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Intra-QT spectral coherence as a possible noninvasive marker of sustained ventricular tachycardia.

Abstract：

:Sudden cardiac death is the main cause of mortality in patients affected by chronic heart failure (CHF) and with history of myocardial infarction. No study yet investigated the intra-QT phase spectral coherence as a possible tool in stratifying the arrhythmic susceptibility in patients at risk of sudden cardiac death (SCD). We, therefore, assessed possible difference in spectral coherence between the ECG segment extending from the q wave to the T wave peak (QTp) and the one from T wave peak to the T wave end (Te) between patients with and without Holter ECG-documented sustained ventricular tachycardia (VT). None of the QT variability indexes as well as most of the coherences and RR power spectral variables significantly differed between the two groups except for the QTp-Te spectral coherence. The latter was significantly lower in patients with sustained VT than in those without (0.508 ± 0.150 versus 0.607 ± 0.150, P < 0.05). Although the responsible mechanism remains conjectural, the QTp-Te spectral coherence holds promise as a noninvasive marker predicting malignant ventricular arrhythmias.

journal_name

Biomed Res Int

journal_title

BioMed research international

authors

Piccirillo G,Moscucci F,Persi A,Di Barba D,Pappadà MA,Rossi P,Quaglione R,Nguyen BL,Barillà F,Casenghi M,Magrì D

doi

10.1155/2014/583035

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

583035

eissn

2314-6133

issn

2314-6141

journal_volume

2014

pub_type

杂志文章

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