Therapeutic Effects of CUR-Activated Human Umbilical Cord Mesenchymal Stem Cells on 1-Methyl-4-phenylpyridine-Induced Parkinson's Disease Cell Model.

abstract：:Mind-body practices (MBP) are known to induce electrophysiological and morphological changes, whereas reports related to changes of neurotrophins are surprisingly scarce. Consequently, in the current paper, we focused on the Quadrato motor training (QMT), a newly developed whole-body movement-based MBP, which has been...

journal_title：BioMed research international

authors： Venditti S,Verdone L,Pesce C,Tocci N,Caserta M,Ben-Soussan TD

更新日期：2015-01-01 00:00:00

abstract：:To identify novel susceptibility genes and gene sets for obesity, we conducted a genomewide expression association analysis of obesity via integrating genomewide association study (GWAS) and expression quantitative trait loci (eQTLs) data. GWAS summary data of body mass index (BMI) and waist-to-hip ratio (WHR) was dri...

journal_title：BioMed research international

authors： Liu L,Fan Q,Zhang F,Guo X,Liang X,Du Y,Li P,Wen Y,Hao J,Wang W,He A

更新日期：2018-05-08 00:00:00

abstract：:Biliary atresia (BA) is an orphan medical condition of the newborn, resulting in end-stage liver cirrhosis due to obliterative cholangiopathy of the extrahepatic bile duct. Although Kasai's hepatoportoenterostomy (KPE) is the well-established first-line therapy, little is known about its surgical complications. 153 pa...

journal_title：BioMed research international

authors： Madadi-Sanjani O,Carl N,Longerich T,Petersen C,Andruszkow JH

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The serotonin (5-HT) pathway was shown to play a role in pulmonary hypertension (PH), but its functions in right ventricular failure (RVF) remain poorly understood. The aim of the current study was to investigate the effects of Terguride (5-HT2A and 2B receptor antagonist) or SB204741 (5-HT2B receptor antagon...

journal_title：BioMed research international

authors： Janssen W,Schymura Y,Novoyatleva T,Kojonazarov B,Boehm M,Wietelmann A,Luitel H,Murmann K,Krompiec DR,Tretyn A,Pullamsetti SS,Weissmann N,Seeger W,Ghofrani HA,Schermuly RT

更新日期：2015-01-01 00:00:00

abstract：Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...

journal_title：BioMed research international

authors： Zhang L,Song X,Li X,Wu C,Jiang J

更新日期：2018-11-14 00:00:00

abstract：:Dental modeling resins have been developed for use in areas where highly precise resin structures are needed. The manufacturers claim that these polymethyl methacrylate/methyl methacrylate (PMMA/MMA) resins show little or no shrinkage after polymerization. This study examined the polymerization shrinkage of five denta...

journal_title：BioMed research international

authors： Kwon TY,Ha JY,Chun JN,Son JS,Kim KH

更新日期：2014-01-01 00:00:00

abstract：Objective:To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods:We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combin...

journal_title：BioMed research international

authors： Xu Z,Wu Z,Zhang J,Zhou R,Wu J,Yu B

更新日期：2020-08-12 00:00:00

abstract：:This study was undertaken to evaluate the effect of 3D printed polycaprolactone (PCL)/β-tricalcium phosphate (β-TCP) scaffold containing bone demineralized and decellularized extracellular matrix (bdECM) and human recombinant bone morphogenetic protein-2 (rhBMP-2) on bone regeneration. Scaffolds were divided into PCL/...

journal_title：BioMed research international

authors： Bae EB,Park KH,Shim JH,Chung HY,Choi JW,Lee JJ,Kim CH,Jeon HJ,Kang SS,Huh JB

更新日期：2018-02-27 00:00:00

abstract：:The aim of this study was to analyze periprocedural and mid-term effect of clopidogrel on platelet function using the VerifyNow P2Y12 point-of-care assay in patients undergoing TAVI. Platelet reactivity was measured at the beginning of the procedure after 300 mg clopidogrel bolus administration and during the follow-u...

journal_title：BioMed research international

authors： Tousek P,Kocka V,Sulzenko J,Bednar F,Linkova H,Widimsky P

更新日期：2013-01-01 00:00:00

abstract：:Volatiles emitted by the host's food would be the first signals used by parasitoids in the host location process and are thought to play an important role in host habitat location. In this study, the olfactory responses of Theocolax elegans (Westwood), a Pteromalid wasp that parasitizes immature stages of stored-produ...

journal_title：BioMed research international

authors： Germinara GS,De Cristofaro A,Rotundo G

更新日期：2016-01-01 00:00:00

abstract：Background and Aims:Contrast-induced nephropathy (CIN) is a relatively infrequent complication after percutaneous coronary intervention (PCI) in patients with ST-elevation myocardial infarction (STEMI). However, little is known about the association between cytochrome c (cyt c) and increased risk of CIN. We conducted t...

journal_title：BioMed research international

authors： Tang C,Hou J,Yan G,Qiao Y,Wang D,Zhu B,Liu B,Luo E,Nawabi AQ,Chen L

更新日期：2019-01-23 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most frequent cause of chronic liver disease. NAFLD encompasses a wide range of pathologies, from simple steatosis to steatosis with inflammation to fibrosis. The pathogenesis of NAFLD progression has not been completely elucidated, and different liver cells could be imp...

journal_title：BioMed research international

authors： Almeda-Valdes P,Aguilar Olivos NE,Barranco-Fragoso B,Uribe M,Méndez-Sánchez N

更新日期：2015-01-01 00:00:00

abstract：:Age is an independent risk factor of cardiovascular disease, even in the absence of other traditional factors. Emerging evidence in experimental animal and human models has emphasized a central role for two main mechanisms of age-related cardiovascular disease: oxidative stress and inflammation. Excess reactive oxygen...

journal_title：BioMed research international

authors： Wu J,Xia S,Kalionis B,Wan W,Sun T

更新日期：2014-01-01 00:00:00

abstract：:Red blood cell distribution width (RDW) is a parameter reported in complete blood cell count tests, and has been reported as an inflammatory biomarker. Multiple myeloma (MM) is known to be associated with inflammatory microenvironments. However, the importance of RDW has been seldom studied in MM. For this study, 146 ...

journal_title：BioMed research international

authors： Lee H,Kong SY,Sohn JY,Shim H,Youn HS,Lee S,Kim HJ,Eom HS

更新日期：2014-01-01 00:00:00

abstract：:The purpose of the study is to evaluate the relationship between NIH-CPSI and IIEF-5 in Chinese men with CP/CPPS. A large cross-sectional and multicenter survey was conducted from July 2012 to January 2014. Men were recruited from urology clinics which were located at the five cities in China. All men participated in ...

journal_title：BioMed research international

authors： Gao J,Gao P,Hao Z,Zhou Z,Liu J,Li H,Xing J,Zhou Z,Deng C,Deng L,Wei Q,Zhang X,Zhou J,Fan S,Tai S,Yang C,Shi K,Huang Y,Ye Z,Liang C

更新日期：2015-01-01 00:00:00

abstract：:Secretory leukoprotease inhibitor (SLPI) is an anti-inflammatory protein present in respiratory secretions. Whilst epithelial cell SLPI is extensively studied, neutrophil associated SLPI is poorly characterised. Neutrophil function including chemotaxis and degranulation of proteolytic enzymes involves changes in cytos...

journal_title：BioMed research international

authors： Reeves EP,Banville N,Ryan DM,O'Reilly N,Bergin DA,Pohl K,Molloy K,McElvaney OJ,Alsaleh K,Aljorfi A,Kandalaft O,O'Flynn E,Geraghty P,O'Neill SJ,McElvaney NG

更新日期：2013-01-01 00:00:00

abstract：Background:DNA methylation is essential for regulating gene expression, and the changes of DNA methylation status are commonly discovered in disease. Therefore, identification of differentially methylation patterns, especially differentially methylated regions (DMRs), in two different groups is important for understand...

journal_title：BioMed research international

authors： Zhang Y,Wang S,Wang X

更新日期：2018-11-18 00:00:00

abstract：:Following cerebral ischemia/reperfusion (I/R) injury, a series of pathophysiological processes are stimulated in both the central nervous system (CNS) and the periphery, including, but not limited to, the peripheral immune and endocrine systems and underregulation of the neuroendocrine-immune network. Glutamate (Glu) ...

journal_title：BioMed research international

authors： You J,Feng L,Xin M,Ma D,Feng J

更新日期：2018-07-19 00:00:00

abstract：:Lung injury was the common and serious complication of sepsis, a systemic inflammatory response syndrome caused by severe infections. Chinese medicine had unique advantages in attenuating inflammatory response, such as Zuojinfang (ZJF). ZJF was a classical compound herb formula composed of Coptidis Rhizoma and Euodiae...

journal_title：BioMed research international

authors： Yin J,Yu Z,Hou C,Peng Y,Xiao J,Jiang J

更新日期：2021-01-06 00:00:00

abstract：:Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts. In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial re...

journal_title：BioMed research international

authors： Pradenas GA,Díaz-Vásquez WA,Pérez-Donoso JM,Vásquez CC

更新日期：2013-01-01 00:00:00

abstract：Objective:Cognitive impairment is considered to be an important complication of spinal cord injury (SCI), but its underlying mechanism remains unclear. The purpose of this study is to explore whether serum CCL21 can be used as a potential biomarker of cognitive impairment in SCI. Methods:In Neck-Shoulder and Lumbocrur...

journal_title：BioMed research international

authors： Chen Y,Liang L,Cao S,Hou G,Zhang Q,Ma H,Shi B

更新日期：2020-12-09 00:00:00

abstract：:This study documented the population dynamics of Biomphalaria and associated natural infections with digenetic trematodes, along the shores of Lake Albert and Lake Victoria, recording local physicochemical factors. Over a two-and-a-half-year study period with monthly sampling, physicochemical factors were measured at ...

journal_title：BioMed research international

authors： Rowel C,Fred B,Betson M,Sousa-Figueiredo JC,Kabatereine NB,Stothard JR

更新日期：2015-01-01 00:00:00

abstract：:The hepatoprotective and antioxidant activity of Bauhinia hookeri ethanol extract (BHE) against CCl4-induced liver injury was investigated in mice. BHE was administered (500 and 1000 mg/kg/day) along with CCl4 for 6 weeks. The hepatic marker enzymes: alanine aminotransferase (ALT), aspartate aminotransferase (AST), an...

journal_title：BioMed research international

authors： Al-Sayed E,Martiskainen O,Seif el-Din SH,Sabra AN,Hammam OA,El-Lakkany NM,Abdel-Daim MM

更新日期：2014-01-01 00:00:00

abstract：:A familiarity with the anatomy of some types of bone anomalies is necessary for clinicians involved in many medical areas. The aim of this paper is to review the newest literature concerning the morphology, embryology, clinical image, and therapeutic methods of the cervical ribs in the humans. The incidence of cervica...

journal_title：BioMed research international

authors： Spadliński Ł,Cecot T,Majos A,Stefańczyk L,Pietruszewska W,Wysiadecki G,Topol M,Polguj M

更新日期：2016-01-01 00:00:00

abstract：:A standard protocol of dosimetric measurements is used by the organizations responsible for verifying that the doses delivered in radiation-therapy institutions are within authorized limits. This study evaluated a self-designed simple auditing phantom for use in verifying the dose of radiation therapy; the phantom des...

journal_title：BioMed research international

authors： Lee JH,Chang LT,Shiau AC,Chen CW,Liao YJ,Li WJ,Lee MS,Hsu SM

更新日期：2015-01-01 00:00:00

abstract：:Introduction. Luteolin, a falconoid compound in many Chinese herbs and formula, plays important roles in cardiovascular diseases. The underlying mechanism of luteolin remains to be further elaborated. Methods. A model of hydrogen peroxide- (H2O2-) induced H9C2 cells apoptosis was established. Cell viabilities were exa...

journal_title：BioMed research international

authors： Chang H,Li C,Huo K,Wang Q,Lu L,Zhang Q,Wang Y,Wang W

更新日期：2016-01-01 00:00:00

abstract：:To investigate white matter (WM) abnormalities in neocortical epilepsy, we extract supratentorial WM parameters from raw tensor magnetic resonance images (MRI) with automated region-of-interest (ROI) registrations. Sixteen patients having neocortical seizures with secondarily generalised convulsions and 16 age-matched...

journal_title：BioMed research international

authors： Peng SJ,Harnod T,Tsai JZ,Huang CC,Ker MD,Chiou JC,Chiueh H,Wu CY,Hsin YL

更新日期：2014-01-01 00:00:00

abstract：:Our research investigates the serum levels of three angiogenic factors in the AF family, namely, placenta growth factor (PlGF), basic fibroblast growth factor (bFGF), and vascular endothelial growth factor (VEGF), in 54 patients with SLE (SLE group) and 28 healthy controls (normal control) through ELISA measurement. A...

journal_title：BioMed research international

authors： Zhou L,Lu G,Shen L,Wang L,Wang M

更新日期：2014-01-01 00:00:00

abstract：:Background. Endemic areas of tegumentary leishmaniasis (TL) in Salta, Argentina, present some overlap zones with the geographical distribution of Chagas disease, with mixed infection cases being often detected. Objectives. The purpose of this study was to determine the magnitude of Leishmania sp. infection and potenti...

journal_title：BioMed research international

authors： Hoyos CL,Cajal SP,Juarez M,Marco JD,Alberti D'Amato AM,Cayo M,Torrejón I,Cimino RO,Diosque P,Krolewiecki AJ,Nasser JR,Gil JF

更新日期：2016-01-01 00:00:00

abstract：:In previous studies, we have demonstrated the function of uc.167 in the heart development. DNA methylation plays a crucial role in regulating the expression of developmental genes during embryonic development. In this study, the methylomic landscape was investigated in order to identify the DNA methylation alterations...

journal_title：BioMed research international

authors： Yin A,Feng M,Cheng Z,Zhang Q,Li H,Xu J,Zhang H,Li Y,Qian L

更新日期：2018-05-30 00:00:00