Somatostatin receptor based imaging and radionuclide therapy.

abstract：Background:Acute myocardial infarction (AMI) is regarded as an urgent clinical entity, and identification of differentially expressed genes, lncRNAs, and altered pathways shall provide new insight into the molecular mechanisms behind AMI. Materials and Methods:Microarray data was collected to identify key genes and ln...

journal_title：BioMed research international

authors： Sheng X,Fan T,Jin X

更新日期：2020-10-06 00:00:00

abstract：:Presynaptic and postsynaptic neurotoxins are proteins which act at the presynaptic and postsynaptic membrane. Correctly predicting presynaptic and postsynaptic neurotoxins will provide important clues for drug-target discovery and drug design. In this study, we developed a theoretical method to discriminate presynapti...

journal_title：BioMed research international

authors： Tang H,Yang Y,Zhang C,Chen R,Huang P,Duan C,Zou P

更新日期：2017-01-01 00:00:00

abstract：Background:Cardiogenic shock is associated with high mortality, despite new strategies for reperfusion therapy. Short-term circulatory support devices may provide adequate support for appropriate myocardial and organ perfusion. Objectives:This review is aimed at evaluating the impact on survival when using venoarteria...

journal_title：BioMed research international

authors： Zavalichi MA,Nistor I,Nedelcu AE,Zavalichi SD,Georgescu CMA,Stătescu C,Covic A

更新日期：2020-04-19 00:00:00

abstract：:D-Ribose is a five-carbon sugar and generally used as an energy source to improve athletic performance and the ability. The culture conditions for maximum D-ribose production performance from cheap raw material corn starch hydrolysate were improved by using one-factor-at-a-time experiments and a three-level Box-Behnke...

journal_title：BioMed research international

authors： Wei Z,Zhou J,Sun W,Cui F,Xu Q,Liu C

更新日期：2015-01-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial ...

journal_title：BioMed research international

authors： Osayi SN,Bloomston M,Schmidt CM,Ellison EC,Muscarella P

更新日期：2014-01-01 00:00:00

abstract：:Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets play an integral role in intercellular communication, mediating inflammatory and immunomodulatory activities. Our knowledge about how platelets modulate inflammatory and immunity has greatly improved in recent years. In this revi...

journal_title：BioMed research international

authors： Yun SH,Sim EH,Goh RY,Park JI,Han JY

更新日期：2016-01-01 00:00:00

abstract：:Immunodeficiency is associated with higher cancer incidence. However, it is unknown whether there is a link between immunodeficiency and development of multiple primary malignancies. In the present study we analyse this link focusing on kidney-transplanted patients, as they are at higher risk of developing cancer due ...

journal_title：BioMed research international

authors： Santangelo ML,Criscitiello C,Renda A,Federico S,Curigliano G,Dodaro C,Scotti A,Tammaro V,Calogero A,Riccio E,Pisani A,Carlomagno N

更新日期：2015-01-01 00:00:00

abstract：Introduction:The sources of Reactive Oxidative Species (ROS) in the organism are the respiratory processes occurring in cells catalyzed by different enzymes. Operation of ROS is balanced by antioxidants, the compounds; although present in low concentrations, they significantly inhibit the degree of oxidation of particu...

journal_title：BioMed research international

authors： Kuciel-Lewandowska J,Gnus J,Pawlik-Sobecka L,Płaczkowska S,Kokot I,Kasperczak M,Paprocka-Borowicz M

更新日期：2018-01-02 00:00:00

abstract：BACKGROUND:This study investigated whether the 1 : 2 ω-3/ω-6 ratio may reduce proinflammatory response in human alveolar cells (A549) exposed to an ex vivo inflammatory stimulus (bronchoalveolar lavage fluid (BALF) of acute respiratory distress syndrome (ARDS) patients). Methods. We exposed A549 cells to the BALF colle...

journal_title：BioMed research international

authors： Cotogni P,Trombetta A,Muzio G,Maggiora M,Canuto RA

更新日期：2015-01-01 00:00:00

abstract：:Bitterness is an important taste sensation for chickens, which provides useful sensory information for acquisition and selection of diet, and warns them against ingestion of potentially harmful and noxious substances in nature. Bitter taste receptors (T2Rs) mediate the recognition of bitter compounds belonging to a fa...

journal_title：BioMed research international

authors： Su Y,Jie H,Zhu Q,Zhao X,Wang Y,Yin H,Kumar Mishra S,Li D

更新日期：2019-10-31 00:00:00

abstract：:There is mounting evidence that burnout is a risk factor for cardiovascular disease (CVD). Stress-related dysregulation of the sympathetic and parasympathetic system and the hypothalamic pituitary adrenal (HPA) axis may explain the enhanced risk for CVD. To test this hypothesis, 55 patients (34 males and 21 females) w...

journal_title：BioMed research international

authors： de Vente W,van Amsterdam JG,Olff M,Kamphuis JH,Emmelkamp PM

更新日期：2015-01-01 00:00:00

abstract：Background:Previous studies have investigated the association between the use of bisphosphonates and the development of breast cancer, which presented controversial results. Thus, this meta-analysis was conducted to summarize the current evidence of the association of bisphosphonate use with breast cancer risk. Method...

journal_title：BioMed research international

authors： Peng R,Liang X,Zhang G,Yao Y,Chen Z,Pan X,Wang J,Liu G

更新日期：2020-10-06 00:00:00

abstract：:Lower back pain is the leading cause of disability worldwide. Discogenic pain secondary to intervertebral disc degeneration is a significant cause of low back pain. Disc degeneration is a complex multifactorial process. Animal models are essential to furthering understanding of the degenerative process and testing pot...

journal_title：BioMed research international

authors： Daly C,Ghosh P,Jenkin G,Oehme D,Goldschlager T

更新日期：2016-01-01 00:00:00

abstract：:Toll-like receptors (TLRs), a critical family of pattern recognition receptors (PRRs), are responsible for the innate immune responses via signalling pathways to provide effective host defence against pathogen infections. However, TLR-signalling pathways are also likely to stringently regulate tissue maintenance and h...

journal_title：BioMed research international

authors： He X,Jing Z,Cheng G

更新日期：2014-01-01 00:00:00

abstract：:Endothelial barrier dysfunction, which is a serious problem that occurs in various inflammatory conditions, permits extravasation of serum components into the surrounding tissues, leading to edema formation and organ failure. Pigment epithelium-derived factor (PEDF), which is a major endogenous antagonist, has been im...

journal_title：BioMed research international

authors： He T,Zhao L,Zhang D,Zhang Q,Jia J,Hu J,Huang Y

更新日期：2015-01-01 00:00:00

abstract：:POZ/BTB domains are widespread modules detected in a variety of different biological contexts. Here, we report a biophysical characterization of the POZ/BTB of KCTD6, a protein that is involved in the turnover of the muscle small ankyrin-1 isoform 5 and, in combination with KCTD11, in the ubiquitination and degradatio...

journal_title：BioMed research international

authors： Pirone L,Esposito C,Correale S,Graziano G,Di Gaetano S,Vitagliano L,Pedone E

更新日期：2013-01-01 00:00:00

abstract：Introduction:The aim of this research was to test, in an animal model, the nerve regeneration technique with a hypoallergenic acellular dermal matrix used to wrap the microsurgical neural suture. Materials and Methods:Two groups of rats received the cut of limb right median nerves. The regeneration technique considers...

journal_title：BioMed research international

authors： Colonna MR,Fazio A,Costa AL,Galletti F,Lo Giudice R,Galletti B,Galletti C,Lo Giudice G,Dell'Aversana Orabona G,Papalia I,Ronchi G,Geuna S

更新日期：2019-06-17 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are involved in the remodeling of extracellular matrix in various tissues. Their functioning could be related to the formation of complexes, containing MMP9, MMP2, tissue inhibitor of metalloproteinases type 1 (TIMP1), and neutrophil gelatinase-associated lipocalin (NGAL). Such complex...

journal_title：BioMed research international

authors： Kiczak L,Tomaszek A,Bania J,Paslawska U,Zacharski M,Noszczyk-Nowak A,Janiszewski A,Skrzypczak P,Ardehali H,Jankowska EA,Ponikowski P

更新日期：2013-01-01 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：Background:Oxidative stress is an important factor during age-related cataract formation. Apoptosis and autophagy induced by oxidative stress have been reported as key factors in age-related cataract. In our research, we investigated the role of let-7c-3p in the regulation of autophagy and apoptosis during the formatio...

journal_title：BioMed research international

authors： Li T,Huang Y,Zhou W,Yan Q

更新日期：2020-03-16 00:00:00

abstract：:A large body of evidence has emerged over the past years to show the critical role played by inflammation in the pathogenesis of several diseases including some cardiovascular, neoplastic, and neurodegenerative diseases, previously not considered inflammation-related. The anti-inflammatory action of ω-3 polyunsaturate...

journal_title：BioMed research international

authors： Calviello G,Su HM,Weylandt KH,Fasano E,Serini S,Cittadini A

更新日期：2013-01-01 00:00:00

abstract：Background:Although sleeve gastrectomy results in good weight loss and metabolic improvements, it is an irreversible procedure. Therefore, we attempted to assess the possibility of creating a sleeved stomach without resection. Material and Methods. A total of 22 male Sprague-Dawley rats with type 2 diabetes were random...

journal_title：BioMed research international

authors： Zhang W,Widjaja J,Yao L,Shao Y,Zhu X,Li C

更新日期：2020-05-01 00:00:00

abstract：:The most expedient unit of the human body is its cell. Encapsulated within the cell are many infinitesimal entities and molecules which are protected by a cell membrane. The proteins that are associated with this lipid based bilayer cell membrane are known as membrane proteins and are considered to play a significant ...

journal_title：BioMed research international

authors： Butt AH,Khan SA,Jamil H,Rasool N,Khan YD

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of this study is to describe the robotic assisted transfer device (RATD) and an initial focus group evaluation by end users. The purpose of the device is to aid in the transfers of people with disabilities to and from their electric powered wheelchair (EPW) onto other surfaces. The device can be used fo...

journal_title：BioMed research international

authors： Grindle GG,Wang H,Jeannis H,Teodorski E,Cooper RA

更新日期：2015-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder with two hallmarks: β-amyloid plagues and neurofibrillary tangles. It is one of the most alarming illnesses to elderly people. No effective drugs and therapies have been developed, while mechanism-based explorations of therapeutic approaches have bee...

journal_title：BioMed research international

authors： Jia Q,Deng Y,Qing H

更新日期：2014-01-01 00:00:00

abstract：:Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin-2 (Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of this study was to introduce a computational simulation approach to screen aptamers with high binding ability for Ang2. We carried out...

journal_title：BioMed research international

authors： Hu WP,Kumar JV,Huang CJ,Chen WY

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported in SAH, their origin remains unclear. The aim of this study was to report the detection of ES during routine TCD monitoring in patients with aneurysmal SAH. METHODS:...

journal_title：BioMed research international

authors： Paschoal FM Jr,de Almeida Lins Ronconi K,de Lima Oliveira M,Nogueira Rde C,Paschoal EH,Teixeira MJ,Figueiredo EG,Bor-Seng-Shu E

更新日期：2015-01-01 00:00:00

abstract：:Chromosome/DNA instability could be one of the primary causes of malignant cell transformation. The objective of the present study was to evaluate the spontaneous genetic damages in exfoliated cells of buccal mucosa of head and neck cancer (HNC) by counting micronucleus (MN) and binucleated (BN) cells frequencies. MN ...

journal_title：BioMed research international

authors： Khlifi R,Trabelsi-Ksibi F,Chakroun A,Rebai A,Hamza-Chaffai A

更新日期：2013-01-01 00:00:00

abstract：:Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...

journal_title：BioMed research international

authors： Wang P,Wang J,Ma J,Jin G,Guan X

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00