A comparative analysis of biomarker selection techniques.

abstract：Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults...

journal_title：BioMed research international

authors： Li J,Zhu W,Gao X,Li X

更新日期：2020-03-03 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of liver disease worldwide and afflicts adults and children as currently associated with obesity and insulin resistance. Even though lately some advances have been made to elucidate the mechanism and causes of the disease much remain...

journal_title：BioMed research international

authors： Duarte N,Coelho IC,Patarrão RS,Almeida JI,Penha-Gonçalves C,Macedo MP

更新日期：2015-01-01 00:00:00

abstract：:The primary goal of this work was to study advantages of numerical methods used for the creation of continuous time Markov chain models (CTMC) of voltage gating of gap junction (GJ) channels composed of connexin protein. This task was accomplished by describing gating of GJs using the formalism of the stochastic autom...

journal_title：BioMed research international

authors： Snipas M,Pranevicius H,Pranevicius M,Pranevicius O,Paulauskas N,Bukauskas FF

更新日期：2015-01-01 00:00:00

abstract：Introduction:Even today, despite medical progress and intensive health education, odontogenic infections leading to surgical intervention and hospitalization are common in children and young people. The aim of this study was to give a detailed overview of clinical and economic data on children and young people treated ...

journal_title：BioMed research international

authors： Doll C,Carl F,Neumann K,Voss JO,Hartwig S,Waluga R,Heiland M,Raguse JD

更新日期：2018-08-26 00:00:00

abstract：BACKGROUND AND AIM:Chemokine/receptor axis is a predominant actor of clinical disorders. They are key factors of pathogenesis of almost all clinical situations including asthma. Correspondingly, CXCL12 is involved in the immune responses. Therefore, this study was designed to explore the association between gene polymo...

journal_title：BioMed research international

authors： Rafatpanah H,Amin M,Ghasemshirazi M,Kazemiarababadi M,Khorramdelazad H,Abousaidi H,Shabani Z,Sayadi A,Hassanshahi G,Samadi J

更新日期：2013-01-01 00:00:00

abstract：:Iron deficiency anemia has been a widespread disease. As an effective and stable iron supplement, the physiochemical properties of the polysaccharide iron complex have been widely studied. In this study, we characterized a novel polysaccharide-iron(III) complex extracted in an edible fungal species Auricularia auricul...

journal_title：BioMed research international

authors： Liu T,Liu T,Liu H,Fan H,Chen B,Wang D,Zhang Y,Sun F

更新日期：2019-06-11 00:00:00

abstract：PURPOSE:To evaluate tumor structure in children with diffuse intrinsic pontine glioma (DIPG) using histogram analyses of mean diffusivity (MD), determine potential treatment and corticosteroid-related effects on MD, and monitor changes in MD distributions over time. MATERIALS AND METHODS:DTI was performed on a 1.5T GE...

journal_title：BioMed research international

authors： Steffen-Smith EA,Sarlls JE,Pierpaoli C,Shih JH,Bent RS,Walker L,Warren KE

更新日期：2014-01-01 00:00:00

abstract：:Aims. We describe a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method to quantify and compare simultaneously global methylation and hydroxymethylation in human DNA of different tissues. Materials and Methods. Blood and saliva DNA from fourteen volunteers was processed for epigenetic endpoints using LC-M...

journal_title：BioMed research international

authors： Godderis L,Schouteden C,Tabish A,Poels K,Hoet P,Baccarelli AA,Van Landuyt K

更新日期：2015-01-01 00:00:00

abstract：:Although disorders of the stomatognathic system are common, the mechanisms involved are unknown. Our objective was to study the changes in the masseter muscles after unilateral exodontia. Molar extraction was performed on Wistar rats (left side), and the animals were sacrificed after either 14 or 26 days. The masseter...

journal_title：BioMed research international

authors： Guerra Cde S,Carla Lara Pereira Y,Issa JP,Luiz KG,Guimarães EA,Gerlach RF,Iyomasa MM

更新日期：2014-01-01 00:00:00

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00

abstract：:As the heart transitions from one exercise intensity to another, changes in cardiac output occur, which are modulated by alterations in force development and calcium handling. Although the steady-state force-calcium relationship at various heart rates is well investigated, regulation of these processes during transiti...

journal_title：BioMed research international

authors： Haizlip KM,Milani-Nejad N,Brunello L,Varian KD,Slabaugh JL,Walton SD,Gyorke S,Davis JP,Biesiadecki BJ,Janssen PM

更新日期：2015-01-01 00:00:00

abstract：:J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer propertie...

journal_title：BioMed research international

authors： Feng P,Lin H,Chen W,Zuo Y

更新日期：2014-01-01 00:00:00

abstract：:Background. In most reports on ECMO treatment, advanced age is classified as a contraindication to VA ECMO. We attempted to investigate whether advanced age would be a main risk factor deciding VA ECMO application and performing VA ECMO support. We determined whether advanced age should be regarded as an absolute or r...

journal_title：BioMed research international

authors： Lee W,Kim Y,Choi H,Kim H,Lee S,Lee H,Chee H,Kim J,Hwang J,Lee S,Kim Y,Cho S,Ryu S,Park S

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl2 on autophagy and muscle atrophy are still unclear. METHODS:C2C12 myotubes were exposed to increasing concentrat...

journal_title：BioMed research international

authors： Chen R,Jiang T,She Y,Xu J,Li C,Zhou S,Shen H,Shi H,Liu S

更新日期：2017-01-01 00:00:00

abstract：Objective:Primary headache and obesity are highly prevalent disorders in the general population. Although many studies have reported an association between the two, there is still no overall comprehension about this relationship. To gain a more accurate understanding in this regard, we analyzed data from a 2011 cross-s...

journal_title：BioMed research international

authors： Huang Q,Yu H,Zhang N,Guo B,Feng C,Wang S,Liang X

更新日期：2019-04-15 00:00:00

abstract：:High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...

journal_title：BioMed research international

authors： Mardente S,Mari E,Massimi I,Fico F,Faggioni A,Pulcinelli F,Antonaci A,Zicari A

更新日期：2015-01-01 00:00:00

abstract：:In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of in vivo and in vitro studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly...

journal_title：BioMed research international

authors： Sun B,Kong DR,Li SW,Yu DF,Wang GJ,Yu FF,Wu Q,Xu JM

更新日期：2016-01-01 00:00:00

abstract：:After decades of intensive searching for antimicrobial compounds derived from actinobacteria, the frequency of isolation of new molecules has decreased. To cope with this concern, studies have focused on the exploitation of actinobacteria from unexplored environments and actinobacteria symbionts of plants and animals....

journal_title：BioMed research international

authors： Mendes TD,Borges WS,Rodrigues A,Solomon SE,Vieira PC,Duarte MC,Pagnocca FC

更新日期：2013-01-01 00:00:00

abstract：:Estimation of the spread and advancement of Plasmodium falciparum artemisinin-resistant parasites can be done by probing polymorphisms in the kelch (Pfk13) domain (a validated molecular marker). This study aimed to provide baseline information for future artemisinin surveillance by analyzing the k13-propeller domain i...

journal_title：BioMed research international

authors： Rana R,Ranjit M,Bal M,Khuntia HK,Pati S,Krishna S,Das A

更新日期：2020-03-15 00:00:00

abstract：:Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza Bunge, has shown an antiproliferative activity on various human cancer cell lines including nasopharyngeal carcinoma cells. However, the effects of Tan IIA on human oral cancer cells are still unknown. This study aimed to invest...

journal_title：BioMed research international

authors： Tseng PY,Lu WC,Hsieh MJ,Chien SY,Chen MK

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:This study aims to explore the usage of intraocular pressure measurements as the early indicator of the increase in intra-abdominal pressure. METHODS:In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients. The control group (Gro...

journal_title：BioMed research international

authors： Ece I,Vatansev C,Kucukkartallar T,Tekin A,Kartal A,Okka M

更新日期：2015-01-01 00:00:00

abstract：:Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease, which manifests as a succession of outbreaks. OLP was associated with salivary oxidative stress. Randomized, double blind, parallel-group study was performed. The sample consisted of 55 clinically and histopathologically diagnosed OLP patients. ...

journal_title：BioMed research international

authors： Tvarijonaviciute A,Aznar-Cayuela C,Rubio CP,Tecles F,Ceron JJ,López-Jornet P

更新日期：2018-05-27 00:00:00

abstract：:Protein phosphorylation is catalyzed by kinases which regulate many aspects that control death, movement, and cell growth. Identification of the phosphorylation site-specific kinase-substrate relationships (ssKSRs) is important for understanding cellular dynamics and provides a fundamental basis for further disease-re...

journal_title：BioMed research international

authors： Wang M,Wang T,Wang B,Liu Y,Li A

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Osteomyelitis is a severe orthopaedic complication which is difficult to diagnose and treat. Previous experimental studies mainly focussed on evaluating osteomyelitis in the presence of an implant or used a sclerosing agent to promote infection onset. In contrast, we focused on the longitudinal assessment ...

journal_title：BioMed research international

authors： Odekerken JC,Walenkamp GH,Brans BT,Welting TJ,Arts JJ

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is one of the major metabolic disorders that is currently threatening the world. DM is seen associated with obesity and diabetic retinopathy (DR). In the present paper we tried to evaluate the relationship between the three aliments at the gene level and further performed the molecular docking t...

journal_title：BioMed research international

authors： Rampogu S,Rampogu Lemuel M

更新日期：2016-01-01 00:00:00

abstract：:Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane h...

journal_title：BioMed research international

authors： Gabarre S,Herrera A,Mateo J,Ibarz E,Lobo-Escolar A,Gracia L

更新日期：2014-01-01 00:00:00

abstract：:5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...

journal_title：BioMed research international

authors： Zhu Y,Xu L,Fan Y,Li C,Zhang Y,Zheng H,Hou K,Qu X,Liu Y

更新日期：2013-01-01 00:00:00

abstract：:The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular...

journal_title：BioMed research international

authors： Yang M,Sheng L,Zhang TR,Li Q

更新日期：2013-01-01 00:00:00

abstract：:A potent fibrinolytic enzyme-producing Bacillus cereus IND1 was isolated from the Indian food, rice. Solid-state fermentation was carried out using agroresidues for the production of fibrinolytic enzyme. Among the substrates, wheat bran supported more enzyme production and has been used for the optimized enzyme produc...

journal_title：BioMed research international

authors： Vijayaraghavan P,Vincent SG

更新日期：2014-01-01 00:00:00

abstract：:Severe stages of acute, colonic diverticulitis can progress into intestinal perforations with peritonitis. In such cases, urgent treatment is needed, and Hartmann's procedure is the standard treatment for cases with fecal peritonitis. Peritoneal lavage may be an alternative to resection for acute diverticulitis with p...

journal_title：BioMed research international

authors： Hupfeld L,Burcharth J,Pommergaard HC,Rosenberg J

更新日期：2014-01-01 00:00:00