Co-Designing Ambient Assisted Living (AAL) Environments: Unravelling the Situated Context of Informal Dementia Care.

abstract：:The regiospecific characteristics of n-3 polyunsaturated fatty acids (PUFAs) in triacylglycerol (TAG) significantly affect the physicochemical and physiological properties of marine fish oils. In this study, the TAG molecular species composition and positional distributions of fatty acids were investigated in three ma...

journal_title：BioMed research international

authors： Zhang H,Zhao H,Zhang Y,Shen Y,Su H,Jin J,Jin Q,Wang X

更新日期：2018-07-10 00:00:00

abstract：:Polymethylmethacrylate (PMMA) bone cement is a popular bone void filler for vertebroplasty. However, the use of PMMA has some drawbacks, including the material's excessive stiffness, exothermic polymerization, and short handling time. This study aimed to create an ideal modified bone cement to solve the above-mentione...

journal_title：BioMed research international

authors： Tai CL,Lai PL,Lin WD,Tsai TT,Lee YC,Liu MY,Chen LH

更新日期：2016-01-01 00:00:00

abstract：Objective:To determine if increasing variability of blood pressure influences determination of cerebral autoregulation. Methods:A prospective observational study was performed at the ICU of a university hospital in the Netherlands. 13 comatose patients after cardiac arrest underwent baseline and intervention (tilting ...

journal_title：BioMed research international

authors： van den Brule JMD,van Kaam CR,van der Hoeven JG,Claassen JAHR,Hoedemaekers CWE

更新日期：2018-06-06 00:00:00

abstract：:Microbial strain optimisation for the overproduction of a desired phenotype has been a popular topic in recent years. Gene knockout is a genetic engineering technique that can modify the metabolism of microbial cells to obtain desirable phenotypes. Optimisation algorithms have been developed to identify the effects of...

journal_title：BioMed research international

authors： Choon YW,Mohamad MS,Deris S,Chong CK,Omatu S,Corchado JM

更新日期：2015-01-01 00:00:00

abstract：:This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal su...

journal_title：BioMed research international

authors： Chen LJ,Tong ZR,Wang Q,Zhang YQ,Liu JL

更新日期：2018-01-16 00:00:00

abstract：:Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza Bunge, has shown an antiproliferative activity on various human cancer cell lines including nasopharyngeal carcinoma cells. However, the effects of Tan IIA on human oral cancer cells are still unknown. This study aimed to invest...

journal_title：BioMed research international

authors： Tseng PY,Lu WC,Hsieh MJ,Chien SY,Chen MK

更新日期：2014-01-01 00:00:00

abstract：Background:To improve the efficacy of regenerative treatment for gingival recessions, the autologous platelet concentrates (APCs) combined with coronally advanced flap (CAF) have been investigated. However, few studies systematically assess the complementary effect of APCs in periodontal regeneration. The present study...

journal_title：BioMed research international

authors： Li R,Liu Y,Xu T,Zhao H,Hou J,Wu Y,Zhang D

更新日期：2019-07-25 00:00:00

abstract：:Sudden cardiac death is the main cause of mortality in patients affected by chronic heart failure (CHF) and with history of myocardial infarction. No study yet investigated the intra-QT phase spectral coherence as a possible tool in stratifying the arrhythmic susceptibility in patients at risk of sudden cardiac death ...

journal_title：BioMed research international

authors： Piccirillo G,Moscucci F,Persi A,Di Barba D,Pappadà MA,Rossi P,Quaglione R,Nguyen BL,Barillà F,Casenghi M,Magrì D

更新日期：2014-01-01 00:00:00

abstract：:Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...

journal_title：BioMed research international

authors： Caimmi M,Guanziroli E,Malosio M,Pedrocchi N,Vicentini F,Molinari Tosatti L,Molteni F

更新日期：2015-01-01 00:00:00

abstract：:Tau tubulin kinase 2 (TTBK2) is a kinase known to phosphorylate tau and tubulin. It has recently drawn much attention due to its involvement in multiple important cellular processes. Here, we review the current understanding of TTBK2, including its sequence, structure, binding sites, phosphorylation substrates, and ce...

journal_title：BioMed research international

authors： Liao JC,Yang TT,Weng RR,Kuo CT,Chang CW

更新日期：2015-01-01 00:00:00

abstract：:To further understand the potential expression relationships of miRNAs in miRNA gene clusters and gene families, a global analysis was performed in 4 paired tumor (breast cancer) and adjacent normal tissue samples using deep sequencing datasets. The compositions of miRNA gene clusters and families are not random, and ...

journal_title：BioMed research international

authors： Guo L,Yang S,Zhao Y,Zhang H,Wu Q,Chen F

更新日期：2014-01-01 00:00:00

abstract：:Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) a...

journal_title：BioMed research international

authors： Jones HP,Testa RR,Ross N,Seal ML,Pantelis C,Tonge B

更新日期：2015-01-01 00:00:00

abstract：Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...

journal_title：BioMed research international

authors： Białkowska J,Juranek J,Wojtkiewicz J

更新日期：2020-11-03 00:00:00

abstract：:The phytochemical substances, coumarin derivatives, have demonstrated antiresorptive bone effects by suppressing osteoclast differentiation in vitro and in vivo. Recently, we have identified 5'-hydroxy auraptene (5'-HA), a coumarin derivative isolated from Lotus lalambensis Schweinf, as a novel stimulator for osteobla...

journal_title：BioMed research international

authors： Abdallah BM,Ali EM,Elsawy H,Badr GM,Abdel-Moneim AM,Alzahrani AM

更新日期：2019-12-28 00:00:00

abstract：:Heart failure (HF) is associated with mitochondrial dysfunction and energy metabolism impairment. MicroRNAs are implicated in the development of heart failure. However, the mitochondria enriched microRNA during heart failure remains elusive. Here, we generated a pressure overload-induced early and late stage heart fai...

journal_title：BioMed research international

authors： Wang X,Song C,Zhou X,Han X,Li J,Wang Z,Shang H,Liu Y,Cao H

更新日期：2017-01-01 00:00:00

abstract：Objective:The underlying mechanisms by which cystatin C affects cardiovascular disease (CVD) are not very clear. Metabolic syndrome (MetS) is a cluster of risk factors that increase the risk of CVD. Here, we aimed to investigate the association of cystatin C with metabolic syndrome and cardiovascular outcomes in non-ST...

journal_title：BioMed research international

authors： Mao Q,Zhao N,Wang Y,Li Y,Xiang C,Li L,Zheng W,Xu S,Zhao XH

更新日期：2019-06-16 00:00:00

abstract：Background:The aims of this study were to explore the characteristics of left ventricular (LV) functional changes in subjects with or without acute mountain sickness (AMS) and their associations with AMS incidence. Methods:A total of 589 healthy men were enrolled and took a trip from Chengdu (500 m, above sea level (a...

journal_title：BioMed research international

authors： Ke J,Liu C,Yu S,Bian S,Zhang C,Yang J,Zhang J,Jin J,Rao R,Zeng Y,Huang L

更新日期：2020-11-10 00:00:00

abstract：:Flash-lamp pulsed-dye laser (FPDL) is a nonablative technology, typically used in vascular malformation therapy due to its specificity for hemoglobin. FPDL treatments were performed in a large group of patients with persistent and/or recalcitrant different dermatological lesions with cutaneous microvessel involvement....

journal_title：BioMed research international

authors： Nisticò S,Campolmi P,Moretti S,Del Duca E,Bruscino N,Conti R,Bassi A,Cannarozzo G

更新日期：2016-01-01 00:00:00

abstract：:Platelets are anuclear cells and are devoid of genomic DNA, but they are capable of de novo protein synthesis from mRNA derived from their progenitor cells, megakaryocytes. There is mounting evidence that microRNA (miRNA) plays an important role in regulating gene expression in platelets. miR-223 is the most abundant ...

journal_title：BioMed research international

authors： Shi R,Zhou X,Ji WJ,Zhang YY,Ma YQ,Zhang JQ,Li YM

更新日期：2015-01-01 00:00:00

abstract：:After earthquakes, continuing dialysis for patients with ESRD and patients suffering from crush syndrome is the serious problem. In this paper, we analyzed the failure of the provision of dialysis services observed in recent disasters and discussed how to prepare for disasters to continue dialysis therapy. Japan has f...

journal_title：BioMed research international

authors： Ikegaya N,Seki G,Ohta N

更新日期：2016-01-01 00:00:00

abstract：:Eccentric exercise is characterized by initial unfavorable effects such as subcellular muscle damage, pain, reduced fiber excitability, and initial muscle weakness. However, stretch combined with overload, as in eccentric contractions, is an effective stimulus for inducing physiological and neural adaptations to train...

journal_title：BioMed research international

authors： Hedayatpour N,Falla D

更新日期：2015-01-01 00:00:00

abstract：:The three-dimensional (3D) structures of the right atrial appendage (RAA) and left atrial appendage (LAA) were compared to clarify why thrombus formation less frequently occurs in RAA than in LAA. Morphological differences between RAA and LAA of 34 formalin-preserved cadaver hearts were investigated. Molds of RAA and ...

journal_title：BioMed research international

authors： Shinoda K,Hayashi S,Fukuoka D,Torii R,Watanabe T,Nakano T

更新日期：2016-01-01 00:00:00

abstract：:Osteoarthritis (OA) is one of the most common debilitating disorders among the elderly population. At present, there is no definite cure for the underlying causes of OA. However, adipose tissue-derived stem cells (ADSCs) in the form of stromal vascular fraction (SVF) may offer an alternative at this time. ADSCs are on...

journal_title：BioMed research international

authors： Pak J,Lee JH,Kartolo WA,Lee SH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Primary malignant spine/spinal tumors (PMSTs) are rare and life-threatening diseases. In this study, we demonstrated the advantage of volume-based 18F-FDG PET/CT metabolic parameter, metabolic tumor volume (MTV), for assessing the aggressiveness of PMSTs. MATERIALS AND METHODS:We retrospectively...

journal_title：BioMed research international

authors： Matsumoto Y,Baba S,Endo M,Setsu N,Iida K,Fukushi JI,Kawaguchi K,Okada S,Bekki H,Isoda T,Kitamura Y,Honda H,Nakashima Y

更新日期：2017-01-01 00:00:00

abstract：:A search for novel and more efficient therapeutic modalities of inflammatory bowel disease (IBD) is one of the most important tasks of contemporary medicine. The anti-inflammatory action of nicotine in IBD might be therapeutic, but its toxicity due to off-target and nonreceptor effects limited its use and prompted a s...

journal_title：BioMed research international

authors： Chernyavsky AI,Galitovskiy V,Shchepotin IB,Grando SA

更新日期：2014-01-01 00:00:00

abstract：:Cancer related fatigue (CRF) is a common and debilitating symptom that can influence quality of life (QoL) in cancer patients. The increase in survival times stresses for a better understanding of how CRF affects patients' QoL. This was a cross-sectional descriptive study with 148 randomly recruited prostate cancer pa...

journal_title：BioMed research international

authors： Charalambous A,Kouta C

更新日期：2016-01-01 00:00:00

abstract：:The establishment of the subgingival microbiota is dependent on successive colonization of the implant surface by bacterial species. Different implant surface topographies could influence the bacterial adsorption and therefore jeopardize the implant survival. This study evaluated the biofilm formation capacity of five...

journal_title：BioMed research international

authors： Pita PP,Rodrigues JA,Ota-Tsuzuki C,Miato TF,Zenobio EG,Giro G,Figueiredo LC,Gonçalves C,Gehrke SA,Cassoni A,Shibli JA

更新日期：2015-01-01 00:00:00

abstract：:Objective. To evaluate the association of -174G/C IL-6 polymorphism with failure in therapeutic response to methotrexate (MTX) or leflunomide (LEF). This prospective, observational cohort included 96 Mexican-Mestizo patients with moderate or severe rheumatoid arthritis (RA), initiating MTX or LEF, genotyped for IL-6 -...

journal_title：BioMed research international

authors： Ruiz-Padilla AJ,Gamez-Nava JI,Saldaña-Cruz AM,Murillo-Vazquez JD,Vazquez-Villegas ML,Zavaleta-Muñiz SA,Martín-Márquez BT,Ponce-Guarneros JM,Rodriguez Jimenez NA,Flores-Chavez A,Sandoval-Garcia F,Vasquez-Jimenez JC,Cardona-Muñoz E

更新日期：2016-01-01 00:00:00

abstract：:Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route ...

journal_title：BioMed research international

authors： Kundu SK,Sharma AR,Lee SS,Sharma G,Doss CG,Yagihara S,Kim DY,Nam JS,Chakraborty C

更新日期：2014-01-01 00:00:00

abstract：:Nuclear factor-kappa B (NF-κB) is the key part of multiple signal transduction of inflammation in the pathogenesis of diabetic nephropathy (DN). The ubiquitin-proteasome system is extensively involved in the regulation of the NF-κB pathway. Cylindromatosis (CYLD) has deubiquitinase activity and acts as a negative regu...

journal_title：BioMed research international

authors： Li Y,Huang W,Xu Y,Zhou L,Liang Y,Gao C,Long Y,Xu Y

更新日期：2017-01-01 00:00:00