The Effect of Dexmedetomidine on Cognitive Function and Protein Expression of Aβ, p-Tau, and PSD95 after Extracorporeal Circulation Operation in Aged Rats.

abstract：:A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...

journal_title：BioMed research international

authors： Rong E,Wang H,Hao S,Fu Y,Ma Y,Wang T

更新日期：2018-11-13 00:00:00

abstract：:The role of nitric oxide and its reactive derivatives (NO x ) is well known in the pathogenesis of multiple sclerosis, which is an inflammatory disease while NO x seems to be important in coordinating inflammatory response. The...

journal_title：BioMed research international

authors： Niedziela N,Adamczyk-Sowa M,Niedziela JT,Mazur B,Kluczewska E,Sowa P,Gąsior M

更新日期：2016-01-01 00:00:00

abstract：:Metabolomics is the sophisticated and high-throughput technology based on the entire set of metabolites which is known as the connector between genotypes and phenotypes. For any phenotypic changes, potential metabolite (biomarker) identification is very important because it provides diagnostic as well as prognostic ma...

journal_title：BioMed research international

authors： Kumar N,Hoque MA,Shahjaman M,Islam SM,Mollah MN

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Parents' birth weight acts as a predictor for the descendant birth weight, with the correlation more strongly transmitted through maternal line. The present research aims to study the correlation between the child's low or increased birth weight, the mother's birth weight, and maternal conditi...

journal_title：BioMed research international

authors： Costa e Silva LI,Gomes FM,Valente MH,Escobar AM,Brentani AV,Grisi SJ

更新日期：2015-01-01 00:00:00

abstract：:The purpose of the study is to evaluate the relationship between NIH-CPSI and IIEF-5 in Chinese men with CP/CPPS. A large cross-sectional and multicenter survey was conducted from July 2012 to January 2014. Men were recruited from urology clinics which were located at the five cities in China. All men participated in ...

journal_title：BioMed research international

authors： Gao J,Gao P,Hao Z,Zhou Z,Liu J,Li H,Xing J,Zhou Z,Deng C,Deng L,Wei Q,Zhang X,Zhou J,Fan S,Tai S,Yang C,Shi K,Huang Y,Ye Z,Liang C

更新日期：2015-01-01 00:00:00

abstract：:Solid lipid nanoparticle is an efficient lipid based drug delivery system which can enhance the bioavailability of poorly water soluble drugs. Efavirenz is a highly lipophilic drug from nonnucleoside inhibitor category for treatment of HIV. Present work illustrates development of an SLN formulation for Efavirenz with ...

journal_title：BioMed research international

authors： Gaur PK,Mishra S,Bajpai M,Mishra A

更新日期：2014-01-01 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) is one of the most common cancers in the world. Our aim is to identify prognostic biomarkers that contribute to the progression of early stage ccRCC and clarify the mechanism. Here, the mRNA microarray expression profile of ccRCC samples was obtained from Gene Expression Omnibus...

journal_title：BioMed research international

authors： Qiu X,Gu Y,Ni Y,Li Q

更新日期：2020-10-29 00:00:00

abstract：:Nowadays, a growing number of young and more active patients receive hip replacement. More strenuous activities in such patients involve higher friction and wear rates, with friction on the bearing surface being crucial to ensure arthroplasty survival in the long term. Over the last years, the polycarbonate-urethane h...

journal_title：BioMed research international

authors： Gabarre S,Herrera A,Mateo J,Ibarz E,Lobo-Escolar A,Gracia L

更新日期：2014-01-01 00:00:00

abstract：Background:The reliability of blood pressure (BP) measurement in hospitalized patients is a topic of debate and the therapeutic implication of the routinely collected BP profiles is probably overestimated. When measurements are performed in elderly patients, further potential sources of misinterpretation occur. Method...

journal_title：BioMed research international

authors： Del Giorno R,Heiniger PS,Balestra L,Gabutti L

更新日期：2019-04-01 00:00:00

abstract：:The increased use of imaging modalities in the last years has led to a greater incidence in depicting abdominal incidental lesions. In particular, "incidentalomas" of the kidney are discovered in asymptomatic patients or patients who suffer from diseases not directly related to the kidneys. The aim of this paper is to...

journal_title：BioMed research international

authors： Mazziotti S,Cicero G,D'Angelo T,Marino MA,Visalli C,Salamone I,Ascenti G,Blandino A

更新日期：2017-01-01 00:00:00

abstract：Objective:The objective was to study the risk and protective factors involved in retinal vascular development of preterm infants with retinopathy of prematurity. Methods:Between 2000 and 2017, 185 preterm infants were included in the protocol for retinopathy of prematurity. Risk factors associated with speed of retina...

journal_title：BioMed research international

authors： Solans Pérez de Larraya AM,Ortega Molina JM,Uberos Fernández J,González Ramírez AR,García Serrano JL

更新日期：2019-04-24 00:00:00

abstract：:The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5'-hydroxy auraptene (5'-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stimulator for osteobla...

journal_title：BioMed research international

authors： Abdallah BM,Ali EM,Elsawy H,Badr GM,Abdel-Moneim AM,Alzahrani AM

更新日期：2019-12-28 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/8094152.]. ...

journal_title：BioMed research international

authors： Xie Y,Su Y,Min S,Tang J,Goh BT,Saigo L,Ansari S,Moshaverinia A,Zhang C,Wang J,Liu Y,Khojasteh A,Zadeh HH,Wang S

更新日期：2017-01-01 00:00:00

abstract：:The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...

journal_title：BioMed research international

authors： Martínez-Torteya A,Treviño V,Tamez-Peña JG

更新日期：2015-01-01 00:00:00

abstract：:Both human adipose tissue-derived mesenchymal stem cells (ASCs) and umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been explored as attractive mesenchymal stem cells (MSCs) sources, but very few parallel comparative studies of these two cell types have been made. We designed a side-by-side comparative st...

journal_title：BioMed research international

authors： Hu L,Hu J,Zhao J,Liu J,Ouyang W,Yang C,Gong N,Du L,Khanal A,Chen L

更新日期：2013-01-01 00:00:00

abstract：:Medicinal plants have played an important role in the treatment of many diseases. Medicinal plants are believed to be well appropriate with the human body and to produce less side influences than the pharmaceuticals. Kingdom of Saudi Arabia has abundant and wide variety of medicinal plants whose therapeutic effects ha...

journal_title：BioMed research international

authors： Almalki DA,Alghamdi SA,Al-Attar AM

更新日期：2019-02-27 00:00:00

abstract：UNLABELLED:The aim of this study was to evaluate the relation between the sensory and anthropometric variables in the quiet standing. METHODS:One hundred individuals (50 men, 50 women; 20-40 years old) participated in this study. For all participants, the body composition (fat tissue, lean mass, bone mineral content, ...

journal_title：BioMed research international

authors： Alonso AC,Mochizuki L,Silva Luna NM,Ayama S,Canonica AC,Greve JM

更新日期：2015-01-01 00:00:00

abstract：:Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza Bunge, has shown an antiproliferative activity on various human cancer cell lines including nasopharyngeal carcinoma cells. However, the effects of Tan IIA on human oral cancer cells are still unknown. This study aimed to invest...

journal_title：BioMed research international

authors： Tseng PY,Lu WC,Hsieh MJ,Chien SY,Chen MK

更新日期：2014-01-01 00:00:00

abstract：Background:Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ALCF) is a complicated syndrome with extremely high short-term mortality. The artificial liver support system (ALSS) may improve the liver function for patients with HBV-ACLF, but the data on its short-term outcomes are insufficient in China. ...

journal_title：BioMed research international

authors： Xiao LL,Xu XW,Huang KZ,Zhao YL,Zhang LJ,Li LJ

更新日期：2019-11-29 00:00:00

abstract：Purpose:This study aims to compare the functional outcomes of nonunion humeral diaphyseal fractures following conservative treatment when managed surgically with either a plate or intramedullary (IM) nail fixation. Methods:This was a retrospective study of 56 patients with nonunion humeral fractures following conserva...

journal_title：BioMed research international

authors： Micic I,Kholinne E,Kwak JM,Sun Y,Nanda A,Kim H,Koh KH,Jeon IH

更新日期：2019-07-22 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to detect the inhibitory action of the early growth response gene-1 DNA enzyme (EDRz) as a carrying agent by liposomes on vascular smooth muscle cell proliferation and intimal hyperplasia. An autogenous vein graft model was established. EDRz was transfected to the graft vein. The vein graft s...

journal_title：BioMed research international

authors： Liu C,Zhang X,Wang S,Cheng M,Liu C,Wang S,Hu X,Zhang Q

更新日期：2013-01-01 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00

abstract：Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...

journal_title：BioMed research international

authors： Zhao Y,Song YQ,Gao J,Feng SY,Li Y

更新日期：2019-07-15 00:00:00

abstract：:Polyetheretherketone (PEEK), which has biomechanical performance similar to that of human cancellous bone, is used widely as a spinal implant material. However, its bioinertness and hydrophobic surface properties result in poor osseointegration. This study applies a novel modification method, arc ion plating (AIP), th...

journal_title：BioMed research international

authors： Tsou HK,Chi MH,Hung YW,Chung CJ,He JL

更新日期：2015-01-01 00:00:00

abstract：:The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...

journal_title：BioMed research international

authors： Agarwal SK,Foster WG

更新日期：2015-01-01 00:00:00

abstract：:Introduction. In the field of orthopaedic surgery, the use of osteogenic material in larger defects is essential. Autograft and allograft are both known methods, and autograft is believed to be the best choice. But autograft is associated with additional invasive procedures which can prove difficult in fragile patient...

journal_title：BioMed research international

authors： Dreyer CH,Rasmussen M,Pedersen RH,Overgaard S,Ding M

更新日期：2020-03-03 00:00:00

abstract：:Mexico has one of the highest incidences of childhood leukemia worldwide and significantly higher mortality rates for this disease compared with other countries. One possible cause is the high prevalence of gene rearrangements associated with the etiology or with a poor prognosis of childhood acute lymphoblastic leuke...

journal_title：BioMed research international

authors： Bekker-Méndez VC,Miranda-Peralta E,Núñez-Enríquez JC,Olarte-Carrillo I,Guerra-Castillo FX,Pompa-Mera EN,Ocaña-Mondragón A,Rangel-López A,Bernáldez-Ríos R,Medina-Sanson A,Jiménez-Hernández E,Amador-Sánchez R,Peñaloza-González JG,

更新日期：2014-01-01 00:00:00

abstract：:RAW264.7 is a macrophage strain derived from mice tumour and shows a significant ability in antigen uptake. Real-time quantitative PCR (RT-qPCR) is one of the most commonly used methods in gene studies and requires suitable reference genes to normalize and quantitate the expression of gene of interest with sensitivity...

journal_title：BioMed research international

authors： Bao Z,Huang Y,Chen J,Wang Z,Qian J,Xu J,Zhao Y

更新日期：2019-05-16 00:00:00

abstract：:Aerobic granulation of activated sludge was successfully achieved in a full-scale sequencing batch reactor (SBR) with 50,000 m(3) d(-1) for treating a town's wastewater. After operation for 337 days, in this full-scale SBR, aerobic granules with an average SVI30 of 47.1 mL g(-1), diameter of 0.5 mm, and settling veloc...

journal_title：BioMed research international

authors： Li J,Ding LB,Cai A,Huang GX,Horn H

更新日期：2014-01-01 00:00:00