Estrogenic evaluation and organochlorine identification in blubber of North Sea harbour porpoise (Phocoena phocoena) stranded on the North Sea coast.

Abstract:

:Thirteen individual organochlorine compounds at 3 concentrations (80, 400, and 2000 ng/mL culture medium), as well as mixtures, were assayed for the estrogen receptor (ER) activation or inhibition, using a luciferase reporter gene assay (RGA). None of the PCB 138, 153, or 180 or their mixture induced a response in the RGA. o,p'-DDT was the most potent xenoestrogen from the DDT group, inducing a response already at 80 ng/mL. From the HCH and HCB group, only β-HCH (at 400 and 2000 ng/mL) and δ-HCH (at 2000 ng/mL) displayed estrogenic activities. These 13 organochlorines were determined by GC-MS in 12 samples of North Sea harbor porpoise blubber. The PCBs were the main contaminants. Within each group, PCB 153 (6.0 × 10(2)~4.2 × 10(4) μg/kg), p,p'-DDE (5.1 × 10(2)~8.6 × 10(3) μg/kg), and HCB (7.6 × 10(1)~1.5 × 10(3) μg/kg) were the compounds found in highest concentrations. The hormonal activity of the porpoise blubber samples was also assayed in RGA, where two samples showed estrogenic activity, seven samples showed antiestrogenic activity, and one sample showed both estrogenic and antiestrogenic activity. Our results suggest that the 13 POPs measured by GC-MS in the samples cannot explain alone the estrogenicity of the extracts.

journal_name

Biomed Res Int

authors

Imazaki PH,Brose F,Jauniaux T,Das K,Muller M,Scippo ML

doi

10.1155/2015/438295

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

438295

eissn

2314-6133

issn

2314-6141

journal_volume

2015

pub_type

杂志文章
  • Effects of Antiacid Therapy on Granuloma after Transoral Type IV-VI Cordectomy in Patients with Early-Stage Glottic Cancer.

    abstract:Objective:To investigate whether preventive administration of a proton pump inhibitor (PPI) can reduce the occurrence and development of traumatic granuloma (TG) following type IV-VI cordectomy. Methods:We retrospectively analyzed the status of postoperative granulomas in 37 patients who underwent type IV-VI cordectom...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/4178376

    authors: Jin X,Niu Y,Gu W,Wang J

    更新日期:2020-08-10 00:00:00

  • Mineral and Phytochemical Profiles and Antioxidant Activity of Herbal Material from Two Temperate Astragalus Species.

    abstract::Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/6318630

    authors: Butkutė B,Dagilytė A,Benetis R,Padarauskas A,Cesevičienė J,Olšauskaitė V,Lemežienė N

    更新日期:2018-01-21 00:00:00

  • Coadministration of Nematophagous Fungi for Biological Control over Nematodes in Bovine in the South-Eastern Brazil.

    abstract::This study compared the coadministration among the three nematode predatory fungi, Duddingtonia flagrans, Monacrosporium thaumasium, and Arthrobotrys robusta, in the biological control of cattle gastrointestinal nematodiasis in comparison with the use of the fungus D. flagrans alone. Five groups consisting of eight Gi...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/2934674

    authors: Luns FD,Assis RCL,Silva LPC,Ferraz CM,Braga FR,de Araújo JV

    更新日期:2018-03-26 00:00:00

  • Environmental Kuznets curve analysis of the economic development and nonpoint source pollution in the Ningxia Yellow River irrigation districts in China.

    abstract::This study applies the environmental Kuznets curve to test the relationship between the regional economic growth and the different types of agricultural nonpoint source pollution loads in the Ningxia Yellow River irrigation area by using the Johnes export coefficient method. Results show that the pollution load genera...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/267968

    authors: Mao C,Zhai N,Yang J,Feng Y,Cao Y,Han X,Ren G,Yang G,Meng QX

    更新日期:2013-01-01 00:00:00

  • High Prevalence of Leptotrichia amnionii, Atopobium vaginae, Sneathia sanguinegens, and Factor 1 Microbes and Association of Spontaneous Abortion among Korean Women.

    abstract::Objective. The purpose of this study was to (i) determine the cervical microbial composition in different abortion samples and to (ii) investigate the correlation between spontaneous abortion and cervical microbes in Korean women. Methods. We collected cervical swabs from women who had never undergone abortion (N = 36...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/5435089

    authors: Seo SS,Arokiyaraj S,Kim MK,Oh HY,Kwon M,Kong JS,Shin MK,Yu YL,Lee JK

    更新日期:2017-01-01 00:00:00

  • Hereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment?

    abstract::Endometrial carcinoma is the most common gynecological tumor worldwide. It can be the presenting malignancy, acting as the harbinger, of an undiagnosed hereditary syndrome. Up to 50% of females with Lynch syndrome present in this manner. Differentiation between Lynch, Muir-Torre, and Cowden syndromes can at times be c...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2015/219012

    authors: Wong A,Ngeow J

    更新日期:2015-01-01 00:00:00

  • Does the adult human ciliary body epithelium contain "true" retinal stem cells?

    abstract::Recent reports of retinal stem cells being present in several locations of the adult eye have sparked great hopes that they may be used to treat the millions of people worldwide who suffer from blindness as a result of retinal disease or injury. A population of proliferative cells derived from the ciliary body epithel...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/531579

    authors: Frøen R,Johnsen EO,Nicolaissen B,Facskó A,Petrovski G,Moe MC

    更新日期:2013-01-01 00:00:00

  • Cilostazol Improves Proangiogenesis Functions in Human Early Endothelial Progenitor Cells through the Stromal Cell-Derived Factor System and Hybrid Therapy Provides a Synergistic Effect In Vivo.

    abstract::This study investigated the effect of cilostazol on proangiogenesis functions in human early endothelial progenitor cells (EPCs) in vitro and the therapeutic implication of hybrid therapy with cilostazol and human early EPCs in vivo. Cilostazol significantly increased colony-forming units and enhanced differentiation ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2016/3639868

    authors: Tseng SY,Chao TH,Li YH,Cho CL

    更新日期:2016-01-01 00:00:00

  • Biological activities and pharmacokinetics of praeruptorins from Peucedanum species: a systematic review.

    abstract::Praeruptorins belonging to the angular-type pyranocoumarins are bioactive constituents that have been isolated from some Peucedanum species such as P. praeruptorum, which is used in traditional Chinese medicine for treatment of cold, cough, upper respiratory infections, and so forth. Many reports have demonstrated tha...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2013/343808

    authors: Sarkhail P,Shafiee A,Sarkheil P

    更新日期:2013-01-01 00:00:00

  • Effects of a pragmatic lifestyle intervention for reducing body mass in obese adults with obstructive sleep apnoea: a randomised controlled trial.

    abstract::This study investigated the effects of a pragmatic lifestyle intervention in obese adults with continuous positive airway pressure-treated obstructive sleep apnoea hypopnoea syndrome (OSAHS). Sixty patients were randomised 1 : 1 to either a 12-week lifestyle intervention or an advice-only control group. The interventi...

    journal_title:BioMed research international

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1155/2014/102164

    authors: Moss J,Tew GA,Copeland RJ,Stout M,Billings CG,Saxton JM,Winter EM,Bianchi SM

    更新日期:2014-01-01 00:00:00

  • Sliding and lower limb mechanics during sit-stand-sit transitions with a standing wheelchair.

    abstract:PURPOSE:This study aimed to investigate the shear displacement between the body and backrest/seat, range of motion (ROM), and force acting on the lower limb joints during sit-stand-sit transitions by operating an electric-powered standing wheelchair. METHODS AND MATERIALS:The amounts of sliding along the backrest and ...

    journal_title:BioMed research international

    pub_type: 临床试验,杂志文章

    doi:10.1155/2014/236486

    authors: Yang YS,Chen MD,Fang WC,Chang JJ,Kuo CC

    更新日期:2014-01-01 00:00:00

  • Donor and Recipient Outcomes following Robotic-Assisted Laparoscopic Living Donor Nephrectomy: A Systematic Review.

    abstract:Aims:We aimed to summarize available lines of evidence about intraoperative and postoperative donor outcomes following robotic-assisted laparoscopic donor nephrectomy (RALDN) as well as outcomes of graft and recipients. Methods:A systematic review of PubMed/Medline, ISI Web of Knowledge, and Scopus databases was perfo...

    journal_title:BioMed research international

    pub_type: 杂志文章,meta分析

    doi:10.1155/2019/1729138

    authors: Creta M,Calogero A,Sagnelli C,Peluso G,Incollingo P,Candida M,Minieri G,Longo N,Fusco F,Tammaro V,Dodaro CA,Mangiapia F,Carlomagno N

    更新日期:2019-04-22 00:00:00

  • Impact of Moderate Heat, Carvacrol, and Thymol Treatments on the Viability, Injury, and Stress Response of Listeria monocytogenes.

    abstract::The microbial safety and stability of minimally processed foods are based on the application of combined preservative factors. Since microorganisms are able to develop adaptive networks to survive under conditions of stress, food safety may be affected, and therefore understanding of stress adaptive mechanisms plays a...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/548930

    authors: Guevara L,Antolinos V,Palop A,Periago PM

    更新日期:2015-01-01 00:00:00

  • Corrigendum to "Peripheral Blood Mononuclear Cells as a Laboratory to Study Dementia in the Elderly".

    abstract::[This corrects the article DOI: 10.1155/2014/169203.]. ...

    journal_title:BioMed research international

    pub_type: 已发布勘误

    doi:10.1155/2020/9175369

    authors: Arosio B,D'Addario C,Gussago C,Casati M,Tedone E,Ferri E,Nicolini P,Rossi PD,Maccarrone M,Mari D

    更新日期:2020-09-07 00:00:00

  • Potential Anticancer Mechanisms of a Novel EGFR/DNA-Targeting Combi-Molecule (JDF12) against DU145 Prostate Cancer Cells: An iTRAQ-Based Proteomic Analysis.

    abstract::The development of multitargeting drugs is an emerging trend in cancer research. To promote further development and clinical application of multitargeting drugs, this research was performed. MTT assay and flow cytometry of Annexin V/propidium iodide staining were used to confirm the proapoptotic efficacy of a novel co...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8050313

    authors: Zheng H,Liang G,Chen Y,Lin S,Liu W,Fang Y

    更新日期:2017-01-01 00:00:00

  • Early aging in Chernobyl clean-up workers: long-term study.

    abstract::This paper represents data of long-term open prospective study. 312 male clean-up workers, who participated in elimination of the Chernobyl disaster consequences in 1986-87, were observed and examined in Moscow Research Institute of Psychiatry. The average age of patients was 57,0 ± 6,8 years. All patients were diagno...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/948473

    authors: Krasnov V,Kryukov V,Samedova E,Emelianova I,Ryzhova I

    更新日期:2015-01-01 00:00:00

  • NLRP1 Overexpression Is Correlated with the Tumorigenesis and Proliferation of Human Breast Tumor.

    abstract::Recent studies suggest that nucleotide-binding domain leucine-rich repeat protein 1 (NLRP1) is a pivotal factor in the inflammatory process. However, the role of NLRP1 in breast cancer pathogenesis remains unclear. The aim of this study was to examine the expression and function of NLRP1 in breast cancer. We found tha...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/4938473

    authors: Wei Y,Huang H,Qiu Z,Li H,Tan J,Ren G,Wang X

    更新日期:2017-01-01 00:00:00

  • Contrast-Enhanced Mammography (CEM) for Detecting Residual Disease after Neoadjuvant Chemotherapy: A Comparison with Breast Magnetic Resonance Imaging (MRI).

    abstract:Objective:To evaluate the performance of contrast-enhanced mammography (CEM) compared to magnetic resonance imaging (MRI) for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in women with newly diagnosed breast cancer. Methods:The institutional review board approved this study. This prospective stu...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8531916

    authors: Barra FR,Sobrinho AB,Barra RR,Magalhães MT,Aguiar LR,de Albuquerque GFL,Costa RP,Farage L,Pratesi R

    更新日期:2018-11-08 00:00:00

  • Effects of Platelet-Rich Plasma on Proliferation, Viability, and Odontogenic Differentiation of Neural Crest Stem-Like Cells Derived from Human Dental Apical Papilla.

    abstract:Objective:This study is aimed at evaluating the effects of platelet-rich plasma (PRP) on proliferation, viability, and odontogenic differentiation of neural crest stem-like cells (NCSCs) derived from human dental apical papilla. Materials and Methods:Cells from apical papillae were obtained and then induced to form ne...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2020/4671989

    authors: Li J,Xiang L,Guan C,Yang X,Hu X,Zhang X,Zhang W

    更新日期:2020-05-09 00:00:00

  • Assessment of Influences of Stenoses in Right Carotid Artery on Left Carotid Artery Using Wall Stress Marker.

    abstract::Purpose. Atherosclerosis is a diseased condition of blood vessel. It causes partial blockage in lumen of vessel and affects hemodynamic of localized flowing blood. Complex geometries like region of bifurcation also affects hemodynamic to a larger extent. Complexity further increases in presence of stenoses at region o...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/2935195

    authors: Bit A,Ghagare D,Rizvanov AA,Chattopadhyay H

    更新日期:2017-01-01 00:00:00

  • Folate-Functionalized Mesoporous Hollow SnO2 Nanofibers as a Targeting Drug Carrier to Improve the Antitumor Effect of Paclitaxel for Liver Cancer Therapy.

    abstract::In this study, we prepared PTX-loaded mesoporous hollow SnO2 nanofibers conjugated with folic acid (SFNFP) for liver cancer therapy. According to SEM and TEM characterization, SFNF showed a mesoporous hollow structure. The average outer diameter was 200 nm, and the wall thickness was 50 nm. The DSC and XRD study showe...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/8526190

    authors: Lv H,Wu C,Liu X,Bai A,Cao Y,Shang W,Hu L,Liu Y

    更新日期:2018-11-25 00:00:00

  • Photocatalytical Antibacterial Activity of Mixed-Phase TiO2 Nanocomposite Thin Films against Aggregatibacter actinomycetemcomitans.

    abstract::Mixed-phase TiO2 nanocomposite thin films consisting of anatase and rutile prepared on commercially pure Ti sheets via the electrochemical anodization and annealing treatments were investigated in terms of their photocatalytic activity for antibacterial use around dental implants. The resulting films were characterize...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/705871

    authors: Yeniyol S,Mutlu I,He Z,Yüksel B,Boylan RJ,Ürgen M,Karabuda ZC,Basegmez C,Ricci JL

    更新日期:2015-01-01 00:00:00

  • Optimized periocular template selection for human recognition.

    abstract::A novel approach for selecting a rectangular template around periocular region optimally potential for human recognition is proposed. A comparatively larger template of periocular image than the optimal one can be slightly more potent for recognition, but the larger template heavily slows down the biometric system by ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2013/481431

    authors: Bakshi S,Sa PK,Majhi B

    更新日期:2013-01-01 00:00:00

  • Automatic epileptic seizure detection using scalp EEG and advanced artificial intelligence techniques.

    abstract::The epilepsies are a heterogeneous group of neurological disorders and syndromes characterised by recurrent, involuntary, paroxysmal seizure activity, which is often associated with a clinicoelectrical correlate on the electroencephalogram. The diagnosis of epilepsy is usually made by a neurologist but can be difficul...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/986736

    authors: Fergus P,Hignett D,Hussain A,Al-Jumeily D,Abdel-Aziz K

    更新日期:2015-01-01 00:00:00

  • Salivary Antioxidant Status in Patients with Oral Lichen Planus: Correlation with Clinical Signs and Evolution during Treatment with Chamaemelum nobile.

    abstract::Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease, which manifests as a succession of outbreaks. OLP was associated with salivary oxidative stress. Randomized, double blind, parallel-group study was performed. The sample consisted of 55 clinically and histopathologically diagnosed OLP patients. ...

    journal_title:BioMed research international

    pub_type: 杂志文章,随机对照试验

    doi:10.1155/2018/5187549

    authors: Tvarijonaviciute A,Aznar-Cayuela C,Rubio CP,Tecles F,Ceron JJ,López-Jornet P

    更新日期:2018-05-27 00:00:00

  • Exclusive Enteral Nutrition Induces Remission in Pediatric Crohn's Disease via Modulation of the Gut Microbiota.

    abstract::Exclusive enteral nutrition (EEN) has been proven to be effective and safe in treating pediatric Crohn's disease (CD). EEN induces pediatric CD remission possibly through three pathways: (1) direct anti-inflammatory effects, (2) improved epithelial barrier function, and (3) modulation of the gut microbiota. Recent stu...

    journal_title:BioMed research international

    pub_type: 杂志文章,评审

    doi:10.1155/2017/8102589

    authors: Gong D,Yu X,Wang L,Kong L,Gong X,Dong Q

    更新日期:2017-01-01 00:00:00

  • Reduced β2GPI Inhibiting Glomerular Mesangial Cells VEGF-NO Axis Uncoupling Induced by High Glucose.

    abstract::VEGF-NO axis uncoupling is an important pathogenesis for DN. Reduced β2GPI could play a part in VEGF signaling pathway and has a protective effect on diabetic vascular disease. This study investigates the effect of reduced β2GPI on glomerular mesangial cells VEGF-NO axis uncoupling induced by high glucose. Compared to...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2018/5484731

    authors: Saijun Z,Xin L,Jie W,Shumin X,Shuaihui L,Pei Y

    更新日期:2018-07-18 00:00:00

  • Environmental epidemiology of intestinal schistosomiasis in Uganda: population dynamics of biomphalaria (gastropoda: planorbidae) in Lake Albert and Lake Victoria with observations on natural infections with digenetic trematodes.

    abstract::This study documented the population dynamics of Biomphalaria and associated natural infections with digenetic trematodes, along the shores of Lake Albert and Lake Victoria, recording local physicochemical factors. Over a two-and-a-half-year study period with monthly sampling, physicochemical factors were measured at ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2015/717261

    authors: Rowel C,Fred B,Betson M,Sousa-Figueiredo JC,Kabatereine NB,Stothard JR

    更新日期:2015-01-01 00:00:00

  • Contribution of psychological factors in dropping out from chronic obstructive pulmonary disease rehabilitation programs.

    abstract::Significant positive effects, particularly on psychological state in patients who completed the follow-up pulmonary rehabilitation programs, are indicated by a large number of studies. Yet, a remarkable proportion of selected patients drop out from these programs. In this study, we investigated existing differences on...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2014/401326

    authors: Tselebis A,Kosmas E,Bratis D,Pachi A,Ilias I,Harikiopoulou M,Theodorakopoulou E,Velentzas K,Dumitru S,Moussas G,Siafakas N,Tzanakis N

    更新日期:2014-01-01 00:00:00

  • A Fatty Acids Mixture Reduces Anxiety-Like Behaviors in Infant Rats Mediated by GABAA Receptors.

    abstract::Fatty acids (C6-C18) found in human amniotic fluid, colostrum, and maternal milk reduce behavioral indicators of experimental anxiety in adult Wistar rats. Unknown, however, is whether the anxiolytic-like effects of fatty acids provide a natural mechanism against anxiety in young offspring. The present study assessed ...

    journal_title:BioMed research international

    pub_type: 杂志文章

    doi:10.1155/2017/8798546

    authors: Bernal-Morales B,Cueto-Escobedo J,Guillén-Ruiz G,Rodríguez-Landa JF,Contreras CM

    更新日期:2017-01-01 00:00:00