The association between autoantibodies and peripheral neuropathy in lupus nephritis.

abstract：:The etiology of nephrotic syndrome is complex and ranges from primary glomerulonephritis to secondary forms. Patients with nephrotic syndrome often need immunosuppressive treatment with its side effects and may progress to end stage renal disease. This review focuses on recent advances in the treatment of primary caus...

journal_title：BioMed research international

authors： Königshausen E,Sellin L

更新日期：2017-01-01 00:00:00

abstract：:Introduction. The aim of this study was to investigate the utility of ultrasonography (US) for predicting and assessing the effectiveness of extracorporeal shock wave therapy (ESWT) in insertional Achilles tendinopathy (IAT). Methods. A total of 42 patients with an established diagnosis of chronic IAT were examined by...

journal_title：BioMed research international

authors： Cheng Y,Zhang J,Cai Y

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Novel prognostic markers are needed so newly diagnosed breast cancer patients do not undergo any unnecessary therapy. Various microarray gene expression datasets based studies have generated gene signatures to predict the prognosis outcomes, while ignoring the large amount of information contained in establi...

journal_title：BioMed research international

authors： Saini A,Hou J,Zhou W

更新日期：2014-01-01 00:00:00

abstract：:Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...

journal_title：BioMed research international

authors： Matar KM

更新日期：2013-01-01 00:00:00

abstract：:Sudden cardiac death is the main cause of mortality in patients affected by chronic heart failure (CHF) and with history of myocardial infarction. No study yet investigated the intra-QT phase spectral coherence as a possible tool in stratifying the arrhythmic susceptibility in patients at risk of sudden cardiac death ...

journal_title：BioMed research international

authors： Piccirillo G,Moscucci F,Persi A,Di Barba D,Pappadà MA,Rossi P,Quaglione R,Nguyen BL,Barillà F,Casenghi M,Magrì D

更新日期：2014-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is characterized by systemic end-organ damage. We investigated the involvement of IRF5, TLR-7, MECP2, STAT4, and TNFSF4 genes and TNF-α, IFN-γ, IL-2, IL-12, IL-6, and IL-10 cytokines in SLE pathogenesis and in organ damage in Jordanian patients. Blood was collected from 51 patients a...

journal_title：BioMed research international

authors： Uzrail AH,Assaf AM,Abdalla SS

更新日期：2019-11-29 00:00:00

abstract：:High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm, and extracellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system. Tumor cells exploit HMGB1's ability to activate intracellular pathwa...

journal_title：BioMed research international

authors： Mardente S,Mari E,Massimi I,Fico F,Faggioni A,Pulcinelli F,Antonaci A,Zicari A

更新日期：2015-01-01 00:00:00

abstract：:Bone marrow stromal cells (BMSCs) are a valuable resource for skeletal regenerative medicine because of their osteogenic potential. In spite of the very general term "stem cell," this population of cells is far from homogeneous, and different BMSCs clones have greatly different phenotypic properties and, therefore, po...

journal_title：BioMed research international

authors： Vianna VF,Bonfim DC,Cavalcanti Ados S,Fernandes MC,Kahn SA,Casado PL,Lima IC,Murray SS,Murray EJ,Duarte ME

更新日期：2013-01-01 00:00:00

abstract：:Tau tubulin kinase 2 (TTBK2) is a kinase known to phosphorylate tau and tubulin. It has recently drawn much attention due to its involvement in multiple important cellular processes. Here, we review the current understanding of TTBK2, including its sequence, structure, binding sites, phosphorylation substrates, and ce...

journal_title：BioMed research international

authors： Liao JC,Yang TT,Weng RR,Kuo CT,Chang CW

更新日期：2015-01-01 00:00:00

abstract：:In preclinical treatment of polytraumatized patients crystalloids are preferentially used. To avoid metabolic acidosis, metabolizable anions like lactate or acetate are used to replace chloride in these solutions. We here studied the effects of malated Ringer's in resuscitation of both shock severities in comparison t...

journal_title：BioMed research international

authors： Keitel J,Hussmann B,Lendemans S,de Groot H,Rohrig R

更新日期：2015-01-01 00:00:00

abstract：:Heart rate variability is a physiological feature indicating the influence of the autonomic nervous system on the heart rate. Association of the reduced heart rate variability due to myocardial infarction and the increased postinfarction mortality was first described more than thirty years ago. Many studies have unequ...

journal_title：BioMed research international

authors： Lakusic N,Mahovic D,Kruzliak P,Cerkez Habek J,Novak M,Cerovec D

更新日期：2015-01-01 00:00:00

abstract：:Molecular epidemiology has revealed that Mycobacterium tuberculosis (Mtb), formerly regarded as highly conserved species, displays a considerable degree of genetic variability that can influence the outcome of the disease as well as the innate and adaptive immune response. Recent studies have demonstrated that Mtb fam...

journal_title：BioMed research international

authors： Schierloh P,Klepp L,Vazquez C,Rocha RV,Blanco FC,Balboa L,López B,Ritacco V,Bigi F,Sasiain Mdel C

更新日期：2014-01-01 00:00:00

abstract：:Several factors, including compressive load and knee kinematics, have been shown to influence wear. External knee moments (a surrogate for load) have recently been correlated with the medial and lateral wear scar areas of an unconstrained, PCL retaining knee design. Therefore, the purpose of this study was to determin...

journal_title：BioMed research international

authors： Ngai V,Wimmer MA

更新日期：2015-01-01 00:00:00

abstract：:Contrast-induced acute kidney injury (CI-AKI) is commonly defined as a decline in kidney function occurring in a narrow time window after administration of iodinated contrast material. The incidence of AKI after contrast material administration greatly depends on the specific definition and cutoff values used. Althoug...

journal_title：BioMed research international

authors： Meinel FG,De Cecco CN,Schoepf UJ,Katzberg R

更新日期：2014-01-01 00:00:00

abstract：:Stress shielding and micromotion are two major issues which determine the success of newly designed cementless femoral stems. The correlation of experimental validation with finite element analysis (FEA) is commonly used to evaluate the stress distribution and fixation stability of the stem within the femoral canal. T...

journal_title：BioMed research international

authors： Baharuddin MY,Salleh ShH,Hamedi M,Zulkifly AH,Lee MH,Mohd Noor A,Harris AR,Abdul Majid N

更新日期：2014-01-01 00:00:00

abstract：:C-type lectins are multifunctional sugar-binding molecules expressed on dendritic cells (DCs) and macrophages that internalize antigens for processing and presentation. Macrophage galactose-type lectin 1 (MGL1) recognizes glycoconjugates expressing Lewis X structures which contain galactose residues, and it is selecti...

journal_title：BioMed research international

authors： Montero-Barrera D,Valderrama-Carvajal H,Terrazas CA,Rojas-Hernández S,Ledesma-Soto Y,Vera-Arias L,Carrasco-Yépez M,Gómez-García L,Martínez-Saucedo D,Becerra-Díaz M,Terrazas LI

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:This study aims to explore the usage of intraocular pressure measurements as the early indicator of the increase in intra-abdominal pressure. METHODS:In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients. The control group (Gro...

journal_title：BioMed research international

authors： Ece I,Vatansev C,Kucukkartallar T,Tekin A,Kartal A,Okka M

更新日期：2015-01-01 00:00:00

abstract：:Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (AI) and increased cardiovascular risk (CVR). Patients with AI receive glucocorticoid (GC) replacement therapy which can lead to varying levels of blood cortisol. It was s...

journal_title：BioMed research international

authors： Rahvar AH,Haas CS,Danneberg S,Harbeck B

更新日期：2017-01-01 00:00:00

abstract：:Guanosine is an important building block for supramolecular gels owing to the unique self-assembly property that results from the unique hydrogen bond acceptors and donor groups. Guanosine-derived supramolecular hydrogels have promise in the fields of drug delivery, targeted release, tissue engineering applications, e...

journal_title：BioMed research international

authors： Chen M,Lin W,Hong L,Ji N,Zhao H

更新日期：2019-06-13 00:00:00

abstract：:Compressive sensing (CS) offers compression of data below the Nyquist rate, making it an attractive solution in the field of medical imaging, and has been extensively used for ultrasound (US) compression and sparse recovery. In practice, CS offers a reduction in data sensing, transmission, and storage. Compressive sen...

journal_title：BioMed research international

authors： Yousufi M,Amir M,Javed U,Tayyib M,Abdullah S,Ullah H,Qureshi IM,Alimgeer KS,Akram MW,Khan KB

更新日期：2019-11-15 00:00:00

abstract：PURPOSE:To investigate whether P. acnes could induce disc degeneration and Modic changes when inoculated into the discs of rabbits. METHOD:A wild-type strain of P. acnes isolated from a patient associated with Modic change and disc degeneration was inoculated into the intervertebral discs of rabbits. Meanwhile, S. aur...

journal_title：BioMed research international

authors： Chen Z,Zheng Y,Yuan Y,Jiao Y,Xiao J,Zhou Z,Cao P

更新日期：2016-01-01 00:00:00

abstract：:The effect of crocetin (C20H24O4) on methylcholanthrene- (MCA-) induced uterine cervical cancer in mice was studied in this paper. After the mice were treated orally with crocetin, maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were examined by ELISA...

journal_title：BioMed research international

authors： Chen B,Hou ZH,Dong Z,Li CD

更新日期：2015-01-01 00:00:00

abstract：:Among other diseases characterized by the onset of cachexia, congestive heart failure takes a place of relevance, considering the high prevalence of this pathology in most European countries and in the United States, and is undergoing a rapid increase in developing countries. Actually, only few models of cardiac cache...

journal_title：BioMed research international

authors： Sala V,Gatti S,Gallo S,Medico E,Cantarella D,Cimino J,Ponzetto A,Crepaldi T

更新日期：2016-01-01 00:00:00

abstract：:Metabolomics is the sophisticated and high-throughput technology based on the entire set of metabolites which is known as the connector between genotypes and phenotypes. For any phenotypic changes, potential metabolite (biomarker) identification is very important because it provides diagnostic as well as prognostic ma...

journal_title：BioMed research international

authors： Kumar N,Hoque MA,Shahjaman M,Islam SM,Mollah MN

更新日期：2017-01-01 00:00:00

abstract：:Mitochondria, the energy-generating organelles, play a role in numerous cellular functions including adenosine triphosphate (ATP) production, cellular homeostasis, and apoptosis. Maternal inheritance of mitochondria and mitochondrial DNA (mtDNA) is universally observed in humans and most animals. In general, high leve...

journal_title：BioMed research international

authors： Song WH,Ballard JW,Yi YJ,Sutovsky P

更新日期：2014-01-01 00:00:00

abstract：:The proper functioning of a hospital computer system is an arduous work for managers and staff. However, inconsistent policies are frequent and can produce enormous problems, such as stolen information, frequent failures, and loss of the entire or part of the hospital data. This paper presents a new method named EMRlo...

journal_title：BioMed research international

authors： Martínez Monterrubio SM,Frausto Solis J,Monroy Borja R

更新日期：2015-01-01 00:00:00

abstract：:The aim of the present study was to investigate the suitability of insoluble Eudragit® water dispersions (NE, NM, RL, and RS) for direct high-shear granulation of very soluble levetiracetam in order to decrease its burst effect from HPMC K100M matrices. The process characteristics, ss-NMR analysis, in vitro dissolutio...

journal_title：BioMed research international

authors： Mašková E,Naiserová M,Kubová K,Mašek J,Pavloková S,Urbanová M,Brus J,Vysloužil J,Vetchý D

更新日期：2019-03-05 00:00:00

abstract：:This study presented the analysis of free-breathing lung tumor motion characteristics using GE 4DCT and Varian RPM systems. Tumor respiratory movement was found to be associated with GTV size, the superior-inferior tumor location in the lung, and the attachment degree to rigid structure (e.g., chest wall, vertebrae, o...

journal_title：BioMed research international

authors： Wang Y,Bao Y,Zhang L,Fan W,He H,Sun ZW,Hu X,Huang SM,Chen M,Deng XW

更新日期：2013-01-01 00:00:00

abstract：:Diesel exhaust and its particles (DEP) have been under scrutiny for health effects in humans. In the development of these effects inflammation is regarded as a key process. Overall, in vitro studies report similar DEP-induced changes in markers of inflammation, including cytokines and chemokines, as studies in vivo. I...

journal_title：BioMed research international

authors： Schwarze PE,Totlandsdal AI,Låg M,Refsnes M,Holme JA,Øvrevik J

更新日期：2013-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) and lung cancer, closely related to smoking, are major lung diseases affecting millions of individuals worldwide. The generated gas mixture of smoking is proved to contain about 4,500 components such as carbon monoxide, nicotine, oxidants, fine particulate matter, and aldeh...

journal_title：BioMed research international

authors： Hou W,Hu S,Li C,Ma H,Wang Q,Meng G,Guo T,Zhang J

更新日期：2019-06-24 00:00:00