Folated synperonic-cholesteryl hemisuccinate polymeric micelles for the targeted delivery of docetaxel in melanoma.

abstract：Background:Hypertrophic pachymeningitis (HP) is generally regarded as a rare inflammatory disease, which results in a diffuse thickening of the dura mater. We retrospectively collected data from patients with HP. Methods:A total of 16 patients with HP were included in our study. The clinical features, laboratory evalu...

journal_title：BioMed research international

authors： Bi Z,Shang K,Cao J,Su Z,Bu B,Xu S,Liu C

更新日期：2020-08-14 00:00:00

abstract：:Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundre...

journal_title：BioMed research international

authors： Alvarado-Esquivel C,Rascón-Careaga A,Hernández-Tinoco J,Corella-Madueño MA,Sánchez-Anguiano LF,Aldana-Madrid ML,Velasquez-Vega E,Quizán-Plata T,Navarro-Henze JL,Badell-Luzardo JA,Gastélum-Cano JM,Liesenfeld O

更新日期：2016-01-01 00:00:00

abstract：:Purpose. This meta-analysis is to assess the effectiveness of teriparatide in fracture healing and clinical function improvement of the osteoporotic patients. Methods. We searched PubMed, Embase, Web of Science, and the Cochrane databases for randomized and quasi-randomized controlled trials comparing teriparatide to ...

journal_title：BioMed research international

authors： Lou S,Lv H,Wang G,Zhang L,Li M,Li Z,Zhang L,Tang P

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:This study aimed to compare the effects of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, and sedation and to find out its adverse effects in children having lower abdominal surgery. METH...

journal_title：BioMed research international

authors： Saylan S,Eroglu A,Dohman D

更新日期：2014-01-01 00:00:00

abstract：:Quercetin, a natural flavonol existing in many food resources, has been reported to be an effective antimicrobial and anti-inflammatory agent for restricting the inflammation in periodontitis. In this study, we aimed to investigate the anti-inflammatory effects of quercetin on Porphyromonas gingivalis (P. gingivalis) ...

journal_title：BioMed research international

authors： Xiong G,Ji W,Wang F,Zhang F,Xue P,Cheng M,Sun Y,Wang X,Zhang T

更新日期：2019-08-20 00:00:00

abstract：:Graphene is the first 2-dimensional material and possesses a plethora of original properties. Graphene and its derivatives have exhibited a great potential in a number of fields, both medical and nonmedical. The aim of this review is to set the theoretical basis for further research in developing graphene-based endova...

journal_title：BioMed research international

authors： Patelis N,Moris D,Matheiken S,Klonaris C

更新日期：2016-01-01 00:00:00

abstract：Background:Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ALCF) is a complicated syndrome with extremely high short-term mortality. The artificial liver support system (ALSS) may improve the liver function for patients with HBV-ACLF, but the data on its short-term outcomes are insufficient in China. ...

journal_title：BioMed research international

authors： Xiao LL,Xu XW,Huang KZ,Zhao YL,Zhang LJ,Li LJ

更新日期：2019-11-29 00:00:00

abstract：:In order to understand disease pathogenesis, improve medical diagnosis, or discover effective drug targets, it is important to identify significant genes deeply involved in human disease. For this purpose, many earlier approaches attempted to prioritize candidate genes using gene expression profiles or SNP genotype da...

journal_title：BioMed research international

authors： Che J,Shin M

更新日期：2015-01-01 00:00:00

abstract：Aim:Little is known about the association between cancer antigen 125 (MUC16/CA125) concentrations and tumor diameter of patients with hepatocellular carcinoma (HCC) and low AFP levels. To fill this gap in our knowledge, we conducted a retrospective study of 427 patients with HCC with AFP ≤200 ng/mL who underwent R0 res...

journal_title：BioMed research international

authors： Zhou S,Wang Z,Li M,Wu L

更新日期：2019-09-29 00:00:00

abstract：:Calcium phosphate cement (CPC) has good release efficiency and has therefore been used as a drug delivery system for postoperative infection. The release profile of CPC has mainly been evaluated by in vitro studies, which are carried out by immersing test specimens in a relatively large amount of solvent. However, it ...

journal_title：BioMed research international

authors： Uchida K,Sugo K,Nakajima T,Nakawaki M,Takano S,Nagura N,Takaso M,Urabe K

更新日期：2018-05-15 00:00:00

abstract：Objective:The aim of this study is to explore the potential pathogenesis of juvenile dermatomyositis by bioinformatics analysis of gene chips, which would screen the hub genes, identify potential biomarkers, and reveal the development mechanism of juvenile dermatomyositis. Material and Methods:We retrieved juvenile de...

journal_title：BioMed research international

authors： Qiu CC,Su QS,Zhu SY,Liu RC

更新日期：2019-12-07 00:00:00

abstract：:In clinical endodontics, preoperative estimation of root canal curvature is crucial regarding the prevention of iatrogenic errors. Reproduction of the two-dimensional radiographic images causes certain proximal view curvatures not seen. Therefore, the present study is aimed at investigating the degree of root canal cu...

journal_title：BioMed research international

authors： Faraj BM

更新日期：2021-01-13 00:00:00

abstract：Purpose:Computer-aided diagnosis (CAD) can aid in improving diagnostic level; however, the main problem currently faced by CAD is that it cannot obtain sufficient labeled samples. To solve this problem, in this study, we adopt a generative adversarial network (GAN) approach and design a semisupervised learning algorith...

journal_title：BioMed research international

authors： Zheng G,Han G,Soomro NQ,Ma L,Zhang F,Zhao Y,Zhao X,Zhou C

更新日期：2019-04-15 00:00:00

abstract：:Introduction. The lateral lumbar interbody fusion (LLIF) surgical approach has potential advantages over other approaches but is associated with some unique neurologic risks due to the proximity of the lumbosacral plexus. The present study analyzed complications following LLIF surgical approach using a novel single fl...

journal_title：BioMed research international

authors： Nunley P,Sandhu F,Frank K,Stone M

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:The aim of our work was to investigate the causal connection between M1 and M2 macrophage phenotypes occurrence and prostate cancer, their correlation with tumor extension (ECE), and biochemical recurrence (BR). PATIENT AND METHODS:Clinical and pathological data were prospectively gathered from 93 patient...

journal_title：BioMed research international

authors： Lanciotti M,Masieri L,Raspollini MR,Minervini A,Mari A,Comito G,Giannoni E,Carini M,Chiarugi P,Serni S

更新日期：2014-01-01 00:00:00

abstract：:The aging process causes a number of changes in the skin, including oxidative stress and dyschromia. The kojic acid (KA) is iron chelator employed in treatment of skin aging, and inhibits tyrosinase, promotes depigmentation. Nanotechnology-based drug delivery systems, such as liquid crystalline systems (LCSs), can mod...

journal_title：BioMed research international

authors： Gonçalez ML,Corrêa MA,Chorilli M

更新日期：2013-01-01 00:00:00

abstract：:Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...

journal_title：BioMed research international

authors： Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A

更新日期：2015-01-01 00:00:00

abstract：:As the fifth most common cancer in men and the eighth most common cancer in women, hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, with standard chemotherapy and radiation being minimally effective in prolonging survival. Virus hepatitis, particularly HBV and HCV infection is th...

journal_title：BioMed research international

authors： Wang Z,Jin W,Jin H,Wang X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Cost sharing between beneficiaries and government is critical to attain universal health coverage. The government of Ethiopia introduced social health insurance to improve access to quality health services. Hence, HCP are the ultimate frontline service provider; their WTP for health insurance could influence...

journal_title：BioMed research international

authors： Mekonne A,Seifu B,Hailu C,Atomsa A

更新日期：2020-04-14 00:00:00

abstract：:Lung cancer is one of the leading triggers for cancer death worldwide. In this study, the relationship of the aberrantly methylated and differentially expressed genes in lung adenocarcinoma (LUAD) with cancer prognosis was investigated, and 5 feature genes were identified eventually. Specifically, we firstly downloade...

journal_title：BioMed research international

authors： Wang X,Shi D,Zhao D,Hu D

更新日期：2020-09-25 00:00:00

abstract：:Early Infantile Epileptic Encephalopathy (known as Ohtahara Syndrome) is one of the most severe and earliest forms of epilepsy, characterized by early seizures onset. It affects newborns and children between two and six years old. Among the genes that have been associated with early infantile epileptic encephalopathy,...

journal_title：BioMed research international

authors： Al Mehdi K,Fouad B,Zouhair E,Boutaina B,Yassine N,Chaimaa AEC,Najat S,Hassan R,Rachida R,Abdelhamid B,Halima N

更新日期：2019-12-17 00:00:00

abstract：:This study evaluated the microtensile bond strength (μTBS) of 1-step self-etch adhesives (1-SEAs) and 2-step self-etch adhesives (2-SEAs) to pulp chamber dentin immediately after bleaching with 2 types of common bleaching techniques. Pulp chamber dentin of bovine teeth was bleached using 30% hydrogen peroxide (H2O2) s...

journal_title：BioMed research international

authors： Haruyama A,Kameyama A,Kato J,Takemoto S,Oda Y,Kawada E,Takahashi T,Furusawa M

更新日期：2016-01-01 00:00:00

abstract：:Since the discovery of JAK2V617F tyrosine kinase-activating mutation, several genes have been found mutated in myeloproliferative neoplasms (MPNs). FLT3-ITD, NPM1, and DNMT3A mutations frequently occurred in AML patients and have been found conferred with myeloproliferative neoplasms in mouse model. Therefore, we soug...

journal_title：BioMed research international

authors： Wang M,He N,Tian T,Liu L,Yu S,Ma D

更新日期：2014-01-01 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：:Studies have found that biotin favors glucose and lipid metabolism, and medications containing biotin have been developed. Despite the use of biotin as a pharmacological agent, few studies have addressed toxicity aspects including the possible interaction with cytochrome P450 enzyme family. This study analyzed the eff...

journal_title：BioMed research international

authors： Ronquillo-Sánchez MD,Camacho-Carranza R,Fernandez-Mejia C,Hernández-Ojeda S,Elinos-Baez M,Espinosa-Aguirre JJ

更新日期：2013-01-01 00:00:00

abstract：:Pulmonary arterial hypertension (PAH) is a severe and progressive disease, a key feature of which is pulmonary vascular remodeling. Growth factors, cytokines, and lipid mediators are involved in this remodeling process. Recent reports suggest that the peroxisome proliferator-activated receptors (PPARs) play important ...

journal_title：BioMed research international

authors： Liu G,Li X,Li Y,Tang X,Xu J,Li R,Hao P,Sun Y

更新日期：2013-01-01 00:00:00

abstract：:Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive...

journal_title：BioMed research international

authors： Shi Z,Li C,Yin Y,Yang Z,Xue H,Mu N,Wang Y,Liu M,Ma H

更新日期：2018-03-22 00:00:00

abstract：:Exosomes can reach distant tissues through blood circulation to communicate directly with target cells and rapidly regulate intracellular signals. Exosomes play an important role in cardiovascular pathophysiology. Different exosomes derived from different sources, and their cargos have different mechanisms of action. ...

journal_title：BioMed research international

authors： Liang B,He X,Zhao YX,Zhang XX,Gu N

更新日期：2020-07-07 00:00:00

abstract：:L-amino acid oxidases are enzymes found in several organisms, including venoms of snakes, where they contribute to the toxicity of ophidian envenomation. Their toxicity is primarily due to enzymatic activity, but other mechanisms have been proposed recently which require further investigation. L-amino acid oxidases ex...

journal_title：BioMed research international

authors： Izidoro LF,Sobrinho JC,Mendes MM,Costa TR,Grabner AN,Rodrigues VM,da Silva SL,Zanchi FB,Zuliani JP,Fernandes CF,Calderon LA,Stábeli RG,Soares AM

更新日期：2014-01-01 00:00:00

abstract：:To better understand the molecular mechanism for the pathogenesis of follicular thyroid carcinoma (FTC), this study aimed at identifying key miRNAs and their target genes associated with FTC, as well as analyzing their interactions. Based on the gene microarray data GSE82208 and microRNA dataset GSE62054, the differen...

journal_title：BioMed research international

authors： Hu S,Liao Y,Zheng J,Gou L,Regmi A,Zafar MI,Chen L

更新日期：2019-03-28 00:00:00