Abstract:
:Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole plants at two growth stages and in morphological fractions. We also investigated the capacity of the plant extracts to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and to chelate ferrous ions. Chemical composition and antioxidant properties depended on species, maturity, and plant part. Herbal material of A. glycyphyllos was richer in Fe, total phenolics, and flavonoids, whereas extracts of A. cicer showed a higher antioxidant activity. Young plants had more isoflavones, showed greater quenching of DPPH radicals, and exhibited better mineral profiles than flowering plants. Among plant parts, leaves were the most valuable plant material according to most characteristics investigated. Isoflavone concentration in flowers was lower than in leaves and stems. None of the Astragalus samples contained detectable amounts of the alkaloid swainsonine. The study demonstrates the potential of plant material from two Astragalus species as a valuable source of iron, phenolic substances including isoflavones, free-radical scavengers, and Fe2+ chelators for pharmaceutical use.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Butkutė B,Dagilytė A,Benetis R,Padarauskas A,Cesevičienė J,Olšauskaitė V,Lemežienė Ndoi
10.1155/2018/6318630subject
Has Abstractpub_date
2018-01-21 00:00:00pages
6318630eissn
2314-6133issn
2314-6141journal_volume
2018pub_type
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