Abstract:
Objective:To investigate the effects of arteriovenous thrombolysis combined with mechanical thrombectomy on clinical efficacy, neurological function, and the changes of nerve injury markers of acute cerebral infarct (ACI) patients. Methods:A total of 143 cases with ACI admitted to our hospital from June 2017 to June 2019 were elected as research subjects. Among them, 69 cases of patients who received treatment of arteriovenous thrombolysis were considered as group A, and 74 cases of patients who received treatment of arteriovenous thrombolysis combined with mechanical thrombectomy were considered as group B. NIHSS score, clinical efficacy, vascular recanalization, adverse reactions, hemodynamics, neurological injury indexes, duration of coma, length of hospital stay, and prognosis of patients in the two groups were compared. Results:After treatment, the NIHSS score of group A was higher than that of group B (P < 0.05), the clinical efficacy of group B was better than that of group A, and the incidence of adverse reactions was lower than that of group A (P < 0.05). There was no difference in vascular recanalization rate, duration of coma, and prognosis between the two groups (P > 0.05). Length of hospital stay, maximum peak velocity after treatment (Vs), and mean flow rate (Vm) of group A were lower than those of group B, while vascular resistance index (RI), pulsatility index (PI), serum glutamic acid (Glu), neuron-specific enolase (NES), and S100β protein detected by enzyme-linked immunosorbent assay (ELISA) of group A were higher than those of group B (P < 0.05). Conclusion:Arteriovenous thrombolysis combined with mechanical thrombectomy has a significant effect on ACI, with high safety and quick effect. In addition, it has a stronger effect on improving and protecting the neurological function of patients, which is worth promoting in clinical practice.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Ding T,Tang L,Hu B,Yuan J,Li X,Wen Jdoi
10.1155/2020/9743075subject
Has Abstractpub_date
2020-10-09 00:00:00pages
9743075eissn
2314-6133issn
2314-6141journal_volume
2020pub_type
杂志文章abstract::In esophageal squamous cell carcinoma, an elevated preoperative absolute monocyte count (Pre-AMC) is reported to be a predictor of survival, but the clinical application of postoperative absolute monocyte count change (AMCc) remains unknown. The present study was designed to investigate the prognostic value of AMCc in...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2702719
更新日期:2019-08-14 00:00:00
abstract:Objective of Study:To investigate, using the FEM, the influence of different notching angles on a zirconium dioxide coping with the aim of establishing the optimal connection conditions with veneering ceramic. Materials and Methods:To calculate the stresses in the connection between zirconia coping and veneering ceram...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/7485409
更新日期:2019-07-01 00:00:00
abstract::Iran is one of the six countries with the most cutaneous leishmaniasis (CL) patients. Understanding better the genotypes of the parasite population in relation to geography and climate is critical to achieving better CL control. We aimed to characterise the population structure of Leishmania tropica, the cause of anth...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6049198
更新日期:2018-06-06 00:00:00
abstract::Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/4192745
更新日期:2020-02-01 00:00:00
abstract::Embryology of normal web space creation and the genetics of syndactyly in humans and experimental animals are well described in the literature. In this review, the author offers a 3-step pathway of pathogenesis for syndactyly. The first step is initiated either by the overactivation of the WNT canonical pathway or the...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/9652649
更新日期:2019-09-15 00:00:00
abstract::Human dental pulp stem cells (DPSCs) hold great promise in bone regeneration. However, the exact mechanism of osteogenic differentiation of DPSCs remains unknown, especially the role of exosomes played in. The DPSCs were cultured and received osteogenic induction; then, exosomes from osteogenic-induced DPSCs (OI-DPSC-...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6319395
更新日期:2020-09-28 00:00:00
abstract:Objectives:The study aimed to compare the accuracy of different methods of data acquisition and data reconstruction and to assess their usefulness for 3D printing of tooth replicas. Methods:3-dimensional models of molar and canine teeth obtain utilizing CBCT examination with different protocols, and optical scanning w...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/4985121
更新日期:2019-04-10 00:00:00
abstract:OBJECTIVE:Abnormal expression of ABCA1 and ABCG1 in the placenta can elicit lipid metabolism disorder and adverse pregnancy outcomes. However, whether it is associated with preterm delivery remains unclear. Our present study aimed to evaluate the relationship between abnormal expression of ABCA1 or ABCG1 and preterm de...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2017/8248094
更新日期:2017-01-01 00:00:00
abstract::D-Ribose is a five-carbon sugar and generally used as an energy source to improve athletic performance and the ability. The culture conditions for maximum D-ribose production performance from cheap raw material corn starch hydrolysate were improved by using one-factor-at-a-time experiments and a three-level Box-Behnke...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/535097
更新日期:2015-01-01 00:00:00
abstract::This study documented the population dynamics of Biomphalaria and associated natural infections with digenetic trematodes, along the shores of Lake Albert and Lake Victoria, recording local physicochemical factors. Over a two-and-a-half-year study period with monthly sampling, physicochemical factors were measured at ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/717261
更新日期:2015-01-01 00:00:00
abstract::Although disorders of the stomatognathic system are common, the mechanisms involved are unknown. Our objective was to study the changes in the masseter muscles after unilateral exodontia. Molar extraction was performed on Wistar rats (left side), and the animals were sacrificed after either 14 or 26 days. The masseter...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/563463
更新日期:2014-01-01 00:00:00
abstract::Oyster mushroom Pleurotus florida was cultivated on different combinations of wheat straw (WS) as basal substrate and oyster shell powder (OSP) supplement. The OSP supplementation considerably responded to different cultivation phases. The mycelium grew fast and showed rapid growth rate (8.91 mmd(-1)) in WS + OSP (97 ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/386265
更新日期:2014-01-01 00:00:00
abstract::The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2015/878517
更新日期:2015-01-01 00:00:00
abstract::There is an emerging body of evidence that chemoresistance and minimal residual disease result from selective resistance of a cell subpopulation from the original tumor that is molecularly and phenotypically distinct. These cells are called "cancer stem cells" (CSCs). In this review, we analyze the potential targeting...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/859871
更新日期:2014-01-01 00:00:00
abstract::Osteoarthritis (OA) is one of the most common debilitating disorders among the elderly population. At present, there is no definite cure for the underlying causes of OA. However, adipose tissue-derived stem cells (ADSCs) in the form of stromal vascular fraction (SVF) may offer an alternative at this time. ADSCs are on...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/4702674
更新日期:2016-01-01 00:00:00
abstract::5-Florouracil (5-FU) is the basic agent used in the treatment of gastric cancer. Capecitabine, a prodrug of 5-FU, displays increased antitumor efficacy compared with 5-FU in the clinic. 5'-Deoxy-5-fluorouracil (5'-DFUR), the metabolite of capecitabine, is converted to 5-FU by the enzyme thymidine phosphorylase (TP), w...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/132793
更新日期:2013-01-01 00:00:00
abstract:Purpose:We evaluated the efficacies of the adaptive steepest descent projection onto convex sets (ASD-POCS), simultaneous algebraic reconstruction technique (SART), filtered back projection (FBP), and maximum likelihood expectation maximization (MLEM) total variation minimization iterative algorithms for reducing expos...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/5239082
更新日期:2018-06-19 00:00:00
abstract::Spinocerebellar ataxia-3 (SCA3) is the most common dominant inherited ataxia worldwide and is caused by an unstable CAG trinucleotide expansion mutation within the ATXN3 gene, resulting in an expanded polyglutamine tract within the ATXN3 protein. Many in vitro studies have examined the role of autophagy in neurodegene...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/6701793
更新日期:2016-01-01 00:00:00
abstract::Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in periodontitis. In this study, we aimed to investigate the anti-inflammatory effects of quercetin on Porphyromonas gingivalis (P. gingivalis) ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6282635
更新日期:2019-08-20 00:00:00
abstract::In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of in vivo and in vitro studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/1893474
更新日期:2016-01-01 00:00:00
abstract:CONTEXT:IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. PATIENTS AND METHODS:We studied 64 ad...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2014/936031
更新日期:2014-01-01 00:00:00
abstract::Human adipose-derived stem cells (hASCs) are an attractive cell source for therapeutic applicability in diverse fields for the repair and regeneration of damaged or malfunctioning tissues and organs. There is a growing number of cell therapies using stem cells due to their characteristics of modulation of immune syste...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/143504
更新日期:2015-01-01 00:00:00
abstract::A dentin-cement-prosthesis complex restored with either all-porcelain, cured resin-composite, or cast base metal alloy and cemented with either of the different resin cements was trimmed into a mini-dumbbell shape for tensile testing. The fractured surfaces and characterization of the dentin-cement interface of bonded...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/656948
更新日期:2015-01-01 00:00:00
abstract::It has been indicated that activation of peripheral imidazoline I2-receptor (I-2R) may reduce the blood pressure in spontaneously hypertensive rats (SHRs). Also, guanidinium derivatives show the ability to activate imidazoline receptors. Thus, it is of special interest to characterize the I-2R using guanidinium deriva...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/182846
更新日期:2014-01-01 00:00:00
abstract::The proper methylation status of histones is essential for appropriate cell lineage and organogenesis. EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. The pig is an increasing important animal model for molecular study and pharmaceutical research. Ho...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5315930
更新日期:2020-10-05 00:00:00
abstract:Purpose:To evaluate the effects of intravitreal ranibizumab (IVR) treatment on the blood flow of the optic nerve head (ONH) and of retinal vessels of the peripapillary region of eyes with diabetic macular edema (DME) assessed using laser speckle flowgraphy (LSFG). Methods:Forty eyes of 30 patients treated with IVR for...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/9496242
更新日期:2020-02-10 00:00:00
abstract::Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]IPQA derivative as ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/549359
更新日期:2013-01-01 00:00:00
abstract:Background:The incidence of osteoporotic fractures is increasing. In this study, we explored the activities of Wnt/β-catenin signaling in bone tissues with iron accumulation. Methods:We established rat bipedal walking models (RBWM), and a portion of our RBWM rats were intraperitoneally injected with ferric ammonium ci...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8256261
更新日期:2020-05-24 00:00:00
abstract:PURPOSE:Suppressor of cytokine signaling 7 (SOCS7) is a member of the SOCS family and is known to interact with phospholipase Cγ-1 (PLCγ-1), a key downstream mediator of the hepatocyte growth factor (HGF)/C-MET axis. Here, we report our observations of the effect of knocking down SOCS7 gene on the behaviour of breast c...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/648040
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:The aim of our work was to investigate the causal connection between M1 and M2 macrophage phenotypes occurrence and prostate cancer, their correlation with tumor extension (ECE), and biochemical recurrence (BR). PATIENT AND METHODS:Clinical and pathological data were prospectively gathered from 93 patient...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/486798
更新日期:2014-01-01 00:00:00