Correlations of Expression Levels of a Panel of Genes (IRF5, STAT4, TNFSF4, MECP2, and TLR7) and Cytokine Levels (IL-2, IL-6, IL-10, IL-12, IFN-γ, and TNF-α) with Systemic Lupus Erythematosus Outcomes in Jordanian Patients.

abstract：:Atypical chemokine receptors (ACKRs) are a subclass of G protein-coupled receptors characterized by promiscuity of ligand binding and an obvious inability to signal after ligand binding. Although some discoveries regarding this family in Homo sapiens and other species have been reported in some studies, the evolution ...

journal_title：BioMed research international

authors： Pan L,Lv J,Zhang Z,Zhang Y

更新日期：2018-09-24 00:00:00

abstract：:This research assessed the seasonal variation of the chemical composition and antibacterial and anticholinesterase activities of essential oils extracted from M. longifolia leaves. The leaves organic fractions were also investigated for their biological activities and pharmacological functions. The essential oil highe...

journal_title：BioMed research international

authors： Zouari-Bouassida K,Trigui M,Makni S,Jlaiel L,Tounsi S

更新日期：2018-12-09 00:00:00

abstract：:The distribution of the induced electric field (E-field) during transcranial magnetic stimulation (TMS) depends on the individual anatomical structure of the brain as well as coil positioning. Inappropriate stimulation may degrade the efficacy of TMS or even induce adverse effects. Therefore, optimizing the E-field ac...

journal_title：BioMed research international

authors： Li C,Liu C,Yang L,He L,Wu T

更新日期：2019-11-03 00:00:00

abstract：BACKGROUND:Hypoxia-induced autophagy and muscle wasting occur in several environmental and pathological conditions. However, the molecular mechanisms underlying the effects of the hypoxia-mimetic agent CoCl2 on autophagy and muscle atrophy are still unclear. METHODS:C2C12 myotubes were exposed to increasing concentrat...

journal_title：BioMed research international

authors： Chen R,Jiang T,She Y,Xu J,Li C,Zhou S,Shen H,Shi H,Liu S

更新日期：2017-01-01 00:00:00

abstract：:The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

journal_title：BioMed research international

authors： Guevara L,Antolinos V,Palop A,Periago PM

更新日期：2015-01-01 00:00:00

abstract：:Maintaining regular blood pressure control usually requires multidrug regimens rather than monotherapy. The objective of this study was to describe the effectiveness and safety of an angiotensin-converting enzyme inhibitor and a nondihydropyridine calcium channel blocker in a single-tablet combination in patients with...

journal_title：BioMed research international

authors： Atalar E,Eskin F,Tugtekin HB,Karabulut A,Kanyilmaz S,Kirbiyik H,Ozyildiz AG

更新日期：2020-09-05 00:00:00

abstract：:Several studies report that the OPG is an important candidate gene in the pathogenesis of osteoporosis. This study aimed to detect the potential association of OPG gene polymorphisms with osteoporosis in postmenopausal women. We recruited 928 subjects containing 463 with primary postmenopausal osteoporosis and 465 hea...

journal_title：BioMed research international

authors： Wang F,Cao Y,Li F,Shan J,Wen T

更新日期：2014-01-01 00:00:00

abstract：:The incidence of acute kidney injury after cardiac surgery (CS-AKI) ranges from 33% to 94% and is associated with a high incidence of morbidity and mortality. The etiology is suggested to be multifactorial and related to almost all aspects of perioperative management. Numerous studies have reported the risk factors an...

journal_title：BioMed research international

authors： Shin SR,Kim WH,Kim DJ,Shin IW,Sohn JT

更新日期：2016-01-01 00:00:00

abstract：:The objective of this study was the synthesis of folic acid- (FA-) targeted polymeric micelles of Synperonic PE/F 127-cholesteryl hemisuccinate (PF127-Chol) for specific delivery of docetaxel (DTX). Targeted or nontargeted micelles loaded with DTX were prepared via dialysis method. The effects of processing variables ...

journal_title：BioMed research international

authors： Varshosaz J,Taymouri S,Hassanzadeh F,Javanmard SH,Rostami M

更新日期：2015-01-01 00:00:00

abstract：Objective:Primary headache and obesity are highly prevalent disorders in the general population. Although many studies have reported an association between the two, there is still no overall comprehension about this relationship. To gain a more accurate understanding in this regard, we analyzed data from a 2011 cross-s...

journal_title：BioMed research international

authors： Huang Q,Yu H,Zhang N,Guo B,Feng C,Wang S,Liang X

更新日期：2019-04-15 00:00:00

abstract：:Objective. Obesity and obstructive sleep apnea (OSA) are closely interconnected conditions both leading to high cardiovascular risk. Inactivity is frequent and physical activity programs remain difficult in these patients. We investigated the acute feasibility of two neuromuscular electrical stimulation (NMES) modalit...

journal_title：BioMed research international

authors： Vivodtzev I,Maffiuletti NA,Borel AL,Grangier A,Wuyam B,Tamisier R,Pépin JL

更新日期：2017-01-01 00:00:00

abstract：:This study aimed at clarifying the mechanism and role of survivin in hypoxia-induced multidrug resistance (MDR) of laryngeal carcinoma cells. Human laryngeal cancer cells were incubated under hypoxia or normoxia. The expression of survivin was silenced by performing RNA interference. Additionally, by Western blot and ...

journal_title：BioMed research international

authors： Xu D,Li DW,Xie J,Chen XW

更新日期：2019-04-24 00:00:00

abstract：:Type 1 diabetes (T1D), a chronic autoimmune disease, is often preceded by a preclinical phase of islet autoimmunity (IA) where the insulin-producing beta cells of the pancreas are destroyed and circulating autoantibodies can be detected. The goal of this study was to demonstrate methods for identifying exposures that ...

journal_title：BioMed research international

authors： Frederiksen BN,Kroehl M,Barón A,Lamb MM,Crume TL,Sontag MK,Rewers M,Norris JM

更新日期：2015-01-01 00:00:00

abstract：:The future development of shrimp farming needs to improve its ecoefficiency. The purpose of this study was to evaluate water quality, flows, and nitrogen balance and production parameters on a farm with interconnected pond design to improve the efficiency of the semi-intensive culture of Litopenaeus vannamei ponds. Th...

journal_title：BioMed research international

authors： Barraza-Guardado RH,Arreola-Lizárraga JA,Miranda-Baeza A,Juárez-García M,Juvera-Hoyos A,Casillas-Hernández R

更新日期：2015-01-01 00:00:00

abstract：:Subarachnoid hemorrhage (SAH) is a devastating neurological disorder. Patients with aneurysmal SAH develop secondary complications that are important causes of morbidity and mortality. Aside from secondary neurological injuries, SAH has been associated with nonneurologic medical complications, such as neurocardiogenic...

journal_title：BioMed research international

authors： Chen S,Li Q,Wu H,Krafft PR,Wang Z,Zhang JH

更新日期：2014-01-01 00:00:00

abstract：:Autophagy is a highly regulated-cell pathway for degrading long-lived proteins as well as for clearing cytoplasmic organelles. Autophagy is a key contributor to cellular homeostasis and metabolism. Warburg hypothesized that cancer growth is frequently associated with a deviation of a set of energy generation mechanism...

journal_title：BioMed research international

authors： Gonzalez CD,Alvarez S,Ropolo A,Rosenzvit C,Bagnes MF,Vaccaro MI

更新日期：2014-01-01 00:00:00

abstract：:Fatty acids (C6-C18) found in human amniotic fluid, colostrum, and maternal milk reduce behavioral indicators of experimental anxiety in adult Wistar rats. Unknown, however, is whether the anxiolytic-like effects of fatty acids provide a natural mechanism against anxiety in young offspring. The present study assessed ...

journal_title：BioMed research international

authors： Bernal-Morales B,Cueto-Escobedo J,Guillén-Ruiz G,Rodríguez-Landa JF,Contreras CM

更新日期：2017-01-01 00:00:00

abstract：Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

journal_title：BioMed research international

authors： Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

更新日期：2019-12-14 00:00:00

abstract：:The endoscopic and histopathological findings detected in Sparus aurata experimentally infected with third-stage Anisakis larvae without intermediate host are evaluated and discussed. In six fish, live nematode larvae were introduced by gastroscopy into the stomach. The first observation by endoscope, 15 days after ch...

journal_title：BioMed research international

authors： Marino F,Lanteri G,Passantino A,De Stefano C,Costa A,Gaglio G,Macrì F

更新日期：2013-01-01 00:00:00

abstract：:Despite the rapid progression of cancer pharmacotherapy, the high drug resistance of pancreatic ductal adenocarcinoma (PDA) makes it one of the most lethal malignancies. Therefore, there are high expectations associated with experimental therapies, such as electrochemotherapy (ECT). This technique involves the applica...

journal_title：BioMed research international

authors： Michel O,Kulbacka J,Saczko J,Mączyńska J,Błasiak P,Rossowska J,Rzechonek A

更新日期：2018-03-19 00:00:00

abstract：:TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

journal_title：BioMed research international

authors： Wan H,Chang S,Hu JP,Tian XH,Wang MH

更新日期：2016-01-01 00:00:00

abstract：:Cancer cells acquire unique secretome compositions that contribute to tumor development and metastasis. The aim of our study was to elucidate the biological processes involved in cervical cancer, by performing a proteomic analysis of the secretome from the following informative cervical cell lines: SiHa (HPV16+), HeLa...

journal_title：BioMed research international

authors： Kontostathi G,Zoidakis J,Makridakis M,Lygirou V,Mermelekas G,Papadopoulos T,Vougas K,Vlamis-Gardikas A,Drakakis P,Loutradis D,Vlahou A,Anagnou NP,Pappa KI

更新日期：2017-01-01 00:00:00

abstract：:For more than 30 years, heart transplantation has been a successful therapy for patients with terminal heart failure. Mechanical circulatory support (MCS) was developed as a therapy for end-stage heart failure at a time when cardiac transplantation was not yet a useful treatment modality. With the more successful outc...

journal_title：BioMed research international

authors： Anand J,Singh SK,Antoun DG,Cohn WE,Frazier OH,Mallidi HR

更新日期：2015-01-01 00:00:00

abstract：:A reliable in vivo imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. Most stem cell transplantation studies have used immunohistological staining, which does not provide information about the migration of transplanted cells in vivo in the...

journal_title：BioMed research international

authors： Kim JH,Lee HJ,Song YS

更新日期：2015-01-01 00:00:00

abstract：:Netrins, a family of laminin-related proteins, were originally identified as axonal guidance molecules. Subsequently, netrins were found to modulate various biological processes including morphogenesis, tumorogenesis, adhesion, and, recently, angiogenesis. In human placenta, the most vascularized organ, the presence o...

journal_title：BioMed research international

authors： Dakouane-Giudicelli M,Alfaidy N,de Mazancourt P

更新日期：2014-01-01 00:00:00

abstract：Objective:The current study aimed to investigate the effects of body position on the level and severity of stuttering in young adults with developmental stuttering. Methods:A total of 24 subjects (male: 17; female: 7; mean age: 24.9 ± 6.2 years) with developmental stuttering participated. The participants were asked t...

journal_title：BioMed research international

authors： Almudhi A,Zafar H,Anwer S,Alghadir A

更新日期：2019-08-05 00:00:00

abstract：Background:The well-known rubber hand paradigm induces an illusion by having participants feel the touch applied to a fake hand. In parallel, the kinesthetic mirror illusion elicits illusions of movement by moving the reflection of a participant's arm. Experimental manipulation of sensory inputs leads to emergence of t...

journal_title：BioMed research international

authors： Metral M,Gonthier C,Luyat M,Guerraz M

更新日期：2017-01-01 00:00:00

abstract：:Coronal decompensation is a common complication in Lenke 1 or 2 AIS patients after selective thoracic fusion (STF). However, the majority who developed immediately postoperative coronal decompensation experienced improvement and the related factors are not fully understood. The aim of this retrospective study was to i...

journal_title：BioMed research international

authors： Jiang H,Shao W,Xu E,Ji Z,Lin T,Meng Y,Ma J,Wang C,Gao R,Zhou X

更新日期：2018-12-09 00:00:00

abstract：Purpose:It is well known that interstitial photodynamic therapy (iPDT) of large tumors requires effective planning to ensure efficient delivery of therapeutic dose to the target tumors. This should be achieved in parallel with minimal damage to the nearby intact tissues. To that end, clinical iPDT can be attained using...

journal_title：BioMed research international

authors： Ismael FS,Amasha H,Bachir W

更新日期：2020-03-23 00:00:00

abstract：Background:The aim of our study was to investigate the impact of abdominal wall reconstruction surgery on tissue anatomy and to explore how flap surgery influences the patient's immune status. Methods:Experimental abdominal wall defects were created in 8 Sus scrofa (swine) animal models. The animals were divided into ...

journal_title：BioMed research international

authors： Popa F,Georgescu AV

更新日期：2017-01-01 00:00:00