Metabolomics application in maternal-fetal medicine.

Abstract:

:Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, cord blood, placenta, urine, and vaginal secretions. All published papers highlight the strong correlation between biomarkers found in these tissues and fetal malformations, preterm delivery, premature rupture of membranes, gestational diabetes mellitus, preeclampsia, neonatal asphyxia, and hypoxic-ischemic encephalopathy. The aim of this review is to summarize and comment on original data available in relevant published works in order to emphasize the clinical potential of metabolomics in obstetrics in the immediate future.

journal_name

Biomed Res Int

authors

Fanos V,Atzori L,Makarenko K,Melis GB,Ferrazzi E

doi

10.1155/2013/720514

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

720514

eissn

2314-6133

issn

2314-6141

journal_volume

2013

pub_type

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