Bone-Healing Capacity of PCL/PLGA/Duck Beak Scaffold in Critical Bone Defects in a Rabbit Model.

abstract：:The incidence of acute kidney injury after cardiac surgery (CS-AKI) ranges from 33% to 94% and is associated with a high incidence of morbidity and mortality. The etiology is suggested to be multifactorial and related to almost all aspects of perioperative management. Numerous studies have reported the risk factors an...

journal_title：BioMed research international

authors： Shin SR,Kim WH,Kim DJ,Shin IW,Sohn JT

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To assess glutamine/glutamate (Glx) and lactate (Lac) metabolism using proton magnetic resonance spectroscopic imaging (1H-MRS) in order to differentiate between adrenal gland nodules and masses (adenomas, pheochromocytomas, carcinomas, and metastases). MATERIALS AND METHODS:Institutional review board approval...

journal_title：BioMed research international

authors： Goldman SM,Nunes TF,Melo HJ,Dalavia C,Szejnfeld D,Kater C,Andreoni C,Szejnfeld J,Ajzen SA

更新日期：2013-01-01 00:00:00

abstract：:Any bioassay to test new chemically synthesized larvicides or phytolarvicides against Culicidae and more harmful mosquito species, such as Aedes aegypti and Aedes albopictus, which specifically transmit dengue, yellow fever, chikungunya viral fevers as well as Zika virus, or Anopheles gambiae, a vector for malaria and...

journal_title：BioMed research international

authors： Fontana JD,Ferreira RL,Zuccolotto T,de Borba Dallagassa C,Wielewski LP,Chalcoski BMS,da Silva MAN,Richardi VS,Golart J,de Melo Rodovalho C

更新日期：2020-08-29 00:00:00

abstract：:Background. The aim of this study was to assess the effects of low concentrations of H2O2 on angiogenesis of human umbilical vein endothelial cells (HUVECs) in vitro and explore the underlying mechanisms. Methods. HUVECs were cultured and stimulated with different concentrations of H2O2. Flow cytometric analysis was u...

journal_title：BioMed research international

authors： Jiang S,Zhang D,Huang H,Lei Y,Han Y,Han W

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Neck circumference (NC) is an anthropometric measure of obesity for upper subcutaneous adipose tissue distribution which is associated with cardiometabolic risk. This study investigated whether NC is associated with indicators of chronic kidney disease (CKD) for high cardiometabolic risk patients. METHODS:A...

journal_title：BioMed research international

authors： Liu YF,Chang ST,Lin WS,Hsu JT,Chung CM,Chang JJ,Hung KC,Chen KH,Chang CW,Chen FC,Shih YW,Chu CM

更新日期：2015-01-01 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:Bayesian analysis was used to estimate the pig's and herd's true prevalence of enteropathogenic Yersinia in serum samples collected from Finnish pig farms. The sensitivity and specificity of the diagnostic test were also estimated for the commercially available ELISA which is used for antibody detection against entero...

journal_title：BioMed research international

authors： Vilar MJ,Ranta J,Virtanen S,Korkeala H

更新日期：2015-01-01 00:00:00

abstract：Background:In peritoneal dialysis (PD) patients, whether angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) could protect residual renal function is still controversial. To assess the effects of ACEIs and ARBs on the residual renal function and cardiovascular (CV) events in perito...

journal_title：BioMed research international

authors： Ding L,Yang J,Li L,Yang Y

更新日期：2020-09-23 00:00:00

abstract：:Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can b...

journal_title：BioMed research international

authors： Kang J,Fan W,Deng Q,He H,Huang F

更新日期：2019-01-29 00:00:00

abstract：:Ricin is a potential biothreat agent with no approved antidote available for ricin poisoning. The aim of this study was to develop potent antibody-based antiricin antidotes. Four strong ricin resistant hybridoma clones secreting antiricin monoclonal antibodies (mAbs) were developed. All four mAbs are bound to conforma...

journal_title：BioMed research international

authors： Hu WG,Yin J,Chau D,Hu CC,Lillico D,Yu J,Negrych LM,Cherwonogrodzky JW

更新日期：2013-01-01 00:00:00

abstract：:In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic h...

journal_title：BioMed research international

authors： Muñoz C,San Francisco J,Gutiérrez B,González J

更新日期：2015-01-01 00:00:00

abstract：:Family planning coverage has improved in Ethiopia in the last decade, though fertility is still about 5.8 in the rural setup. In this paper, the major structural determinants of family planning service were analyzed using a multilevel model from 8906 individual women observation in the 2011 EDHS data. The results show...

journal_title：BioMed research international

authors： Gizachew Balew J,Cho Y,Tammy Kim C,Ko W

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIM:The sensitivity and specificity of biomarkers used for predicting peripheral neuropathy in patients with systemic lupus erythematosus (SLE) and nephritis (SLE-LN) remain unsatisfactory. This study aimed to determine the autoantibodies levels in SLE-LN patients with peripheral neuropathy. METHODS:Dat...

journal_title：BioMed research international

authors： Su YJ,Huang CR,Chang WN,Tsai NW,Kung CT,Lin WC,Huang CC,Su CM,Cheng BC,Chang YT,Lu CH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To assess whether high-molecular-weight proteins excretion predicts outcome and therapy-responsiveness in patients with FSGS and nephrotic syndrome. RESEARCH DESIGN AND METHODS:Thirty-eight patients measured at biopsy fractional excretion of IgG (FEIgG) and urinary α2-macroglobulin/creatinine ratio ( α m/C)....

journal_title：BioMed research international

authors： Bazzi C,Rizza V,Casellato D,Stivali G,Rachele G,Napodano P,Gallieni M,D'Amico G

更新日期：2013-01-01 00:00:00

abstract：:Diarrhea is a major clinical problem affecting foals up to 3 months of age. The aim of this study was to identify enteric microorganisms involved in monoinfections and coinfections and the associated virulence factors in healthy and diarrheic foals. Diarrheic (D) (n = 56) and nondiarrheic (ND) foals (n = 60) up to thr...

journal_title：BioMed research international

authors： Olivo G,Lucas TM,Borges AS,Silva RO,Lobato FC,Siqueira AK,da Silva Leite D,Brandão PE,Gregori F,de Oliveira-Filho JP,Takai S,Ribeiro MG

更新日期：2016-01-01 00:00:00

abstract：:Resveratrol has recently been used as a supplemental treatment for several neurological and nonneurological diseases. It is not known whether resveratrol has neuroprotective effect on amyotrophic lateral sclerosis (ALS). To assess the effect of resveratrol on the disease, we tested this agent on an ALS model of SOD1(G...

journal_title：BioMed research international

authors： Song L,Chen L,Zhang X,Li J,Le W

更新日期：2014-01-01 00:00:00

abstract：Objective:To explore the ability of asiatic acid to interfere with the invasion and proliferation of breast cancer cells by inhibiting WAVE3 expression and activation through the PI3K/AKT signaling pathway. Methods:The MDA-MB-231 cells with strong invasiveness were screened by transwell assay, and plasmids with high e...

journal_title：BioMed research international

authors： Gou XJ,Bai HH,Liu LW,Chen HY,Shi Q,Chang LS,Ding MM,Shi Q,Zhou MX,Chen WL,Zhang LM

更新日期：2020-02-10 00:00:00

abstract：:The acute toxicity, the antioxidant activity, and the pharmacological activity on the gastrointestinal tract of rodents of the ethanolic extract (TFEE) from the bark of Terminalia fagifolia Mart. & Zucc. (Combretaceae) and of its aqueous (TFAqF), hydroalcoholic (TFHAF), and hexanic (TFHEXF) partition fractions have be...

journal_title：BioMed research international

authors： Nunes PH,Martins Mdo C,Oliveira Rde C,Chaves MH,Sousa EA,Leite JR,Véras LM,Almeida FR

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The vasoconstrictor endothelin-1 (ET-1) has been implicated in the pathogenesis of cerebral vasospasm following subarachnoid hemorrhage (SAH). Previous results showed that CGS 26303, an endothelin converting enzyme (ECE) inhibitor, effectively prevented and reversed arterial narrowing in animal m...

journal_title：BioMed research international

authors： Wang CJ,Lee PY,Wu BN,Wu SC,Loh JK,Tsai HP,Chung CL,Kassell NF,Kwan AL

更新日期：2014-01-01 00:00:00

abstract：:Osteoarthritis (OA) is a chronic degenerative joint disease, where chondrocyte apoptosis is responsible for cartilage degeneration. Bax is a well-known proapoptotic protein of the Bcl-2 family, involved in a large number of physiological and pathological processes. However, the regulation mechanisms of Bax underlying ...

journal_title：BioMed research international

authors： Miao G,Zang X,Hou H,Sun H,Wang L,Zhang T,Tan Y,Liu W,Ye P,Gao L,Zha Z

更新日期：2019-03-12 00:00:00

abstract：:The treatment of traumatic low-degree vertebral compression fracture remains in a wide range between functional treatment, bracing, vertebroplasty, kyphoplasty, and even surgical fixation. The objective was to assess the innovation of instrumented kyphoplasty and to report the early and mid-term functional and radiolo...

journal_title：BioMed research international

authors： Descamps J,Lamerain M,Chenguel Z,Jubert P,Rousseau MA

更新日期：2019-12-10 00:00:00

abstract：:Constitutive activation of Akt is believed to be an oncogenic signal in multiple myeloma and is associated with poor patient prognosis and resistance to available treatment. The stability of Akt proteins is regulated by phosphorylating the highly conserved turn motif (TM) of these proteins and the chaperone protein HS...

journal_title：BioMed research international

authors： Zhang Y,Fu Y,Zhang F,Liu J

更新日期：2014-01-01 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a multifactorial disease characterized by progressive retinal ganglion cell death and visual field loss. It is known that alterations in intraocular pressure (IOP), blood pressure (BP), and ocular perfusion pressure (OPP) can play a significant role in the pathogenesis of the dise...

journal_title：BioMed research international

authors： Choi J,Kook MS

更新日期：2015-01-01 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：:The current data are still inconclusive in terms of a genetic component involved in the susceptibility to renal cell carcinoma. Our aim was to evaluate 40 selected candidate polymorphisms for potential association with clear cell renal cell carcinoma (ccRCC) based on independent group of 167 patients and 200 healthy c...

journal_title：BioMed research international

authors： Pośpiech E,Ligęza J,Wilk W,Gołas A,Jaszczyński J,Stelmach A,Ryś J,Blecharczyk A,Wojas-Pelc A,Jura J,Branicki W

更新日期：2015-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) features chronic inflammatory reactions of both intra- and extrapulmonary nature. Moreover, COPD is associated with abnormal glucose and lipid metabolism in patients, which influences the prognosis and chronicity of this disease. Abnormal glucose and lipid metabolism are al...

journal_title：BioMed research international

authors： Li J,Lu Y,Li N,Li P,Wang Z,Ting W,Liu X,Wu W

更新日期：2020-04-06 00:00:00

abstract：:Different animal models for peritoneal dialysis (PD) have been used in the past decades to develop PD fluids compatible with patient life and to identify markers of peritoneal fibrosis and inflammation. Only few of those studies have taken into account the importance of uraemia-induced alterations at both systemic and...

journal_title：BioMed research international

authors： Ferrantelli E,Liappas G,Keuning ED,Vila Cuenca M,González-Mateo G,Verkaik M,López-Cabrera M,Beelen RH

更新日期：2015-01-01 00:00:00

abstract：:Plantar fasciitis is a cause of chronic pain under the heel and bottom of the foot. One of the treatments to reduce pain consists of using plantar orthoses to address specific imbalances during foot placement or gait. The aim of the present study was to determine if reduction of pain with a treatment based on plantar ...

journal_title：BioMed research international

authors： Moyne-Bressand S,Dhieux C,Dousset E,Decherchi P

更新日期：2018-12-12 00:00:00

abstract：:Recent studies suggest that nucleotide-binding domain leucine-rich repeat protein 1 (NLRP1) is a pivotal factor in the inflammatory process. However, the role of NLRP1 in breast cancer pathogenesis remains unclear. The aim of this study was to examine the expression and function of NLRP1 in breast cancer. We found tha...

journal_title：BioMed research international

authors： Wei Y,Huang H,Qiu Z,Li H,Tan J,Ren G,Wang X

更新日期：2017-01-01 00:00:00

abstract：:Cancer and diabetes are among the most common diseases in western societies. Epidemiological studies have shown that diabetic patients have a significantly higher risk of developing a number of different types of cancers and that individuals with comorbidity (cancer and diabetes/prediabetes) have a poorer prognosis re...

journal_title：BioMed research international

authors： Haass NK,Nassif N,McGowan EM

更新日期：2015-01-01 00:00:00