Role of the adjacent stroma cells in prostate cancer development and progression: synergy between TGF-β and IGF signaling.

abstract：Objective:Epidemiological studies have shown a correlation between periodontal disease (PD) and age-related macular degeneration (AMD). However, the results have been inconsistent, and no relevant meta-analysis has been performed on this topic. Hence, we performed a meta-analysis to evaluate whether the two diseases ar...

journal_title：BioMed research international

authors： Lv X,Li W,Fang Z,Xue X,Pan C

更新日期：2020-09-28 00:00:00

abstract：:Cigarette smoke is highly toxic, and it can promote increased production of reactive species and inflammatory response and leads to liver diseases. Quercetin is a flavonoid that displays antioxidant and anti-inflammatory activities in liver diseases. This study aimed at evaluating the protective effects of quercetin o...

journal_title：BioMed research international

authors： Machado-Junior PA,Araújo NPS,Souza ABF,Castro TF,Oliveira M,Costa GP,Matos NA,Vieira PMA,Talvani A,Bezerra FS,Cangussú SD

更新日期：2020-11-15 00:00:00

abstract：Background:Fingertips are a common site for hand injuries. The ideal substitute for fingertip pulp is tissue that matches texturally with minimal donor site morbidity. We described anatomical findings from cadaveric studies and the reliability of the palmar ulnar artery perforator (PUAP) free flap techniques for the re...

journal_title：BioMed research international

authors： Pak CS,Jeon JI,Myung Y,Lee YK,Kim BJ,Jeong JH,Kim BK

更新日期：2018-05-09 00:00:00

abstract：:We test the hypothesis that ultrasound-targeted microbubble destruction (UTMD) technique increases the renoprotective effect of kidney-targeted transplantation of bone-marrow-derived mesenchymal stem cells (BM-MSCs) in diabetic nephropathy (DN) rats. Diabetes was induced by streptozotocin injection (60 mg/Kg, intraper...

journal_title：BioMed research international

authors： Zhang Y,Ye C,Wang G,Gao Y,Tan K,Zhuo Z,Liu Z,Xia H,Yang D,Li P

更新日期：2013-01-01 00:00:00

abstract：:Tissue regeneration has become a promising treatment for craniomaxillofacial bone defects such as alveolar clefts. This study sought to assess the efficacy of lateral ramus cortical plate with buccal fat pad derived mesenchymal stem cells (BFSCs) in treatment of human alveolar cleft defects. Ten patients with unilater...

journal_title：BioMed research international

authors： Khojasteh A,Kheiri L,Behnia H,Tehranchi A,Nazeman P,Nadjmi N,Soleimani M

更新日期：2017-01-01 00:00:00

abstract：:Giardia duodenalis, is often seen as an opportunistic pathogen and one of the major food and waterborne parasites. Some insights of Giardia infestation in a diarrhoea-prone population were investigated in the present study. Our primary goal was to understand the interaction of this parasite with other pathogens during...

journal_title：BioMed research international

authors： Mukherjee AK,Chowdhury P,Rajendran K,Nozaki T,Ganguly S

更新日期：2014-01-01 00:00:00

abstract：AIM:To investigate the role and mechanism of miR-15b in the proliferation and apoptosis of glioma. METHODS:The miR-15b mimics were transfected into human glioma cells to upregulate the miR-15b expression. Cyclin D1 was determined by both western blotting analysis and luciferase reporter assay. Methylthiazol tetrazoliu...

journal_title：BioMed research international

authors： Sun G,Shi L,Yan S,Wan Z,Jiang N,Fu L,Li M,Guo J

更新日期：2014-01-01 00:00:00

abstract：:Brain injury such as traumatic brain injury (TBI) and stroke is the major cause of long-term disabilities in many countries. The increasing rate of brain damaged victims and the heterogeneity of impairments decrease rehabilitation effectiveness and competence resulting in higher cost of rehabilitation treatment. On th...

journal_title：BioMed research international

authors： Shapi'i A,Mat Zin NA,Elaklouk AM

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the efficacy and safety of pulmonary rehabilitation (PR) for pneumoconiosis. We systematically searched PubMed, Embase, The Cochrane Library, Web of Science, SinoMed, CNKI, VIP databases and Wanfang Data from their inception to June 1, 2019. A systematic review and meta-analysis of randomized cont...

journal_title：BioMed research international

authors： Zhao H,Xie Y,Wang J,Li X,Li J

更新日期：2020-07-28 00:00:00

abstract：:We encapsulated tumor necrosis factor-α (TNF-α), a major proinflammatory cytokine, into cholesteryl pullulan (CHP) to prepare TNF/CHP nanoparticles. In this report, we describe the immune-enhancing capability of the nanoparticles to act as a vaccine adjuvant. TNF/CHP nanoparticles showed excellent storage stability an...

journal_title：BioMed research international

authors： Nagatomo D,Taniai M,Ariyasu H,Taniguchi M,Aga M,Ariyasu T,Ohta T,Fukuda S

更新日期：2015-01-01 00:00:00

abstract：:In this study, the authors have developed endoscopic fibre-optic pressure sensor to detect variceal pressure and presented the validation of in vivo and in vitro studies, because the HVPG requires catheterization of hepatic veins, which is invasive and inconvenient. Compared with HVPG, it is better to measure directly...

journal_title：BioMed research international

authors： Sun B,Kong DR,Li SW,Yu DF,Wang GJ,Yu FF,Wu Q,Xu JM

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Sarcopenia is the presence of low muscle mass and low muscle function. The aim of this study was to establish cutoffs for low muscle mass using three published methods and to compare the prevalence of sarcopenia in older Australians. METHODS:Gender specific cutoffs levels were identified for low muscle mass...

journal_title：BioMed research international

authors： Yu S,Appleton S,Adams R,Chapman I,Wittert G,Visvanathan T,Visvanathan R

更新日期：2014-01-01 00:00:00

abstract：:Heart failure is a major and costly problem in public health, which, in certain cases, may lead to death. The failing heart undergo a series of electrical and structural changes that provide the underlying basis for disturbances like arrhythmias. Computer models of coupled electrical and mechanical activities of the h...

journal_title：BioMed research international

authors： Rocha BM,Toledo EM,Barra LP,dos Santos RW

更新日期：2015-01-01 00:00:00

abstract：:Myricetin has been reported as a promising chemopreventive compound with multiple biofunctions. To evaluate its influence on gene expressions in genome-wide set and further investigate its anti-inflammatory property, the present study performed Gene Ontology and Ingenuity Pathway Analysis (IPA) to describe the basic g...

journal_title：BioMed research international

authors： Li T,Zhu J,Deng F,Wu W,Zheng Z,Lv C,Li Y,Xiang W,Lu X,Qin S

更新日期：2019-03-07 00:00:00

abstract：:Obesity or maternal overnutrition during pregnancy and lactation might have long-term consequences in offspring health. Fetal programming is characterized by adaptive responses to specific environmental conditions during early life stages. Programming alters gene expression through epigenetic modifications leading to ...

journal_title：BioMed research international

authors： Montalvo-Martínez L,Maldonado-Ruiz R,Cárdenas-Tueme M,Reséndez-Pérez D,Camacho A

更新日期：2018-06-20 00:00:00

abstract：:Two fullerene derivatives (fullerenes 1 and 2), bearing a hydrophilic chain on the pyrrolidinic nitrogen, were developed with the aim to deliver anticancer agents to solid tumors. These two compounds showed a significantly different behaviour on human neoplastic cell lines in vitro in respect to healthy leukocytes. In...

journal_title：BioMed research international

authors： Pacor S,Grillo A,Đorđević L,Zorzet S,Lucafò M,Da Ros T,Prato M,Sava G

更新日期：2015-01-01 00:00:00

abstract：Background/Aims:The molecular mechanism of dormancy initiation of cancer stem cells (CSCs) is not clear. This study was to explore the molecular mechanism by which CSCs switch from mitotic division to quiescence. Methods:MTT assays, flow cytometry, Western blotting, qRT-PCR, and immunofluorescence staining were used t...

journal_title：BioMed research international

authors： Zhang W,Ren Z,Jia L,Li X,Jia X,Han Y

更新日期：2019-08-25 00:00:00

abstract：OBJECTIVE:To evaluate HIV risk perception and its associated factors among Chinese MSM. METHODS:A cross-sectional study was conducted among MSM with an HIV negative or unknown status in Beijing, China, between 2011 and 2012. A questionnaire interview was conducted and a blood sample was collected for HIV and syphilis ...

journal_title：BioMed research international

authors： Fan W,Yin L,Qian HZ,Li D,Shao Y,Vermund SH,Ruan Y,Zhang Z

更新日期：2014-01-01 00:00:00

abstract：:Epigenetic changes have major role in the normal development and programming of gene expression. Aberrant methylation results in carcinogenesis. The primary objective of our study is to determine whether primary tumor tissue and cultured tumor cells in 2D and 3D tissue culture systems have the same methylation signatu...

journal_title：BioMed research international

authors： Şükrüoğlu Erdoğan Ö,Kılıç Erciyas S,Bilir A,Buğra Tunçer Ş,Akdeniz Ödemiş D,Kurul S,Karanlık H,Cabıoğlu N,Yazıcı H

更新日期：2019-01-17 00:00:00

abstract：:A new fungus Cladosporium oxysporum GQ-3 producing extracellular xylanase was isolated from decaying agricultural waste and identified based on the morphology and comparison of internal transcribed spacer (ITS) rDNA gene sequence. C. oxysporum produced maximum xylanase activity of 55.92 U/mL with wheat bran as a subst...

journal_title：BioMed research international

authors： Guan GQ,Zhao PX,Zhao J,Wang MJ,Huo SH,Cui FJ,Jiang JX

更新日期：2016-01-01 00:00:00

abstract：:Tomatoes and tomato based-foods contain beneficial microorganisms and various organic acids that have important nutritional values for human. The objective of this study was to access the physiochemical properties of fermented tomatoes juices and to evaluate the competitiveness of lactic acid bacteria (LAB) against Li...

journal_title：BioMed research international

authors： Bah A,Albano H,Barbosa JB,Fhoula I,Gharbi Y,Najjari A,Boudabous A,Teixeira P,Ouzari HI

更新日期：2019-02-26 00:00:00

abstract：:Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE-/-) AS mice, which were trained by WBV (15 Hz, 30 m...

journal_title：BioMed research international

authors： Wu H,Zhang Y,Yang X,Li X,Shao Z,Zhou Z,Li Y,Pan S,Liu C

更新日期：2018-03-07 00:00:00

abstract：:Increasing consumption of tobacco and alcohol has led to a steady increase in the incidence of head and neck cancers in Asia. The drawbacks associated with the existing chemotherapeutic and surgical interventions have necessitated the development of a safer alternative for therapy of head and neck cancers. In this stu...

journal_title：BioMed research international

authors： Mohan A,Narayanan S,Sethuraman S,Krishnan UM

更新日期：2014-01-01 00:00:00

abstract：:Astrocytic impairment is a pathologic feature of neuromyelitis optica spectrum disorder (NMOSD). S100B and glial fibrillary acidic protein (GFAP) are the two most commonly used astrocytic markers. The aim of this study was to evaluate whether CSF-S100B could serve as a marker of NMOSD. We enrolled 49 NMOSD patients [2...

journal_title：BioMed research international

authors： Wei Y,Chang H,Li X,Du L,Xu W,Cong H,Yao Y,Zhang X,Yin L

更新日期：2018-10-22 00:00:00

abstract：:Postprandial metabolic response depends on the meals' components and can be different in normal weight and obese people. However, there are some discrepancies between various reports. The aim of this study was to determine the metabolic response after intake of standardised meals with various fat and carbohydrate cont...

journal_title：BioMed research international

authors： Adamska E,Ostrowska L,Gościk J,Waszczeniuk M,Krętowski A,Górska M

更新日期：2015-01-01 00:00:00

abstract：:The use of endotamponade agents has gained a major role in the management of macular complications of high myopia. Myopic foveoschisis and macular hole are the main macular complication of pathologic myopia, this growing condition that is a main cause of visual loss, especially in patients at a younger age. We discuss...

journal_title：BioMed research international

authors： Valldeperas X,Lorenzo-Carrero J

更新日期：2014-01-01 00:00:00

abstract：Objectives:To evaluate the effects of pentobarbital dosages on lower urinary tract function and to define an appropriate dosage of sodium pentobarbital that would be suitable for urodynamic studies in which recovery from anesthesia and long term survive were needed for subsequent experiment. Methods:Twenty-four 8-week...

journal_title：BioMed research international

authors： Xu SF,Du GH,Abulikim K,Cao P,Tan HB

更新日期：2020-06-11 00:00:00

abstract：:Unipotent spermatogonial stem cells (SSCs) can be transformed into ESC-like cells that exhibit pluripotency in vitro. However, except for mouse models, their characterization and their origins have remained controversies in other models including humans. This controversy has arisen primarily from the lack of the direc...

journal_title：BioMed research international

authors： Lim JJ,Kim HJ,Kim KS,Hong JY,Lee DR

更新日期：2013-01-01 00:00:00

abstract：:New and innovative treatment strategies for cancer patients in the fields of immunotherapy and radiotherapy are rapidly developing in parallel. Among the most promising preclinical treatment approaches is combining immunotherapy with radiotherapy where early data suggest synergistic effects in several tumor model syst...

journal_title：BioMed research international

authors： Zeng J,Harris TJ,Lim M,Drake CG,Tran PT

更新日期：2013-01-01 00:00:00

abstract：:The aim of this study was to determine the capacity of biofilm formation of atypical enteropathogenic Escherichia coli (aEPEC) strains on abiotic and biotic surfaces. Ninety-one aEPEC strains, isolated from feces of children with diarrhea, were analyzed by the crystal violet (CV) assay on an abiotic surface after 24 h...

journal_title：BioMed research international

authors： Culler HF,Mota CM,Abe CM,Elias WP,Sircili MP,Franzolin MR

更新日期：2014-01-01 00:00:00