Investigating the pretreatment miRNA expression patterns of advanced hepatocellular carcinoma patients in association with response to TACE treatment.

abstract：:This study attempted to find novel age-related macular degeneration (AMD) related genes based on 36 known AMD genes. The well-known shortest path algorithm, Dijkstra's algorithm, was applied to find the shortest path connecting each pair of known AMD related genes in protein-protein interaction (PPI) network. The gene...

journal_title：BioMed research international

authors： Zhang J,Jiang M,Yuan F,Feng KY,Cai YD,Xu X,Chen L

更新日期：2013-01-01 00:00:00

abstract：:Brachial plexus injury often involves traumatic root avulsion resulting in permanent paralysis of the innervated muscles. The lack of sufficient regeneration from spinal motoneurons to the peripheral nerve (PN) is considered to be one of the major causes of the unsatisfactory outcome of various surgical interventions ...

journal_title：BioMed research international

authors： Su H,Yuan Q,Qin D,Yang X,Wong WM,So KF,Wu W

更新日期：2014-01-01 00:00:00

abstract：:Single-sided deafness (SSD) induces cortical neural plastic changes according to duration of deafness. However, it is still unclear how the auditory cortical changes accompany the subcortical neural changes. The present study aimed to find the neural plastic changes in the cortical and subcortical auditory system foll...

journal_title：BioMed research international

authors： Kim SY,Heo H,Kim DH,Kim HJ,Oh SH

更新日期：2018-11-26 00:00:00

abstract：:Hosts' innate defense systems are upregulated by antimicrobial peptide elicitors (APEs). Our aim was to investigate the effects of hyperthermia, ultraviolet A rays (UVA), and ultraviolet C rays (UVC) as well as glucose and ascorbic acid (AA) on the regulation of human β-defensin 1 (DEFB1), cathelicidin (CAMP), and int...

journal_title：BioMed research international

authors： Cruz Díaz LA,Flores Miramontes MG,Chávez Hurtado P,Allen K,Gonzalez Ávila M,Prado Montes de Oca E

更新日期：2015-01-01 00:00:00

abstract：:Therapeutic approach for Alzheimer's disease (AD) is still deficient. To find active compounds from herbal medicine is of interest in the alleviation of AD symptoms. This study aimed to investigate the protective effects of Tanshinone IIA (TIIA) on memory performance and synaptic plasticity in a transgenic AD model at...

journal_title：BioMed research international

authors： Li F,Han G,Wu K

更新日期：2016-01-01 00:00:00

abstract：:Liver cell culture within three-dimensional structures provides an improved culture system for various applications in basic research, pharmacological screening, and implantable or extracorporeal liver support. Biodegradable calcium-based scaffolds in such systems could enhance liver cell functionality by providing en...

journal_title：BioMed research international

authors： Finoli A,Schmelzer E,Over P,Nettleship I,Gerlach JC

更新日期：2016-01-01 00:00:00

abstract：:This work evaluated the physicochemical properties and antioxidant activity of spray dried extracts (SDE) from Psidium guajava L. leaves. Different drying carriers, namely, maltodextrin, colloidal silicon dioxide, Arabic gum, and β -cyclodextrin at concentrations of 40 and 80% relative to solids content, were added to...

journal_title：BioMed research international

authors： Fernandes MR,Azzolini AE,Martinez ML,Souza CR,Lucisano-Valim YM,Oliveira WP

更新日期：2014-01-01 00:00:00

abstract：:Studies on the occurrence of pharmaceuticals show that the widely used pharmaceuticals ibuprofen and diclofenac are present in relevant concentrations in the environment. A pilot plant treating hospital wastewater with relevant concentrations of these pharmaceuticals was evaluated for its performance to reduce the con...

journal_title：BioMed research international

authors： Langenhoff A,Inderfurth N,Veuskens T,Schraa G,Blokland M,Kujawa-Roeleveld K,Rijnaarts H

更新日期：2013-01-01 00:00:00

abstract：:Cerenkov luminescence imaging (CLI) can provide information of medical radionuclides used in nuclear imaging based on Cerenkov radiation, which makes it possible for optical means to image clinical radionuclide labeled probes. However, the exceptionally weak Cerenkov luminescence (CL) from Cerenkov radiation is suscep...

journal_title：BioMed research international

authors： Cao X,Li Y,Zhan Y,Chen X,Kang F,Wang J,Liang J

更新日期：2016-01-01 00:00:00

abstract：:Oxidative stress is a normal phenomenon in the body. Under normal conditions, the physiologically important intracellular levels of reactive oxygen species (ROS) are maintained at low levels by various enzyme systems participating in the in vivo redox homeostasis. Therefore, oxidative stress can also be viewed as an i...

journal_title：BioMed research international

authors： Rahal A,Kumar A,Singh V,Yadav B,Tiwari R,Chakraborty S,Dhama K

更新日期：2014-01-01 00:00:00

abstract：:Metabolic bone disorder is usually caused by abnormalities of minerals and hormones metabolism. Recently, it has been proved by several studies that the renin-angiotensin system (RAS) in local bone tissue is directly involved in bone metabolism. Activation of skeletal RAS plays an important role in bone metabolic diso...

journal_title：BioMed research international

authors： Gebru Y,Diao TY,Pan H,Mukwaya E,Zhang Y

更新日期：2013-01-01 00:00:00

abstract：:Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

journal_title：BioMed research international

authors： Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

更新日期：2014-01-01 00:00:00

abstract：:The hallucal sesamoid bones (HSBs), having an important role in reducing load per unit area on the first metatarsal head, can be injured commonly which also affected the first metatarsophalangeal joint and the surrounding structure. Meanwhile, differences among each HSB type may be a major factor affecting the occurre...

journal_title：BioMed research international

authors： Zhang L,Wang J,Liu J,Luo J

更新日期：2020-06-26 00:00:00

abstract：:The epilepsies are a heterogeneous group of neurological disorders and syndromes characterised by recurrent, involuntary, paroxysmal seizure activity, which is often associated with a clinicoelectrical correlate on the electroencephalogram. The diagnosis of epilepsy is usually made by a neurologist but can be difficul...

journal_title：BioMed research international

authors： Fergus P,Hignett D,Hussain A,Al-Jumeily D,Abdel-Aziz K

更新日期：2015-01-01 00:00:00

abstract：:The objective of the current research was to review and update evidence on the dietary effect of the consumption of tagatose in type 2 diabetes, as well as to elucidate the current approach that exists on its production and biotechnological utility in functional food for diabetics. Articles published before July 1, 20...

journal_title：BioMed research international

authors： Guerrero-Wyss M,Durán Agüero S,Angarita Dávila L

更新日期：2018-01-09 00:00:00

abstract：Background:Acute heart failure (AHF) is associated with disturbances of the peripheral perfusion leading to the dysfunction of many organs. Consequently, an episode of AHF constitutes a "multiple organ failure" which may also affect the skeletal muscles. However, the abnormalities within skeletal muscles during AHF hav...

journal_title：BioMed research international

authors： Węgrzynowska-Teodorczyk K,Siennicka A,Josiak K,Zymliński R,Kasztura M,Banasiak W,Ponikowski P,Woźniewski M

更新日期：2018-03-12 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：:Introduction. In the field of orthopaedic surgery, the use of osteogenic material in larger defects is essential. Autograft and allograft are both known methods, and autograft is believed to be the best choice. But autograft is associated with additional invasive procedures which can prove difficult in fragile patient...

journal_title：BioMed research international

authors： Dreyer CH,Rasmussen M,Pedersen RH,Overgaard S,Ding M

更新日期：2020-03-03 00:00:00

abstract：Objectives:Patients with stage 3 medication-related osteonecrosis of the jaw (MRONJ) suffer from severe complications. Chemotherapeutic agents and targeted drugs are considered to be associated with the development of MRONJ. However, little is known regarding the association of those agents with stage 3 MRONJ. The purp...

journal_title：BioMed research international

authors： Zhou Y,Yu Y,Shi Y,Li M,Yang C,Wang S

更新日期：2020-10-15 00:00:00

abstract：:The present study deals with the enzymatic synthesis of biodiesel by transesterification of Jatropha oil (Jatropha curcas L.) with ethanol in a solvent-free system. Seven commercial lipase preparations immobilized by covalent attachment on epoxy-polysiloxane-polyvinyl alcohol composite (epoxy-SiO2-PVA) were tested as ...

journal_title：BioMed research international

authors： Souza LT,Mendes AA,de Castro HF

更新日期：2016-01-01 00:00:00

abstract：:The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...

journal_title：BioMed research international

authors： Zhang H,Shen Y,Zhang Y,Li L,Wang X

更新日期：2018-01-29 00:00:00

abstract：Objective:Epidemiological studies have shown a correlation between periodontal disease (PD) and age-related macular degeneration (AMD). However, the results have been inconsistent, and no relevant meta-analysis has been performed on this topic. Hence, we performed a meta-analysis to evaluate whether the two diseases ar...

journal_title：BioMed research international

authors： Lv X,Li W,Fang Z,Xue X,Pan C

更新日期：2020-09-28 00:00:00

abstract：:Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evi...

journal_title：BioMed research international

authors： Vlahos NF,Theodoridis TD,Partsinevelos GA

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Spectroscopic analysis of urine samples from laboratory animals can be used to predict the efficacy and side effects of drugs. This employs methods combining (1)H NMR spectroscopy with quantification of biomarkers or with multivariate data analysis. The most critical steps in data evaluation are analytical...

journal_title：BioMed research international

authors： Schreier C,Kremer W,Huber F,Neumann S,Pagel P,Lienemann K,Pestel S

更新日期：2013-01-01 00:00:00

abstract：Purpose:To explore the effect of VEGF (vascular endothelial growth factor) on the vasculogenic mimicry (VM) formation of Choroidal Melanoma (CM) through PI3k signal pathway, to find novel targets for CM therapy. Methods:This research investigated the molecular mechanism of VEGF promoting VM formation of CM. First, we ...

journal_title：BioMed research international

authors： Xu X,Zong Y,Gao Y,Sun X,Zhao H,Luo W,Jia S

更新日期：2019-07-11 00:00:00

abstract：Background:In peritoneal dialysis (PD) patients, whether angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) could protect residual renal function is still controversial. To assess the effects of ACEIs and ARBs on the residual renal function and cardiovascular (CV) events in perito...

journal_title：BioMed research international

authors： Ding L,Yang J,Li L,Yang Y

更新日期：2020-09-23 00:00:00

abstract：:We evaluated the effects of mechanical stimulation on the osteogenic differentiation of human intraoral mesenchymal stem and progenitor cells (MSPCs) using the Flexcell FX5K Tension System that mediated cyclic tensile stretch on the cells. MSPCs were isolated from human mandibular retromolar bones and characterized us...

journal_title：BioMed research international

authors： Lohberger B,Kaltenegger H,Stuendl N,Payer M,Rinner B,Leithner A

更新日期：2014-01-01 00:00:00

abstract：:Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

journal_title：BioMed research international

authors： Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

更新日期：2016-01-01 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00

abstract：:We aim to investigate the effects of curcumin on preventing diabetes-induced vascular inflammation in association with its actions on Txnip, ICAM-1, and NOX2 enzyme expressions. Male Wistar rats were divided into four groups: control (CON), diabetic (DM; streptozotocin (STZ), i.v. 55 mg/kg BW), control-treated with cu...

journal_title：BioMed research international

authors： Wongeakin N,Bhattarakosol P,Patumraj S

更新日期：2014-01-01 00:00:00