Efficacy and Safety of L-Carnitine Treatment for Chronic Heart Failure: A Meta-Analysis of Randomized Controlled Trials.

abstract：:Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices. Measuring TFA is an arduous task because of the need for fat biopsies. This study identifies a...

journal_title：BioMed research international

authors： Abraham RA,Bahl VK,Parshad R,Seenu V,Roy A,Golandaz S,Dorairaj P,Ramakrishnan L

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The genome-wide association studies (GWAS) have been successful during the last few years. A key challenge is that the interpretation of the results is not straightforward, especially for transacting SNPs. Integration of transcriptome data into GWAS may provide clues elucidating the mechanisms by which a gen...

journal_title：BioMed research international

authors： Jiang G,Chakraborty A,Wang Z,Boustani M,Liu Y,Skaar T,Li L

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl2 on autophagy and muscle atrophy are still unclear. METHODS:C2C12 myotubes were exposed to increasing concentrat...

journal_title：BioMed research international

authors： Chen R,Jiang T,She Y,Xu J,Li C,Zhou S,Shen H,Shi H,Liu S

更新日期：2017-01-01 00:00:00

abstract：:Recently, an important topic of the acquired immunodeficiency syndrome (AIDS) had been published in 2013. In this report, the expression of the IFN-induced myxovirus resistance 2 (MX2) had been defined the function to kill the human immunodeficiency virus (HIV). The screening from the Traditional Chinese Medicine (TCM...

journal_title：BioMed research international

authors： Hung TC,Lee WY,Chen KB,Chan YC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:In esophageal squamous cell carcinoma, an elevated preoperative absolute monocyte count (Pre-AMC) is reported to be a predictor of survival, but the clinical application of postoperative absolute monocyte count change (AMCc) remains unknown. The present study was designed to investigate the prognostic value of AMCc in...

journal_title：BioMed research international

authors： Song Q,Wu JZ,Wang S

更新日期：2019-08-14 00:00:00

abstract：:Tripartite Motif Containing 11 (TRIM11), an E3 ubiquitin ligase, is identified as a carcinogen causing certain human cancers. However, the specific role of TRIM11 is still uncovered in human osteosarcoma (OS) cells. To explore the role of TRIM11 in OS cells, TRIM11 was induced by silencing and overexpression in OS cel...

journal_title：BioMed research international

authors： Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

更新日期：2019-12-25 00:00:00

abstract：:Background. Advancing age, chronic inflammation, oxidative damage, and disorders of lipid metabolism are positively linked to the late-life cognitive impairment. Serum biomarkers may be associated with the cognitive status in older men. Methods. 440 old male subjects with different cognitive functions were recruited t...

journal_title：BioMed research international

authors： Ma C,Li J,Bao Z,Ruan Q,Yu Z

更新日期：2015-01-01 00:00:00

abstract：:Technological processes in the dairy industry and the further passage through the gastrointestinal tract could impair viability and functionality of probiotic bifidobacteria. In the present work, the growth in milk of nine bifidobacterial strains shared by mother and child, their survival to freeze-drying and cold sto...

journal_title：BioMed research international

authors： Peirotén A,Gaya P,Arqués JL,Medina M,Rodríguez E

更新日期：2019-01-17 00:00:00

abstract：BACKGROUND:Although expression of miR-200s is aberrant in liver fibrosis, its role in liver fibrogenesis still remains unknown. Here, we investigated the role of miR-200c in the activation of human hepatic stellate cells (HSCs) and induction of liver fibrosis. METHODS:We engineered human HSCs (LX2 cell line) to stably...

journal_title：BioMed research international

authors： Ma T,Cai X,Wang Z,Huang L,Wang C,Jiang S,Hua Y,Liu Q

更新日期：2017-01-01 00:00:00

abstract：:Bone integrity abnormality and imbalance between bone formation by osteoblasts and bone resorption by osteoclasts are known to result in metabolic bone diseases such as osteoporosis. Silymarin-rich milk thistle extract (MTE) and its component silibinin enhanced alkaline phosphatase activity of osteoblasts but reduced ...

journal_title：BioMed research international

authors： Kim JL,Kim YH,Kang MK,Gong JH,Han SJ,Kang YH

更新日期：2013-01-01 00:00:00

abstract：:Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the ef...

journal_title：BioMed research international

authors： Nicosia A,Salamone M,Mazzola S,Cuttitta A

更新日期：2015-01-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring significant high mortality and morbidity. The use of saliva, as a noninvasive tool for the diagnosis of cancer, has recently increased. Salivary mic...

journal_title：BioMed research international

authors： Salazar-Ruales C,Arguello JV,López-Cortés A,Cabrera-Andrade A,García-Cárdenas JM,Guevara-Ramírez P,Peralta P,Leone PE,Paz-Y-Miño C

更新日期：2018-11-21 00:00:00

abstract：:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h...

journal_title：BioMed research international

authors： Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MR

更新日期：2014-01-01 00:00:00

abstract：:Music exposure is known to play a positive role in learning and memory and can be a complementary treatment for anxiety and fear. However, whether juvenile music exposure affects adult behavior is not known. Two-week-old Sprague-Dawley rats were exposed to music for 2 hours daily or to background noise (controls) for ...

journal_title：BioMed research international

authors： Chen S,Liang T,Zhou FH,Cao Y,Wang C,Wang FY,Li F,Zhou XF,Zhang JY,Li CQ

更新日期：2019-07-14 00:00:00

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：:Transient receptor potential polycystic 2 (TRPP2) exerts vital roles in various types of cancer; however, its underlying mechanisms remain largely unknown. This study is aimed at investigating whether knockdown of TRPP2 affected the AMP-activated protein kinase (AMPK)/acetyl-CoA carboxylase (ACC) signaling pathway and...

journal_title：BioMed research international

authors： Li K,Chen L,Lin Z,Zhu J,Fang Y,Du J,Shen B,Wu K,Liu Y

更新日期：2020-11-14 00:00:00

abstract：:Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain. It has not been fully examined yet how nerve conduction inhibitions by l...

journal_title：BioMed research international

authors： Uemura Y,Fujita T,Ohtsubo S,Hirakawa N,Sakaguchi Y,Kumamoto E

更新日期：2014-01-01 00:00:00

abstract：:Introduction. Pelvic organ prolapse (POP) and urinary incontinence (UI) have increasing prevalence in the elderly population. The aim of this study was to compare the comorbidities of these procedures between <70 y/o and ≥70 y/o patients. Materials and Methods. In our retrospective study over a period of 2.5 years, 40...

journal_title：BioMed research international

authors： Joukhadar R,Wöckel A,Herr D,Paulus V,Radosa J,Hamza A,Solomayer E,Baum S

更新日期：2016-01-01 00:00:00

abstract：:Uraemia and long-term peritoneal dialysis (PD) can lead to fibrotic thickening of the peritoneal membrane, which may limit its dialytic function. Peritoneal fibrosis is associated with the appearance of myofibroblasts and expansion of extracellular matrix. The extent of contribution of resident peritoneal fibroblasts ...

journal_title：BioMed research international

authors： Witowski J,Kawka E,Rudolf A,Jörres A

更新日期：2015-01-01 00:00:00

abstract：:Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in periodontitis. In this study, we aimed to investigate the anti-inflammatory effects of quercetin on Porphyromonas gingivalis (P. gingivalis) ...

journal_title：BioMed research international

authors： Xiong G,Ji W,Wang F,Zhang F,Xue P,Cheng M,Sun Y,Wang X,Zhang T

更新日期：2019-08-20 00:00:00

abstract：:L5 spinal nerve ligation (SNL) in rats is one of the most popular models for studying neuropathic pain because of its high reproducibility. During the surgery, a part of the L5 paraspinal muscle is usually removed, which produces extra trauma and may potentially affect the physiological processes involved in neuropath...

journal_title：BioMed research international

authors： Huang YG,Zhang Q,Wu H,Zhang CQ

更新日期：2016-01-01 00:00:00

abstract：Background:DNA methylation is essential for regulating gene expression, and the changes of DNA methylation status are commonly discovered in disease. Therefore, identification of differentially methylation patterns, especially differentially methylated regions (DMRs), in two different groups is important for understand...

journal_title：BioMed research international

authors： Zhang Y,Wang S,Wang X

更新日期：2018-11-18 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：:This paper presents a rapid label-free method for the identification of morphological characteristics of biological cells. Based on quantitative phase microscopy as well as the connotation of phase value, the gradient operator of phase and the associated analytic processing are employed to determine the edge of differ...

journal_title：BioMed research international

authors： Tang WB,Ji Y,Zhang MM,Chen ZY,Xu YY,Wang YW

更新日期：2018-04-11 00:00:00

abstract：Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

journal_title：BioMed research international

authors： Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

更新日期：2020-09-23 00:00:00

abstract：:Objective. To confirm that physical activity program improves the symptoms of dementia and the most effective physical activity was selected to help establish exercise programs. Methods. Three databases, PubMed, Science Direct, and Willey online, were used to collect articles. The databases were published between Janu...

journal_title：BioMed research international

authors： Lee HS,Park SW,Park YJ

更新日期：2016-01-01 00:00:00

abstract：Background:Left ventricular (LV) systolic dysfunction is common in septic shock. Global longitudinal strain (GLS) measured by speckle tracking echocardiography (STE) is a useful marker of intrinsic left ventricular systolic function. However, the association between left ventricular GLS and outcome in septic patients i...

journal_title：BioMed research international

authors： Hai PD,Binh NT,Hien NVQ,Hoang NH,Hoan VN,Son PN,Hoa LTV

更新日期：2020-10-21 00:00:00

abstract：:Neurotrophic keratitis (NK) is a rare degenerative disease of the cornea caused by an impairment of corneal sensory innervation, characterized by decreased or absent corneal sensitivity resulting in epithelial keratopathy, ulceration, and perforation. The aetiopathogenesis of corneal sensory innervation impairment in ...

journal_title：BioMed research international

authors： Mantelli F,Nardella C,Tiberi E,Sacchetti M,Bruscolini A,Lambiase A

更新日期：2015-01-01 00:00:00

abstract：:Ayurvedic and traditional medical practitioners of Sri Lanka use the decoction of the immature inflorescence of Cocos nucifera L. (IC) variety aurantiaca for the treatment of menorrhagia. The progestogenic effect of the ethyl acetate soluble proanthocyanidins (EASPA) of the IC in female rats at a dose of 3.5 mg/kg bod...

journal_title：BioMed research international

authors： Ekanayake CP,Thammitiyagodage MG,Padumadasa S,Seneviratne B,Padumadasa C,Abeysekera AM

更新日期：2019-12-03 00:00:00

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00