Protective Effect of Zuojin Fang on Lung Injury Induced by Sepsis through Downregulating the JAK1/STAT3 Signaling Pathway.

abstract：:Excessive ethanol consumption is one of the main causes of liver fibrosis. However, direct effects of ethanol exposure on endothelial cells and their contribution to fibrogenesis and metastasis were not investigated. Therefore we analysed whether ethanol directly affects endothelial cells and if this plays a role duri...

journal_title：BioMed research international

authors： Raskopf E,Gonzalez Carmona MA,Van Cayzeele CJ,Strassburg C,Sauerbruch T,Schmitz V

更新日期：2014-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. JAK/STAT signalling pathway is involved in autoimmune diseases and in the atherosclerotic process. JAK3 is a highly promising target for immunomodulatory drugs and polymorphisms in ...

journal_title：BioMed research international

authors： García-Bermúdez M,López-Mejías R,Genre F,Castañeda S,Corrales A,Llorca J,González-Juanatey C,Ubilla B,Miranda-Filloy JA,Pina T,Gómez-Vaquero C,Rodríguez-Rodríguez L,Fernández-Gutiérrez B,Balsa A,Pascual-Salcedo D,López-Long

更新日期：2015-01-01 00:00:00

abstract：Background:Though there are several prognostic models, there is no protein-related prognostic model. The aim of this study is to identify possible prognostic-related proteins in bladder urothelial carcinoma and to try to predict the prognosis of bladder urothelial carcinoma based on these proteins. Methods:Profile dat...

journal_title：BioMed research international

authors： Luo Q,Zhang X

更新日期：2020-07-31 00:00:00

abstract：:A dentin-cement-prosthesis complex restored with either all-porcelain, cured resin-composite, or cast base metal alloy and cemented with either of the different resin cements was trimmed into a mini-dumbbell shape for tensile testing. The fractured surfaces and characterization of the dentin-cement interface of bonded...

journal_title：BioMed research international

authors： Piemjai M,Nakabayashi N

更新日期：2015-01-01 00:00:00

abstract：:Vitamin D deficiency is common in pregnant women and infants. The present study aimed to investigate the effects of vitamin D restricted diet on the Wistar rats offspring penis morphology. Mother rats received either standard diet (SC) or vitamin D restricted (VitD) diet. At birth, offspring were divided into SC/SC (f...

journal_title：BioMed research international

authors： Fernandes-Lima F,Gregório BM,Nascimento FAM,Costa WS,Gallo CBM,Sampaio FJB

更新日期：2018-04-23 00:00:00

abstract：:Lung cancer consists of two main subtypes: small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) that are classified according to their physiological phenotypes. In this study, we have developed a network-based approach to identify molecular biomarkers that can distinguish SCLC from NSCLC. By identifyin...

journal_title：BioMed research international

authors： Long F,Su JH,Liang B,Su LL,Jiang SJ

更新日期：2015-01-01 00:00:00

abstract：Introduction:An increased number of survivors have emerged from the 2014 West African Ebola Virus Disease (EVD) epidemic. Post-Ebola Syndrome (PES) is a group of physical and psychological symptoms affecting EVD survivors. This study aimed to estimate the prevalence of PES among EVD survivors in Montserrado County, Lib...

journal_title：BioMed research international

authors： Wilson HW,Amo-Addae M,Kenu E,Ilesanmi OS,Ameme DK,Sackey SO

更新日期：2018-06-28 00:00:00

abstract：PURPOSE:The primary aim of this study was to explore if classification, whether using the BI-RADS categories based on CEUS or conventional ultrasound, was conducive to the identification of benign and malignant category 3 or 4 small breast lesions. MATERIAL AND METHODS:We evaluated 30 malignant and 77 benign small bre...

journal_title：BioMed research international

authors： Zhang JX,Cai LS,Chen L,Dai JL,Song GH

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Recovery of walking outdoors after hip fracture is important for equal participation in the community. The causes of poor recovery are not fully understood. This study investigates recovery of walking outdoors and associated determinants after hip fracture. METHODS:A prospective follow-up study, among clinical...

journal_title：BioMed research international

authors： Salpakoski A,Törmäkangas T,Edgren J,Sihvonen S,Pekkonen M,Heinonen A,Pesola M,Kallinen M,Rantanen T,Sipilä S

更新日期：2014-01-01 00:00:00

abstract：:Tankyrase (TNKS) plays important roles in the malignancy of several cancers such as human lung tumor, breast cancer, and hepatocellular cancer. However, its exact functions and molecular mechanisms in ovarian cancer remain unclear. In this study, we found that TNKS was aberrantly overexpressed in human ovarian cancer ...

journal_title：BioMed research international

authors： Yang HY,Shen JX,Wang Y,Liu Y,Shen DY,Quan S

更新日期：2019-02-20 00:00:00

abstract：Objective:To investigate the effects of arteriovenous thrombolysis combined with mechanical thrombectomy on clinical efficacy, neurological function, and the changes of nerve injury markers of acute cerebral infarct (ACI) patients. Methods:A total of 143 cases with ACI admitted to our hospital from June 2017 to June 2...

journal_title：BioMed research international

authors： Ding T,Tang L,Hu B,Yuan J,Li X,Wen J

更新日期：2020-10-09 00:00:00

abstract：:The regiospecific distribution of fatty acids (FAs) and composition of triglyceride (TAG) molecular species of fishes were analyzed and calculated by pancreatic lipase (PL) hydrolysis and Visual Basic (VB) program. DHA was preferentially located at sn-2 position in TAG molecule, whereas EPA was almost equally distribu...

journal_title：BioMed research international

authors： Zhang H,Shen Y,Zhang Y,Li L,Wang X

更新日期：2018-01-29 00:00:00

abstract：:The white-rot fungus Phanerochaete chrysosporium was investigated for its capacity to degrade the herbicide diuron in liquid stationary cultures. The presence of diuron increased the production of lignin peroxidase in relation to control cultures but only barely affected the production of manganese peroxidase. The her...

journal_title：BioMed research international

authors： Coelho-Moreira Jda S,Bracht A,de Souza AC,Oliveira RF,de Sá-Nakanishi AB,de Souza CG,Peralta RM

更新日期：2013-01-01 00:00:00

abstract：:Accurate definition and better understanding of the mechanisms of stroke are crucial as this will guide the effective care and therapy. In this paper, we review the previous basic and clinical researches on the causes or mechanisms of ischemic cerebrovascular diseases (ICVD) and interpret the correlation between embol...

journal_title：BioMed research international

authors： Yu YP,Tan L

更新日期：2016-01-01 00:00:00

abstract：:Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Emba...

journal_title：BioMed research international

authors： Song X,Qu H,Yang Z,Rong J,Cai W,Zhou H

更新日期：2017-01-01 00:00:00

abstract：Background:Long noncoding RNAs (lncRNAs) play a crucial role in varieties of biological processes. This study is aimed at investigating meniscal degeneration-specific lncRNAs and mRNAs and their related networks in knee osteoarthritis (KOA). Methods:The dataset GSE98918, which included 24 meniscus samples and related ...

journal_title：BioMed research international

authors： Zhao J,Su Y,Jiao J,Wang Z,Fang X,He X,Zhang X,Liu Z,Xu X

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:It is well established that the Mediterranean and Arab populations are at high risk for thalassemias in general and for alpha-thalassemia in particular. Yet, reports on alpha-thalassemia in Lebanon are still lacking. In this study, we aim at assessing the incidence of alpha-thalassemia in the Lebanese popula...

journal_title：BioMed research international

authors： Farra C,Daher R,Badra R,el Rafei R,Bejjany R,Charafeddine L,Yunis K

更新日期：2015-01-01 00:00:00

abstract：Background:The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. Methods:We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected with ferric ammonium ci...

journal_title：BioMed research international

authors： Xu W,Yu R,Zhu X,Li Z,Jia J,Li D,Chen Y,Zhang X

更新日期：2020-05-24 00:00:00

abstract：:ADP-glucose pyrophosphorylase (AGPase) is the first rate limiting enzyme of starch biosynthesis pathway and has been exploited as the target for greater starch yield in several plants. The structure-function analysis and substrate binding specificity of AGPase have provided enormous potential for understanding the rol...

journal_title：BioMed research international

authors： Sarma K,Sen P,Barooah M,Choudhury MD,Roychoudhury S,Modi MK

更新日期：2014-01-01 00:00:00

abstract：:The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of developing PD in certa...

journal_title：BioMed research international

authors： Gopalai AA,Lim SY,Chua JY,Tey S,Lim TT,Mohamed Ibrahim N,Tan AH,Eow GB,Abdul Aziz Z,Puvanarajah SD,Viswanathan S,Looi I,Lim SK,Tan LP,Chong YB,Tan CT,Zhao Y,Tan EK,Ahmad-Annuar A

更新日期：2014-01-01 00:00:00

abstract：Design:From July 2016 to June 2018, 36 women with symptomatic early pregnancy around 4-8 weeks of gestation were recruited into the study. Among them, there were 16 women with viable intrauterine pregnancy (VIP), 9 women with spontaneous abortion (SA), and 11 women of EP. Serum exosomal miRNAs were extracted and measur...

journal_title：BioMed research international

authors： Sun J,Deng G,Ruan X,Chen S,Liao H,Liu X,Li J,Zhao G,Gao J

更新日期：2020-06-11 00:00:00

abstract：:Because of their high incidence and mortality solid cancers are a major health problem worldwide. Although several new biomarkers and potential targets for therapy have been identified through biomolecular research in the last years, the effects on patients' outcome are still unsatisfactory. Increasing evidence indica...

journal_title：BioMed research international

authors： Lastraioli E,Lottini T,Bencini L,Bernini M,Arcangeli A

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The deregulated tumorigenic long non-coding RNA (lncRNA) has been reported in several malignancies. However, there is still no comprehensive study on tongue squamous cell carcinoma (SCC). METHODS:Functional reannotation for the human lncRNA was carried out by ncFANs. Real-time quantitative PCR was used to v...

journal_title：BioMed research international

authors： Gao W,Chan JY,Wong TS

更新日期：2014-01-01 00:00:00

abstract：:This study aims to investigate the expression of macrophage inflammatory protein-3 alpha (MIP-3α) and cystatin A in nasopharyngeal carcinoma (NPC) and their association with clinical characteristics and prognosis. Primary tumor specimens from 114 NPC patients and associated clinical follow-up data were collected, and ...

journal_title：BioMed research international

authors： Tang M,Ou N,Li C,Lu A,Li J,Ma L,Zhong W,Gao J,Zheng Y,Cai Y

更新日期：2015-01-01 00:00:00

abstract：:Stressful events can have both short- and long-term effects on the brain. Our recent investigation identified short-term white matter integrity (WMI) changes in 30 subjects soon after the Japanese earthquake. Our findings suggested that lower WMI in the right anterior cingulum (Cg) was a pre-existing vulnerability fac...

journal_title：BioMed research international

authors： Sekiguchi A,Kotozaki Y,Sugiura M,Nouchi R,Takeuchi H,Hanawa S,Nakagawa S,Miyauchi CM,Araki T,Sakuma A,Taki Y,Kawashima R

更新日期：2014-01-01 00:00:00

abstract：:We evaluated whether the timing of maternal hypoxia during pregnancy influenced cardiac extracellular matrix accumulation in the adult offspring. Rats in different periods of pregnancy were assigned to maternal hypoxia or control groups. Maternal hypoxia from day 3 to 21 of pregnancy or day 9 to 21 of pregnancy increa...

journal_title：BioMed research international

authors： Wang L,Li M,Huang Z,Wang Z

更新日期：2014-01-01 00:00:00

abstract：:After earthquakes, continuing dialysis for patients with ESRD and patients suffering from crush syndrome is the serious problem. In this paper, we analyzed the failure of the provision of dialysis services observed in recent disasters and discussed how to prepare for disasters to continue dialysis therapy. Japan has f...

journal_title：BioMed research international

authors： Ikegaya N,Seki G,Ohta N

更新日期：2016-01-01 00:00:00

abstract：:Background. Antitumor necrosis factor (anti-TNF) drugs have been applied for rheumatoid arthritis (RA) treatment; however, patients having anti-drug antibodies (ADAbs) do not benefit from these drugs. The meta-analysis aims to comprehensively assess the relationship between ADAb positive (ADAb+) and anti-TNF response ...

journal_title：BioMed research international

authors： Wu C,Wang S,Xian P,Yang L,Chen Y,Mo X

更新日期：2016-01-01 00:00:00

abstract：:Professional phagocytic cells, such as dendritic cells, are mainly responsible for phagocytosis, antigen presentation, and cytokine secretion, which induce subsequent activation of T cell-mediated immunity. Thus, strategies that deliver antigens and stimulatory signals to the cells have significant implications for va...

journal_title：BioMed research international

authors： Kojima N,Ishii M,Kawauchi Y,Takagi H

更新日期：2013-01-01 00:00:00

abstract：:So far, there is no report regarding the micro-Raman vibrational fingerprint of the bonds between 10-methacryloyloxy-decyl dihydrogen phosphate (10-MDP) and zirconia ceramics. Thus, the aim of this study was to identify the Raman vibrational peaks related to the bonds of 10-MDP with zirconia, as well as the influence ...

journal_title：BioMed research international

authors： De-Paula DM,Loguercio AD,Reis A,Frota NM,Melo R,Yoshihara K,Feitosa VP

更新日期：2017-01-01 00:00:00