Genetic Polymorphisms of IL-17F and TRAF3IP2 Could Be Predictive Factors of the Long-Term Effect of Infliximab against Crohn's Disease.

abstract：:The use of modern surgical dressings to prevent wound complications and surgical site infection (SSI) after minimally invasive total knee arthroplasty (MIS-TKA) is lacking. In a prospective, randomized, controlled study, 240 patients were randomized to receive either AQUACEL Ag Surgical dressing (study group) or a sta...

journal_title：BioMed research international

authors： Kuo FC,Chen B,Lee MS,Yen SH,Wang JW

更新日期：2017-01-01 00:00:00

abstract：:Radiation pneumonitis (RP) is a common complication for radiotherapy of esophageal cancer and is associated with the low dose irradiated lung volume. This study aims to reduce the mean lung dose (MLD) and the relative lung volume at 20 Gy (V 20) and at low dose region using various designs of the fan-shaped complete b...

journal_title：BioMed research international

authors： Chang CH,Mok GS,Shueng PW,Yeh HP,Shiau AC,Tien HJ,Lin CT,Wu TH

更新日期：2015-01-01 00:00:00

abstract：:Integrins are a family of membrane-spanning proteins that are important receptors for cell adhesion to extracellular matrix proteins. They also provide connections between the extracellular environment and intracellular cytoskeletons and are responsible for activation of many intracellular signaling pathways. In vitro...

journal_title：BioMed research international

authors： Zhong Y,Wang J,Luo X

更新日期：2013-01-01 00:00:00

abstract：:In order to understand disease pathogenesis, improve medical diagnosis, or discover effective drug targets, it is important to identify significant genes deeply involved in human disease. For this purpose, many earlier approaches attempted to prioritize candidate genes using gene expression profiles or SNP genotype da...

journal_title：BioMed research international

authors： Che J,Shin M

更新日期：2015-01-01 00:00:00

abstract：:Anopheles gambiae is the major malaria vector in Africa. Examining the molecular basis of A. gambiae traits requires knowledge of both genetic variation and genome-wide linkage disequilibrium (LD) map of wild A. gambiae populations from malaria-endemic areas. We sequenced the genomes of nine wild A. gambiae mosquitoes...

journal_title：BioMed research international

authors： Wang X,Afrane YA,Yan G,Li J

更新日期：2015-01-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most prevalent form of oral cancer. Inducible nitric oxide synthase (iNOS) and p53 are associated with a variety of human cancers, but their expression and interaction in OSCC have not been fully explored. In this study, we investigated the expression of iNOS and p53 in OSCC ...

journal_title：BioMed research international

authors： Yang L,Wang Y,Guo L,Wang L,Chen W,Shi B

更新日期：2015-01-01 00:00:00

abstract：:In the present study, the biobleaching potential of white rot fungus Cordyceps militaris MTCC3936 was investigated. For preliminary screening, decolorization properties of C. militaris were comparatively studied using whole cells in agar-based and liquid culture systems. Preliminary investigation in liquid culture sys...

journal_title：BioMed research international

authors： Kaur B,Kumar B,Garg N,Kaur N

更新日期：2015-01-01 00:00:00

abstract：:Despite many advances in the diagnosis and treatment of colorectal cancer (CRC), its incidence and mortality rates continue to make an impact worldwide and in some countries rates are mounting. Over the past decade, liquid biopsies have been the object of fundamental and clinical research with regard to the different ...

journal_title：BioMed research international

authors： Christou N,Meyer J,Popeskou S,David V,Toso C,Buchs N,Liot E,Robert J,Ris F,Mathonnet M

更新日期：2019-12-04 00:00:00

abstract：:We performed a retrospective review of 40 consecutive modern cementless THAs with 65-month mean followup in 34 patients under the age of 30 primarily for diagnoses other than inflammatory arthritis. We found acceptable functional improvement and radiographic outcomes at mean 5-year followup. We found a high transfusio...

journal_title：BioMed research international

authors： Gililland JM,Anderson LA,Erickson J,Pelt CE,Peters CL

更新日期：2013-01-01 00:00:00

abstract：:Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...

journal_title：BioMed research international

authors： Jha A,Flurchick KM,Bikdash M,Kc DB

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome can be caused by modification of diet by means of consumption of high carbohydrate and high fat diet such as fructose. AIMS:To develop a metabolic syndrome rat model by induction of fructose drinking water (FDW) in male Wistar rats. METHODS:Eighteen male Wistar rats were fed with FDW 20%...

journal_title：BioMed research international

authors： Mamikutty N,Thent ZC,Sapri SR,Sahruddin NN,Mohd Yusof MR,Haji Suhaimi F

更新日期：2014-01-01 00:00:00

abstract：:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia f...

journal_title：BioMed research international

authors： Haufe T,Förch S,Müller P,Plath J,Mayr E

更新日期：2016-01-01 00:00:00

abstract：:Acute nonspecific, or primary, mesenteric lymphadenitis is a self-limiting inflammatory condition affecting the mesenteric lymph nodes, whose presentation mimics appendicitis or intussusception. It typically occurs in children, adolescents, and young adults. White blood count and C-reactive protein are of limited usef...

journal_title：BioMed research international

authors： Helbling R,Conficconi E,Wyttenbach M,Benetti C,Simonetti GD,Bianchetti MG,Hamitaga F,Lava SA,Fossali EF,Milani GP

更新日期：2017-01-01 00:00:00

abstract：:GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine but declines with age. It is proposed that GHK functions as a complex with copper 2+ which accelerates wound healing and skin repair. GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity ...

journal_title：BioMed research international

authors： Pickart L,Vasquez-Soltero JM,Margolina A

更新日期：2015-01-01 00:00:00

abstract：:The current developments of the new biological drugs targeting interleukin 5 (IL-5) and IL-5 receptor allowed to expand the treatment options for severe hypereosinophilic asthma. Clinicians will then be able to choose between antibodies targeting either circulating IL-5 or its receptor expressed on eosinophils and bas...

journal_title：BioMed research international

authors： Bagnasco D,Caminati M,Ferrando M,Aloè T,Testino E,Canonica GW,Passalacqua G

更新日期：2018-11-05 00:00:00

abstract：:Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...

journal_title：BioMed research international

authors： Bit A,Ghagare D,Rizvanov AA,Chattopadhyay H

更新日期：2017-01-01 00:00:00

abstract：:Multiparametric MRI of the prostate combines high-resolution anatomic imaging with functional imaging of alterations in normal tissue caused by neoplastic transformation for the identification and characterization of in situ prostate cancer. Lesion detection relies on a systematic approach to the analysis of both anat...

journal_title：BioMed research international

authors： Margolis DJ

更新日期：2014-01-01 00:00:00

abstract：Background:Fibroid is the most common benign tumor of the uterus and if associated with pregnancy may adversely affect the outcome of pregnancy. Objective of the present study was to assess the obstetric outcome (maternal and fetal) in pregnancy with fibroid. Methods:A prospective observational study was performed ove...

journal_title：BioMed research international

authors： Saleh HS,Mowafy HE,Hameid AAAE,Sherif HE,Mahfouz EM

更新日期：2018-03-26 00:00:00

abstract：PURPOSE OF THE REPORT:There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role of (99m)Tc-ECD SPECT in a large number of subjects with craniosynostosis. MATERIALS AND METHODS:We prospectively analyzed a coh...

journal_title：BioMed research international

authors： Barik M,Bajpai M,Das RR,Malhotra A,Panda SS,Sahoo MK,Dwivedi S

更新日期：2014-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a lethal malignancy with poor prognosis and limited treatment options. Transarterial chemoembolization (TACE) using chemotherapy agents-doxorubicin and cisplatin-is an accepted treatment option for locally advanced hepatocellular carcinoma. In the current study, we analyzed the expres...

journal_title：BioMed research international

authors： El-Halawany MS,Ismail HM,Zeeneldin AA,Elfiky A,Tantawy M,Kobaisi MH,Hamed I,Abdel Wahab AH

更新日期：2015-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) and lung cancer, closely related to smoking, are major lung diseases affecting millions of individuals worldwide. The generated gas mixture of smoking is proved to contain about 4,500 components such as carbon monoxide, nicotine, oxidants, fine particulate matter, and aldeh...

journal_title：BioMed research international

authors： Hou W,Hu S,Li C,Ma H,Wang Q,Meng G,Guo T,Zhang J

更新日期：2019-06-24 00:00:00

abstract：:Alpha-linolenic acid (ALA) is plant-based essential omega-3 polyunsaturated fatty acids that must be obtained through the diet. This could explain in part why the severe deficiency in omega-3 intake pointed by numerous epidemiologic studies may increase the brain's vulnerability representing an important risk factor i...

journal_title：BioMed research international

authors： Blondeau N,Lipsky RH,Bourourou M,Duncan MW,Gorelick PB,Marini AM

更新日期：2015-01-01 00:00:00

abstract：:Uveitic glaucoma (UG) typically is associated with very high intraocular pressure (IOP) and more intense optic nerve damage than other glaucoma types. This secondary glaucoma requires an early diagnosis and adequate management of both uveitis and glaucoma. It is mandatory to identify the mechanisms of IOP elevation th...

journal_title：BioMed research international

authors： Muñoz-Negrete FJ,Moreno-Montañés J,Hernández-Martínez P,Rebolleda G

更新日期：2015-01-01 00:00:00

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：:Myostatin, a TGF-β family member, is associated with inhibition of muscle growth and differentiation and might interact with the IGF-1 signaling pathway. Since IGF-1 is secreted at a bioactive level by adipose tissue-derived mesenchymal stem cells (ASCs), these cells (ASCs) provide a therapeutic option for Duchenne Mu...

journal_title：BioMed research international

authors： Gehmert S,Wenzel C,Loibl M,Brockhoff G,Huber M,Krutsch W,Nerlich M,Gosau M,Klein S,Schreml S,Prantl L,Gehmert S

更新日期：2014-01-01 00:00:00

abstract：Introduction:The incidence of acute kidney injury (AKI) considerably increases the mortality rate in polytrauma victims. Undoubtedly, early identification of patients at risk is crucial for timely implementation of preventive strategies in order to improve their prognosis. Therefore, we aimed to investigate if serum ne...

journal_title：BioMed research international

authors： Negrin LL,Hahn R,Heinz T,Hajdu S

更新日期：2018-11-06 00:00:00

abstract：:The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry criteria of probe dr...

journal_title：BioMed research international

authors： Wang L,Chiang C,Liang H,Wu H,Feng W,Quinney SK,Li J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Coronary computed tomography angiography (CCTA) has been recently evaluated for its ability to assess coronary plaque characteristics, including plaque composition. Identification of the relationship between plaque composition by CCTA and patient clinical presentations may provide insight into the pathophysiology of c...

journal_title：BioMed research international

authors： Sun Z,Xu L

更新日期：2014-01-01 00:00:00

abstract：Introduction:This study examines the utility of electroencephalography (EEG) in clinical decision making in acute ischemic stroke (AIS) patients in regards to the prescription of antiseizure medications. Methods:Patients were grouped as having positive EEG (+) for epileptiform activity or negative EEG (-). These studi...

journal_title：BioMed research international

authors： Rao R,Monlezun DJ,Kimbrough T,Burkett BJ,Samai A,Martin-Schild S

更新日期：2020-12-19 00:00:00

abstract：:The insula is believed to be associated with touch-evoked effects. In this work, functional MRI was applied to investigate the network model of insula function when 20 normal subjects received tactile stimulation over segregated areas. Data analysis was performed with SPM8 and Conn toolbox. Activations in the contrala...

journal_title：BioMed research international

authors： Wei P,Bao R

更新日期：2013-01-01 00:00:00