Abstract:
BACKGROUND:This study aimed to compare the effects of rectal midazolam addition after applying bupivacaine and caudal anesthesia on postoperative analgesia time, the need for additional analgesics, postoperative recovery, and sedation and to find out its adverse effects in children having lower abdominal surgery. METHODS:40 children between 2 and 10 years of ASA I-II were randomized, and they received caudal anesthesia under general anesthesia. Patients underwent the application of caudal block in addition to saline and 1 mL/kg bupivacaine 0.25%. In the postoperative period, Group C (n = 20) was given 5 mL saline, and Group M (n = 20) was given 0.30 mg/kg rectal midazolam diluted with 5 mL saline. Sedation scale and postoperative pain scale (CHIPPS) of the patients were evaluated. The patients were observed for their analgesic need, first analgesic time, and adverse effects for 24 hours. RESULTS:Demographic and hemodynamic data of the two groups did not differ. Postoperative sedation scores in both groups were significantly lower compared with the preoperative period. There was no significant difference between the groups in terms of sedation and sufficient analgesia. CONCLUSIONS:We conclude that caudal anesthesia provided sufficient analgesia in peroperative and postoperative periods, and rectal midazolam addition did not create any differences. This trial is registered with ClinicalTrials.gov NCT02127489.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Saylan S,Eroglu A,Dohman Ddoi
10.1155/2014/127548subject
Has Abstractpub_date
2014-01-01 00:00:00pages
127548eissn
2314-6133issn
2314-6141journal_volume
2014pub_type
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/435818
更新日期:2013-01-01 00:00:00
abstract::Black stain is characterized as a dark line or an incomplete coalescence of dark dots localized on the cervical third of the tooth. Over the last century, the etiology of black stain has been the subject of much debate. Most of the studies concerning this issue were conducted in pediatric population. According to the ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
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abstract::Ezrin, coding protein EZR which cross-links actin filaments, overexpresses and involves invasion, metastasis, and poor prognosis in various cancers including esophageal squamous cell carcinoma (ESCC). In our previous study, Ezrin was knock down and analyzed by mRNA expression profile which has not been fully mined. In...
journal_title:BioMed research international
pub_type: 杂志文章
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abstract:Introduction:Rapid eye movement sleep behavior disorder (RBD) is characterized by dream-enacting behavior (shouting, punching, and falling out of bed) related to unpleasant dreams and loss of normal rapid eye movement (REM) sleep muscle atonia. Rapid eye movement sleep enhances learning and memory by regulating neurona...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1810836
更新日期:2020-05-15 00:00:00
abstract::The use of anaesthetic drugs in the treatment of oral aphthosis is one of the pharmaceutical possibilities that a doctor can use for the most painful forms. Normally, Lidocaine or Diclofenac is used to treat this disease, but they can be used for a very limited time and so they are of little practical use. In this stu...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/1868254
更新日期:2018-03-11 00:00:00
abstract::Plantar fasciitis is a cause of chronic pain under the heel and bottom of the foot. One of the treatments to reduce pain consists of using plantar orthoses to address specific imbalances during foot placement or gait. The aim of the present study was to determine if reduction of pain with a treatment based on plantar ...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2018/3594150
更新日期:2018-12-12 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/763715
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/905648
更新日期:2015-01-01 00:00:00
abstract::28 new pyrrolidine types of compounds as analogues for natural polyhydroxy alkaloids of codonopsinine were evaluated for their anti-MRSA activity using MIC and MBC value determination assay against a panel of S. aureus isolates. One pyrrolidine compound, MFM 501, exhibited good inhibitory activity with MIC value of 15...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/823829
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
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doi:10.1155/2015/658712
更新日期:2015-01-01 00:00:00
abstract::A reliable in vivo imaging method to localize transplanted cells and monitor their viability would enable a systematic investigation of cell therapy. Most stem cell transplantation studies have used immunohistological staining, which does not provide information about the migration of transplanted cells in vivo in the...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2015/231805
更新日期:2015-01-01 00:00:00
abstract::Obesity or maternal overnutrition during pregnancy and lactation might have long-term consequences in offspring health. Fetal programming is characterized by adaptive responses to specific environmental conditions during early life stages. Programming alters gene expression through epigenetic modifications leading to ...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2018/8061389
更新日期:2018-06-20 00:00:00
abstract::The relationship between oxidative stress and miRNA changes in placenta as a potential mechanism involved in preeclampsia (PE) is not fully elucidated. We investigated the impact of oxidative stress on miRNAs and mRNA expression profiles of genes associated with PE in villous 3A first trimester trophoblast cells expos...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/257090
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:In Mexico and other developing countries, few reports of the survival of children with acute leukaemia exist. Objective. We aimed at comparing the disease-free survival of children with acute myeloid leukaemia who, in addition to being treated with the Latin American protocol of chemotherapy and an autologou...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2015/940278
更新日期:2015-01-01 00:00:00
abstract::During vertebrate development, the lung inaugurates as an endodermal bud from the primitive foregut. Dichotomous subdivision of the bud results in arborizing airways that form the prospective gas exchanging chambers, where a thin blood-gas barrier (BGB) is established. In the mammalian lung, this proceeds through conv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/101597
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2019/8764093
更新日期:2019-08-18 00:00:00
abstract::Neutrophils comprise the first line of innate immune defense during a host-pathogen interaction. They attack microorganisms directly through three different methods, of which, phagocytosis and degranulation have been known and well-studied for decades. The formation of neutrophil extracellular traps (NETs) is the thir...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2020/4192745
更新日期:2020-02-01 00:00:00
abstract::The palmaris longus is considered a phylogenetic degenerate metacarpophalangeal joint flexor muscle in humans, a small vestigial forearm muscle; it is the most variable muscle in humans, showing variation in position, duplication, slips and could be reverted. It is frequently studied in papers about human anatomical v...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/178906
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVES:To investigate the availability of correction of mandibular plane using software for vertical measurements in cone beam computed tomography (CBCT) according to the sites of the mandible. METHODS:CBCT scans of six dry mandibles were performed at 0-, 5-, 10-, 15-, and 20-degree angles relative to CBCT scannin...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/808625
更新日期:2015-01-01 00:00:00
abstract::The main objective was to quantify the effects of five different slopes on trunk and shoulder kinematics as well as shoulder kinetic and muscular demands during manual wheelchair (MWC) propulsion on a motorized treadmill. Eighteen participants with spinal cord injury propelled their MWC at a self-selected constant spe...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/636319
更新日期:2015-01-01 00:00:00
abstract::Determination of the volumes of acute cerebral infarct in the magnetic resonance imaging harbors prognostic values. However, semiautomatic method of segmentation is time-consuming and with high interrater variability. Using diffusion weighted imaging and apparent diffusion coefficient map from patients with acute infa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/963032
更新日期:2014-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/386074
更新日期:2013-01-01 00:00:00
abstract::Recent reports of retinal stem cells being present in several locations of the adult eye have sparked great hopes that they may be used to treat the millions of people worldwide who suffer from blindness as a result of retinal disease or injury. A population of proliferative cells derived from the ciliary body epithel...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/531579
更新日期:2013-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/175721
更新日期:2014-01-01 00:00:00
abstract::How to decrease intraoperative bleeding, shorten surgical time, and increase safety in spinal surgery is an important issue. Ultrasonic bone removers and FloSeal have been proven to increase safety, reduce the surgical duration, and decrease intraoperative bleeding in skull base surgery. Therefore, we aimed to compare...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6286258
更新日期:2019-05-19 00:00:00
abstract::Vitamin D deficiency is associated with a number of human disorders, including cardiovascular disease, cancer, diabetes, frailty, and infections. Since an association between vitamin D and migraine has also been recently speculated, we performed an electronic search on Medline, Scopus, and Web of Science using the key...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/827635
更新日期:2014-01-01 00:00:00
abstract:Objective:To investigate the prevalence of infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) among ICU admission patients in central China and develop a reliable prediction model. Methods:Five hundred and seven consecutive ICU admission patients with Klebsiella pneumoniae (KP) infection were enrolled...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9767313
更新日期:2019-03-27 00:00:00
abstract::Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/5497402
更新日期:2016-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/618021
更新日期:2015-01-01 00:00:00
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journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/179568
更新日期:2014-01-01 00:00:00