Automatic detection and quantification of acute cerebral infarct by fuzzy clustering and histographic characterization on diffusion weighted MR imaging and apparent diffusion coefficient map.

Abstract:

:Determination of the volumes of acute cerebral infarct in the magnetic resonance imaging harbors prognostic values. However, semiautomatic method of segmentation is time-consuming and with high interrater variability. Using diffusion weighted imaging and apparent diffusion coefficient map from patients with acute infarction in 10 days, we aimed to develop a fully automatic algorithm to measure infarct volume. It includes an unsupervised classification with fuzzy C-means clustering determination of the histographic distribution, defining self-adjusted intensity thresholds. The proposed method attained high agreement with the semiautomatic method, with similarity index 89.9 ± 6.5%, in detecting cerebral infarct lesions from 22 acute stroke patients. We demonstrated the accuracy of the proposed computer-assisted prompt segmentation method, which appeared promising to replace the laborious, time-consuming, and operator-dependent semiautomatic segmentation.

journal_name

Biomed Res Int

authors

Tsai JZ,Peng SJ,Chen YW,Wang KW,Wu HK,Lin YY,Lee YY,Chen CJ,Lin HJ,Smith EE,Yeh PS,Hsin YL

doi

10.1155/2014/963032

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

963032

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章
  • Carbapenem-Resistant Klebsiella pneumoniae Infections among ICU Admission Patients in Central China: Prevalence and Prediction Model.

    abstract:Objective:To investigate the prevalence of infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) among ICU admission patients in central China and develop a reliable prediction model. Methods:Five hundred and seven consecutive ICU admission patients with Klebsiella pneumoniae (KP) infection were enrolled...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/9767313

    authors: Li Y,Shen H,Zhu C,Yu Y

    更新日期:2019-03-27 00:00:00

  • Influence of Acquisition Time on MR Image Quality Estimated with Nonparametric Measures Based on Texture Features.

    abstract::Correlation of parametrized image texture features (ITF) analyses conducted in different regions of interest (ROIs) overcomes limitations and reliably reflects image quality. The aim of this study is to propose a nonparametrical method and classify the quality of a magnetic resonance (MR) image that has undergone cont...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3706581

    authors: Obuchowicz R,Piórkowski A,Urbanik A,Strzelecki M

    更新日期:2019-11-20 00:00:00

  • In Vivo Imaging of Neutrophil Extracellular Traps (NETs): Visualization Methods and Outcomes.

    abstract::Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2020/4192745

    authors: Alasmari SZ

    更新日期:2020-02-01 00:00:00

  • Health Effects of 12 Weeks of Team-Sport Training and Fitness Training in a Community Health Centre for Sedentary Men with Lifestyle Diseases.

    abstract::This study compares the effects of team-sport training, for sedentary men with lifestyle diseases, with fitness training in a pragmatic set-up in a community health centre (CHC). Thirty-two men in the fitness group (FiG) and 36 men in the team-sport group (TsG) completed the training and trained for 60-90 min, two tim...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2018/1571807

    authors: Møller TK,Nielsen TT,Andersen R,Lundager I,Hansen HF,Ottesen L,Krustrup P,Randers MB

    更新日期:2018-05-15 00:00:00

  • Clinical and Prognostic Significance of Positive Hepatojugular Reflux on Discharge in Acute Heart Failure: Insights from the ESCAPE Trial.

    abstract::Background. There has been a decline in emphasis of the value of physical examination in heart failure (HF) with increased reliance on cardiac imaging. We aim to study the clinical and prognostic significance of positive hepatojugular reflux (HJR) on discharge in patients hospitalized with HF. Methods. Using the ESCAP...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5734749

    authors: Omar HR,Guglin M

    更新日期:2017-01-01 00:00:00

  • Virulence factors associated with pediatric shigellosis in Brazilian Amazon.

    abstract::Shigellosis is a global human health problem and the incidence is highest among children. In the present work, main Shigella virulence genes was examined by PCR and compared to symptoms of pediatric shigellosis. Thirty Shigella isolates were identified from an etiologic study at which 1,339 children ranging 0-10 years...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/539697

    authors: da Cruz CB,de Souza MC,Serra PT,Santos I,Balieiro A,Pieri FA,Nogueira PA,Orlandi PP

    更新日期:2014-01-01 00:00:00

  • Effect of Computer Navigation on Accuracy and Reliability of Limb Alignment Correction following Open-Wedge High Tibial Osteotomy: A Meta-Analysis.

    abstract:Background:It is unclear whether computer navigation can improve the accuracy and reliability of targeted lower limb alignment correction following open-wedge high tibial osteotomy (HTO). This meta-analysis was designed to compare the accuracy and reliability of limb alignment correction between computer navigated and ...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2017/3803457

    authors: Han SB,Kim HJ,Lee DH

    更新日期:2017-01-01 00:00:00

  • Predicting flavin and nicotinamide adenine dinucleotide-binding sites in proteins using the fragment transformation method.

    abstract::We developed a computational method to identify NAD- and FAD-binding sites in proteins. First, we extracted from the Protein Data Bank structures of proteins that bind to at least one of these ligands. NAD-/FAD-binding residue templates were then constructed by identifying binding residues through the ligand-binding d...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/402536

    authors: Lu CH,Yu CS,Lin YF,Chen JY

    更新日期:2015-01-01 00:00:00

  • Risk Factors for Hepatocellular Carcinoma Recurrence and Survival after Liver Transplantation in Patients with HCV-Related Cirrhosis.

    abstract:Purpose:We aimed to identify prognostic factors for survival and recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) for patients with HCC and hepatitis C virus-related cirrhosis (HCV-cirrhosis). Methods:This retrospective cohort study followed all adult patients with HCV-cirrhosis who underw...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/1487593

    authors: Vidal RIO,Vidal EIO,Pereira BB,Assane CC,Ribeiro A,do Nascimento EM,Romeiro FG,Ribeiro Filho J

    更新日期:2020-10-17 00:00:00

  • Two-dimensional PCA highlights the differentiated antitumor and antimicrobial activity of methanolic and aqueous extracts of Laurus nobilis L. from different origins.

    abstract::Natural matrices are important sources of new antitumor and antimicrobial compounds. Species such as Laurus nobilis L. (laurel) might be used for this purpose, considering its medicinal properties. Herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/520464

    authors: Dias MI,Barreira JC,Calhelha RC,Queiroz MJ,Oliveira MB,Soković M,Ferreira IC

    更新日期:2014-01-01 00:00:00

  • Black stain and dental caries: a review of the literature.

    abstract::Black stain is characterized as a dark line or an incomplete coalescence of dark dots localized on the cervical third of the tooth. Over the last century, the etiology of black stain has been the subject of much debate. Most of the studies concerning this issue were conducted in pediatric population. According to the ...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/469392

    authors: Żyła T,Kawala B,Antoszewska-Smith J,Kawala M

    更新日期:2015-01-01 00:00:00

  • Angiopoietin-1 Promotes the Integrity of Neovascularization in the Subcutaneous Matrigel of Type 1 Diabetic Rats.

    abstract:Objective:This study aimed to investigate the effects of Ang-1 on neovascularization of diabetic organs by subcutaneous Matrigel angiogenesis model, established in type 1 diabetic rats. Methods:Ang-1 adenoviral vector was constructed. The rat model was established by STZ and divided into four group. The Matrigel was i...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/2016972

    authors: Li S,Zou H,Gong M,Chen Y,Yan X,Yu L,Yang Y

    更新日期:2019-01-09 00:00:00

  • Helminth parasites alter protection against Plasmodium infection.

    abstract::More than one-third of the world's population is infected with one or more helminthic parasites. Helminth infections are prevalent throughout tropical and subtropical regions where malaria pathogens are transmitted. Malaria is the most widespread and deadliest parasitic disease. The severity of the disease is strongly...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2014/913696

    authors: Salazar-Castañon VH,Legorreta-Herrera M,Rodriguez-Sosa M

    更新日期:2014-01-01 00:00:00

  • Knockdown of PHF5A Inhibits Migration and Invasion of HCC Cells via Downregulating NF-κB Signaling.

    abstract:Background:Inflammation is the major risk factor for the progression of hepatocellular carcinoma (HCC), and the nuclear factor-κB (NF-κB) signaling plays the central role in the inflammation process. However, the activated mechanism of NF-κB signaling in HCC is unclear. Methods:The expression of PHF5A is examined by q...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/1621854

    authors: Yang Q,Zhang J,Xu S,Jia C,Meng W,Tang H,Zhang X,Zhang Y,Fu B

    更新日期:2019-01-15 00:00:00

  • Galangin Suppresses Renal Inflammation via the Inhibition of NF-κB, PI3K/AKT and NLRP3 in Uric Acid Treated NRK-52E Tubular Epithelial Cells.

    abstract::Renal inflammation can result in renal injury. Uric acid (UA) is the final product of purine metabolism in humans and because of the lack of urate oxidase, UA may accumulate in tissues, including kidney, causing inflammation. Galangin was isolated from a traditional Chinese medicine plant and possesses several benefic...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/3018357

    authors: Lu H,Yao H,Zou R,Chen X,Xu H

    更新日期:2019-05-26 00:00:00

  • Chronic traumatic encephalopathy and suicide: a systematic review.

    abstract::Traumatic brain injury (TBI) is a global health concern, and the recent literature reports that a single mild TBI can result in chronic traumatic encephalopathy (CTE). It has been suggested that CTE may lead to death by suicide, raising important prevention, treatment, and policy implications. Thus, we conducted a sys...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1155/2013/424280

    authors: Wortzel HS,Shura RD,Brenner LA

    更新日期:2013-01-01 00:00:00

  • Evaluation of the Therapeutic Effect of a Flavonoid Prescription against Rabbit Hemorrhagic Disease In Vivo.

    abstract::Rabbit hemorrhagic disease (RHD) is an acute, high fatal contagious disease induced by rabbit hemorrhagic disease virus (RHDV) with acute severe hepatic injury and causes huge economic loss worldwide. In order to develop an effective and reliable drug to treat this disease in clinic, a prescription formulated with bai...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/5201790

    authors: Du H,Zhang S,He M,Ming K,Wang J,Yuan W,Qiao M,Wu Y,Wang D,Hu Y,Liu J

    更新日期:2019-04-04 00:00:00

  • Effect of Different Body Postures on the Severity of Stuttering in Young Adults with Developmental Stuttering.

    abstract:Objective:The current study aimed to investigate the effects of body position on the level and severity of stuttering in young adults with developmental stuttering. Methods:A total of 24 subjects (male: 17; female: 7; mean age: 24.9 ± 6.2 years) with developmental stuttering participated. The participants were asked t...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/1817906

    authors: Almudhi A,Zafar H,Anwer S,Alghadir A

    更新日期:2019-08-05 00:00:00

  • Efficacy and safety of hepatectomy performed with intermittent portal triad clamping with low central venous pressure.

    abstract:BACKGROUND:This retrospective study was designed to investigate the efficacy and safety of intermittent portal triad clamping (PTC) with low central venous pressure (CVP) in liver resections. METHODS:Between January 2007 and August 2013, 115 patients underwent liver resection with intermittent PTC. The patients' data ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/297971

    authors: Topaloglu S,Yesilcicek Calik K,Calik A,Aydın C,Kocyigit S,Yaman H,Kutanis D,Karabulut E,Dohman D,Orem A,Arslan MK

    更新日期:2013-01-01 00:00:00

  • Effects of Short-Term Low-Dose Glucocorticoids for Patients with Mild COVID-19.

    abstract:Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/2854186

    authors: Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

    更新日期:2020-09-23 00:00:00

  • Potential Role of the Last Half Repeat in TAL Effectors Revealed by a Molecular Simulation Study.

    abstract::TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/8036450

    authors: Wan H,Chang S,Hu JP,Tian XH,Wang MH

    更新日期:2016-01-01 00:00:00

  • Identification of Biomarkers to Construct a Competing Endogenous RNA Network and Establishment of a Genomic-Clinicopathologic Nomogram to Predict Survival for Children with Rhabdoid Tumors of the Kidney.

    abstract::Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/5843874

    authors: Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

    更新日期:2020-08-26 00:00:00

  • Translation and Cross-Cultural Adaptation of SATIS-Stroke for Use in Brazil: A Satisfaction Measure of Activities and Participation in Stroke Survivors.

    abstract:Introduction:SATIS-Stroke was developed to measure satisfaction regarding activities and participation among stroke survivors based on the concepts contained in the International Classification of Functioning, Disability, and Health. However, this measure is only available in English and French. Objective:Perform the ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/8054640

    authors: Pereira GS,Silva SM,Júlio CE,Thonnard JL,Bouffioulx E,Corrêa JCF,Corrêa FI

    更新日期:2019-02-18 00:00:00

  • Effects of various antiepileptics used to alleviate neuropathic pain on compound action potential in frog sciatic nerves: comparison with those of local anesthetics.

    abstract::Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conduction inhibitions by l...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/540238

    authors: Uemura Y,Fujita T,Ohtsubo S,Hirakawa N,Sakaguchi Y,Kumamoto E

    更新日期:2014-01-01 00:00:00

  • Effect of Bitter Compounds on the Expression of Bitter Taste Receptor T2R7 Downstream Signaling Effectors in cT2R7/pDisplay-Gα16/gust44/pcDNA3.1 (+) Cells.

    abstract::Bitterness is an important taste sensation for chickens, which provides useful sensory information for acquisition and selection of diet, and warns them against ingestion of potentially harmful and noxious substances in nature. Bitter taste receptors (T2Rs) mediate the recognition of bitter compounds belonging to a fa...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2019/6301915

    authors: Su Y,Jie H,Zhu Q,Zhao X,Wang Y,Yin H,Kumar Mishra S,Li D

    更新日期:2019-10-31 00:00:00

  • Antitumor and antiangiogenic activities of curcumin in cervical cancer xenografts in nude mice.

    abstract::To evaluate the effects of curcumin (CUR) on tumor progression and angiogenesis in cervical cancer- (CaSki-) implanted nude mice and on the angiogenic biomarkers: vascular endothelial growth factor (VEGF), cyclooxygenase-2 (COX-2), and epidermal growth factor receptor (EGFR). CaSki cells were subcutaneously injected i...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/817972

    authors: Yoysungnoen-Chintana P,Bhattarakosol P,Patumraj S

    更新日期:2014-01-01 00:00:00

  • Optimization of dairy sludge for growth of Rhizobium cells.

    abstract::In this study dairy sludge was evaluated as an alternative cultivation medium for Rhizobium. Growth of bacterial strains at different concentrations of Dairy sludge was monitored. Maximum growth of all strains was observed at 60% Dairy sludge concentration. At 60% optical density (OD) values are 0.804 for Rhizobium tr...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/845264

    authors: Singh AK,Singh G,Gautam D,Bedi MK

    更新日期:2013-01-01 00:00:00

  • Tracking Transplanted Stem Cells Using Magnetic Resonance Imaging and the Nanoparticle Labeling Method in Urology.

    abstract::A reliable in vivo imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. Most stem cell transplantation studies have used immunohistological staining, which does not provide information about the migration of transplanted cells in vivo in the...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/231805

    authors: Kim JH,Lee HJ,Song YS

    更新日期:2015-01-01 00:00:00

  • An alternative approach to protein folding.

    abstract::A diffusion theory-based, all-physical ab initio protein folding simulation is described and applied. The model is based upon the drift and diffusion of protein substructures relative to one another in the multiple energy fields present. Without templates or statistical inputs, the simulations were run at physiologic ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/583045

    authors: Kang Y,Fortmann CM

    更新日期:2013-01-01 00:00:00

  • Gremlin activates the Smad pathway linked to epithelial mesenchymal transdifferentiation in cultured tubular epithelial cells.

    abstract::Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/802841

    authors: Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

    更新日期:2014-01-01 00:00:00