Effect of Glucocorticoids on Ultrastructure of Myocardial Muscle in the Course of Experimentally Induced Acute Myocardial Ischemia.

Abstract:

:The search for effective methods of myocardial cytoprotection against ischemia is the most significant issue in modern cardiology and cardiac surgery. Glucocorticoids are deemed very strong modulators of inflammatory response and thus can potentially protect heart muscle from postreperfusion injury and myocardial ischemia during cardiac surgery. Ultrastructural examination of the left ventricle heart samples revealed that the intravenous application of dexamethasone and hydrocortisone proved to exert cytoprotective effect on cardiomyocytes during experimentally induced acute ischemia in rats.

journal_name

Biomed Res Int

authors

Kuropka P,Dobrzyński M,Gamian A,Gostomska-Pampuch K,Kuryszko J,Całkosiński I

doi

10.1155/2017/2108497

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

2108497

eissn

2314-6133

issn

2314-6141

journal_volume

2017

pub_type

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