Elevated Preoperative Serum CA125 Predicts Larger Tumor Diameter in Patients with Hepatocellular Carcinoma and Low AFP Levels.

abstract：:Secretory leukoprotease inhibitor (SLPI) is an anti-inflammatory protein present in respiratory secretions. Whilst epithelial cell SLPI is extensively studied, neutrophil associated SLPI is poorly characterised. Neutrophil function including chemotaxis and degranulation of proteolytic enzymes involves changes in cytos...

journal_title：BioMed research international

authors： Reeves EP,Banville N,Ryan DM,O'Reilly N,Bergin DA,Pohl K,Molloy K,McElvaney OJ,Alsaleh K,Aljorfi A,Kandalaft O,O'Flynn E,Geraghty P,O'Neill SJ,McElvaney NG

更新日期：2013-01-01 00:00:00

abstract：:Among uterine structural abnormalities, myomas and adenomyosis represent two distinct, though frequently coexistent entities, with a remarkable prevalence in women of reproductive age. Various mechanisms have been proposed to explain the impact of each of them on reproductive outcome. In respect to myomas, current evi...

journal_title：BioMed research international

authors： Vlahos NF,Theodoridis TD,Partsinevelos GA

更新日期：2017-01-01 00:00:00

abstract：Background:Circular RNA (circRNA) is a noncoding RNA that forms a closed-loop structure, and its abnormal expression may cause disease. We aimed to find potential network for circRNA-related competitive endogenous RNA (ceRNA) in atrial fibrillation (AF). Methods:The circRNA, miRNA, and mRNA expression profiles in the ...

journal_title：BioMed research international

authors： Liu T,Zhang G,Wang Y,Rao M,Zhang Y,Guo A,Wang M

更新日期：2020-09-29 00:00:00

abstract：:The microbial resistance of fungi and bacteria is currently considered a major public health problem. Esters derived from cinnamic acid have a broad spectrum of pharmacological properties that include antimicrobial activity. In this study, a collection of structurally related 4-chlorocinnamic acid esters was prepared ...

journal_title：BioMed research international

authors： Silva RHN,Andrade ACM,Nóbrega DF,de Castro RD,Pessôa HLF,Rani N,de Sousa DP

更新日期：2019-04-23 00:00:00

abstract：:Two field isolates of Rhizoctonia solani were isolated from infected paddy plants in Malaysia. These isolates were verified via ITS-rDNA analysis that yielded ~720 bp products of the ITS1-5.8S-ITS4 region, respectively. The sequenced products showed insertion and substitution incidences which may result in strain dive...

journal_title：BioMed research international

authors： Nadarajah K,Omar NS,Rosli MM,Shin Tze O

更新日期：2014-01-01 00:00:00

abstract：Background:In peritoneal dialysis (PD) patients, whether angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) could protect residual renal function is still controversial. To assess the effects of ACEIs and ARBs on the residual renal function and cardiovascular (CV) events in perito...

journal_title：BioMed research international

authors： Ding L,Yang J,Li L,Yang Y

更新日期：2020-09-23 00:00:00

abstract：:Mutations in the kinase domain of epidermal growth factor receptor (EGFR) have high levels of basal receptor phosphorylation and are associated with clinical responsiveness to Iressa in patients with nonsmall cell lung cancer (NSCLC). This study aimed to assess the feasibility of morpholino-[(124)I]IPQA derivative as ...

journal_title：BioMed research international

authors： Yeh SH,Lin CF,Kong FL,Wang HE,Hsieh YJ,Gelovani JG,Liu RS

更新日期：2013-01-01 00:00:00

abstract：:In our study, we evaluated the feasibility of a new sampling method for splenic stiffness (SS) measurement by Quantitative Acoustic Radiation Force Impulse Elastography (Virtual Touch Tissue Quantification (VTTQ)).We measured SS in 54 patients with HCV-related cirrhosis of whom 28 with esophageal varices (EV), 27 with...

journal_title：BioMed research international

authors： Rizzo L,Attanasio M,Pinzone MR,Berretta M,Malaguarnera M,Morra A,L'Abbate L,Balestreri L,Nunnari G,Cacopardo B

更新日期：2014-01-01 00:00:00

abstract：:A bioenergetical analysis of swimming at intensities near competitive distances is inexistent. It was aimed to compare the transient VO2 kinetics responses and metabolic contributions whilst swimming at different velocities around VO2max. 12 trained male swimmers performed (i) an incremental protocol to determine the ...

journal_title：BioMed research international

authors： Sousa AC,Vilas-Boas JP,Fernandes RJ

更新日期：2014-01-01 00:00:00

abstract：:Stimuli responsive pH- and temperature-sensitive hydrogel drug delivery systems, as those based on N-isopropylacrylamide (NiPAAm) and itaconic acid (IA), have been attracting much of the attention of the scientific community nowadays, especially in the field of drug release. By adjusting comonomer composition, the mat...

journal_title：BioMed research international

authors： Milašinović N,Knežević-Jugović Z,Milosavljević N,Lučić Škorić M,Filipović J,Kalagasidis Krušić M

更新日期：2014-01-01 00:00:00

abstract：:Models using large animals that are suitable for studying artificial liver support system (ALSS) are urgently needed. Presently available acute liver failure (ALF) models mainly involve pigs or dogs. Establishment of current surgical ALF models (hepatectomy/devascularization) requires either very good surgical skills ...

journal_title：BioMed research international

authors： Cai L,Weng J,Feng L,He G,Qin J,Zhang Z,Li Y,Peng Q,Jiang Z,Pan M,Gao Y

更新日期：2016-01-01 00:00:00

abstract：:Lung cancer is the leading cause of cancer-related death worldwide, and the most common histologic subtype is lung adenocarcinoma (LUAD). Due to the significant mortality and morbidity rates among patients with LUAD, the identification of novel biomarkers to guide diagnosis, prognosis, and therapy is urgent. Guanosine...

journal_title：BioMed research international

authors： Zhang Z,Wang J,Mao J,Li F,Chen W,Wang W

更新日期：2020-10-19 00:00:00

abstract：Background:There is little data available on HBV infection and mother-to-child transmission (MTCT) in Vietnam. Objective:This study is aimed at assessing the prevalence of HBV infection and the current situation of MTCT in Haiphong, Vietnam. Methods:A transversal survey of 1721 pregnant women followed by an observati...

journal_title：BioMed research international

authors： Khue PM,Thuy Linh NT,Vinh VH,Dung LV,Nguyen Van B

更新日期：2020-08-20 00:00:00

abstract：:Parkinson's disease (PD) is a major neurodegenerative disorder for which the etiology and pathogenesis remain as elusive as for Alzheimer's disease. PD appears to be caused by genetic and environmental factors, and pedigree and cohort studies have identified numerous susceptibility genes and loci related to PD. Autoso...

journal_title：BioMed research international

authors： Yang X,Xu Y

更新日期：2014-01-01 00:00:00

abstract：Objective of Study:To investigate, using the FEM, the influence of different notching angles on a zirconium dioxide coping with the aim of establishing the optimal connection conditions with veneering ceramic. Materials and Methods:To calculate the stresses in the connection between zirconia coping and veneering ceram...

journal_title：BioMed research international

authors： Śmielak B,Klimek L,Świniarski J

更新日期：2019-07-01 00:00:00

abstract：:Periodontitis is an inflammatory disease involving complex interactions between oral microorganisms and the host immune response. Understanding the structure of the microbiota community associated with periodontitis is essential for improving classifications and diagnoses of various types of periodontal diseases and w...

journal_title：BioMed research international

authors： Chen WP,Chang SH,Tang CY,Liou ML,Tsai SJ,Lin YL

更新日期：2018-11-15 00:00:00

abstract：:Chagas disease is caused by Trypanosoma cruzi infection. Besides the host-related factors, such as immune response and genetic background, the parasite, strain, and occurrences of reinfection episodes, may influence disease outcome. Our results demonstrate that both the primary infection and the reinfection with the C...

journal_title：BioMed research international

authors： Reis Machado J,Silva MV,Borges DC,da Silva CA,Ramirez LE,dos Reis MA,Castellano LR,Rodrigues V,Rodrigues DB

更新日期：2014-01-01 00:00:00

abstract：:Reactive oxygen species (ROS) damage macromolecules and cellular components in nearly all kinds of cells and often generate toxic intracellular byproducts. In this work, aldehyde generation derived from the Escherichia coli membrane oxidation as well as membrane fatty acid profiles, protein oxidation, and bacterial re...

journal_title：BioMed research international

authors： Pradenas GA,Díaz-Vásquez WA,Pérez-Donoso JM,Vásquez CC

更新日期：2013-01-01 00:00:00

abstract：:Introduction. Luteolin, a falconoid compound in many Chinese herbs and formula, plays important roles in cardiovascular diseases. The underlying mechanism of luteolin remains to be further elaborated. Methods. A model of hydrogen peroxide- (H2O2-) induced H9C2 cells apoptosis was established. Cell viabilities were exa...

journal_title：BioMed research international

authors： Chang H,Li C,Huo K,Wang Q,Lu L,Zhang Q,Wang Y,Wang W

更新日期：2016-01-01 00:00:00

abstract：:Hypoxia plays an essential role in orchestrating Epithelial-mesenchymal transition and promoting metastasis of colorectal cancer. However, the underlying mechanisms are still not well elucidated. Here, we present that hypoxic exposure causes endoplasmic reticulum stress and activates the unfolded protein response path...

journal_title：BioMed research international

authors： Zheng H,Wu Y,Guo T,Liu F,Xu Y,Cai S

更新日期：2020-01-27 00:00:00

abstract：:This study shows that membrane-associated cytoskeletal protein structures and the erythrocyte morphology undergo profound changes during hypoxia. Hypoxia also intensified oxidative processes in the lipid phase of the bilayer of red blood cell membranes. Sodium nitroprusside impaired the morphology of red blood cells a...

journal_title：BioMed research international

authors： Revin VV,Gromova NV,Revina ES,Prosnikova KV,Revina NV,Bochkareva SS,Stepushkina OG,Grunyushkin IP,Tairova MR,Incina VI

更新日期：2019-12-07 00:00:00

abstract：:Adverse drug reactions (ADRs) are responsible for drug candidate failure during clinical trials. It is crucial to investigate biological pathways contributing to ADRs. Here, we applied a large-scale analysis to identify overrepresented ADR-pathway combinations through merging clinical phenotypic data, biological pathw...

journal_title：BioMed research international

authors： Chen X,Wang Y,Wang P,Lian B,Li C,Wang J,Li X,Jiang W

更新日期：2015-01-01 00:00:00

abstract：:Aims. To compare the clinical features of endometrial polyps (EPs) between patients with endometriosis (EM) (EM group) and without EM (non-EM group). Methods and Results. Seventy-six cases in the EM group and 133 cases in the non-EM group underwent laparotomy or hysteroscopy and laparoscopy; later, it was confirmed th...

journal_title：BioMed research international

authors： Wang N,Zhang Y,Liu B

更新日期：2016-01-01 00:00:00

abstract：Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

journal_title：BioMed research international

authors： Liu H,Zhang Y,Sun S,Wang S

更新日期：2019-07-17 00:00:00

abstract：:Apc-mutated Pirc rats, spontaneously developing intestinal tumours, are resistant to 1,2-dimethylhydrazine- (DMH-) induced colon apoptosis. To understand this phenomenon, we analyzed the expression of genotoxic stress-related genes Mgmt, Gsta1, and Gstp1 in the colon of wt and Pirc rats in basal conditions and 24 h af...

journal_title：BioMed research international

authors： Femia AP,Luceri C,Lodovici M,Crucitta S,Caderni G

更新日期：2016-01-01 00:00:00

abstract：:In this study, we prepared PTX-loaded mesoporous hollow SnO2 nanofibers conjugated with folic acid (SFNFP) for liver cancer therapy. According to SEM and TEM characterization, SFNF showed a mesoporous hollow structure. The average outer diameter was 200 nm, and the wall thickness was 50 nm. The DSC and XRD study showe...

journal_title：BioMed research international

authors： Lv H,Wu C,Liu X,Bai A,Cao Y,Shang W,Hu L,Liu Y

更新日期：2018-11-25 00:00:00

abstract：:Despite the rapid progression of cancer pharmacotherapy, the high drug resistance of pancreatic ductal adenocarcinoma (PDA) makes it one of the most lethal malignancies. Therefore, there are high expectations associated with experimental therapies, such as electrochemotherapy (ECT). This technique involves the applica...

journal_title：BioMed research international

authors： Michel O,Kulbacka J,Saczko J,Mączyńska J,Błasiak P,Rossowska J,Rzechonek A

更新日期：2018-03-19 00:00:00

abstract：:ELMO3 is a member of the engulfment and cell motility (ELMO) protein family, which plays a vital role in the process of chemotaxis and metastasis of tumor cells. However, remarkably little is known about the role of ELMO3 in cancer. The present study was conducted to investigate the function and role of ELMO3 in gastr...

journal_title：BioMed research international

authors： Hu Y,Yu Q,Zhong Y,Shen W,Zhou X,Liu X,Xu M,Zhou N,Min W,Gao D

更新日期：2018-09-24 00:00:00

abstract：:We compared the efficacy of intravitreal aflibercept (IVA) to intravitreal ranibizumab (IVR) injections in eyes with diabetic macular edema (DME). The medical records of 49 eyes of 36 patients who were diagnosed with DME and had received IVR and 46 eyes of 40 patients who had received IVA treatment were reviewed. The ...

journal_title：BioMed research international

authors： Shimizu N,Oshitari T,Tatsumi T,Takatsuna Y,Arai M,Sato E,Baba T,Yamamoto S

更新日期：2017-01-01 00:00:00

abstract：:We developed a new product called titanium-prepared platelet-rich fibrin (T-PRF). The T-PRF method is based on the hypothesis that titanium may be more effective in activating platelets than the silica activators used with glass tubes in Chouckroun's leukocyte- and platelet-rich fibrin (L-PRF) method. In this study, w...

journal_title：BioMed research international

authors： Tunalı M,Özdemir H,Küçükodacı Z,Akman S,Yaprak E,Toker H,Fıratlı E

更新日期：2014-01-01 00:00:00