Abstract:
:Microalgae are a promising source of omega-3. The purpose of this study was to extract lipid with a relatively high content of eicosapentaenoic acid (EPA) from Nannochloropsis gaditana using subcritical water extraction (SWE). The effects of different temperatures (156.1-273.9°C), extraction times (6.6-23.4 minutes), and biomass loadings (33-117 g algae/L) on the extraction yield were studied. From the optimization study using central composite design (CCD), quadratic models generated for lipid yield and EPA composition were considered to be significant models (p < 0.05). The predictive equations were also formed for lipid yield and EPA composition. The predicted optimum lipid yield and EPA composition at 236.54°C, 13.95 minutes, and 60.50 g algae/L were 18.278 wt% of total biomass and 14.036 wt% of total fatty acid methyl ester (FAME), respectively.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Ho BCH,Kamal SMM,Danquah MK,Harun Rdoi
10.1155/2018/8273581subject
Has Abstractpub_date
2018-12-27 00:00:00pages
8273581eissn
2314-6133issn
2314-6141journal_volume
2018pub_type
杂志文章abstract:PURPOSE:Fusarium, Aspergillus, and Dematiaceous are the most common fungal species causing keratitis in tropical countries. Herein we report a prospective study on fungal keratitis caused by these three fungal species. METHODOLOGY:A prospective investigation was undertaken to evaluate eyes with presumed fungal keratit...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2013/605308
更新日期:2013-01-01 00:00:00
abstract:Objectives:Patients with stage 3 medication-related osteonecrosis of the jaw (MRONJ) suffer from severe complications. Chemotherapeutic agents and targeted drugs are considered to be associated with the development of MRONJ. However, little is known regarding the association of those agents with stage 3 MRONJ. The purp...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5847429
更新日期:2020-10-15 00:00:00
abstract:Background:Urogenital schistosomiasis remains a public health problem in Tanzania. Control programs mostly target school-going children ignoring other vulnerable groups like women of child bearing age. Previous evidence has shown that women of reproductive age suffer greatest morbidities in endemic areas. This study so...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/5923025
更新日期:2020-10-23 00:00:00
abstract::[This corrects the article DOI: 10.1155/2017/7865747.]. ...
journal_title:BioMed research international
pub_type: 杂志文章,已发布勘误
doi:10.1155/2018/6348625
更新日期:2018-05-14 00:00:00
abstract:Background:Glucagon-like peptide 1 (GLP-1) hormone is an incretin hormone that is secreted in the ileum and plays a role in the pancreas to increase insulin secretion, stimulate proliferation, and prevent pancreatic β-cell apoptosis. Currently, diabetes mellitus (DM) treatment based on GLP-1 work is being developed, fo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8724824
更新日期:2019-11-11 00:00:00
abstract:BACKGROUND:It is well established that the Mediterranean and Arab populations are at high risk for thalassemias in general and for alpha-thalassemia in particular. Yet, reports on alpha-thalassemia in Lebanon are still lacking. In this study, we aim at assessing the incidence of alpha-thalassemia in the Lebanese popula...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/517679
更新日期:2015-01-01 00:00:00
abstract::Genome-wide association studies (GWAS) have extensively analyzed single SNP effects on a wide variety of common and complex diseases and found many genetic variants associated with diseases. However, there is still a large portion of the genetic variants left unexplained. This missing heritability problem might be due...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/671859
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:To study whether weaker self-esteem in adolescence is connected with smoking behavior in adulthood. METHODS:An age cohort born in 1979 responded to the Lawrence Self-Esteem Questionnaire (LAWSEQ) at the age of 16 (n = 1,072). Respondents' smoking behavior was monitored annually during adolescence and 75.3% ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/687541
更新日期:2015-01-01 00:00:00
abstract::Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1321973
更新日期:2019-04-17 00:00:00
abstract::It has been reported that many modifications occur with the increase of oxidative stress during storage in erythrocytes. In order to delay these negative changes, we evaluated whether the addition of substances likely to protect antioxidant capacity in stored blood would be useful. Therefore, we investigated the effec...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3057384
更新日期:2016-01-01 00:00:00
abstract:AIM:Cardiac rehabilitation (CR) is an important part of heart failure (HF) treatment. The aim of this paper was to evaluate if thoracic fluid content (TFC) measured by impedance cardiography (ICG) is a useful parameter for predicting the outcome of CR. METHODS:Fifty HF patients underwent clinical and noninvasive haemo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/595369
更新日期:2013-01-01 00:00:00
abstract::To explore the antitumor effect of hypoxia-inducible factor-1α short hairpin RNA (HIF-1α shRNA) delivered by ultrasound targeted microbubble destruction (UTMD) and transcatheter arterial embolization (TAE) on rats with hepatic cancer. After the models of transplantation hepatoma were established, Wistar rats were rand...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1937460
更新日期:2019-02-19 00:00:00
abstract::Hematopoietic stem cells (HSCs) are unique in their capacity to give rise to all mature cells of the immune system. For years, HSC transplantation has been used for treatment of genetic and neoplastic diseases of the hematopoietic and immune systems. The sourcing of HSCs from human umbilical cord blood has salient adv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/740892
更新日期:2013-01-01 00:00:00
abstract::Resveratrol has recently been used as a supplemental treatment for several neurological and nonneurological diseases. It is not known whether resveratrol has neuroprotective effect on amyotrophic lateral sclerosis (ALS). To assess the effect of resveratrol on the disease, we tested this agent on an ALS model of SOD1(G...
journal_title:BioMed research international
pub_type: 杂志文章,收录出版
doi:10.1155/2014/483501
更新日期:2014-01-01 00:00:00
abstract::Traumatic brain injury (TBI) is a critical public health and socioeconomic problem worldwide. The herb pair Astragali Radix (AR)-Radix Angelica Sinensis (RAS) is a common prescribed herbal formula or is added to other Chinese medicine prescriptions for traumatic brain injury (TBI) treatment. However, the underlying me...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/3951783
更新日期:2018-11-25 00:00:00
abstract::Methylmercury, organic form of mercury, can increase the number of abnormal sperm and decrease sperm concentration and testosterone levels possibly due to the damage caused by reactive species to germ and Leydig cells. Maná-cubiu (Solanum sessiliflorum Dunal) is a native fruit from Amazon rich in iron, zinc, niacin, p...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/309631
更新日期:2014-01-01 00:00:00
abstract::C-type lectins are multifunctional sugar-binding molecules expressed on dendritic cells (DCs) and macrophages that internalize antigens for processing and presentation. Macrophage galactose-type lectin 1 (MGL1) recognizes glycoconjugates expressing Lewis X structures which contain galactose residues, and it is selecti...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/615865
更新日期:2015-01-01 00:00:00
abstract::Perinatal infections have a negative impact on brain development. However, the underlying mechanisms leading to neurological impairment are not completely understood and reliable models of inflammation are urgently needed. Using phorbol-myristate-acetate as an activator of inflammation, we investigated the effect on t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/318306
更新日期:2015-01-01 00:00:00
abstract::Molecular epidemiology has revealed that Mycobacterium tuberculosis (Mtb), formerly regarded as highly conserved species, displays a considerable degree of genetic variability that can influence the outcome of the disease as well as the innate and adaptive immune response. Recent studies have demonstrated that Mtb fam...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/741309
更新日期:2014-01-01 00:00:00
abstract::Alterations in pancreatic milieu to adapt to physiological shifts occurring in conditions of obesity and metabolic syndrome (MS) have been documented, though mechanisms leading to such a state have remained elusive so far. The data presented here tries to look at the gravity of metabolic insult during the early and pr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/617569
更新日期:2013-01-01 00:00:00
abstract::Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/2935195
更新日期:2017-01-01 00:00:00
abstract::Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in periodontitis. In this study, we aimed to investigate the anti-inflammatory effects of quercetin on Porphyromonas gingivalis (P. gingivalis) ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6282635
更新日期:2019-08-20 00:00:00
abstract::Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searc...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2017/3489603
更新日期:2017-01-01 00:00:00
abstract:Background:Since the dawn of human history, foodborne diseases have been a problem for all societies, and it is an increasing public health issue worldwide. The objective of this study is to examine knowledge, practice, and attitude in food safety among college students in the city Gondar, northwest Ethiopia. Methods:...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2021/6686392
更新日期:2021-01-12 00:00:00
abstract::Preoperative 5-fluorouracil- (5-FU-) based chemoradiotherapy is a standard treatment for locally advanced colorectal cancer (CRC). However, the effect of 5-FU-based chemoradiotherapy on CRC is limited due to the development of chemoradiation resistance (CRR), and the molecular mechanisms underlying this resistance are...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/8421614
更新日期:2017-01-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is characterized by systemic end-organ damage. We investigated the involvement of IRF5, TLR-7, MECP2, STAT4, and TNFSF4 genes and TNF-α, IFN-γ, IL-2, IL-12, IL-6, and IL-10 cytokines in SLE pathogenesis and in organ damage in Jordanian patients. Blood was collected from 51 patients a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1703842
更新日期:2019-11-29 00:00:00
abstract::Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/2931402
更新日期:2018-12-26 00:00:00
abstract::Tankyrase (TNKS) plays important roles in the malignancy of several cancers such as human lung tumor, breast cancer, and hepatocellular cancer. However, its exact functions and molecular mechanisms in ovarian cancer remain unclear. In this study, we found that TNKS was aberrantly overexpressed in human ovarian cancer ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/2686340
更新日期:2019-02-20 00:00:00
abstract::Bloodstream infections are a major concern because of high levels of antibiotic consumption and of the increasing prevalence of antimicrobial resistance. Bacteraemia is identified in a small percentage of patients with signs and symptoms of sepsis. Biomarkers are widely used in clinical practice and they are useful fo...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/547818
更新日期:2014-01-01 00:00:00
abstract::Upper-limb movement analysis is important to monitor objectively rehabilitation interventions, contributing to improving the overall treatments outcomes. Simple, fast, easy-to-use, and applicable methods are required to allow routinely functional evaluation of patients with different pathologies and clinical condition...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/484131
更新日期:2015-01-01 00:00:00