The Role of Dendritic Cells in Fibrosis Progression in Nonalcoholic Fatty Liver Disease.

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00

abstract：:Introduction. The aim of this study was to investigate the utility of ultrasonography (US) for predicting and assessing the effectiveness of extracorporeal shock wave therapy (ESWT) in insertional Achilles tendinopathy (IAT). Methods. A total of 42 patients with an established diagnosis of chronic IAT were examined by...

journal_title：BioMed research international

authors： Cheng Y,Zhang J,Cai Y

更新日期：2016-01-01 00:00:00

abstract：Background:Long noncoding RNAs (lncRNAs) play a crucial role in varieties of biological processes. This study is aimed at investigating meniscal degeneration-specific lncRNAs and mRNAs and their related networks in knee osteoarthritis (KOA). Methods:The dataset GSE98918, which included 24 meniscus samples and related ...

journal_title：BioMed research international

authors： Zhao J,Su Y,Jiao J,Wang Z,Fang X,He X,Zhang X,Liu Z,Xu X

更新日期：2020-05-20 00:00:00

abstract：:The development of multitargeting drugs is an emerging trend in cancer research. To promote further development and clinical application of multitargeting drugs, this research was performed. MTT assay and flow cytometry of Annexin V/propidium iodide staining were used to confirm the proapoptotic efficacy of a novel co...

journal_title：BioMed research international

authors： Zheng H,Liang G,Chen Y,Lin S,Liu W,Fang Y

更新日期：2017-01-01 00:00:00

abstract：:The relationship between diabetes mellitus (DM) and Alzheimer's disease (AD) has attracted wide attention. Studies have reported that ginsenoside Rb1 can improve human cognitive ability and glucose tolerance during the development of diabetes. The mechanism behind the improvement in cognitive ability and glucose toler...

journal_title：BioMed research international

authors： Yang R,Jiang X,He X,Liang D,Sun S,Zhou G

更新日期：2020-05-20 00:00:00

abstract：Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

journal_title：BioMed research international

authors： Jin X,Niu Y,Gu W,Wang J

更新日期：2020-08-10 00:00:00

abstract：Background:Thyroid cancer is the most common endocrine malignancy, with a recent global increase of 20% in age-related incidence. Ultrasonography and ultrasonography-guided fine-needle aspiration biopsy (FNAB) are the most widely used diagnostic tests for thyroid nodules; however, it is estimated that up to 25% of thyr...

journal_title：BioMed research international

authors： Nan BY,Xiong GF,Zhao ZR,Gu X,Huang XS

更新日期：2021-01-12 00:00:00

abstract：Background:Strongyloidiasis is an intestinal parasitic infection mainly caused by Strongyloides stercoralis. Although it is a predominant parasite in tropics and subtropics where sanitation and hygiene are poorly practiced, the true prevalence of strongyloidiasis is not known due to low-sensitivity diagnostic methods. ...

journal_title：BioMed research international

authors： Hailu T,Nibret E,Amor A,Munshea A

更新日期：2020-11-15 00:00:00

abstract：:Due to expanding applications of positron emission tomography (PET) there is a demand for developing new techniques to introduce fluorine-18 (t 1/2 = 109.8 min). Considering that most novel PET tracers are sensitive biomolecules and that direct introduction of fluorine-18 often needs harsh conditions, the insertion of...

journal_title：BioMed research international

authors： Kettenbach K,Schieferstein H,Ross TL

更新日期：2014-01-01 00:00:00

abstract：:The objective and quantitative analysis of longitudinal single photon emission computed tomography (SPECT) images are significant for the treatment monitoring of brain disorders. Therefore, a computer aided analysis (CAA) method is introduced to extract a change-rate map (CRM) as a parametric image for quantifying the...

journal_title：BioMed research international

authors： Zheng X,Wei W,Huang Q,Song S,Wan J,Huang G

更新日期：2017-01-01 00:00:00

abstract：:Bacterial biofilms are communities of microorganisms attached to a surface. Biofilm formation is critical not only for environmental survival but also for successful infection. Helicobacter pylori is one of the most common causes of bacterial infection in humans. Some studies demonstrated that this microorganism has b...

journal_title：BioMed research international

authors： Yonezawa H,Osaki T,Kamiya S

更新日期：2015-01-01 00:00:00

abstract：:Viscosupplementation with hyaluronic acid is safe and effective in the management of osteoarthritis, but its use in the treatment of tendon disorders has received less attention. The aim of this review is to summarize the current knowledge on this topic, evaluating experimental and clinical trials. A search of English...

journal_title：BioMed research international

authors： Abate M,Schiavone C,Salini V

更新日期：2014-01-01 00:00:00

abstract：:The aims of this study were to investigate the reasons of transfers from long-term care hospitals (LTCHs) to emergency departments (EDs) of university hospitals in geriatric patients and to categorize the avoidable causes of these transfers. This retrospective multicenter study involved patients aged 65 years and olde...

journal_title：BioMed research international

authors： Kim K,Lee DH,Yune HY,Wee JH,Kim DH,Kim EC,Lim JY,Choi SP

更新日期：2019-06-19 00:00:00

abstract：:The nonnucleoside reverse transcriptase inhibitors, used for the treatment of HIV infections, are reported to have low bioavailability pertaining to high first-pass metabolism, high protein binding, and enzymatic metabolism. They also show low permeability across blood brain barrier. The CNS is reported to be the most...

journal_title：BioMed research international

authors： Gupta S,Kesarla R,Chotai N,Misra A,Omri A

更新日期：2017-01-01 00:00:00

abstract：:Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...

journal_title：BioMed research international

authors： Farini A,Sitzia C,Erratico S,Meregalli M,Torrente Y

更新日期：2014-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：:Tryptophan (Trp) plays an essential role in pig behavior and growth performances. However, little is known about Trp's effects on tight junction barrier and intestinal health in weaned pigs. In the present study, twenty-four (24) weaned pigs were randomly assigned to one of the three treatments with 8 piglets/treatmen...

journal_title：BioMed research international

authors： Tossou MC,Liu H,Bai M,Chen S,Cai Y,Duraipandiyan V,Liu H,Adebowale TO,Al-Dhabi NA,Long L,Tarique H,Oso AO,Liu G,Yin Y

更新日期：2016-01-01 00:00:00

abstract：:Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternatives for blocking th...

journal_title：BioMed research international

authors： Sánchez-Barinas CD,Ocampo M,Tabares L,Bermúdez M,Patarroyo MA,Patarroyo ME

更新日期：2019-04-14 00:00:00

abstract：:Background. Genome-wide association studies (GWAS) have shown its revolutionary power in seeking the influenced loci on complex diseases genetically. Thousands of replicated loci for common traits are helpful in diseases risk assessment. However it is still difficult to elucidate the variations in these loci that dire...

journal_title：BioMed research international

authors： Ma LX,Wang YJ,Wang JF,Li X,Hao P

更新日期：2013-01-01 00:00:00

abstract：:Postoperative cognitive dysfunction (POCD) is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expre...

journal_title：BioMed research international

authors： Zhang Y,Lin Y,Liu Q,Yuan X,Mao A,Liu Y,Li Q,Zheng J,Hu B,Yu F

更新日期：2018-01-16 00:00:00

abstract：Background:The use of modern family planning methods among women of reproductive age (15-49 years) is of public health importance in Ethiopia. Nationally, modern family planning method use remains as low as 35%. Understanding factors associated with the use of modern family planning methods may help to improve maternal...

journal_title：BioMed research international

authors： Mulatu T,Sintayehu Y,Dessie Y,Deressa M

更新日期：2020-12-29 00:00:00

abstract：Purpose:To explore the effects of depression on cardiac autonomic nerve function and related metabolic pathways, the heart rate variability (HRV) and urinary differential metabolites were detected on the college students with depression. Methods:12 female freshmen with depression were filtered by the Beck Depression I...

journal_title：BioMed research international

authors： Zhao S,Chi A,Yan J,Yao C

更新日期：2020-02-27 00:00:00

abstract：:The main aim was to analyse the associations between several physical fitness variables and bone parameters in a sample of elderly people. 129 participants (94 females and 35 males, 76.2 ± 5.4 y) from the EXERNET cohort of Zaragoza (Spain) were included in the study. Physical fitness was assessed using the Senior Fitn...

journal_title：BioMed research international

authors： Moradell A,Gómez-Cabello A,Gómez-Bruton A,Muniz-Pardos B,Puyalto JM,Matute-Llorente A,Gónzalez-Agüero A,Ara I,Casajús JA,Vicente-Rodríguez G

更新日期：2020-07-15 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone destruction in RA. Ho...

journal_title：BioMed research international

authors： Song J,Liu H,Zhu Q,Miao Y,Wang F,Yang F,Cheng W,Xi Y,Niu X,He D,Chen G

更新日期：2018-02-19 00:00:00

abstract：:The receptor activator of NF-κB (RANK) pathway is involved in bone health as well as breast cancer (BC) pathogenesis and progression. Whereas the therapeutic implication of this pathway is established for the treatment of osteoporosis and bone metastases, the application in adjuvant BC is currently investigated. As ge...

journal_title：BioMed research international

authors： Hein A,Bayer CM,Schrauder MG,Häberle L,Heusinger K,Strick R,Ruebner M,Lux MP,Renner SP,Schulz-Wendtland R,Ekici AB,Hartmann A,Beckmann MW,Fasching PA

更新日期：2014-01-01 00:00:00

abstract：:Preformulation is an important step in the rational formulation of an active pharmaceutical ingredient (API). Micromeritics properties: bulk density (BD) and tapped density (TD), compressibility index (Carr's index), Hauser's ratio (H), and sieve analysis were performed in order to determine the best excipients to be ...

journal_title：BioMed research international

authors： Migoha CO,Ratansi M,Kaale E,Kagashe G

更新日期：2015-01-01 00:00:00

abstract：:Introduction and Objectives. Neutrophil-to-lymphocyte ratio (NLR) has been suggested to be a simple marker of the systemic inflammatory response in critical care patients. We previously assessed the utility of NLR as a biomarker to predict tumor recurrence and cancer death in bladder cancer patients who underwent radi...

journal_title：BioMed research international

authors： Ohtake S,Kawahara T,Kasahara R,Ito H,Osaka K,Hattori Y,Teranishi JI,Makiyama K,Mizuno N,Umemoto S,Miyoshi Y,Nakaigawa N,Miyamoto H,Yao M,Uemura H

更新日期：2016-01-01 00:00:00

abstract：:Recently, cardiovascular disease, also known as loop circulatory system diseases or disorders, is one of the serious diseases including heart disease, stroke, atherosclerosis, myocardial infarction, hypertension, hypotension, and thrombosis. Human pregnane X receptor, PXR, plays a crucial role in exogenous and endobio...

journal_title：BioMed research international

authors： Chen KB,Chen HY,Chen KC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：Introduction:The incidence of acute kidney injury (AKI) considerably increases the mortality rate in polytrauma victims. Undoubtedly, early identification of patients at risk is crucial for timely implementation of preventive strategies in order to improve their prognosis. Therefore, we aimed to investigate if serum ne...

journal_title：BioMed research international

authors： Negrin LL,Hahn R,Heinz T,Hajdu S

更新日期：2018-11-06 00:00:00

abstract：:Rapid bone defect filling with normal bone is a challenge in orthopaedics and dentistry. Strontium ranelate (SrRan) has been shown to in vitro decrease bone resorption and increase bone formation, and represents a potential agent with the capacity to accelerate bone defect filling. In this study, bone tibial defects o...

journal_title：BioMed research international

authors： Zacchetti G,Dayer R,Rizzoli R,Ammann P

更新日期：2014-01-01 00:00:00