miR-331-3p Inhibits Inflammatory Response after Intracerebral Hemorrhage by Directly Targeting NLRP6.

abstract：Objectives:Percutaneous coronary intervention (PCI) is the mainstay treatment for coronary artery disease but complications such as in-stent restenosis and thrombosis remain problematic. Radiofrequency balloon angioplasty (RBA) can improve lumen dimension, fusing intimal tears, and artery dissection but is associated w...

journal_title：BioMed research international

authors： Chen Q,Wang M,Shao S,Liu H,Xia X,Tse G,Yuan M,Zhang Y,Liang X,Liu T,Li G

更新日期：2018-12-23 00:00:00

abstract：:Metabolic syndrome (MetS) is a steering force for the cardiovascular diseases epidemic in Asia. This study aimed to compare the prevalence of MetS in Malaysian adults using NCEP-ATP III, IDF, and JIS definitions, identify the demographic factors associated with MetS, and determine the level of agreement between these ...

journal_title：BioMed research international

authors： Ramli AS,Daher AM,Nor-Ashikin MN,Mat-Nasir N,Ng KK,Miskan M,Ambigga KS,Ariffin F,Mazapuspavina MY,Abdul-Razak S,Abdul-Hamid H,Abd-Majid F,Abu-Bakar N,Nawawi H,Yusoff K

更新日期：2013-01-01 00:00:00

abstract：Background:This study investigated the potential therapeutic effects of acupoint catgut embedding (ACE) at ST36 and BL13 on lipopolysaccharide- (LPS-) induced acute respiratory distress syndrome (ARDS) in rats. Materials and Methods:Male Sprague-Dawley rats were randomized into the normal saline (NS group with a sham ...

journal_title：BioMed research international

authors： Li D,Sun T,Chi L,Zhao D,Li W

更新日期：2020-05-02 00:00:00

abstract：Objective:To analyse the short-term adverse effects (AEs) of propranolol in the treatment of infantile hemangiomas (IHs) and their relevant factors, as well as the relationship between child growth and propranolol. Methods:A total of 506 patients with confirmed or suspected IHs were enrolled, and a total of 439 cases ...

journal_title：BioMed research international

authors： Li X,Yang K,Li H,Huo R

更新日期：2019-11-25 00:00:00

abstract：:There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...

journal_title：BioMed research international

authors： Paldino E,Tesori V,Casalbore P,Gasbarrini A,Puglisi MA

更新日期：2014-01-01 00:00:00

abstract：Background and Aims:The value of hepatocyte regeneration in predicting the outcomes of hepatitis B-related acute-on-chronic liver failure (HBV-ACLF) is not fully assessed. The present study was aimed at establishing a novel scoring system to predict patients' outcomes within 3 months by applying serological indicators ...

journal_title：BioMed research international

authors： Wang X,Sun M,Yang X,Gao L,Weng M,Yang D,Li H,Zhou X,Li J,Qin S,Zhou D,Wu X,Tang S,Zeng W

更新日期：2020-08-06 00:00:00

abstract：:A familiarity with the anatomy of some types of bone anomalies is necessary for clinicians involved in many medical areas. The aim of this paper is to review the newest literature concerning the morphology, embryology, clinical image, and therapeutic methods of the cervical ribs in the humans. The incidence of cervica...

journal_title：BioMed research international

authors： Spadliński Ł,Cecot T,Majos A,Stefańczyk L,Pietruszewska W,Wysiadecki G,Topol M,Polguj M

更新日期：2016-01-01 00:00:00

abstract：:The role of factor XIII subunit A (FXIII-A) is not restricted to hemostasis. FXIII-A is also present intracellularly in several human cells and serves as a diagnostic marker in a wide range of dermatological diseases from inflammatory conditions to malignancies. In this review, we provide a guide on the still controve...

journal_title：BioMed research international

authors： Paragh L,Törőcsik D

更新日期：2017-01-01 00:00:00

abstract：:This study included 30 patients with diagnosed rheumatoid arthritis (RA) and 30 test subjects without RA (control group). The objective of the study was to examine both groups for the presence of temporomandibular disorders (TMD) and morphological changes of the temporomandibular joint (TMJ). All individuals were exam...

journal_title：BioMed research international

authors： Witulski S,Vogl TJ,Rehart S,Ottl P

更新日期：2014-01-01 00:00:00

abstract：:RAW264.7 is a macrophage strain derived from mice tumour and shows a significant ability in antigen uptake. Real-time quantitative PCR (RT-qPCR) is one of the most commonly used methods in gene studies and requires suitable reference genes to normalize and quantitate the expression of gene of interest with sensitivity...

journal_title：BioMed research international

authors： Bao Z,Huang Y,Chen J,Wang Z,Qian J,Xu J,Zhao Y

更新日期：2019-05-16 00:00:00

abstract：:This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...

journal_title：BioMed research international

authors： Abdel Aziz MT,Khaled HM,El Hindawi A,Roshdy NK,Rashed LA,Sabry D,Hassouna AA,Taha F,Ali WI

更新日期：2013-01-01 00:00:00

abstract：:Background. The survival rates of in-hospital cardiac arrests (IHCAs) are reportedly low at night, but the difference between the survival rates of cardiac origin and noncardiac origin IHCAs occurring at night remains unclear. Methods. Outcomes of IHCAs during different shifts (night, day, and evening) were compared a...

journal_title：BioMed research international

authors： Syue YJ,Huang JB,Cheng FJ,Kung CT,Li CJ

更新日期：2016-01-01 00:00:00

abstract：:Finding an optimal set of discriminative features is still a crucial but challenging task in biomedical science. The complexity of the task is intensified when any of the two scenarios arise: a highly dimensioned dataset and a small sample-sized dataset. The first scenario poses a big challenge to existing machine lea...

journal_title：BioMed research international

authors： Segera D,Mbuthia M,Nyete A

更新日期：2020-08-17 00:00:00

abstract：:Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...

journal_title：BioMed research international

authors： Yang J,Zhao CZ,Chen B,Chen F,Han J,Hu SJ

更新日期：2015-01-01 00:00:00

abstract：:GABAergic inhibition and particularly perisomatic inhibition play a crucial role in controlling the firing properties of large principal cell populations. Furthermore, GABAergic network is a key element in the therapy attempting to reduce epileptic activity. Here, we present a review showing the synaptic changes of pe...

journal_title：BioMed research international

authors： Wittner L,Maglóczky Z

更新日期：2017-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00

abstract：:Cardiogenic shock (CS) is uncommon in patients suffering from acute myocardial infarction (AMI). Long-term outcome and adverse predictors for outcomes in AMI patients with CS receiving percutaneous coronary interventions (PCI) are unclear. A total of 482 AMI patients who received PCI were collected, including 53 CS an...

journal_title：BioMed research international

authors： Lin MJ,Chen CY,Lin HD,Wu HP

更新日期：2017-01-01 00:00:00

abstract：UNLABELLED:H. pylori is related to various gastrointestinal diseases. β₂ Microglobulin (β 2M) is an intrinsic element of major histocompatibility complex (MHC I). Serum β₂M level may increase in inflammatory states. The aim of current study is to evaluate the relationship between β₂M and H. pylori bearing CagA strains....

journal_title：BioMed research international

authors： Yeniova AÖ,Kucukazman M,Ata N,Dal K,Kefeli A,Başyiğit S,Aktaş B,Akın KO,Nazlıgül Y

更新日期：2014-01-01 00:00:00

abstract：:Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous antagonist, has been im...

journal_title：BioMed research international

authors： He T,Zhao L,Zhang D,Zhang Q,Jia J,Hu J,Huang Y

更新日期：2015-01-01 00:00:00

abstract：:We review the recent literature concerning the efficiency of antimicrobial photodynamic inactivation toward various microbial species in planktonic and biofilm cultures. The review is mainly focused on biofilm-growing microrganisms because this form of growth poses a threat to chronically infected or immunocompromised...

journal_title：BioMed research international

authors： Taraszkiewicz A,Fila G,Grinholc M,Nakonieczna J

更新日期：2013-01-01 00:00:00

abstract：:The release of ATP from the urothelium in response to stretch during filling demonstrates the importance of the purinergic system for the physiological functioning of the bladder. This study examined the effect of P2 receptor agonists on ATP release from two urothelial cell lines (RT4 and UROtsa cells). Hypotonic Kreb...

journal_title：BioMed research international

authors： Mansfield KJ,Hughes JR

更新日期：2014-01-01 00:00:00

abstract：:Cigarette smoke is highly toxic, and it can promote increased production of reactive species and inflammatory response and leads to liver diseases. Quercetin is a flavonoid that displays antioxidant and anti-inflammatory activities in liver diseases. This study aimed at evaluating the protective effects of quercetin o...

journal_title：BioMed research international

authors： Machado-Junior PA,Araújo NPS,Souza ABF,Castro TF,Oliveira M,Costa GP,Matos NA,Vieira PMA,Talvani A,Bezerra FS,Cangussú SD

更新日期：2020-11-15 00:00:00

abstract：:There were no systematic researches about autophagy-related long noncoding RNA (lncRNA) signatures to predict the survival of patients with colon adenocarcinoma. It was necessary to set up corresponding autophagy-related lncRNA signatures. The expression profiles of lncRNAs which contained 480 colon adenocarcinoma sam...

journal_title：BioMed research international

authors： Zhou W,Zhang S,Li HB,Cai Z,Tang S,Chen LX,Lang JY,Chen Z,Chen XL

更新日期：2020-09-02 00:00:00

abstract：:Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole...

journal_title：BioMed research international

authors： Butkutė B,Dagilytė A,Benetis R,Padarauskas A,Cesevičienė J,Olšauskaitė V,Lemežienė N

更新日期：2018-01-21 00:00:00

abstract：:Tobacco smoking continues to be a leading cause of disease and mortality. Recent research has confirmed the important role of nicotinic acetylcholine receptor (nAChR) gene cluster on chromosome 15q 24-25 in nicotine dependence and smoking. In this study we tested the association of smoking initiation, age at onset of ...

journal_title：BioMed research international

authors： Buczkowski K,Sieminska A,Linkowska K,Czachowski S,Przybylski G,Jassem E,Grzybowski T

更新日期：2015-01-01 00:00:00

abstract：:Chagas disease is caused by Trypanosoma cruzi infection. Besides the host-related factors, such as immune response and genetic background, the parasite, strain, and occurrences of reinfection episodes, may influence disease outcome. Our results demonstrate that both the primary infection and the reinfection with the C...

journal_title：BioMed research international

authors： Reis Machado J,Silva MV,Borges DC,da Silva CA,Ramirez LE,dos Reis MA,Castellano LR,Rodrigues V,Rodrigues DB

更新日期：2014-01-01 00:00:00

abstract：:Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to kee...

journal_title：BioMed research international

authors： Friedrich A,Kenar E,Kohlbacher O,Nahnsen S

更新日期：2015-01-01 00:00:00

abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

journal_title：BioMed research international

authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

更新日期：2014-01-01 00:00:00

abstract：:Toxoplasma gondii with worldwide distribution has received substantial medical and scientific attentions as it causes serious clinical and veterinary problems especially for pregnant women and immunocompromised patients. Heat shock protein 40 (HSP40) plays a variety of essential roles in the pathogenesis of this proto...

journal_title：BioMed research international

authors： Li ZY,Lu J,Zhou DH,Chen J,Zhu XQ

更新日期：2015-01-01 00:00:00

abstract：:Acute nonspecific, or primary, mesenteric lymphadenitis is a self-limiting inflammatory condition affecting the mesenteric lymph nodes, whose presentation mimics appendicitis or intussusception. It typically occurs in children, adolescents, and young adults. White blood count and C-reactive protein are of limited usef...

journal_title：BioMed research international

authors： Helbling R,Conficconi E,Wyttenbach M,Benetti C,Simonetti GD,Bianchetti MG,Hamitaga F,Lava SA,Fossali EF,Milani GP

更新日期：2017-01-01 00:00:00