Elevated red blood cell distribution width as a simple prognostic factor in patients with symptomatic multiple myeloma.

abstract：:Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer with the highest incidence worldwide. HNSCC is often diagnosed at advanced stages, incurring significant high mortality and morbidity. The use of saliva, as a noninvasive tool for the diagnosis of cancer, has recently increased. Salivary mic...

journal_title：BioMed research international

authors： Salazar-Ruales C,Arguello JV,López-Cortés A,Cabrera-Andrade A,García-Cárdenas JM,Guevara-Ramírez P,Peralta P,Leone PE,Paz-Y-Miño C

更新日期：2018-11-21 00:00:00

abstract：:One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...

journal_title：BioMed research international

authors： Holczer M,Márton M,Kurucz A,Bánhegyi G,Kapuy O

更新日期：2015-01-01 00:00:00

abstract：:Despite good safety records, vaccines given to young children can cause adverse events. We investigated the reported adverse events following immunization (AEFI) of vaccines given to children of less than seven years of age during the first ten years (1998 to 2008) in the state of Rondonia, Brazil. We worked with the ...

journal_title：BioMed research international

authors： Cunha MP,Dórea JG,Marques RC,Leão RS

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of two foot placements (normal or posterior placement) and three arm positions (hands on the thighs, arms crossed over chest, and augmented arm position with elbow extended) on the five times sit-to-stand (FTSTS) test times of individuals with chronic stroke. DESIGN:Cross-sectional...

journal_title：BioMed research international

authors： Kwong PW,Ng SS,Chung RC,Ng GY

更新日期：2014-01-01 00:00:00

abstract：:Spasticity is the velocity-dependent increase in muscle tone due to the exaggeration of stretch reflex. It is only one of the several components of the upper motor neuron syndrome (UMNS). The central lesion causing the UMNS disrupts the balance of supraspinal inhibitory and excitatory inputs directed to the spinal cor...

journal_title：BioMed research international

authors： Trompetto C,Marinelli L,Mori L,Pelosin E,Currà A,Molfetta L,Abbruzzese G

更新日期：2014-01-01 00:00:00

abstract：:Heteronemin is a bioactive marine sesterterpene isolated from the sponge Hyrtios sp. Previous reports have shown that heteronemin possesses anticancer activity. Here, heteronemin displayed cytotoxic effects against three human cancer cell lines (A549, ACHN, and A498) and exhibited potent activity in A498 human renal c...

journal_title：BioMed research international

authors： Wu SY,Sung PJ,Chang YL,Pan SL,Teng CM

更新日期：2015-01-01 00:00:00

abstract：:Metabolic bone disorder is usually caused by abnormalities of minerals and hormones metabolism. Recently, it has been proved by several studies that the renin-angiotensin system (RAS) in local bone tissue is directly involved in bone metabolism. Activation of skeletal RAS plays an important role in bone metabolic diso...

journal_title：BioMed research international

authors： Gebru Y,Diao TY,Pan H,Mukwaya E,Zhang Y

更新日期：2013-01-01 00:00:00

abstract：:Purpose. Kawasaki disease (KD) is a systemic vasculitis and is a leading cause of coronary artery lesions (CALs) in childhood. Our previous study has shown higher levels of serum Resistin in KD patients with coronary aneurysm. This study aimed at examining the association of Resistin with inflammatory cytokine express...

journal_title：BioMed research international

authors： Gao F,Si F,Feng S,Yi Q,Liu R

更新日期：2016-01-01 00:00:00

abstract：Background:Urogenital schistosomiasis remains a public health problem in Tanzania. Control programs mostly target school-going children ignoring other vulnerable groups like women of child bearing age. Previous evidence has shown that women of reproductive age suffer greatest morbidities in endemic areas. This study so...

journal_title：BioMed research international

authors： Rite EE,Kapalata SN,Munisi DZ

更新日期：2020-10-23 00:00:00

abstract：Objective:To observe the effect of adenosine A1 receptor in the hippocampus of mice on GSK-3β phosphorylation level and elucidate the underlying mechanisms of electroacupuncture pretreatment by activating Α1 receptor mediating cerebral ischemia-reperfusion injury. Method:The model of middle cerebral artery occlusion (...

journal_title：BioMed research international

authors： Geng W,Cai L,Han K,Li D,Mo Y,Dai Q,Tang H,Zhang M,Akuetteh PDP,Balelang MF,Wang J

更新日期：2020-02-20 00:00:00

abstract：BACKGROUND:Maternal thyroid dysfunction in early pregnancy may increase the risk of adverse pregnancy complications and neurocognitive deficiencies in the developing fetus. Currently, some researchers demonstrated that body mass index (BMI) is associated with thyroid function in nonpregnant population. Hence, the Ameri...

journal_title：BioMed research international

authors： Han C,Li C,Mao J,Wang W,Xie X,Zhou W,Li C,Xu B,Bi L,Meng T,Du J,Zhang S,Gao Z,Zhang X,Yang L,Fan C,Teng W,Shan Z

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study was to examine whether dexmedetomidine improves acute liver injury in a rat model. Twenty-eight male Wistar albino rats weighing 300-350 g were allocated randomly to four groups. In group 1, normal saline (NS) was injected into the lungs and rats were allowed to breathe spontaneously. In group 2,...

journal_title：BioMed research international

authors： Sen V,Güzel A,Şen HS,Ece A,Uluca U,Söker S,Doğan E,Kaplan İ,Deveci E

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus is a major health problem that affects a patient's life quality throughout the world due to its worst complications. It was recognized that chronic hyperglycemia with oxidative stress was the major cause of male infertility. Echinacea purpurea ethanol extract (EE) contains phenolic acid and isobutyla...

journal_title：BioMed research international

authors： Mao CF,Zhang XR,Johnson A,He JL,Kong ZL

更新日期：2018-08-30 00:00:00

abstract：:Numerous studies have shown that long noncoding RNAs (lncRNAs) play essential roles in the development and progression of human cardiovascular diseases. However, whether lncRNA ezrin antisense RNA 1 (EZR-AS1) is associated with the progression of coronary heart disease (CHD) remains unclear. Accordingly, the aim of th...

journal_title：BioMed research international

authors： You G,Long X,Song F,Huang J,Tian M,Xiao Y,Deng S,Wu Q

更新日期：2020-05-22 00:00:00

abstract：:The aim of this study was to find out the ideal cut-off level of phosphate for safe healing when deformity correction and concomitant lengthening are indicated in the two different skeletal maturity groups of patients with rickets. Thirty-nine hypophosphatemic rickets patients were selected for the study and were divi...

journal_title：BioMed research international

authors： Song SH,Lee H,Jeong JM,Cho WI,Kim SE,Song HR

更新日期：2014-01-01 00:00:00

abstract：:The distribution of the induced electric field (E-field) during transcranial magnetic stimulation (TMS) depends on the individual anatomical structure of the brain as well as coil positioning. Inappropriate stimulation may degrade the efficacy of TMS or even induce adverse effects. Therefore, optimizing the E-field ac...

journal_title：BioMed research international

authors： Li C,Liu C,Yang L,He L,Wu T

更新日期：2019-11-03 00:00:00

abstract：:Diabetes mellitus is a disease which has affected 415 million patients in 2015. In an effort to replace the significant demands on transplantation and morbidity associated with transplantation, the production of β-like cells differentiated from induced pluripotent stem cells (iPSCs) was evaluated. This approach is ass...

journal_title：BioMed research international

authors： Wan J,Huang Y,Zhou P,Guo Y,Wu C,Zhu S,Wang Y,Wang L,Lu Y,Wang Z

更新日期：2017-01-01 00:00:00

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00

abstract：:Fluconazole is a broad-spectrum triazole antifungal that is well-established as the first-line treatment for Candida albicans infections. Despite its extensive use, reports on its genotoxic/mutagenic effects are controversial; therefore, further studies are needed to better clarify such effects. African green monkey k...

journal_title：BioMed research international

authors： Correa RMDS,Mota TC,Guimarães AC,Bonfim LT,Burbano RR,Bahia MO

更新日期：2018-11-01 00:00:00

abstract：:The simultaneous effect of flexible wall and multiple stenoses on the flow and mass transfer of blood is investigated through numerical computation and simulations. The solution is obtained using the Marker and Cell technique on an axisymmetric model of Newtonian blood flow. The results compare favorably with physical...

journal_title：BioMed research international

authors： Alsemiry RD,Sarifuddin,Mandal PK,Sayed HM,Amin N

更新日期：2020-01-31 00:00:00

abstract：Background:The kaya business is known to pose significant health-related risks to female migrants. This study sought to explore the health-related concerns of female head porters in the Mallam Atta market, Accra, Ghana. Methods:A qualitative study was conducted in which twenty female head porters at the Mallam Atta ma...

journal_title：BioMed research international

authors： Nyarko SH,Tahiru AM

更新日期：2018-02-13 00:00:00

abstract：:Natural matrices are important sources of new antitumor and antimicrobial compounds. Species such as Laurus nobilis L. (laurel) might be used for this purpose, considering its medicinal properties. Herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts...

journal_title：BioMed research international

authors： Dias MI,Barreira JC,Calhelha RC,Queiroz MJ,Oliveira MB,Soković M,Ferreira IC

更新日期：2014-01-01 00:00:00

abstract：:Although cases of Mediterranean spotted fever (MSF) have been reported for decades in southeastern Romania, there are few published data. We retrospectively studied 339 patients, diagnosed with MSF at the National Institute of Infectious Diseases "Prof. Dr. Matei Bals" between 2000 and 2011, in order to raise awarenes...

journal_title：BioMed research international

authors： Pitigoi D,Olaru ID,Badescu D,Rafila A,Arama V,Hristea A

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study was to investigate the impact of polishing methods on the bonding effectiveness and durability of different resin cements to dentin. The dentin surfaces were either treated with a fine-grit diamond bur (polishing A) or further polished by polishing disks (polishing B), and then they were bond...

journal_title：BioMed research international

authors： Ren L,Li M,Pan Y,Meng X

更新日期：2018-02-28 00:00:00

abstract：:The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...

journal_title：BioMed research international

authors： Agarwal SK,Foster WG

更新日期：2015-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the second leading cause of cancer deaths in Taiwan. CD44, one of the well-known tumor markers, plays an essential role in tumor cell differentiation, invasion, and metastasis. We investigated the CD44 single-nucleotide polymorphisms (SNPs) with environmental risk factors related to H...

journal_title：BioMed research international

authors： Chou YE,Hsieh MJ,Chiou HL,Lee HL,Yang SF,Chen TY

更新日期：2014-01-01 00:00:00

abstract：Background:Osteonecrosis of the femoral head (ONFH) is a challenge for surgeons and is still without effective treatment method. This study is aimed at evaluating the combined pharmacotherapy with alendronate and desferoxamine for preventing glucocorticoid-induced osteonecrosis of the femoral head (GIOFH) and evaluatin...

journal_title：BioMed research international

authors： Sheng H,Lao Y,Zhang S,Ding W,Lu D,Xu B

更新日期：2020-09-21 00:00:00

abstract：:Synovitis plays an important role in the pathogenesis of arthritis, which is closely related to the joint swell and pain of patients. The purpose of this study was to investigate the anti-inflammatory effects of pulsed electromagnetic fields (PEMF) on synovitis and its underlying mechanisms. Destabilization of the med...

journal_title：BioMed research international

authors： Ouyang J,Zhang B,Kuang L,Yang P,Du X,Qi H,Su N,Jin M,Yang J,Xie Y,Tan Q,Chen H,Chen S,Jiang W,Liu M,Luo X,He M,Ni Z,Chen L

更新日期：2020-05-26 00:00:00

abstract：OBJECTIVE:Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and...

journal_title：BioMed research international

authors： Suwa M,Yamaguchi S,Komori T,Kajimoto S,Kino M

更新日期：2015-01-01 00:00:00

abstract：:Emergence and spread of pandemic strains of Vibrio parahaemolyticus have drawn attention to make detailed study on their genomes. The pathogenicity of V. parahaemolyticus has been associated with thermostable-direct hemolysin (TDH) and/or TDH-related hemolysin (TRH). The present study evaluated characteristics of tdh ...

journal_title：BioMed research international

authors： Bhowmik SK,Pazhani GP,Ramamurthy T

更新日期：2014-01-01 00:00:00