Abstract:
:Mucosal immunity consists of innate and adaptive immune responses which can be influenced by systemic immunity. Despite having been the subject of intensive studies, it is not fully elucidated what exactly occurs after HIV contact with the female genital tract mucosa. The sexual route is the main route of HIV transmission, with an increased risk of infection in women compared to men. Several characteristics of the female genital tract make it suitable for inoculation, establishment of infection, and systemic spread of the virus, which causes local changes that may favor the development of infections by other pathogens, often called sexually transmitted diseases (STDs). The relationship of these STDs with HIV infection has been widely studied. Here we review the characteristics of mucosal immunity of the female genital tract, its alterations due to HIV/AIDS, and the characteristics of coinfections between HIV/AIDS and the most prevalent STDs.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Reis Machado J,da Silva MV,Cavellani CL,dos Reis MA,Monteiro ML,Teixeira Vde P,Miranda Corrêa RRdoi
10.1155/2014/350195subject
Has Abstractpub_date
2014-01-01 00:00:00pages
350195eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
杂志文章,评审abstract::The aim was to evaluate three different biodegradable polylactic acid- (PLA-) based osteosynthesis materials (OM). These OM (BioSorb, LactoSorb, and Delta) were used in 64 patients of whom 55 (85.9%) had fractures of the zygoma, five (7.8%) in the LeFort II level, two of the frontal bone (3.1%), and two of the maxilla...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2015/621481
更新日期:2015-01-01 00:00:00
abstract::Compressive sensing (CS) offers compression of data below the Nyquist rate, making it an attractive solution in the field of medical imaging, and has been extensively used for ultrasound (US) compression and sparse recovery. In practice, CS offers a reduction in data sensing, transmission, and storage. Compressive sen...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/7861651
更新日期:2019-11-15 00:00:00
abstract::Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/818107
更新日期:2014-01-01 00:00:00
abstract:Purpose:3D nonfluoroscopic mapping systems (NMSs) are generally used in the catheter ablation (CA) of complex ventricular and atrial arrhythmias. The aim of this study was to evaluate the efficacy, safety, and long-term effect of the extended, routine use of NMSs for CA. Methods:Our study involved 1028 patients who un...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/4217076
更新日期:2019-03-10 00:00:00
abstract::This study was aimed at investigating the changes in the degree of weight support loaded on the cane and paretic-side lower limb muscle activation according to the types of cane and cane-supported gait using a weight-support feedback cane (WSFC). Eleven hemiparetic stroke patients were recruited from a local rehabilit...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9127610
更新日期:2020-09-23 00:00:00
abstract::Insecticides are still largely applied in public health to control disease vectors. In Brazil, organophosphates (OP) and pyrethroids (PY) are used against Aedes aegypti for years. Since 2009 Insect Growth Regulators (IGR) are also employed in the control of larvae. We quantified resistance to temephos (OP), deltamethr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/8603263
更新日期:2016-01-01 00:00:00
abstract:Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6425963
更新日期:2019-04-15 00:00:00
abstract::Retinoblastoma protein (pRB) interacts with E2F and other protein factors to play a pivotal role in regulating the expression of target genes that induce cell cycle arrest, apoptosis, and differentiation. pRB controls the local promoter activity and has the ability to change the structure of nucleosomes and/or chromos...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/5959721
更新日期:2016-01-01 00:00:00
abstract::We assessed the changes in the plasma Aβ, oxidative stress/antioxidants, and membrane bound enzymes in the cerebral cortex and hippocampus of Alzheimer's disease (AD) transgenic mice (Tg2576) after dietary supplementation of Omani figs fruits for 15 months along with spatial memory and learning test. AD Tg mice on con...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/546357
更新日期:2014-01-01 00:00:00
abstract::Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hy...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6817832
更新日期:2018-03-14 00:00:00
abstract::Adipose-derived stem cells (ADSCs) are an abundant cell source and provide an easy way to harvest mesenchymal stem cells, which are the focus of considerable attention in regenerative medicine. Electric fields (EF) play roles in many biological events and have been reported to promote cell proliferation, migration, an...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7134719
更新日期:2020-11-06 00:00:00
abstract:Background and Aims:Contrast-induced nephropathy (CIN) is a relatively infrequent complication after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). However, little is known about the association between cytochrome c (cyt c) and increased risk of CIN. We conducted t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9357203
更新日期:2019-01-23 00:00:00
abstract::Aim. To explore the effects of curcumin on phosphate carrier (PiC) and its role in protection against doxorubicin induced myocyte toxicity. Methods. Using H9c2 cell line, the cardiotoxic effect of doxorubicin and its mitigation by curcumin were studied. H9c2 cells were cultured with doxorubicin and/or curcumin at vari...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/1980763
更新日期:2016-01-01 00:00:00
abstract::A comparison of the superior and inferior rectus muscles was performed to determine whether they have similar structures and innervation attributable to their participation in the same type of, although antagonistic, eye movements. The study was conducted on 70 cadaveric hemiheads, and the anatomical variations in the...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9037693
更新日期:2020-04-30 00:00:00
abstract::Bone loss and fractures may call for the use of bone substituting materials, such as calcium phosphate cements (CPCs). CPCs can be degradable, and, to determine their limitations in terms of applications, their mechanical as well as chemical properties need to be evaluated over longer periods of time, under physiologi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/575079
更新日期:2015-01-01 00:00:00
abstract:Background:Reduced baroreflex sensitivity (BRS) has been reported in patients with acute cardiovascular events. We tested the hypothesis that BRS varies in different subtypes of acute ischemic stroke (AIS) and that BRS is a predictor of clinical outcomes. Methods:We examined autonomic parameters in 34 patients with AI...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7614828
更新日期:2019-04-18 00:00:00
abstract::In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/327470
更新日期:2015-01-01 00:00:00
abstract:Aims:To investigate demographics and socioeconomic status in patients with ulnar nerve compression and the influence of socioeconomic factors on patient-reported outcome measurements (PROM) as evaluated by QuickDASH (short version of Disabilities of Arm, Shoulder and Hand) after surgery for ulnar nerve compression at t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5928649
更新日期:2020-12-18 00:00:00
abstract::Bitterness is an important taste sensation for chickens, which provides useful sensory information for acquisition and selection of diet, and warns them against ingestion of potentially harmful and noxious substances in nature. Bitter taste receptors (T2Rs) mediate the recognition of bitter compounds belonging to a fa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6301915
更新日期:2019-10-31 00:00:00
abstract::Adult orthodontics may confront problems related to the bonding performance of orthodontic brackets to new generation restorative materials used for crown or laminate restorations. The aim of the present study was to investigate the shear bond strength of ceramic brackets to two new generation CAD/CAM interpenetrating...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1871598
更新日期:2018-05-30 00:00:00
abstract::Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/403120
更新日期:2014-01-01 00:00:00
abstract:Objective:The underlying mechanisms by which cystatin C affects cardiovascular disease (CVD) are not very clear. Metabolic syndrome (MetS) is a cluster of risk factors that increase the risk of CVD. Here, we aimed to investigate the association of cystatin C with metabolic syndrome and cardiovascular outcomes in non-ST...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8541402
更新日期:2019-06-16 00:00:00
abstract::Heteronemin is a bioactive marine sesterterpene isolated from the sponge Hyrtios sp. Previous reports have shown that heteronemin possesses anticancer activity. Here, heteronemin displayed cytotoxic effects against three human cancer cell lines (A549, ACHN, and A498) and exhibited potent activity in A498 human renal c...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/738241
更新日期:2015-01-01 00:00:00
abstract::The objective of this study is to introduce a method using a percutaneous full-endoscopic interlaminar approach via a surrounding nerve root discectomy (SNRD) operative route that involves removing the protrusive disc via both the shoulder and the axilla of the corresponding nerve root for the treatment of ventral-typ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/9157089
更新日期:2018-02-12 00:00:00
abstract:Background:Oxidative stress is an important factor during age-related cataract formation. Apoptosis and autophagy induced by oxidative stress have been reported as key factors in age-related cataract. In our research, we investigated the role of let-7c-3p in the regulation of autophagy and apoptosis during the formatio...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6069390
更新日期:2020-03-16 00:00:00
abstract::Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternatives for blocking th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8680935
更新日期:2019-04-14 00:00:00
abstract::The purpose of this study was to establish an acid-etching procedure for altering the Ca/P ratio of the nanostructured surface of hydroxyapatite (HAP) by using surface chemical and morphological analyses (XPS, XRD, SEM, surface roughness, and wettability) and to evaluate the in vitro response of osteoblast-like cells ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/626452
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:Inflammation in dental pulp cells (DPCs) initiated by Lipopolysaccharide (LPS) results in dental pulp necrosis. So far, whether there is a common system regulating inflammation response and tissue regeneration remains unknown. miR-146a is closely related to inflammation. Basic fibroblast growth factor (bFG...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3892685
更新日期:2016-01-01 00:00:00
abstract:Background:Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. Methods:Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the hepatocellular apoptosi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2953068
更新日期:2020-03-18 00:00:00
abstract::Tumourigenesis is a mutation accumulation process, which is likely to start with a mutated founder cell. The evolutionary nature of tumor development makes phylogenetic models suitable for inferring tumor evolution through genetic variation data. Copy number variation (CNV) is the major genetic marker of the genome wi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/5482750
更新日期:2017-01-01 00:00:00