Influence of Induced Blood Pressure Variability on the Assessment of Cerebral Autoregulation in Patients after Cardiac Arrest.

abstract：:Background and Purposes. The 320-detector row CT scanner enables visualization of whole-brain hemodynamic information (dynamic CT angiography (CTA) derived from CT perfusion scans). However, arterial image quality in dynamic CTA (dCTA) is inferior to arterial image quality in standard CTA. This study evaluates whether...

journal_title：BioMed research international

authors： Ghariq E,Mendrik AM,Willems PW,Joemai RM,Ghariq E,Vonken EJ,van Osch MJ,van Walderveen MA

更新日期：2014-01-01 00:00:00

abstract：:Farnesyl pyrophosphate synthase (FPPS) plays a vital role in the mevalonate pathway and has been shown to be involved in hypertrophy and cardiovascular diseases. Lentivirus-mediated RNA interference (RNAi) to knock down a gene of interest has become a promising new tool for the establishment of transgenic animals. The...

journal_title：BioMed research international

authors： Yang J,Zhao CZ,Chen B,Chen F,Han J,Hu SJ

更新日期：2015-01-01 00:00:00

abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

journal_title：BioMed research international

authors： Martínez MJ,Razuc M,Ponzoni I

更新日期：2019-02-17 00:00:00

abstract：:Studies pertaining to trans fatty acids (TFA), which have been implicated in development of chronic diseases, are more relevant in developing countries where nutrition transition is changing traditional habits and practices. Measuring TFA is an arduous task because of the need for fat biopsies. This study identifies a...

journal_title：BioMed research international

authors： Abraham RA,Bahl VK,Parshad R,Seenu V,Roy A,Golandaz S,Dorairaj P,Ramakrishnan L

更新日期：2013-01-01 00:00:00

abstract：:Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...

journal_title：BioMed research international

authors： Liu L,Sheng JQ,Wang MR,Gan Y,Wu XL,Liao JZ,Tian DA,He XX,Li PY

更新日期：2019-10-02 00:00:00

abstract：:Atypical chemokine receptors (ACKRs) are a subclass of G protein-coupled receptors characterized by promiscuity of ligand binding and an obvious inability to signal after ligand binding. Although some discoveries regarding this family in Homo sapiens and other species have been reported in some studies, the evolution ...

journal_title：BioMed research international

authors： Pan L,Lv J,Zhang Z,Zhang Y

更新日期：2018-09-24 00:00:00

abstract：:Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn disease (CD). Similar symptoms, but different treatment procedures for both diseases require precise diagnosis. MicroRNAs (miRNAs) are major posttranscriptional players that regulate the expression of genes during the inflammation and thus co...

journal_title：BioMed research international

authors： Guz M,Dworzański T,Jeleniewicz W,Cybulski M,Kozicka J,Stepulak A,Celiński K

更新日期：2020-07-22 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a malignant lymphoplasma-proliferative disorder with IgM monoclonal gammopathy. A recent whole-genome study identified MYD88 L265P as the key mutation in WM. We investigated MYD88 mutations in conjunction with cytogenetic study in 22 consecutive Korean WM patients. Conventional G-...

journal_title：BioMed research international

authors： Kim JA,Im K,Park SN,Kwon J,Choi Q,Hwang SM,Sekiguchi N,Yoon SS,Lee DS,Kim SY

更新日期：2014-01-01 00:00:00

abstract：:The aim of this study was to detect oral bacteremia and offer the antibiotic resistance patterns. Bacterial resistance pattern was evaluated in 50 patients. A spectrophotometer device equipped with UV and electrophoresis of the extracted samples on agarose gel for antibiogram test were used. PCR test 15 minutes after ...

journal_title：BioMed research international

authors： Rezazadeh F,Azad A,Khorami A,Modaresi F,Rezaie Z

更新日期：2020-10-01 00:00:00

abstract：:Gold nanoparticles (AuNPs) have several potential biological applications as well as excellent biocompatibility. AuNPs with surface modification using polyethylene glycol (PEG-AuNPs) can facilitate easy conjugation with various biological molecules of interest. To examine the anticancer bioactivity of PEG-AuNPs, we in...

journal_title：BioMed research international

authors： Huang YC,Yang YC,Yang KC,Shieh HR,Wang TY,Hwu Y,Chen YJ

更新日期：2014-01-01 00:00:00

abstract：:Human adipose-derived stem cells (hASCs) are an attractive cell source for therapeutic applicability in diverse fields for the repair and regeneration of damaged or malfunctioning tissues and organs. There is a growing number of cell therapies using stem cells due to their characteristics of modulation of immune syste...

journal_title：BioMed research international

authors： de Paula AC,Sáfar GA,Góes AM,Bemquerer MP,Ribeiro MA,Stumpf HO

更新日期：2015-01-01 00:00:00

abstract：:The discovery of evolutionarily conserved Atg genes required for autophagy in yeast truly revolutionized this research field and made it possible to carry out functional studies on model organisms. Insects including Drosophila are classical and still popular models to study autophagy, starting from the 1960s. This rev...

journal_title：BioMed research international

authors： Mulakkal NC,Nagy P,Takats S,Tusco R,Juhász G,Nezis IP

更新日期：2014-01-01 00:00:00

abstract：:The p53-related p63 gene encodes multiple protein isoforms, which are involved in a variety of biological activities. p63 protein stability is mainly regulated by the ubiquitin-dependent proteasomal degradation pathway. Several ubiquitin E3 ligases have been identified and some protein kinases as well as other kinds o...

journal_title：BioMed research international

authors： Li C,Xiao ZX

更新日期：2014-01-01 00:00:00

abstract：:In renal cell carcinoma, chromophobe renal cell carcinoma (ChRCC) is a distinct subtype, whose clinical manifestations often lack specificity, and the molecular mechanisms of ChRCC tumorigenesis remain generally vague. The target of this study was to discover novel biomarkers involved in ChRCC by integrated bioinforma...

journal_title：BioMed research international

authors： Zhang W,Xu Y,Zhang J,Wu J

更新日期：2020-02-07 00:00:00

abstract：:The present study obtained a germ cell-specific marker dead end (dnd) in olive flounder (Paralichthys olivaceus) named Podnd. The tissue-specific expressions of Podnd transcripts were present in testis and ovary but were not detectable in other somatic tissues detected. SISH showed that Podnd expressed only in germ ce...

journal_title：BioMed research international

authors： Wang X,Liu Q,Xiao Y,Yang Y,Wang Y,Song Z,You F,An H,Xiao Z,Xu S,Ma D,Li J

更新日期：2015-01-01 00:00:00

abstract：:Objective. This study aims to extract motor ingredients through data mining from wearable sensors in a virtual reality goal-directed shoulder rehabilitation (GDSR) system and to examine their effects toward clinical assessment. Design. A single-group before/after comparison. Setting. Outpatient research hospital. Subj...

journal_title：BioMed research international

authors： Lee SH,Yeh SC,Chan RC,Chen S,Yang G,Zheng LR

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:To evaluate HIV risk perception and its associated factors among Chinese MSM. METHODS:A cross-sectional study was conducted among MSM with an HIV negative or unknown status in Beijing, China, between 2011 and 2012. A questionnaire interview was conducted and a blood sample was collected for HIV and syphilis ...

journal_title：BioMed research international

authors： Fan W,Yin L,Qian HZ,Li D,Shao Y,Vermund SH,Ruan Y,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：:Growing evidence suggests that increased arginase activity affects vital bioprocesses in various systems and universally mediates the pathogenesis of numerous metabolic diseases. The adverse effects of arginase are associated with a severe decline in L-arginine bioavailability, which leads to nitric oxide synthase sub...

journal_title：BioMed research international

authors： Gilinsky MA,Polityko YK,Markel AL,Latysheva TV,Samson AO,Polis B,Naumenko SE

更新日期：2020-02-12 00:00:00

abstract：Objective:To compare the effectiveness of arthroscopic partial meniscectomy (APM) and physical therapy (PT) for degenerative meniscus tears. Method:We conducted a literature search through PubMed, Embase, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. Randomized controlled trials in adults...

journal_title：BioMed research international

authors： Li J,Zhu W,Gao X,Li X

更新日期：2020-03-03 00:00:00

abstract：PURPOSE:To develop a dual energy imaging method to improve the accuracy of electron density measurement with a cone-beam CT (CBCT) device. MATERIALS AND METHODS:The imaging system is the XVI CBCT system on Elekta Synergy linac. Projection data were acquired with the high and low energy X-ray, respectively, to set up a...

journal_title：BioMed research international

authors： Men K,Dai JR,Li MH,Chen XY,Zhang K,Tian Y,Huang P,Xu YJ

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was the synthesis of folic acid- (FA-) targeted polymeric micelles of Synperonic PE/F 127-cholesteryl hemisuccinate (PF127-Chol) for specific delivery of docetaxel (DTX). Targeted or nontargeted micelles loaded with DTX were prepared via dialysis method. The effects of processing variables ...

journal_title：BioMed research international

authors： Varshosaz J,Taymouri S,Hassanzadeh F,Javanmard SH,Rostami M

更新日期：2015-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is one of the major metabolic disorders that is currently threatening the world. DM is seen associated with obesity and diabetic retinopathy (DR). In the present paper we tried to evaluate the relationship between the three aliments at the gene level and further performed the molecular docking t...

journal_title：BioMed research international

authors： Rampogu S,Rampogu Lemuel M

更新日期：2016-01-01 00:00:00

abstract：:Among the different signaling molecules released during reactive gliosis occurring in Alzheimer's disease (AD), the astrocyte-derived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease. The use of pharmacological tools targeting S100B may be crucial to embank its effects and some ...

journal_title：BioMed research international

authors： Cirillo C,Capoccia E,Iuvone T,Cuomo R,Sarnelli G,Steardo L,Esposito G

更新日期：2015-01-01 00:00:00

abstract：:The differential effects of a selective kappa- (κ-) opioid receptor agonist, U50488, were elucidated by monitoring the contraction of isolated guinea pig atrial and ventricular muscles. In electrically driven left atria, U50488 in nanomolar concentration range decreased the contractile force. Norbinaltorphimine (norBN...

journal_title：BioMed research international

authors： Hung CF,Li HJ,Chang HH,Lee GA,Su MJ

更新日期：2015-01-01 00:00:00

abstract：:Abnormal expression of neuroepithelial cell transforming gene 1 (NET1) has been authenticated in many human cancers, including lung cancer. We have previously reported that NET1 functioned as an oncogene and promoted human non-small-cell lung cancer (NSCLC) growth and migration. However, the correlation between NET1 a...

journal_title：BioMed research international

authors： Ding S,Huang H,Xu Y,Shen L,Zhong C,Zheng S

更新日期：2020-01-11 00:00:00

abstract：OBJECTIVE:Cerebral white matter hyperintensity (WMH) with magnetic resonance imaging (MRI) has a potential for predicting cognitive impairment. Serum polyunsaturated fatty acid (PUFA) levels are important for evaluating the extent of atherosclerosis. We investigated whether abnormal PUFA levels affected WMH grading and...

journal_title：BioMed research international

authors： Suwa M,Yamaguchi S,Komori T,Kajimoto S,Kino M

更新日期：2015-01-01 00:00:00

abstract：:To explore the antitumor effect of hypoxia-inducible factor-1α short hairpin RNA (HIF-1α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation hepatoma were established, Wistar rats were rand...

journal_title：BioMed research international

authors： Liao Y,Luo H,He Z,Kuang Y,Chen P,Zhang X,Chen J,Wen Q,Xie Y,Ding S

更新日期：2019-02-19 00:00:00

abstract：:Bone defects are repaired using either natural or synthetic bone grafts. Poly(ϵ-caprolactone) (PCL), β-tricalcium phosphate (TCP), and poly(lactic-co-glycolic acid) (PLGA) are widely used as synthetic materials for tissue engineering. This study aimed to investigate the bone-healing capacity of PCL/PLGA/duck beak scaf...

journal_title：BioMed research international

authors： Lee JY,Son SJ,Son JS,Kang SS,Choi SH

更新日期：2016-01-01 00:00:00

abstract：:Two fullerene derivatives (fullerenes 1 and 2), bearing a hydrophilic chain on the pyrrolidinic nitrogen, were developed with the aim to deliver anticancer agents to solid tumors. These two compounds showed a significantly different behaviour on human neoplastic cell lines in vitro in respect to healthy leukocytes. In...

journal_title：BioMed research international

authors： Pacor S,Grillo A,Đorđević L,Zorzet S,Lucafò M,Da Ros T,Prato M,Sava G

更新日期：2015-01-01 00:00:00

abstract：:Angiogenesis is essential for tumor growth and metastasis. Over the last decades, a substantial progress has been achieved in defining different patterns of tumor microcirculation. Sprouting angiogenesis, the oldest model of microcirculation, is the de novo vessel formation from preexisting blood vessels. Vessel split...

journal_title：BioMed research international

authors： Alameddine RS,Hamieh L,Shamseddine A

更新日期：2014-01-01 00:00:00