogrodzky JW

更新日期：2013-01-01 00:00:00