Effect of miR-146a/bFGF/PEG-PEI Nanoparticles on Inflammation Response and Tissue Regeneration of Human Dental Pulp Cells.

abstract：:WHO reported that adherence among patients with chronic diseases averages only 50% in developed countries. This is recognized as a significant public health issue, since medication nonadherence leads to poor health outcomes and increased healthcare costs. Improving medication adherence is, therefore, crucial and revea...

journal_title：BioMed research international

authors： Lam WY,Fresco P

更新日期：2015-01-01 00:00:00

abstract：:The valorization of Crocus sativus L. by-products has become important given its interesting content of bioactive molecules. In the present study, aqueous tepal extract (ATE) studied eggplant seedling's growth and physiology under a plastic tunnel. ATE was foliage sprayed 3 times every 15 days, with various concentrat...

journal_title：BioMed research international

authors： Khoulati A,Ouahhoud S,Mamri S,Meziane M,Choukri M,Asehraou A,Saalaoui E

更新日期：2020-11-05 00:00:00

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：:Technetium-99 conjugated with methylene diphosphonate (99Tc-MDP) is an effective anti-inflammatory drug in treating rheumatoid arthritis (RA) for over 15 years in China. However, as a special form of bisphosphonate, the antiosteoporotic effect of 99Tc-MDP is unclear. We systematically investigated the effects of 99Tc-...

journal_title：BioMed research international

authors： Shi L,Ning Y,Xu L,Li J,Zhang X

更新日期：2018-10-14 00:00:00

abstract：:To study the effect of intra-abdominal hypertension (IAH) on the frequency of pneumonia with an experimental study, thirteen Sprague-Dawley rats were included. Eight out of thirteen animals were randomly assigned to receive 10 ml of benzalkonium chloride 0.2% (megacolon group) and five animals received 10 ml NaCl 0.9%...

journal_title：BioMed research international

authors： Papakrivou E,Makris D,Manoulakas E,Mitroudi M,Tepetes K,Papazoglou K,Zakynthinos E

更新日期：2017-01-01 00:00:00

abstract：:Hepatic fibrosis is a leading cause of morbidity and mortality worldwide. Hepatic fibrosis is usually associated with chronic liver diseases caused by infection, drugs, metabolic disorders, or autoimmune imbalances. Effective clinical therapies are still lacking. Autophagy is a cellular process that degrades damaged o...

journal_title：BioMed research international

authors： Song Y,Zhao Y,Wang F,Tao L,Xiao J,Yang C

更新日期：2014-01-01 00:00:00

abstract：:We investigated (a) if activation of the mitogen activated protein kinase (MAPK) pathway was linked to the stress activated protein kinase (SAPK) pathway and (b) if JNK was required for activation of c-Jun in Schwann cells of rat sciatic nerve following injury. To this aim, ERK1/2 and the transcription factors c-Jun a...

journal_title：BioMed research international

authors： Blom CL,Mårtensson LB,Dahlin LB

更新日期：2014-01-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) has several functions in the central nervous system, where it contributes to brain development and its functionality through affecting neuronal survival and activity and also modulating neurotransmitter levels. This neurotrophin is also found in the serum, but its origin and pe...

journal_title：BioMed research international

authors： Türck P,Frizzo ME

更新日期：2015-01-01 00:00:00

abstract：:The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

journal_title：BioMed research international

authors： Guevara L,Antolinos V,Palop A,Periago PM

更新日期：2015-01-01 00:00:00

abstract：:As a major tumor suppressor gene, the role of PinX1 in breast cancer and its molecular mechanism remain unclear. In this study, overexpression of PinX1 was generated in 3 breast cancer cell lines, and knockdown of PinX1 was performed in a nontumorigenic breast cell line. The regulation of PinX1 on cell proliferation a...

journal_title：BioMed research international

authors： Shi R,Zhou JY,Zhou H,Zhao Z,Liang SH,Zheng WL,Ma WL

更新日期：2014-01-01 00:00:00

abstract：:This study aimed to examine the expression of and the relationship between CD44V6, CDH11, and β-catenin. The expression of these cell adhesion molecules was detected in 90 osteosarcoma and 20 osteochondroma specimens using immunohistochemistry. Associations between these parameters and clinicopathological data were al...

journal_title：BioMed research international

authors： Deng Z,Niu G,Cai L,Wei R,Zhao X

更新日期：2013-01-01 00:00:00

abstract：:The large-scale production of cardiomyocytes is a key step in the development of cell therapy and tissue engineering to treat cardiovascular diseases, particularly those caused by ischemia. The main objective of this study was to establish a procedure for the efficient production of cardiomyocytes by reprogramming mes...

journal_title：BioMed research international

authors： Zanetti BF,Gomes WJ,Han SW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：:Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel indicator for diagnosis of diabetic kidney disease (DKD). The aim of this study was to investigate the possibility of serum HE4 as a novel biomarker for DKD in patients...

journal_title：BioMed research international

authors： Zhang M,Zhao B,Xie J,Liang Y,Yang Z

更新日期：2019-11-11 00:00:00

abstract：:Myocardial ischemia-reperfusion (I/R) injury is experienced by individuals suffering from cardiovascular diseases such as coronary heart diseases and subsequently undergoing reperfusion treatments in order to manage the conditions. The occlusion of blood flow to the tissue, termed ischemia, can be especially detriment...

journal_title：BioMed research international

authors： Zhou T,Chuang CC,Zuo L

更新日期：2015-01-01 00:00:00

abstract：:Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

journal_title：BioMed research international

authors： Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

更新日期：2016-01-01 00:00:00

abstract：Objective:The NOCTURNIN gene links nutrient absorption and metabolism to the circadian clock. Shift workers are at a heightened risk of overweight and of developing obesity and metabolic syndrome. This study investigates the diurnal variation of NOCTURNIN in healthy volunteers and its expression levels in rotational sh...

journal_title：BioMed research international

authors： Bracci M,Copertaro A,Ciarapica V,Barbaresi M,Esposito S,Albanesi A,Valentino M,Ledda C,Rapisarda V,Santarelli L

更新日期：2019-07-31 00:00:00

abstract：:The development of multitargeting drugs is an emerging trend in cancer research. To promote further development and clinical application of multitargeting drugs, this research was performed. MTT assay and flow cytometry of Annexin V/propidium iodide staining were used to confirm the proapoptotic efficacy of a novel co...

journal_title：BioMed research international

authors： Zheng H,Liang G,Chen Y,Lin S,Liu W,Fang Y

更新日期：2017-01-01 00:00:00

abstract：:Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement....

journal_title：BioMed research international

authors： Nisticò S,Campolmi P,Moretti S,Del Duca E,Bruscino N,Conti R,Bassi A,Cannarozzo G

更新日期：2016-01-01 00:00:00

abstract：:The use of modern surgical dressings to prevent wound complications and surgical site infection (SSI) after minimally invasive total knee arthroplasty (MIS-TKA) is lacking. In a prospective, randomized, controlled study, 240 patients were randomized to receive either AQUACEL Ag Surgical dressing (study group) or a sta...

journal_title：BioMed research international

authors： Kuo FC,Chen B,Lee MS,Yen SH,Wang JW

更新日期：2017-01-01 00:00:00

abstract：Aim:The aim of this study was to explore the correlation of chemokine receptor CXCR3 with M2 macrophage infiltration, various clinicopathological features, and prognosis in patients diagnosed with gastric cancer (GC). Methods:Expression of CXCR3 protein and M2 macrophage was evaluated in 156 GC patients and correspond...

journal_title：BioMed research international

authors： Chen F,Yuan J,Yan H,Liu H,Yin S

更新日期：2019-05-21 00:00:00

abstract：OBJECTIVES:To investigate the availability of correction of mandibular plane using software for vertical measurements in cone beam computed tomography (CBCT) according to the sites of the mandible. METHODS:CBCT scans of six dry mandibles were performed at 0-, 5-, 10-, 15-, and 20-degree angles relative to CBCT scannin...

journal_title：BioMed research international

authors： Han SS,Lee KM,Kim KD

更新日期：2015-01-01 00:00:00

abstract：:The aim of this population-based cohort study was to explore postoperative renal outcomes of patients receiving pyelolithotomy versus percutaneous nephrolithotomy (PCNL). Data were retrieved from the Taiwan National Health Insurance Research Database. During the period from Jan 1, 1998, to Dec 31, 2012, there were 254...

journal_title：BioMed research international

authors： Chen FT,Liu FC,Cheng CW,Lin JR,Yu HP

更新日期：2018-05-02 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:The purpose of this paper is to examine how well the human induced pluripotent stem cell (hiPSC) colony images can be classified using error-correcting output codes (ECOC). Our image dataset includes hiPSC colony images from three classes (bad, semigood, and good) which makes our classification task a multiclass probl...

journal_title：BioMed research international

authors： Joutsijoki H,Haponen M,Rasku J,Aalto-Setälä K,Juhola M

更新日期：2016-01-01 00:00:00

abstract：Objectives:Obstructive sleep apnea (OSA) is a common disorder influenced by genetic and environmental factors. Mutations of AT-hook DNA-binding motif containing 1 (AHDC1) gene have been implicated which could cause rare syndromes presenting OSA. This study aims to investigate some rare mutations of AHDC1 in Chinese Han...

journal_title：BioMed research international

authors： Yang S,Li K,Zhu MM,Yuan XD,Jiao XL,Yang YY,Li J,Li L,Zhang HN,Du YH,Wei YX,Qin YW

更新日期：2019-10-13 00:00:00

abstract：:We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with glass tubes in Chouckroun's leukocyte- and platelet-rich fibrin (L-PRF) method. In this study, w...

journal_title：BioMed research international

authors： Tunalı M,Özdemir H,Küçükodacı Z,Akman S,Yaprak E,Toker H,Fıratlı E

更新日期：2014-01-01 00:00:00

abstract：:Background. Genome-wide association studies (GWAS) have shown its revolutionary power in seeking the influenced loci on complex diseases genetically. Thousands of replicated loci for common traits are helpful in diseases risk assessment. However it is still difficult to elucidate the variations in these loci that dire...

journal_title：BioMed research international

authors： Ma LX,Wang YJ,Wang JF,Li X,Hao P

更新日期：2013-01-01 00:00:00

abstract：:A Chinese medicinal fern Blechnum orientale (Linn) was separately collected from polluted and unpolluted sites to determine whether it could accumulate hazardous pollutants or not. Metal concentrations (Cu, Zn, Mn, Pb, Cd, Cr, As, and Hg) both in the fronds and roots and polycyclic aromatic hydrocarbons (PAHs) in the ...

journal_title：BioMed research international

authors： Zhu XM,Kuang YW,Xi D,Li J,Wang FG

更新日期：2013-01-01 00:00:00