Mineral and Phytochemical Profiles and Antioxidant Activity of Herbal Material from Two Temperate Astragalus Species.

Abstract:

:Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole plants at two growth stages and in morphological fractions. We also investigated the capacity of the plant extracts to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and to chelate ferrous ions. Chemical composition and antioxidant properties depended on species, maturity, and plant part. Herbal material of A. glycyphyllos was richer in Fe, total phenolics, and flavonoids, whereas extracts of A. cicer showed a higher antioxidant activity. Young plants had more isoflavones, showed greater quenching of DPPH radicals, and exhibited better mineral profiles than flowering plants. Among plant parts, leaves were the most valuable plant material according to most characteristics investigated. Isoflavone concentration in flowers was lower than in leaves and stems. None of the Astragalus samples contained detectable amounts of the alkaloid swainsonine. The study demonstrates the potential of plant material from two Astragalus species as a valuable source of iron, phenolic substances including isoflavones, free-radical scavengers, and Fe2+ chelators for pharmaceutical use.

journal_name

Biomed Res Int

authors

Butkutė B,Dagilytė A,Benetis R,Padarauskas A,Cesevičienė J,Olšauskaitė V,Lemežienė N

doi

10.1155/2018/6318630

subject

Has Abstract

pub_date

2018-01-21 00:00:00

pages

6318630

eissn

2314-6133

issn

2314-6141

journal_volume

2018

pub_type

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