The Emerging Role of miR-223 in Platelet Reactivity: Implications in Antiplatelet Therapy.

abstract：Introduction:Pulp regeneration, as a treatment for pulp necrosis, has significant advantages over root canal therapy for the preservation of living pulp. To date, research on pulp regeneration has mainly focused on the transplantation of pulp stem cells into the root canal, but there is still a lack of research on the ...

journal_title：BioMed research international

authors： Ke Z,Qiu Z,Xiao T,Zeng J,Zou L,Lin X,Hu X,Lin S,Lv H

更新日期：2019-07-18 00:00:00

abstract：:The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals. Si...

journal_title：BioMed research international

authors： Doke M,Avecilla V,Felty Q

更新日期：2018-01-08 00:00:00

abstract：:Following cerebral ischemia/reperfusion (I/R) injury, a series of pathophysiological processes are stimulated in both the central nervous system (CNS) and the periphery, including, but not limited to, the peripheral immune and endocrine systems and underregulation of the neuroendocrine-immune network. Glutamate (Glu) ...

journal_title：BioMed research international

authors： You J,Feng L,Xin M,Ma D,Feng J

更新日期：2018-07-19 00:00:00

abstract：:We evaluated single nucleotide polymorphism (SNP) detection via a target-capture, C-probe ligation, and RAM assay in a single-blind comparison to clinical samples that had been tested with FDA-cleared tests for up to 4 different vascular disease-related SNPs. In the RAM assay circulizable linear probes (C- or padlock ...

journal_title：BioMed research international

authors： Smith JH,Cui M,Zhang DY,Beals TP,Ye F

更新日期：2014-01-01 00:00:00

abstract：:Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions. In our study, we investigated the surface expression of ICAM-1 protein and expression of ICAM-1 mRNA in cells of the monocyte/macrophage system...

journal_title：BioMed research international

authors： Paulsen K,Tauber S,Dumrese C,Bradacs G,Simmet DM,Gölz N,Hauschild S,Raig C,Engeli S,Gutewort A,Hürlimann E,Biskup J,Unverdorben F,Rieder G,Hofmänner D,Mutschler L,Krammer S,Buttron I,Philpot C,Huge A,Lier H,Barz

更新日期：2015-01-01 00:00:00

abstract：:Our previous studies have demonstrated that diabetes-induced oxidative stress alters homeostasis of retinal nerve growth factor (NGF) resulting in accumulation of its precursor, proNGF, at the expense of NGF which plays a critical role in preserving neuronal and retinal function. This imbalance coincided with retinal ...

journal_title：BioMed research international

authors： Mysona BA,Matragoon S,Stephens M,Mohamed IN,Farooq A,Bartasis ML,Fouda AY,Shanab AY,Espinosa-Heidmann DG,El-Remessy AB

更新日期：2015-01-01 00:00:00

abstract：Background:Though there are several prognostic models, there is no protein-related prognostic model. The aim of this study is to identify possible prognostic-related proteins in bladder urothelial carcinoma and to try to predict the prognosis of bladder urothelial carcinoma based on these proteins. Methods:Profile dat...

journal_title：BioMed research international

authors： Luo Q,Zhang X

更新日期：2020-07-31 00:00:00

abstract：:Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin induces EMT and acts...

journal_title：BioMed research international

authors： Rodrigues-Diez R,Rodrigues-Diez RR,Lavoz C,Carvajal G,Droguett A,Garcia-Redondo AB,Rodriguez I,Ortiz A,Egido J,Mezzano S,Ruiz-Ortega M

更新日期：2014-01-01 00:00:00

abstract：:Background and Objective. Although minimally invasive surgical treatment of acute epidural hematoma attracts increasing attention, no generalized indications for the surgery have been adopted. This study aimed to evaluate the effects of minimally invasive surgery in acute epidural hematoma with various hematoma volume...

journal_title：BioMed research international

authors： Wang W

更新日期：2016-01-01 00:00:00

abstract：:Purpose. We aimed to study long-term outcome after pulmonary vein isolation (PVI) guided by remote magnetic navigation (RMN) and provided comparative data to outcome after manual navigation (MAN). Methods. Three hundred thirty-six patients with symptomatic paroxysmal AF underwent PVI by irrigated point-by-point radiof...

journal_title：BioMed research international

authors： Kataria V,Berte B,Vandekerckhove Y,Tavernier R,Duytschaever M

更新日期：2017-01-01 00:00:00

abstract：:The current developments of the new biological drugs targeting interleukin 5 (IL-5) and IL-5 receptor allowed to expand the treatment options for severe hypereosinophilic asthma. Clinicians will then be able to choose between antibodies targeting either circulating IL-5 or its receptor expressed on eosinophils and bas...

journal_title：BioMed research international

authors： Bagnasco D,Caminati M,Ferrando M,Aloè T,Testino E,Canonica GW,Passalacqua G

更新日期：2018-11-05 00:00:00

abstract：:In the present study, the biobleaching potential of white rot fungus Cordyceps militaris MTCC3936 was investigated. For preliminary screening, decolorization properties of C. militaris were comparatively studied using whole cells in agar-based and liquid culture systems. Preliminary investigation in liquid culture sys...

journal_title：BioMed research international

authors： Kaur B,Kumar B,Garg N,Kaur N

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Neck circumference (NC) is an anthropometric measure of obesity for upper subcutaneous adipose tissue distribution which is associated with cardiometabolic risk. This study investigated whether NC is associated with indicators of chronic kidney disease (CKD) for high cardiometabolic risk patients. METHODS:A...

journal_title：BioMed research international

authors： Liu YF,Chang ST,Lin WS,Hsu JT,Chung CM,Chang JJ,Hung KC,Chen KH,Chang CW,Chen FC,Shih YW,Chu CM

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Electrical Bioimpedance Cerebral Monitoring is assessment in real time of health of brain tissue through study of passive dielectric properties of brain. During the last two decades theory and technology have been developed in parallel with animal experiments aiming to confirm feasibility of using bioimpedance-...

journal_title：BioMed research international

authors： Seoane F,Reza Atefi S,Tomner J,Kostulas K,Lindecrantz K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The aims of this study were to evaluate the complications that occur after trauma and the characteristics of individuals who develop complications, to identify potential risk factors that increase their incidence, and finally to investigate the relationship between complications and mortality. METHODS:We di...

journal_title：BioMed research international

authors： Mondello S,Cantrell A,Italiano D,Fodale V,Mondello P,Ang D

更新日期：2014-01-01 00:00:00

abstract：:Aim. This study aimed to evaluate the reliability of 3D-TMT, previously used only for dynamic testing, in a static cephalometric evaluation. Material and Method. A group of 40 patients (20 males and 20 females; mean age 14.2 ± 1.2 years; 12-18 years old) was included in the study. The measurements obtained by the 3D-T...

journal_title：BioMed research international

authors： Mummolo S,Nota A,Marchetti E,Padricelli G,Marzo G

更新日期：2016-01-01 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：Background:The aim of this article is to present a short review of noninvasive, nonpharmacological treatment methods used in somatic illnesses that fall under the umbrella of approach called behavioral medicine. Methods:The narrative review method was applied in the study. Science paper databases, including PubMed, ha...

journal_title：BioMed research international

authors： Białkowska J,Juranek J,Wojtkiewicz J

更新日期：2020-11-03 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on lipid and glucose homeostasis. Previous study demonstrated that FGF21 might be one of the Sp1 target genes. However, the transcriptional role of Sp1 on FGF21 in adipose tissue and liver has not been reported. In this study, ...

journal_title：BioMed research international

authors： Chen S,Li H,Zhang J,Jiang S,Zhang M,Xu Y,Dong K,Yang Y,Fang Q,Jia W

更新日期：2017-01-01 00:00:00

abstract：:Surgical flaps are frequently affected by ischemia/reperfusion (I/R) injury. Calcium-sensing receptor (CaSR) and stromal cell-derived factor-1α (SDF-1α) are closely associated with myocardial I/R injury. This study was performed to evaluate the feasibility of applying SDF-1α to counteract CaSR activation-mediated I/R ...

journal_title：BioMed research international

authors： Song L,Gao LN,Wang J,Thapa S,Li Y,Zhong XB,Zhao HW,Xiang XR,Zhang FG,Ji P

更新日期：2018-01-11 00:00:00

abstract：Objective:Biomaterial research for soft tissue augmentation is an increasing topic in aesthetic medicine. Hyaluronic acid (HA) fillers are widely used for their low invasiveness and easy application to correct aesthetic defects or traumatic injuries. Some complications as acute or chronic inflammation can occur in pati...

journal_title：BioMed research international

authors： Cannella V,Altomare R,Leonardi V,Russotto L,Di Bella S,Mira F,Guercio A

更新日期：2020-05-21 00:00:00

abstract：:Thirteen individual organochlorine compounds at 3 concentrations (80, 400, and 2000 ng/mL culture medium), as well as mixtures, were assayed for the estrogen receptor (ER) activation or inhibition, using a luciferase reporter gene assay (RGA). None of the PCB 138, 153, or 180 or their mixture induced a response in the...

journal_title：BioMed research international

authors： Imazaki PH,Brose F,Jauniaux T,Das K,Muller M,Scippo ML

更新日期：2015-01-01 00:00:00

abstract：:Small renal masses have been diagnosed increasingly in recent decades, allowing surgical treatment by partial nephrectomy. This treatment option is associated with better renal function preservation, in comparison with radical nephrectomy. However, for obtaining a bloodless field during surgery, occlusion of renal art...

journal_title：BioMed research international

authors： Buys-Gonçalves GF,Abreu LAS,Gregorio BM,Sampaio FJB,Pereira-Sampaio MA,de Souza DB

更新日期：2019-02-07 00:00:00

abstract：:Birt-Hogg-Dube syndrome (BHD, OMIM#135150) is a rare disease in clinic; it is characterized by skin fibrofolliculomas, pulmonary cysts with an increased risk of recurrent pneumothorax, renal cysts, and renal neoplasms. Previous studies have demonstrated that variants in folliculin (FLCN, NM_144997) are mainly responsi...

journal_title：BioMed research international

authors： Liu L,Yang K,Wang X,Shi Z,Yang Y,Yuan Y,Guo T,Xiao X,Luo H

更新日期：2017-01-01 00:00:00

abstract：:Coronary computed tomography angiography (CCTA) has been recently evaluated for its ability to assess coronary plaque characteristics, including plaque composition. Identification of the relationship between plaque composition by CCTA and patient clinical presentations may provide insight into the pathophysiology of c...

journal_title：BioMed research international

authors： Sun Z,Xu L

更新日期：2014-01-01 00:00:00

abstract：:Tobacco smoking continues to be a leading cause of disease and mortality. Recent research has confirmed the important role of nicotinic acetylcholine receptor (nAChR) gene cluster on chromosome 15q 24-25 in nicotine dependence and smoking. In this study we tested the association of smoking initiation, age at onset of ...

journal_title：BioMed research international

authors： Buczkowski K,Sieminska A,Linkowska K,Czachowski S,Przybylski G,Jassem E,Grzybowski T

更新日期：2015-01-01 00:00:00

abstract：:Bones are the most frequent site for breast cancer cells to settle and spread (metastasise); bone metastasis is considered to have a substantial impact on the quality of patients with common cancers. However, majority of breast cancers develop insensitivity to conventional chemotherapy which provides only palliation a...

journal_title：BioMed research international

authors： Kamba AS,Ismail M,Ibrahim TA,Zakaria ZA,Gusau LH

更新日期：2014-01-01 00:00:00

abstract：:Due to expanding applications of positron emission tomography (PET) there is a demand for developing new techniques to introduce fluorine-18 (t 1/2 = 109.8 min). Considering that most novel PET tracers are sensitive biomolecules and that direct introduction of fluorine-18 often needs harsh conditions, the insertion of...

journal_title：BioMed research international

authors： Kettenbach K,Schieferstein H,Ross TL

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Recently antiangiogenic therapy with bevacizumab has shown a high but transient efficacy in glioblastoma (GBM). Indeed, GBM is one of the most angiogenic human tumors and endothelial proliferation is a hallmark of the disease. We therefore hypothesized that tumor cells may participate in endothelial prolifer...

journal_title：BioMed research international

authors： El Hallani S,Colin C,El Houfi Y,Idbaih A,Boisselier B,Marie Y,Ravassard P,Labussière M,Mokhtari K,Thomas JL,Delattre JY,Eichmann A,Sanson M

更新日期：2014-01-01 00:00:00

abstract：:Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to kee...

journal_title：BioMed research international

authors： Friedrich A,Kenar E,Kohlbacher O,Nahnsen S

更新日期：2015-01-01 00:00:00