The type III secretion system (T3SS) of Chlamydophila psittaci is involved in the host inflammatory response by activating the JNK/ERK signaling pathway.

abstract：:Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Agi...

journal_title：BioMed research international

authors： Pérez-Zepeda MU,Cesari M,Carrillo-Vega MF,Salinas-Escudero G,Tella-Vega P,García-Peña C

更新日期：2017-01-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently associated with obesity and insulin resistance. Even though lately some advances have been made to elucidate the mechanism and causes of the disease much remain...

journal_title：BioMed research international

authors： Duarte N,Coelho IC,Patarrão RS,Almeida JI,Penha-Gonçalves C,Macedo MP

更新日期：2015-01-01 00:00:00

abstract：:The regiospecific characteristics of n-3 polyunsaturated fatty acids (PUFAs) in triacylglycerol (TAG) significantly affect the physicochemical and physiological properties of marine fish oils. In this study, the TAG molecular species composition and positional distributions of fatty acids were investigated in three ma...

journal_title：BioMed research international

authors： Zhang H,Zhao H,Zhang Y,Shen Y,Su H,Jin J,Jin Q,Wang X

更新日期：2018-07-10 00:00:00

abstract：:The study aims to investigate the effects of the alcohol extract of Coreopsis tinctoria Nutt (AC) on diabetic nephropathy (DN) mice. A total of 30 db/db (DN) mice were divided into 3 groups, which were treated with AC (300 mg/kg/day), metformin (180 mg/kg/day), or saline by gavage for 10 weeks. Ten db/m mice treated w...

journal_title：BioMed research international

authors： Yu S,Zhao H,Yang W,Amat R,Peng J,Li Y,Deng K,Mao X,Jiao Y

更新日期：2019-03-28 00:00:00

abstract：:Introduction. Second-line antituberculosis drugs (SLDs) are used for treating multidrug-resistant tuberculosis (MDR-TB). Prolonged delays before confirming MDR-TB with drug susceptibility testing (DST) could result in transmission of drug-resistant strains and inappropriate use of SLDs, thereby increasing the risk of ...

journal_title：BioMed research international

authors： Chen Y,Yuan Z,Shen X,Wu J,Wu Z,Xu B

更新日期：2016-01-01 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：AIM:To evaluate the impact of SPARC on female sexual function. METHODS:151 women with a mean age of 60 ± 11.90 and SUI had a complete urodynamic investigation and underwent SPARC operation. 98 women completed the validated female sexual function index questionnaire (FSFI) at baseline and 94 women at follow-up. A minim...

journal_title：BioMed research international

authors： Al-Ali BM,Shamloul R,Hutterer GC,Puchwein E,Pummer K,Avian A,Primus G

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-HT2B receptor antagon...

journal_title：BioMed research international

authors： Janssen W,Schymura Y,Novoyatleva T,Kojonazarov B,Boehm M,Wietelmann A,Luitel H,Murmann K,Krompiec DR,Tretyn A,Pullamsetti SS,Weissmann N,Seeger W,Ghofrani HA,Schermuly RT

更新日期：2015-01-01 00:00:00

abstract：:[This retracts the article DOI: 10.1155/2019/5879089.]. ...

journal_title：BioMed research international

authors： BioMed Research International .

更新日期：2020-08-26 00:00:00

abstract：:This study tested the hypothesis that sensitivity of Escherichia coli to lactic acid at concentrations relevant for fermented sausages (pH 4.6, 150 mM lactic acid, aw = 0.92, temperature = 20 or 27°C) increases with increasing growth rate. For E. coli strain 683 cultured in TSB in chemostat or batch, subsequent inacti...

journal_title：BioMed research international

authors： Lindqvist R,Barmark G

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:In the process of care for disorders of sex development (DSD), clinical decisions should focus on the long-term quality of life (QOL). We sought to investigate the QOL of patients with DSD in China. DESIGN:Case-control study was carried out. PATIENTS:90 patients of DSD participated in the study. Finally, 87...

journal_title：BioMed research international

authors： Wang C,Tian Q

更新日期：2015-01-01 00:00:00

abstract：Background:Although sleeve gastrectomy results in good weight loss and metabolic improvements, it is an irreversible procedure. Therefore, we attempted to assess the possibility of creating a sleeved stomach without resection. Material and Methods. A total of 22 male Sprague-Dawley rats with type 2 diabetes were random...

journal_title：BioMed research international

authors： Zhang W,Widjaja J,Yao L,Shao Y,Zhu X,Li C

更新日期：2020-05-01 00:00:00

abstract：:Mouse lines selected for maximal (AIRmax) or minimal acute inflammatory reaction (AIRmin) were used to characterize the immune response and the influence of genetic background during pristane-induced arthritis (PIA). Susceptible AIRmax mice demonstrated exacerbated cellular profiles during PIA, with intense infiltrati...

journal_title：BioMed research international

authors： Correa MA,Borrego A,Jensen JR,Cabrera WHK,Barros M,Katz ISS,Canhamero T,Spadafora-Ferreira M,Fernandes JG,Starobinas N,Ribeiro OG,Ibañez OM,De Franco M

更新日期：2018-10-08 00:00:00

abstract：:Exposure to dioxins, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is reported to affect the autoimmune system and increase the risk of autoimmune disease. Generally, dioxin exerts its toxicity via aryl hydrocarbon receptor (AhR). Primary biliary cholangitis (PBC) is a chronic autoimmune disease, and its pathoge...

journal_title：BioMed research international

authors： She C,Wang J,Tang N,Liu Z,Xu L,Liu B

更新日期：2020-08-24 00:00:00

abstract：:Atypical chemokine receptors (ACKRs) are a subclass of G protein-coupled receptors characterized by promiscuity of ligand binding and an obvious inability to signal after ligand binding. Although some discoveries regarding this family in Homo sapiens and other species have been reported in some studies, the evolution ...

journal_title：BioMed research international

authors： Pan L,Lv J,Zhang Z,Zhang Y

更新日期：2018-09-24 00:00:00

abstract：:The aim was to evaluate three different biodegradable polylactic acid- (PLA-) based osteosynthesis materials (OM). These OM (BioSorb, LactoSorb, and Delta) were used in 64 patients of whom 55 (85.9%) had fractures of the zygoma, five (7.8%) in the LeFort II level, two of the frontal bone (3.1%), and two of the maxilla...

journal_title：BioMed research international

authors： Kolk A,Köhnke R,Saely CH,Ploder O

更新日期：2015-01-01 00:00:00

abstract：:This study is aimed at determining how oral squamous cell carcinoma (OSCC) regulates the angiogenesis of HUVECs through miR-210-3p expression and exploring the relationship among miR-210-3p, its target protein, and the possible mechanism of angiogenesis regulation. miR-210-3p expression was detected in OSCC tissues an...

journal_title：BioMed research international

authors： Wang H,Wang L,Zhou X,Luo X,Liu K,Jiang E,Chen Y,Shao Z,Shang Z

更新日期：2020-07-08 00:00:00

abstract：:Graphene is the first 2-dimensional material and possesses a plethora of original properties. Graphene and its derivatives have exhibited a great potential in a number of fields, both medical and nonmedical. The aim of this review is to set the theoretical basis for further research in developing graphene-based endova...

journal_title：BioMed research international

authors： Patelis N,Moris D,Matheiken S,Klonaris C

更新日期：2016-01-01 00:00:00

abstract：:Arthritogenic alphaviruses, including Ross River virus (RRV), Chikungunya virus (CHIKV), Sindbis virus (SINV), Mayaro virus (MAYV), O'nyong-nyong virus (ONNV), and Barmah Forest virus (BFV), cause incapacitating and long lasting articular disease/myalgia. Outbreaks of viral arthritis and the global distribution of the...

journal_title：BioMed research international

authors： Assunção-Miranda I,Cruz-Oliveira C,Da Poian AT

更新日期：2013-01-01 00:00:00

abstract：:It has been indicated that activation of peripheral imidazoline I2-receptor (I-2R) may reduce the blood pressure in spontaneously hypertensive rats (SHRs). Also, guanidinium derivatives show the ability to activate imidazoline receptors. Thus, it is of special interest to characterize the I-2R using guanidinium deriva...

journal_title：BioMed research international

authors： Chen MF,Tsai JT,Chen LJ,Wu TP,Yang JJ,Yin LT,Yang YL,Chiang TA,Lu HL,Wu MC

更新日期：2014-01-01 00:00:00

abstract：:Removal of MTA from dentin by applying 37% hydrochloric acid (HCl) to reduce microhardness and push-out bond strength. Forty dentin slices were filled with WMTA and divided into two groups (n = 20). Ten slices remained untreated while others were exposed to either HCl or phosphate buffer saline (PBS) and all samples w...

journal_title：BioMed research international

authors： Saghiri MA,Garcia-Godoy F,Gutmann JL,Sheibani N,Asatourian A,Lotfi M,Elyasi M

更新日期：2013-01-01 00:00:00

abstract：:Bone marrow-derived mesenchymal stem cells (BM-MSCs) represent a modern approach for management of chronic skin injuries. In this work, we describe BM-MSCs application versus their conditioned media (CM) when delivered topically admixed with fibrin glue to enhance the healing of chronic excisional wounds in rats. Fift...

journal_title：BioMed research international

authors： Mehanna RA,Nabil I,Attia N,Bary AA,Razek KA,Ahmed TA,Elsayed F

更新日期：2015-01-01 00:00:00

abstract：:Purpose. To report pilot data from a novel image analysis software "RetiView," to highlight clinically relevant information in RetCam images of infants with aggressive posterior retinopathy of prematurity (APROP). Methods. Twenty-three imaging sessions of consecutive infants of Asian Indian origin with clinically diag...

journal_title：BioMed research international

authors： Jayadev C,Vinekar A,Mohanachandra P,Desai S,Suveer A,Mangalesh S,Bauer N,Shetty B

更新日期：2015-01-01 00:00:00

abstract：:The polyherbal formulation containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol ex. Maton has been used for hypertension treatment empirically. Our previous study showed its blood pressure-lowering effect on a rat model of hypertension. However, toxicit...

journal_title：BioMed research international

authors： Sholikhah EN,Mustofa M,Nugrahaningsih DAA,Yuliani FS,Purwono S,Sugiyono S,Widyarini S,Ngatidjan N,Jumina J,Santosa D,Koketsu M

更新日期：2020-03-24 00:00:00

abstract：:Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...

journal_title：BioMed research international

authors： Yau SY,Gil-Mohapel J,Christie BR,So KF

更新日期：2014-01-01 00:00:00

abstract：:The role of α-fetoprotein (AFP) in the surveillance and diagnosis of hepatocellular carcinoma (HCC) has been questioned in recent years due to its low sensitivity and specificity. In addition to AFP, several new serum biomarkers, such as lens culinaris agglutinin-reactive fraction of AFP (AFP-L3) and des-gamma-carboxy...

journal_title：BioMed research international

authors： Wang X,Zhang Y,Yang N,He H,Tao X,Kou C,Jiang J

更新日期：2020-09-17 00:00:00

abstract：Purpose:Accumulated evidence suggests that reproductive factors are related to different breast cancer subtypes, but most studies on these relationships are mainly focused on middle-aged and older patients, and it remains unclear how reproductive factors impact different subtypes of breast cancer in young women. Metho...

journal_title：BioMed research international

authors： Wang JM,Wang J,Zhao HG,Liu TT,Wang FY

更新日期：2020-04-06 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/2643862.]. ...

journal_title：BioMed research international

authors： Cheng LG,He W,Zhang HX,Song Q,Ning B,Li HZ,He Y,Lin S

更新日期：2017-01-01 00:00:00

abstract：:GABAergic inhibition and particularly perisomatic inhibition play a crucial role in controlling the firing properties of large principal cell populations. Furthermore, GABAergic network is a key element in the therapy attempting to reduce epileptic activity. Here, we present a review showing the synaptic changes of pe...

journal_title：BioMed research international

authors： Wittner L,Maglóczky Z

更新日期：2017-01-01 00:00:00

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00