Black stain and dental caries: a review of the literature.

abstract：:Muscular dystrophies (MDs) are a heterogeneous group of diseases, caused by mutations in different components of sarcolemma, extracellular matrix, or enzymes. Inflammation and innate or adaptive immune response activation are prominent features of MDs. Various therapies under development are directed toward rescuing t...

journal_title：BioMed research international

authors： Farini A,Sitzia C,Erratico S,Meregalli M,Torrente Y

更新日期：2014-01-01 00:00:00

abstract：:Recent studies have shown that sumoylation is a posttranslational modification involved in regulation of the transforming growth factor-β (TGF-β) signaling pathway, which plays a critical role in renal fibrosis in diabetic nephropathy (DN). However, the role of sumoylation in the regulation of TGF-β signaling in DN is...

journal_title：BioMed research international

authors： Zhou X,Gao C,Huang W,Yang M,Chen G,Jiang L,Gou F,Feng H,Ai N,Xu Y

更新日期：2014-01-01 00:00:00

abstract：:Diarrhea is a major clinical problem affecting foals up to 3 months of age. The aim of this study was to identify enteric microorganisms involved in monoinfections and coinfections and the associated virulence factors in healthy and diarrheic foals. Diarrheic (D) (n = 56) and nondiarrheic (ND) foals (n = 60) up to thr...

journal_title：BioMed research international

authors： Olivo G,Lucas TM,Borges AS,Silva RO,Lobato FC,Siqueira AK,da Silva Leite D,Brandão PE,Gregori F,de Oliveira-Filho JP,Takai S,Ribeiro MG

更新日期：2016-01-01 00:00:00

abstract：:The biological age (BA) equation is a prediction model that utilizes an algorithm to combine various biological markers of ageing. Different from traditional concepts, the BA equation does not emphasize the importance of a golden index but focuses on using indices of vital organs to represent the senescence of whole b...

journal_title：BioMed research international

authors： Jia L,Zhang W,Jia R,Zhang H,Chen X

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:An elevated neutrophil-to-lymphocyte ratio (NLR) has been suggested to be associated with a poor prognosis in several cancers. We evaluated the utility of an elevated NLR as a biomarker to predict the prognosis of metastatic castration-resistant prostate cancer (mCRPC) patients treated with ...

journal_title：BioMed research international

authors： Uemura K,Kawahara T,Yamashita D,Jikuya R,Abe K,Tatenuma T,Yokomizo Y,Izumi K,Teranishi JI,Makiyama K,Yumura Y,Kishida T,Udagawa K,Kobayashi K,Miyoshi Y,Yao M,Uemura H

更新日期：2017-01-01 00:00:00

abstract：:Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...

journal_title：BioMed research international

authors： Liu L,Sheng JQ,Wang MR,Gan Y,Wu XL,Liao JZ,Tian DA,He XX,Li PY

更新日期：2019-10-02 00:00:00

abstract：:Natural plant extracts contain a variety of phenolic compounds which are assigned various biological activities. Our work aims to make a quantitative and qualitative characterization of the Zest (ZL) and the Flesh (FL) of lemon (Citrus limon), to valorize the pharmacological uses of lemon, by evaluating in vitro activ...

journal_title：BioMed research international

authors： Makni M,Jemai R,Kriaa W,Chtourou Y,Fetoui H

更新日期：2018-01-15 00:00:00

abstract：:This study aimed to summarize the clinical features, diagnosis, and treatment of Chiari malformation type I- (CM-1-) associated syringobulbia. We performed a literature review of CM-1-associated syringobulbia in PubMed, Ovid MEDLINE, and Web of Science databases. Our concerns were the clinical features, radiologic pre...

journal_title：BioMed research international

authors： Shen J,Shen J,Huang K,Wu Y,Pan J,Zhan R

更新日期：2019-03-19 00:00:00

abstract：PURPOSE:To identify an effective method to prevent myopia progression by characterizing the regulation of matrix metalloproteinase- (MMP-) 2 expression and its secretion from scleral fibroblasts and retinal pigment epithelium (RPE) cells by miR-29a. METHODS:The effects of miR-29a on the growth of scleral fibroblasts a...

journal_title：BioMed research international

authors： Zhang Y,Hu DN,Zhu Y,Sun H,Gu P,Zhu D,Zhou J

更新日期：2017-01-01 00:00:00

abstract：Purpose:To detect the responsiveness and predictive ability of the Chinese version Action Research Arm Test (C-ARAT) in participants within the first 3 months after cerebral infarction. Methods:Ninety-seven individuals (75 men, mean age 59.87 ± 10.94 years) with a first cerebral infarction were enrolled in this study....

journal_title：BioMed research international

authors： Zhao JL,Zhang T,Xu ZQ,Ding MH,Leng Y,Bian RH,Mao YR,Huang DF

更新日期：2019-10-07 00:00:00

abstract：:This review postulates the role of transforming growth factor-beta (TGF-β) and insulin-like growth factor (IGF-I/IGF-II) signaling in stromal cells during prostate carcinogenesis and progression. It is known that stromal cells have a reciprocal relationship to the adjacent epithelial cells in the maintenance of struct...

journal_title：BioMed research international

authors： Lee C,Jia Z,Rahmatpanah F,Zhang Q,Zi X,McClelland M,Mercola D

更新日期：2014-01-01 00:00:00

abstract：:In order to understand disease pathogenesis, improve medical diagnosis, or discover effective drug targets, it is important to identify significant genes deeply involved in human disease. For this purpose, many earlier approaches attempted to prioritize candidate genes using gene expression profiles or SNP genotype da...

journal_title：BioMed research international

authors： Che J,Shin M

更新日期：2015-01-01 00:00:00

abstract：:Ablative therapies have been utilized with increasing frequency for the treatment of Barrett's esophagus with and without dysplasia. Multiple modalities are available for topical ablation of the esophagus, but radiofrequency ablation (RFA) remains the most commonly used. There have been significant advances in techniq...

journal_title：BioMed research international

authors： Tuttle R,Nurkin SJ,Hochwald SN

更新日期：2014-01-01 00:00:00

abstract：Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...

journal_title：BioMed research international

authors： Zhou J,Xie Z,Cui P,Su Q,Zhang Y,Luo L,Li Z,Ye L,Liang H,Huang J

更新日期：2020-05-23 00:00:00

abstract：:The purpose of this study was to investigate the impact of polishing methods on the bonding effectiveness and durability of different resin cements to dentin. The dentin surfaces were either treated with a fine-grit diamond bur (polishing A) or further polished by polishing disks (polishing B), and then they were bond...

journal_title：BioMed research international

authors： Ren L,Li M,Pan Y,Meng X

更新日期：2018-02-28 00:00:00

abstract：BACKGROUND:Apoptosis and matrix metalloproteinase (MMP-9) are capable of hydrolysing components of the extracellular matrix and weakening the fetal membranes which leads to eventual rupture, a key process of human parturition. The aim of this study was to determine the effect of supracervical apposition and spontaneous...

journal_title：BioMed research international

authors： Chai M,Walker SP,Riley C,Rice GE,Permezel M,Lappas M

更新日期：2013-01-01 00:00:00

abstract：Introduction:Baseline neutrophil-to-lymphocyte ratio (NLR) has been repeatedly reported as a significant prognostic factor in advanced cancer patients. We explored whether changes in NLR may predict outcome of advanced cancer patients enrolled into phase 1 trials and treated with PD-1/PD-L1 inhibitors. Patients and Me...

journal_title：BioMed research international

authors： Moschetta M,Uccello M,Kasenda B,Mak G,McClelland A,Boussios S,Forster M,Arkenau HT

更新日期：2017-01-01 00:00:00

abstract：:Several studies report that the OPG is an important candidate gene in the pathogenesis of osteoporosis. This study aimed to detect the potential association of OPG gene polymorphisms with osteoporosis in postmenopausal women. We recruited 928 subjects containing 463 with primary postmenopausal osteoporosis and 465 hea...

journal_title：BioMed research international

authors： Wang F,Cao Y,Li F,Shan J,Wen T

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND AND AIM:Trace elements and vitamins play a vital role in human body to perform its function properly. Thalassemic patients are at risk of micronutrient deficiency. This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elemen...

journal_title：BioMed research international

authors： Sherief LM,Abd El-Salam SM,Kamal NM,El Safy O,Almalky MA,Azab SF,Morsy HM,Gharieb AF

更新日期：2014-01-01 00:00:00

abstract：:Background. Whether additional benefit can be achieved with the use of L-carnitine (L-C) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of L-C treatment in CHF patients. Methods. Pubmed, Ovid Emba...

journal_title：BioMed research international

authors： Song X,Qu H,Yang Z,Rong J,Cai W,Zhou H

更新日期：2017-01-01 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：:We developed a computational method to identify NAD- and FAD-binding sites in proteins. First, we extracted from the Protein Data Bank structures of proteins that bind to at least one of these ligands. NAD-/FAD-binding residue templates were then constructed by identifying binding residues through the ligand-binding d...

journal_title：BioMed research international

authors： Lu CH,Yu CS,Lin YF,Chen JY

更新日期：2015-01-01 00:00:00

abstract：:Abdominal pregnancy is a very rare form of ectopic pregnancy, associated with high morbidity and mortality for both fetus and mother. It is, and often, seen in poor resource nations, where early diagnosis is often a major challenge due to poor prenatal care and lack of medical resources. An advanced abdominal pregnanc...

journal_title：BioMed research international

authors： Dabiri T,Marroquin GA,Bendek B,Agamasu E,Mikhail M

更新日期：2014-01-01 00:00:00

abstract：:Thirteen individual organochlorine compounds at 3 concentrations (80, 400, and 2000 ng/mL culture medium), as well as mixtures, were assayed for the estrogen receptor (ER) activation or inhibition, using a luciferase reporter gene assay (RGA). None of the PCB 138, 153, or 180 or their mixture induced a response in the...

journal_title：BioMed research international

authors： Imazaki PH,Brose F,Jauniaux T,Das K,Muller M,Scippo ML

更新日期：2015-01-01 00:00:00

abstract：:Enteric fever caused by Salmonella enterica is a life-threatening systemic illness of gastrointestinal tract especially in tropical countries. Antimicrobial therapy is generally indicated but resistance towards commonly used antibiotics has limited their therapeutic usefulness. Therefore, we aimed to determine the ant...

journal_title：BioMed research international

authors： Khanal PR,Satyal D,Bhetwal A,Maharjan A,Shakya S,Tandukar S,Parajuli NP

更新日期：2017-01-01 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：:Polyketide belongs to a family of abundant natural products typically produced by the filamentous soil bacteria Streptomyces. Similar to the biosynthesis of most secondary metabolites produced in the Streptomyces species, polyketide compounds are synthesized through tight regulatory networks in the cell, and thus extr...

journal_title：BioMed research international

authors： Nah JH,Kim HJ,Lee HN,Lee MJ,Choi SS,Kim ES

更新日期：2013-01-01 00:00:00

abstract：:Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...

journal_title：BioMed research international

authors： Ceccarini MR,Vannini S,Cataldi S,Moretti M,Villarini M,Fioretti B,Albi E,Beccari T,Codini M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Wear-related failures and instabilities are frequent failure mechanisms of total knee replacements. High-conforming designs may provide additional stability for the joint. This study analyzes the effects of a ligamentous insufficiency on the stability and the wear behavior of a high-conforming knee design. ...

journal_title：BioMed research international

authors： Reinders J,Sonntag R,Kretzer JP

更新日期：2014-01-01 00:00:00

abstract：:Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundre...

journal_title：BioMed research international

authors： Alvarado-Esquivel C,Rascón-Careaga A,Hernández-Tinoco J,Corella-Madueño MA,Sánchez-Anguiano LF,Aldana-Madrid ML,Velasquez-Vega E,Quizán-Plata T,Navarro-Henze JL,Badell-Luzardo JA,Gastélum-Cano JM,Liesenfeld O

更新日期：2016-01-01 00:00:00