Abstract:
:Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant women, fetuses and newborns are amniotic fluid, blood, plasma, cord blood, placenta, urine, and vaginal secretions. All published papers highlight the strong correlation between biomarkers found in these tissues and fetal malformations, preterm delivery, premature rupture of membranes, gestational diabetes mellitus, preeclampsia, neonatal asphyxia, and hypoxic-ischemic encephalopathy. The aim of this review is to summarize and comment on original data available in relevant published works in order to emphasize the clinical potential of metabolomics in obstetrics in the immediate future.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Fanos V,Atzori L,Makarenko K,Melis GB,Ferrazzi Edoi
10.1155/2013/720514subject
Has Abstractpub_date
2013-01-01 00:00:00pages
720514eissn
2314-6133issn
2314-6141journal_volume
2013pub_type
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