Systemic and Ocular Hemodynamic Risk Factors in Glaucoma.

abstract：:Although a history of first-trimester recurrent spontaneous abortion (FRSA) is regarded as a risk factor in antenatal care, the characteristic of subsequent pregnancy outcome is not clearly elucidated. Here, a retrospective analysis was performed on the clinical data of 492 singleton pregnant women. 164 of them with t...

journal_title：BioMed research international

authors： Yang J,Wang Y,Wang XY,Zhao YY,Wang J,Zhao YY

更新日期：2017-01-01 00:00:00

abstract：:Alternative splicing (AS) is a major engine that drives proteome diversity in mammalian genomes and is a widespread cause of human hereditary diseases. More than 95% of genes in the human genome are alternatively spliced, and the most common type of AS is the cassette exon. Recent discoveries have demonstrated that th...

journal_title：BioMed research international

authors： Cui Y,Cai M,Stanley HE

更新日期：2017-01-01 00:00:00

abstract：:The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of developing PD in certa...

journal_title：BioMed research international

authors： Gopalai AA,Lim SY,Chua JY,Tey S,Lim TT,Mohamed Ibrahim N,Tan AH,Eow GB,Abdul Aziz Z,Puvanarajah SD,Viswanathan S,Looi I,Lim SK,Tan LP,Chong YB,Tan CT,Zhao Y,Tan EK,Ahmad-Annuar A

更新日期：2014-01-01 00:00:00

abstract：:The rising global incidence of obesity cannot be fully explained within the context of traditional risk factors such as an unhealthy diet, physical inactivity, aging, or genetics. Adipose tissue is an endocrine as well as a metabolic organ that may be susceptible to disruption by environmental estrogenic chemicals. Si...

journal_title：BioMed research international

authors： Doke M,Avecilla V,Felty Q

更新日期：2018-01-08 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：:Fluconazole is a broad-spectrum triazole antifungal that is well-established as the first-line treatment for Candida albicans infections. Despite its extensive use, reports on its genotoxic/mutagenic effects are controversial; therefore, further studies are needed to better clarify such effects. African green monkey k...

journal_title：BioMed research international

authors： Correa RMDS,Mota TC,Guimarães AC,Bonfim LT,Burbano RR,Bahia MO

更新日期：2018-11-01 00:00:00

abstract：:Colorectal cancer, a malignant neoplasm that occurs in the colorectal mucosa, is one of the most common types of gastrointestinal cancer. Colorectal cancer has been studied extensively, but the molecular mechanisms of this malignancy have not been characterized. This study identified and verified core genes associated...

journal_title：BioMed research international

authors： Xu H,Ma Y,Zhang J,Gu J,Jing X,Lu S,Fu S,Huo J

更新日期：2020-05-08 00:00:00

abstract：:Alzheimer's disease is a multifactorial neurodegenerative disease characterized by progressive cognitive dysfunction. It is the most common form of dementia. The pathologic hallmarks of the disease include extracellular amyloid plaque, intracellular neurofibrillary tangles, and oxidative stress, to mention some of the...

journal_title：BioMed research international

authors： Assefa BT,Tafere GG,Wondafrash DZ,Gidey MT

更新日期：2020-02-18 00:00:00

abstract：INTRODUCTION:The purpose of the present contribution is to perform a detailed anatomic and virtual reality three-dimensional stereoscopic study in order to test the effectiveness of the extended endoscopic endonasal approaches for selected anterior and posterior circulation aneurysms. METHODS:The study was divided in ...

journal_title：BioMed research international

authors： Di Somma A,de Notaris M,Stagno V,Serra L,Enseñat J,Alobid I,San Molina J,Berenguer J,Cappabianca P,Prats-Galino A

更新日期：2014-01-01 00:00:00

abstract：:Inflammatory bowel disease (IBD), one kind of intestinal chronic inflammatory disease, is characterized by colonic epithelial barrier injury, overproduction of proinflammatory cytokines, and fewer short-chain fatty acids (SCFAs). The present study is aimed at testing the hypothesis that resistant maltodextrin (RM), a ...

journal_title：BioMed research international

authors： Wang S,Zhang S,Huang S,Wu Z,Pang J,Wu Y,Wang J,Han D

更新日期：2020-09-16 00:00:00

abstract：:1-Deoxynojirimycin (DNJ), the main hypoglycemic constituent in mulberry (Morus alba) latex, has been extensively researched. Although there is considerable interest in the biological effects of DNJ, the roles of 1-deoxynojirimycin (DNJ) in glycometabolism and energy metabolism in insects have received little attention...

journal_title：BioMed research international

authors： Wen CW,Lin XD,Dong MJ,Deng MJ

更新日期：2016-01-01 00:00:00

abstract：:ACE inhibitory dipeptides from Xerocomus badius fermented shrimp processing waste were isolated with ethanol, macroporous resin, chloroform, and Sephadex G-10 in sequence and identified by LC-MS/MS system coupled with electrospray ionization source. Molecular docking was performed for exploring the mechanism of their ...

journal_title：BioMed research international

authors： Gao X,Li X,Yan P,Sun R,Kan G,Zhou Y

更新日期：2018-05-08 00:00:00

abstract：:Canine mammary gland tumor (CMT) is the most common tumor in intact female dog. Zerumbone (ZER) has promising anticancer properties, but plagued with poor water solubility, poor absorption, bioavailability, and delivery to target tissues. To solubilize, ZER was loaded into nanostructured lipid carrier (NLC) to produce...

journal_title：BioMed research international

authors： Foong JN,Selvarajah GT,Rasedee A,Rahman HS,How CW,Beh CY,Teo GY,Ku CL

更新日期：2018-10-15 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by bone loss. Degree of inflammation has been identified as an important initiator of skeletal damage in RA. Iguratimod (T-614) is an anti-inflammatory agent which has been reported to show the inhibitory effect of bone destruction in RA. Ho...

journal_title：BioMed research international

authors： Song J,Liu H,Zhu Q,Miao Y,Wang F,Yang F,Cheng W,Xi Y,Niu X,He D,Chen G

更新日期：2018-02-19 00:00:00

abstract：:Understanding the mechanism behind the structure of the internal cellular clock can lead to advances in the knowledge of origins of pairs of monozygotic twins and higher order multiples as well as other biological phenomena. To gain insight into this mechanism, we analyze possible cell labeling schemes that model an o...

journal_title：BioMed research international

authors： Jim C,Berkovich S

更新日期：2015-01-01 00:00:00

abstract：:Biolasol is a newly developed solution for storing the liver, pancreas, kidneys, and heart by simple hypothermia. It exhibits high efficacy in maintaining structural and functional integrity of the graft prior to its transplantation. The solution was modified by the addition of ascorbic acid (0.088g/l) and ascorbic ac...

journal_title：BioMed research international

authors： Ostróżka-Cieślik A,Dolińska B,Ryszka F

更新日期：2018-11-12 00:00:00

abstract：AIMS/INTRODUCTION:Determining the prevalence of diabetes and its cardiovascular complications and all-cause mortality in older chronic complex patients. MATERIALS AND METHODS:We carried out a multicenter retrospective study and included a randomized sample of 932 CCP people. We assessed the prevalence of diabetes acco...

journal_title：BioMed research international

authors： Clua-Espuny JL,González-Henares MA,Queralt-Tomas MLL,Campo-Tamayo W,Muria-Subirats E,Panisello-Tafalla A,Lucas-Noll J

更新日期：2017-01-01 00:00:00

abstract：:Due to anthropogenic activities the relative concentrations of cadmium and manganese have increased in the marine environment. Cephalopods are able to accumulate such metals and, as inhabitant of coastal waters, Octopus vulgaris is continuously exposed to anthropogenic activities. Since no study is available on the ef...

journal_title：BioMed research international

authors： Nicosia A,Salamone M,Mazzola S,Cuttitta A

更新日期：2015-01-01 00:00:00

abstract：Background:Several studies found that physicians develop a negative attitude toward biochemistry and genetics disciplines. Many medical schools adopt an integrated system-based curriculum supplemented with clinical correlations. Medical schools in Jordan switched to the integrated curriculum; however, studies that eval...

journal_title：BioMed research international

authors： Alfaqih MA,Khader YS,Bashir N,Nusair Z,Nuseir Q,Nusier M

更新日期：2019-11-13 00:00:00

abstract：:To establish a reliable isoproterenol induced heart dysfunction fetal rat model and understand the switches of contractile proteins, 45 pregnant rats were divided into 15 mg/kg-once, 15 mg/kg-twice, sham-operated once, sham-operated twice, and control groups. And 18 adult rats were divided into isoproterenol-treated a...

journal_title：BioMed research international

authors： Li Y,Fang J,Hua Y,Wang C,Mu D,Zhou K

更新日期：2014-01-01 00:00:00

abstract：Objectives:The mortality rate of patients with acute respiratory distress syndrome (ARDS) is high. Hence, it is crucial to identify a reliable biomarker with wide clinical applications for predicting the prognosis of patients with ARDS. This systematic review and meta-analysis was conducted to investigate the value of ...

journal_title：BioMed research international

authors： Ni Q,Li C,Lin H

更新日期：2020-04-05 00:00:00

abstract：:With the development of molecular ecology, increasing low-abundance microbial populations were detected in oil reservoirs. However, our knowledge about the oil recovery potential of these populations is lacking. In this study, the oil recovery potential of low-abundance Dietzia that accounts for less than 0.5% in micr...

journal_title：BioMed research international

authors： Gao P,Wang H,Li G,Ma T

更新日期：2019-10-02 00:00:00

abstract：Objective:To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods:CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and...

journal_title：BioMed research international

authors： Wang H,Nie P,Dong C,Li J,Huang Y,Hao D,Xu W

更新日期：2018-03-06 00:00:00

abstract：:Microalgae are a promising source of omega-3. The purpose of this study was to extract lipid with a relatively high content of eicosapentaenoic acid (EPA) from Nannochloropsis gaditana using subcritical water extraction (SWE). The effects of different temperatures (156.1-273.9°C), extraction times (6.6-23.4 minutes), ...

journal_title：BioMed research international

authors： Ho BCH,Kamal SMM,Danquah MK,Harun R

更新日期：2018-12-27 00:00:00

abstract：:The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...

journal_title：BioMed research international

authors： Martínez-Torteya A,Treviño V,Tamez-Peña JG

更新日期：2015-01-01 00:00:00

abstract：:Heat shock proteins 70 and heat shock proteins 90 (Hsp70/90) have been implicated in many crucial steps of carcinogenesis: stabilizing oncogenic proteins, inhibiting programmed cell death and replicative senescence, induction of tumor angiogenesis, and activation of the invasion and metastasis. Plenty of cancer relate...

journal_title：BioMed research international

authors： Wang H,Tan MS,Lu RC,Yu JT,Tan L

更新日期：2014-01-01 00:00:00

abstract：:Preoperative 5-fluorouracil- (5-FU-) based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, the effect of 5-FU-based chemoradiotherapy on CRC is limited due to the development of chemoradiation resistance (CRR), and the molecular mechanisms underlying this resistance are...

journal_title：BioMed research international

authors： Xiong W,Ai YQ,Li YF,Ye Q,Chen ZT,Qin JY,Liu QY,Wang H,Ju YH,Li WH,Li YF

更新日期：2017-01-01 00:00:00

abstract：:High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...

journal_title：BioMed research international

authors： Mardente S,Mari E,Massimi I,Fico F,Faggioni A,Pulcinelli F,Antonaci A,Zicari A

更新日期：2015-01-01 00:00:00

abstract：:The future development of shrimp farming needs to improve its ecoefficiency. The purpose of this study was to evaluate water quality, flows, and nitrogen balance and production parameters on a farm with interconnected pond design to improve the efficiency of the semi-intensive culture of Litopenaeus vannamei ponds. Th...

journal_title：BioMed research international

authors： Barraza-Guardado RH,Arreola-Lizárraga JA,Miranda-Baeza A,Juárez-García M,Juvera-Hoyos A,Casillas-Hernández R

更新日期：2015-01-01 00:00:00

abstract：OBJECT:Video-assisted thoracoscopic sympathectomy is a safe, effective, and minimally invasive procedure for primary hyperhidrosis. This study aims to evaluate long-term results and patients' quality of life and investigate potential variables responsible for compensatory sweating after one-stage bilateral single-port ...

journal_title：BioMed research international

authors： Ibrahim M,Menna C,Andreetti C,Ciccone AM,D'Andrilli A,Maurizi G,Pomes LM,Cassiano F,Venuta F,Rendina EA

更新日期：2013-01-01 00:00:00