Abstract:
:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searched PubMed and EMBASE for trials published from 1980 to 2016. We included 11 cohort studies that reported relative risks with 95% confidence intervals for the association of AMD and mortality, involving 57,069 participants. In a random-effects model, the adjusted RR (95% confidence interval) associated with AMD was 1.09 (1.02-1.17) for all-cause mortality. Findings from this research provide support that persons with AMD had a higher subsequent risk of mortality than persons without AMD.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Wang P,Wang J,Ma J,Jin G,Guan Xdoi
10.1155/2017/3489603subject
Has Abstractpub_date
2017-01-01 00:00:00pages
3489603eissn
2314-6133issn
2314-6141journal_volume
2017pub_type
杂志文章,meta分析abstract:Objective:To investigate the clinicopathological characteristics and risk factors in patients with lung cancer and COPD. Materials and Methods:We retrospectively reviewed the clinical data of 282 patients with lung cancer, including 174 and 108 patients with and without COPD, respectively. Information on age, sex, smo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8398156
更新日期:2018-02-14 00:00:00
abstract::In clinical endodontics, preoperative estimation of root canal curvature is crucial regarding the prevention of iatrogenic errors. Reproduction of the two-dimensional radiographic images causes certain proximal view curvatures not seen. Therefore, the present study is aimed at investigating the degree of root canal cu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2021/6699635
更新日期:2021-01-13 00:00:00
abstract::Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/2931402
更新日期:2018-12-26 00:00:00
abstract::Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/147196
更新日期:2015-01-01 00:00:00
abstract::Chosen aspects of examinations of inorganic gunshot particles by means of scanning electron microscopy and energy dispersive X-ray spectrometry technique are presented. The research methodology of particles was worked out, which included a precise and repeatable procedure of the automatic detection and identification ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/428038
更新日期:2014-01-01 00:00:00
abstract::Trichoderma spp. are important biocontrol filamentous fungi and have tremendous potential in soil bioremediation. In our previous studies, a C2H2 type transcription factor coding gene (thmea1) was cloned from a biocontrol agent T. harzianum Th-33; the encoded sequence of thmea1 contained 3 conserved C2H2 domains with ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8149682
更新日期:2018-07-18 00:00:00
abstract:OBJECTIVE:To explore the safety and efficacy of transpseudarthrosis osteotomy with interbody fusion in the treatment of Ankylosing Spondylitis (AS) patients with kyphotic spinal pseudarthrosis by a single posterior approach. METHODS:Twelve consecutive patients with spinal pseudarthrosis underwent transpseudarthrosis o...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/4079849
更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to find out the ideal cut-off level of phosphate for safe healing when deformity correction and concomitant lengthening are indicated in the two different skeletal maturity groups of patients with rickets. Thirty-nine hypophosphatemic rickets patients were selected for the study and were divi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/569530
更新日期:2014-01-01 00:00:00
abstract::The purpose of this study is to evaluate the therapeutic effects of human umbilical cord-derived mesenchymal stem cells (hUC-MSC) activated by curcumin (CUR) on PC12 cells induced by 1-methyl-4-phenylpyridinium ion (MPP+), a cell model of Parkinson's disease (PD). The supernatant of hUC-MSC and hUC-MSC activated by 5 ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/9140541
更新日期:2016-01-01 00:00:00
abstract::Taking into account that there are controversial antioxidative effects of inhalational anesthetics isoflurane and sevoflurane and absence of comparison of genotoxicity of both anesthetics in animal model, the aim of this study was to compare DNA damage and antioxidant status in Wistar rats exposed to a single time to ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/264971
更新日期:2015-01-01 00:00:00
abstract::High-grade gliomas are the main cause of death in children with brain tumours. Despite recent advances in cancer therapy, their prognosis remains poor and the treatment is still challenging. To date, surgery followed by radiotherapy and temozolomide is the standard therapy. However, increasing knowledge of glioma biol...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/215135
更新日期:2015-01-01 00:00:00
abstract::The insulin pathway is an anabolic pathway that controls, amongst other things, glucose homeostasis. It is an evolutionarily conserved pathway. Disruptions in insulin pathway functions can lead to diabetic states. Diabetes, a very common occurrence in modern life, afflicts a significant portion of the population of de...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1451623
更新日期:2019-01-22 00:00:00
abstract::Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/7323508
更新日期:2017-01-01 00:00:00
abstract:Objective:This study aims to investigate the effect of systemically administrated zoledronate on bone-implant fixation in animal models. Methods:We searched MEDLINE, Embase, and EBSCO for studies that explore the role of systemic or local zoledronate delivery in implant osseointegration in animal models. The Review Ma...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析,评审
doi:10.1155/2019/9541485
更新日期:2019-09-22 00:00:00
abstract::This investigation was aimed at assessing a possible interaction of a traditional Thai herbal recipe, "Ya-Sa-Marn-Phlae (YSMP)," used for wound treatments with topical antiseptics, povidone-iodine (PI) solution and hydrogen peroxide (H2O2), and effects of THR-SK010 alone and the combinations on Staphylococcus aureus. ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/867603
更新日期:2014-01-01 00:00:00
abstract::Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and exist as an important cause of pulmonary infections in humans. Pulmonary involvement is the most common disease manifestation of NTM and the incidence of NTM is growing in North America. Susceptibility to NTM infection is incompletely understood; ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/919474
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To assess whether high-molecular-weight proteins excretion predicts outcome and therapy-responsiveness in patients with FSGS and nephrotic syndrome. RESEARCH DESIGN AND METHODS:Thirty-eight patients measured at biopsy fractional excretion of IgG (FEIgG) and urinary α2-macroglobulin/creatinine ratio ( α m/C)....
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/941831
更新日期:2013-01-01 00:00:00
abstract:Background:The pathogenesis of abdominal aortic aneurysm (AAA) is characterized by atherosclerosis with chronic inflammation in the aortic wall. Montelukast is a selective cys-LT 1 receptor antagonist that can suppress atherosclerotic diseases. We evaluated the in vitro properties of montelukast and its in vivo activit...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9104680
更新日期:2019-05-27 00:00:00
abstract:Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/5076516
更新日期:2020-11-03 00:00:00
abstract::We aimed to assess the prevalence of hospitalization for endometriosis in the general population in France and in each French region and to describe temporal trends, rehospitalization rates, and prevalence of the different types of endometriosis. The analyses were carried out on French hospital discharge data and cove...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3260952
更新日期:2016-01-01 00:00:00
abstract:Objectives:(1) To determine whether manual (MTB), or electric, tooth brushing (ETB) modulates whole salivary flow rate in older adults who are free of systemic disease. (2) To determine the duration of the brushing-related modulation of salivary flow rate. (3) To compare salivary flow rate modulation associated with MT...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3904139
更新日期:2018-02-26 00:00:00
abstract::Regulation of hematopoietic stem cell release, migration, and homing from the bone marrow (BM) and of the mobilization pathway involves a complex interaction among adhesion molecules, cytokines, proteolytic enzymes, stromal cells, and hematopoietic cells. The identification of new mechanisms that regulate the traffick...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/312656
更新日期:2013-01-01 00:00:00
abstract::Gender affirmation surgery remains one of the greatest challenges in transgender medicine. In recent years, there have been continuous discussions on bioethical aspects in the treatment of persons with gender dysphoria. Gender reassignment is a difficult process, including not only hormonal treatment with possible sur...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/9652305
更新日期:2018-06-13 00:00:00
abstract::Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/914026
更新日期:2015-01-01 00:00:00
abstract::Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/140327
更新日期:2013-01-01 00:00:00
abstract::Plant-associated bacteria provide important services to host plants. Environmental factors such as cultivar type and pedoclimatic conditions contribute to shape their diversity. However, whether these environmental factors may influence the plant growth promoting (PGP) potential of the root-associated bacteria is not ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/491091
更新日期:2013-01-01 00:00:00
abstract::Among the different signaling molecules released during reactive gliosis occurring in Alzheimer's disease (AD), the astrocyte-derived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease. The use of pharmacological tools targeting S100B may be crucial to embank its effects and some ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/508342
更新日期:2015-01-01 00:00:00
abstract::Amylase is an industrially important enzyme and applied in many industrial processes such as saccharification of starchy materials, food, pharmaceutical, detergent, and textile industries. This research work deals with the optimization of fermentation conditions for α-amylase production from thermophilic bacterial str...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9173040
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Cost sharing between beneficiaries and government is critical to attain universal health coverage. The government of Ethiopia introduced social health insurance to improve access to quality health services. Hence, HCP are the ultimate frontline service provider; their WTP for health insurance could influence...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8412957
更新日期:2020-04-14 00:00:00
abstract::Nonlinear contrast-enhanced ultrasound imaging schemes strive to suppress tissue signals in order to better visualize nonlinear signals from blood-pooling ultrasound contrast agents. Because tissue does not generate a subharmonic response (i.e., signal at half the transmit frequency), subharmonic imaging has been prop...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/640397
更新日期:2015-01-01 00:00:00