Late adherent human bone marrow stromal cells form bone and restore the hematopoietic microenvironment in vivo.

abstract：Background:Health workers are one of the most important building blocks of the health system. High turnover rate contribute to the shortfalls and unbalanced distribution of health personnel in the health workforce. Turnover intention is the strongest predictor of actual turnover. Objective:To assess the magnitude of t...

journal_title：BioMed research international

authors： Ferede A,Kibret GD,Million Y,Simeneh MM,Belay YA,Hailemariam D

更新日期：2018-12-23 00:00:00

abstract：:Aim. In periodontology lasers have been suggested for the photodynamic therapy (PDT): such therapy can be defined as the inactivation of cells, microorganisms, or molecules induced by light and not by heat. The aim of this study was to evaluate results of PDT using a 980 nm diode laser (Wiser Doctor Smile, Lambda SPA,...

journal_title：BioMed research international

authors： Caccianiga G,Baldoni M,Ghisalberti CA,Paiusco A

更新日期：2016-01-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) therapy has been applied to a wide range of diseases with excessive immune response, including inflammatory bowel disease (IBD), owing to its powerful immunosuppression and its ability to repair tissue lesions. Different sources of MSCs show different therapeutic properties. Engineering m...

journal_title：BioMed research international

authors： Kang J,Zhang L,Luo X,Ma X,Wang G,Yang Y,Yan Y,Qian H,Zhang X,Xu W,Mao F

更新日期：2018-12-26 00:00:00

abstract：:Subtle perturbations in intraglomerular VEGF/VEGFR-2 signaling or in the influencing microenvironment can profoundly affect renal function, resulting in the apparently paradoxical observation that VEGF blockade attenuates proteinuria development in experimental diabetes despite exerting the opposite effect under other...

journal_title：BioMed research international

authors： Advani A,Connelly KA,Advani SL,Thai K,Zhang Y,Kelly DJ,Gilbert RE

更新日期：2013-01-01 00:00:00

abstract：:The p53-related p63 gene encodes multiple protein isoforms, which are involved in a variety of biological activities. p63 protein stability is mainly regulated by the ubiquitin-dependent proteasomal degradation pathway. Several ubiquitin E3 ligases have been identified and some protein kinases as well as other kinds o...

journal_title：BioMed research international

authors： Li C,Xiao ZX

更新日期：2014-01-01 00:00:00

abstract：:Pterospartum tridentatum and Mentha pulegium are largely used in Portuguese folk medicine to treat several human disorders and inflammatory processes but without any consistent evidence for those beneficial pointed properties. Thus, the aim of the current work is to evaluate its benefits and phytochemicals related to ...

journal_title：BioMed research international

authors： Aires A,Marrinhas E,Carvalho R,Dias C,Saavedra MJ

更新日期：2016-01-01 00:00:00

abstract：:Purslane, a fleshy herbaceous plant, plays a pivotal role in various preventive and therapeutic purposes. To date, no report has documented the consequence of salt stress on metabolite accumulation in purslane. Herein, we proposed an insight into the metabolic and physiological traits of purslane under saline stress e...

journal_title：BioMed research international

authors： Zaman S,Bilal M,Du H,Che S

更新日期：2020-06-17 00:00:00

abstract：:Pediatric myelodysplastic syndrome (MDS) is an uncommon disease and little is known about the molecular alterations of its development and evolution to acute myeloid leukemia (AML). The Enhancer of Zeste Homolog 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 (PCR2). It is a histone methyltransferas...

journal_title：BioMed research international

authors： de Souza Fernandez T,Fonseca Alvarenga T,Almeida Antônio de Kós E,Lamim Lovatel V,Tavares RC,da Costa ES,de Souza Fernandez C,Abdelhay E

更新日期：2019-12-10 00:00:00

abstract：:The receptor of advanced glycation end products (RAGE) and its ligands are linked to the pathogenesis of coronary artery disease (CAD), and circulating soluble receptor of advanced glycation end products (sRAGE), reflecting the RAGE activity, is suggested as a potential biomarker. Elevated sRAGE levels are reported in...

journal_title：BioMed research international

authors： Jensen LJ,Flyvbjerg A,Bjerre M

更新日期：2015-01-01 00:00:00

abstract：:Internally symmetric proteins are proteins that have a symmetrical structure in their monomeric single-chain form. Around 10-15% of the protein domains can be regarded as having some sort of internal symmetry. In this regard, we previously published SymD (symmetry detection), an algorithm that determines whether a giv...

journal_title：BioMed research international

authors： Jha A,Flurchick KM,Bikdash M,Kc DB

更新日期：2016-01-01 00:00:00

abstract：:Recently, cardiovascular disease, also known as loop circulatory system diseases or disorders, is one of the serious diseases including heart disease, stroke, atherosclerosis, myocardial infarction, hypertension, hypotension, and thrombosis. Human pregnane X receptor, PXR, plays a crucial role in exogenous and endobio...

journal_title：BioMed research international

authors： Chen KB,Chen HY,Chen KC,Chen CY

更新日期：2014-01-01 00:00:00

abstract：:How to decrease intraoperative bleeding, shorten surgical time, and increase safety in spinal surgery is an important issue. Ultrasonic bone removers and FloSeal have been proven to increase safety, reduce the surgical duration, and decrease intraoperative bleeding in skull base surgery. Therefore, we aimed to compare...

journal_title：BioMed research international

authors： Chen HT,Hsu CC,Lu ML,Chen SH,Chen JM,Wu RW

更新日期：2019-05-19 00:00:00

abstract：PURPOSE OF THE REPORT:There is a paucity of data on correlation of various imaging modalities with clinical findings in craniosynostosis. Moreover, no study has specifically reported the role of (99m)Tc-ECD SPECT in a large number of subjects with craniosynostosis. MATERIALS AND METHODS:We prospectively analyzed a coh...

journal_title：BioMed research international

authors： Barik M,Bajpai M,Das RR,Malhotra A,Panda SS,Sahoo MK,Dwivedi S

更新日期：2014-01-01 00:00:00

abstract：:This study evaluated the microtensile bond strength (μTBS) of 1-step self-etch adhesives (1-SEAs) and 2-step self-etch adhesives (2-SEAs) to pulp chamber dentin immediately after bleaching with 2 types of common bleaching techniques. Pulp chamber dentin of bovine teeth was bleached using 30% hydrogen peroxide (H2O2) s...

journal_title：BioMed research international

authors： Haruyama A,Kameyama A,Kato J,Takemoto S,Oda Y,Kawada E,Takahashi T,Furusawa M

更新日期：2016-01-01 00:00:00

abstract：:The role of non-steroidal anti-inflammatory drugs in inflammatory bowel disease is controversial, as they have been implicated in disease aggravation. Different from other cyclooxygenase inhibitors, acetylsalicylic acid (ASA) enhances the formation of anti-inflammatory and proresolution lipoxins derived from arachidon...

journal_title：BioMed research international

authors： Köhnke T,Gomolka B,Bilal S,Zhou X,Sun Y,Rothe M,Baumgart DC,Weylandt KH

更新日期：2013-01-01 00:00:00

abstract：:Colorectal cancer is the third most common form of cancer in developed countries and, despite the improvements achieved in its treatment options, remains as one of the main causes of cancer-related death. In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved...

journal_title：BioMed research international

authors： Lizarbe MA,Calle-Espinosa J,Fernández-Lizarbe E,Fernández-Lizarbe S,Robles MÁ,Olmo N,Turnay J

更新日期：2017-01-01 00:00:00

abstract：Methods:This prospective single-blinded clinical trial included 72 ASA I-II stage children aged 1-36 months with cCHD who were scheduled to undergo TTE under sedation. Children were assigned to group A (n = 37) with a previous history of cardiac surgery and group B (n = 35) with no history of cardiac surgery. Doses of ...

journal_title：BioMed research international

authors： Gu H,Song Y,Bai J

更新日期：2020-12-12 00:00:00

abstract：:(124)Iodine ((124)I) with its 4.2 d half-life is particularly attractive for in vivo detection and quantification of longer-term biological and physiological processes; the long half-life of (124)I is especially suited for prolonged time in vivo studies of high molecular weight compounds uptake. Numerous small molecul...

journal_title：BioMed research international

authors： Cascini GL,Niccoli Asabella A,Notaristefano A,Restuccia A,Ferrari C,Rubini D,Altini C,Rubini G

更新日期：2014-01-01 00:00:00

abstract：:Increasing studies have revealed that long noncoding RNAs (lncRNAs) are not transcriptional noise but play important roles in the regulation of a wide range of biological processes, and the dysregulation of lncRNA genes is associated with disease development. Alzheimer's disease (AD) is a chronic neurodegenerative dis...

journal_title：BioMed research international

authors： Wan G,Zhou W,Hu Y,Ma R,Jin S,Liu G,Jiang Q

更新日期：2016-01-01 00:00:00

abstract：:Cancer treatment is undergoing a significant revolution from "one-size-fits-all" cytotoxic therapies to tailored approaches that precisely target molecular alterations. Precision strategies for drug development and patient stratification, based on the molecular features of tumors, are the next logical step in a long h...

journal_title：BioMed research international

authors： Coyle KM,Boudreau JE,Marcato P

更新日期：2017-01-01 00:00:00

abstract：:The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this stu...

journal_title：BioMed research international

authors： Gasparini G,Saponaro G,Gasparini D,Foresta E,Azzuni C,Adduci A,Boniello R,Moro A,De Angelis P,Di Nardo F,Damato G,Doneddu P,Todaro M,Garagiola U,Pelo S

更新日期：2018-03-11 00:00:00

abstract：Background:BMPER has been reported to be associated with the biological behavior of a few malignant tumors, but the mechanism is still unclear. We aimed to detect BMPER expression in ovarian epithelial tumor tissues and its effects on their biological behaviors, as well as to elucidate the possible mechanism. Methods:...

journal_title：BioMed research international

authors： Xi Y,Nie X,Wang J,Gao L,Lin B

更新日期：2020-03-24 00:00:00

abstract：:Cardiovascular disease (CVD) is the most common cause of death in the world. Recent studies have shown an association between adrenal insufficiency (AI) and increased cardiovascular risk (CVR). Patients with AI receive glucocorticoid (GC) replacement therapy which can lead to varying levels of blood cortisol. It was s...

journal_title：BioMed research international

authors： Rahvar AH,Haas CS,Danneberg S,Harbeck B

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND AIM:Trace elements and vitamins play a vital role in human body to perform its function properly. Thalassemic patients are at risk of micronutrient deficiency. This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elemen...

journal_title：BioMed research international

authors： Sherief LM,Abd El-Salam SM,Kamal NM,El Safy O,Almalky MA,Azab SF,Morsy HM,Gharieb AF

更新日期：2014-01-01 00:00:00

abstract：:In the present study, we determined whether there is a delay in the eruption of permanent teeth (PT) among Filipino adolescents with stunting or thinness. Height, weight, and number of PT were recorded in 1554 Filipino 10- to 13-year-olds (711 boys; 843 girls). z-scores for height (HAZ) and body mass index (BMI) were ...

journal_title：BioMed research international

authors： Heinrich-Weltzien R,Zorn C,Monse B,Kromeyer-Hauschild K

更新日期：2013-01-01 00:00:00

abstract：:Tanshinone IIA (Tan IIA), an active phytochemical in the dried root of Salvia miltiorrhiza Bunge, has shown an antiproliferative activity on various human cancer cell lines including nasopharyngeal carcinoma cells. However, the effects of Tan IIA on human oral cancer cells are still unknown. This study aimed to invest...

journal_title：BioMed research international

authors： Tseng PY,Lu WC,Hsieh MJ,Chien SY,Chen MK

更新日期：2014-01-01 00:00:00

abstract：:The repair of bone defects is a big challenge in reconstructive surgery. Periosteal distraction osteogenesis (PDO), as a promising technique used for bone regeneration, forms a space between the periosteum and bone cortex to regenerate the new bone merely by distracting the periosteum. In order to investigate the infl...

journal_title：BioMed research international

authors： Zhao D,Jiang W,Wang Y,Wang C,Zhang X,Li Q,Han D

更新日期：2020-04-23 00:00:00

abstract：Purpose:To evaluate the effects of intravitreal ranibizumab (IVR) treatment on the blood flow of the optic nerve head (ONH) and of retinal vessels of the peripapillary region of eyes with diabetic macular edema (DME) assessed using laser speckle flowgraphy (LSFG). Methods:Forty eyes of 30 patients treated with IVR for...

journal_title：BioMed research international

authors： Toto L,Evangelista F,Viggiano P,Erroi E,D'Onofrio G,Libertini D,Porreca A,D'Aloisio R,Mariacristina P,Di Antonio L,Di Nicola M,Mastropasqua R

更新日期：2020-02-10 00:00:00

abstract：:Heart failure commonly results from an irreparable damage due to cardiovascular diseases (CVDs), the leading cause of morbidity and mortality in the United States. In recent years, the rapid advancements in stem cell research have garnered much praise for paving the way to novel therapies in reversing myocardial injur...

journal_title：BioMed research international

authors： Sheng CC,Zhou L,Hao J

更新日期：2013-01-01 00:00:00

abstract：:Prior to the "onset of hearing," developing cochlear inner hair cells (IHCs) and primary auditory neurons undergo experience-independent activity, which is thought to be important in retaining and refining neural connections in the absence of sound. One of the major hypotheses regarding the origin of such activity inv...

journal_title：BioMed research international

authors： Dayaratne MW,Vlajkovic SM,Lipski J,Thorne PR

更新日期：2014-01-01 00:00:00