Development and remodeling of the vertebrate blood-gas barrier.

abstract：:Obesity or maternal overnutrition during pregnancy and lactation might have long-term consequences in offspring health. Fetal programming is characterized by adaptive responses to specific environmental conditions during early life stages. Programming alters gene expression through epigenetic modifications leading to ...

journal_title：BioMed research international

authors： Montalvo-Martínez L,Maldonado-Ruiz R,Cárdenas-Tueme M,Reséndez-Pérez D,Camacho A

更新日期：2018-06-20 00:00:00

abstract：Objective:This paper included a retrospective review of the effect of tranexamic acid (TXA) combined with pressure bandaging on hemostasis of patients who received a unilateral total knee arthroplasty (TKA) from 2017 to 2019. Methods:A total of 197 patients undergoing TKA were chosen to be classified into 2 groups, th...

journal_title：BioMed research international

authors： Li GH,Ding LM,Sun L,Wang F

更新日期：2020-11-02 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：:Although triacylglycerol, the major component for lipid storage, is essential for normal physiology, its excessive accumulation causes obesity in adipose tissue and is associated with organ dysfunction in nonadipose tissue. Here, we focused on the Drosophila model to develop therapeutics for preventing obesity. The br...

journal_title：BioMed research international

authors： Men TT,Thanh DN,Yamaguchi M,Suzuki T,Hattori G,Arii M,Huy NT,Kamei K

更新日期：2016-01-01 00:00:00

abstract：Objectives:Assessing the therapeutic efficacy of superparamagnetic iron oxide nanoparticles (SPIO) labeled bone marrow-derived mesenchymal stem cells (BM-MSCs) on experimental liver fibrosis and associated dysplasia. Materials and Methods:MSCs were obtained from 10 male Sprague-Dawley rats while 50 female rats were di...

journal_title：BioMed research international

authors： Khalifa YH,Mourad GM,Stephanos WM,Omar SA,Mehanna RA

更新日期：2019-11-06 00:00:00

abstract：:Uveitic glaucoma (UG) typically is associated with very high intraocular pressure (IOP) and more intense optic nerve damage than other glaucoma types. This secondary glaucoma requires an early diagnosis and adequate management of both uveitis and glaucoma. It is mandatory to identify the mechanisms of IOP elevation th...

journal_title：BioMed research international

authors： Muñoz-Negrete FJ,Moreno-Montañés J,Hernández-Martínez P,Rebolleda G

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the potential relationship between exosomal miRNAs and clinical symptoms in patients with multiple myeloma (MM). Forty-eight newly diagnosed myeloma patients and sixteen normal donors were enrolled in the study. The results showed that the relative expression levels of let-7c-5p, let-7d-5p, miR-14...

journal_title：BioMed research international

authors： Zhang ZY,Li YC,Geng CY,Wang HJ,Chen WM

更新日期：2019-12-14 00:00:00

abstract：PURPOSE:The primary aim of this study was to explore if classification, whether using the BI-RADS categories based on CEUS or conventional ultrasound, was conducive to the identification of benign and malignant category 3 or 4 small breast lesions. MATERIAL AND METHODS:We evaluated 30 malignant and 77 benign small bre...

journal_title：BioMed research international

authors： Zhang JX,Cai LS,Chen L,Dai JL,Song GH

更新日期：2014-01-01 00:00:00

abstract：:Ambient assisted living (AAL) aims to help older persons "age-in-place" and manage everyday activities using intelligent and pervasive computing technology. AAL research, however, has yet to explore how AAL might support or collaborate with informal care partners (ICPs), such as relatives and friends, who play importa...

journal_title：BioMed research international

authors： Hwang AS,Truong KN,Cameron JI,Lindqvist E,Nygård L,Mihailidis A

更新日期：2015-01-01 00:00:00

abstract：:Nitric oxide (NO) has a wide variety of physiological functions in the kidney. Besides the regulatory effects in intrarenal haemodynamics and glomerular microcirculation, in vivo studies reported the diuretic and natriuretic effects of NO. However, opposite results showing the stimulatory effect of NO on Na+ reabsorpt...

journal_title：BioMed research international

authors： Satoh N,Nakamura M,Suzuki A,Tsukada H,Horita S,Suzuki M,Moriya K,Seki G

更新日期：2017-01-01 00:00:00

abstract：:Objectives. The aim of the study is to detect the prevalence and the characteristics of infraorbital canal and Haller's cells on panoramic radiography of edentulous patients. Methods. The study group comprised 291 panoramic radiographs of edentulous patients. Radiographs were interpreted for the visibility and charact...

journal_title：BioMed research international

authors： Yesilova E,Bayrakdar IS

更新日期：2018-07-08 00:00:00

abstract：:The aim of the present study was to investigate the suitability of insoluble Eudragit® water dispersions (NE, NM, RL, and RS) for direct high-shear granulation of very soluble levetiracetam in order to decrease its burst effect from HPMC K100M matrices. The process characteristics, ss-NMR analysis, in vitro dissolutio...

journal_title：BioMed research international

authors： Mašková E,Naiserová M,Kubová K,Mašek J,Pavloková S,Urbanová M,Brus J,Vysloužil J,Vetchý D

更新日期：2019-03-05 00:00:00

abstract：:Spinal cord stimulation has been utilized for decades in the treatment of numerous conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer pain, and others. The placement of the stimulating electrode array was originally subdural but, to minimize surgical complexity and reduce the risk...

journal_title：BioMed research international

authors： Gibson-Corley KN,Flouty O,Oya H,Gillies GT,Howard MA

更新日期：2014-01-01 00:00:00

abstract：Background:The tumor volume of high-grade glioma (HGG) after surgery is usually determined by contrast-enhanced MRI (CE-MRI), but the clinical target volume remains controversial. Functional magnetic resonance imaging (multimodality MRI) techniques such as magnetic resonance perfusion-weighted imaging (PWI) and diffusi...

journal_title：BioMed research international

authors： Fei Q,Qian LX,Zhang YJ,Guo WJ,Bian XH,Yin L,Yan PW,Wang TT,Qian PD,Guo Z,He X

更新日期：2020-08-10 00:00:00

abstract：:Intervertebral disk disease (IVDD) is a major spine disorder in canines that causes neurological dysfunction, particularly in the thoracolumbar area. Analgesic and anti-inflammatory drugs are typically used to reduce nociceptive signals to decrease canine suffering. Bee venom (BV) has been reported to exert anti-infla...

journal_title：BioMed research international

authors： Tsai LC,Lin YW,Hsieh CL

更新日期：2015-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory disorder of the synovial membrane that results in the destruction of bone and cartilage in affected joints. Tocilizumab is a biological agent and an anti-interleukin-6 (IL-6) receptor monoclonal antibody that blocks IL-6-mediated inflammatory processes in RA patients...

journal_title：BioMed research international

authors： Yanagida M,Kawasaki M,Fujishiro M,Miura M,Ikeda K,Nozawa K,Kaneko H,Morimoto S,Takasaki Y,Ogawa H,Takamori K,Sekigawa I

更新日期：2013-01-01 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:The 3'-end processing (3'P) of each viral long terminal repeat (LTR) during human immunodeficiency virus type-1 (HIV-1) integration is a vital step in the HIV life cycle. Blocking the 3'P using 3'P inhibitor has recently become an attractive strategy for HIV-1 therapeutic intervention. Recently, we have developed a no...

journal_title：BioMed research international

authors： Sakkhachornphop S,Thongkum W,Tayapiwatana C

更新日期：2015-01-01 00:00:00

abstract：:Background. The epidemiology of atopic dermatitis (AD) in Chinese outpatients is yet to be clarified. Objectives. To investigate population-based prevalence and clinical features of AD in Chinese outpatients. Methods. A multicenter cross-sectional study was conducted in outpatients with eczema or dermatitis from 39 te...

journal_title：BioMed research international

authors： Wang X,Li LF,Zhao DY,Shen YW

更新日期：2016-01-01 00:00:00

abstract：:Growing evidence suggests that increased arginase activity affects vital bioprocesses in various systems and universally mediates the pathogenesis of numerous metabolic diseases. The adverse effects of arginase are associated with a severe decline in L-arginine bioavailability, which leads to nitric oxide synthase sub...

journal_title：BioMed research international

authors： Gilinsky MA,Polityko YK,Markel AL,Latysheva TV,Samson AO,Polis B,Naumenko SE

更新日期：2020-02-12 00:00:00

abstract：:Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play a key role in tumor...

journal_title：BioMed research international

authors： Wen J,Yin P,Li L,Kang G,Ning G,Cao Y,Gao F,Su Y,Wu Y,Zhang X

更新日期：2020-04-15 00:00:00

abstract：AIM:Cardiac rehabilitation (CR) is an important part of heart failure (HF) treatment. The aim of this paper was to evaluate if thoracic fluid content (TFC) measured by impedance cardiography (ICG) is a useful parameter for predicting the outcome of CR. METHODS:Fifty HF patients underwent clinical and noninvasive haemo...

journal_title：BioMed research international

authors： Gielerak G,Krzesiński P,Piotrowicz E,Piotrowicz R

更新日期：2013-01-01 00:00:00

abstract：:Fluconazole is a broad-spectrum triazole antifungal that is well-established as the first-line treatment for Candida albicans infections. Despite its extensive use, reports on its genotoxic/mutagenic effects are controversial; therefore, further studies are needed to better clarify such effects. African green monkey k...

journal_title：BioMed research international

authors： Correa RMDS,Mota TC,Guimarães AC,Bonfim LT,Burbano RR,Bahia MO

更新日期：2018-11-01 00:00:00

abstract：:This study described a TaqMan based real-time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = -3.249...

journal_title：BioMed research international

authors： Chen R,Chen Q,Wu X,Che Y,Wang C,Wang L,Yan S,Zhou L

更新日期：2020-01-10 00:00:00

abstract：:Brain injury such as traumatic brain injury (TBI) and stroke is the major cause of long-term disabilities in many countries. The increasing rate of brain damaged victims and the heterogeneity of impairments decrease rehabilitation effectiveness and competence resulting in higher cost of rehabilitation treatment. On th...

journal_title：BioMed research international

authors： Shapi'i A,Mat Zin NA,Elaklouk AM

更新日期：2015-01-01 00:00:00

abstract：:Dietary polyphenols present in a broad range of plant foods have been related to beneficial health effects. This review aims to update the current information about the modulation of the gut microbiota by dietary phenolic compounds, from a perspective based on the experimental approaches used. After referring to gener...

journal_title：BioMed research international

authors： Dueñas M,Muñoz-González I,Cueva C,Jiménez-Girón A,Sánchez-Patán F,Santos-Buelga C,Moreno-Arribas MV,Bartolomé B

更新日期：2015-01-01 00:00:00

abstract：:Renal dysfunction is one of the most common complications of liver cirrhosis and is associated with increased morbidity and mortality. However, no available technology can simultaneously support liver and renal function in these patients. The aim of this study was to evaluate the safety and efficacy of an artificial l...

journal_title：BioMed research international

authors： Feng L,He G,Cai L,Fu C,Li Y,Weng J,Huo X,Peng Q,Gao Y

更新日期：2018-05-24 00:00:00

abstract：:Muscle mass and strength progressively decrease with age, which results in a condition known as sarcopenia. Sarcopenia would lead to physical disability, poor quality of life, and death. Therefore, much is expected of an effective intervention for sarcopenia. Epidemiologic, clinical, and laboratory evidence suggest an...

journal_title：BioMed research international

authors： Wagatsuma A,Sakuma K

更新日期：2014-01-01 00:00:00

abstract：:GHK (glycyl-L-histidyl-L-lysine) is present in human plasma, saliva, and urine but declines with age. It is proposed that GHK functions as a complex with copper 2+ which accelerates wound healing and skin repair. GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity ...

journal_title：BioMed research international

authors： Pickart L,Vasquez-Soltero JM,Margolina A

更新日期：2015-01-01 00:00:00

abstract：:Positive results of MitraClip in terms of improvement in clinical and left ventricular parameters have been described in detail. However, long-term effects on secondary pulmonary hypertension were not investigated in a larger patient cohort to date. 70 patients with severe mitral regurgitation, additional pulmonary hy...

journal_title：BioMed research international

authors： Hünlich M,Lubos E,Beuthner BE,Puls M,Bleckmann A,Beißbarth T,Tichelbäcker T,Rudolph V,Baldus S,Schäfer U,Treede H,Von Bardeleben RS,Blankenberg S,Schillinger W

更新日期：2018-03-14 00:00:00