Effect and Mechanism of Survivin on Hypoxia-Induced Multidrug Resistance of Human Laryngeal Carcinoma Cells.

abstract：:Little is known about how prenatal maternal stress (PNMS) influences risks of asthma in humans. In this small study, we sought to determine whether disaster-related PNMS would predict asthma risk in children. In June 1998, we assessed severity of objective hardship and subjective distress in women pregnant during the ...

journal_title：BioMed research international

authors： Turcotte-Tremblay AM,Lim R,Laplante DP,Kobzik L,Brunet A,King S

更新日期：2014-01-01 00:00:00

abstract：Background:We investigated the potential safety of remimazolam and propofol in malignant hyperthermia- (HM-) susceptible patients using ryanodine receptor 1- (RYR1-) expressing human embryonic kidney- (HEK-) 293 cells. Methods:We compared the enhanced responsiveness of HEK-293 cells expressing wild-type RYR1 with that...

journal_title：BioMed research international

authors： Watanabe T,Miyoshi H,Noda Y,Narasaki S,Morio A,Toyota Y,Kimura H,Mukaida K,Yasuda T,Tsutsumi YM

更新日期：2021-01-04 00:00:00

abstract：:Glioblastoma (GBM) is the most common and malignant intracranial tumor in adults. Despite continuous improvements in diagnosis and therapeutic method, the prognosis is still far away from expectations. The invasive phenotype of GBM is the main reason for the poor prognosis. Epithelial-mesenchymal transition (EMT) is r...

journal_title：BioMed research international

authors： Song Y,Chen Y,Li Y,Lyu X,Cui J,Cheng Y,Zheng T,Zhao L,Zhao G

更新日期：2019-04-17 00:00:00

abstract：BACKGROUND AND AIM:Trace elements and vitamins play a vital role in human body to perform its function properly. Thalassemic patients are at risk of micronutrient deficiency. This study estimated levels of vitamins A, C, E, B12, folic acid, total homocysteine (tHcy), and methylmalonic acid (MMA) along with trace elemen...

journal_title：BioMed research international

authors： Sherief LM,Abd El-Salam SM,Kamal NM,El Safy O,Almalky MA,Azab SF,Morsy HM,Gharieb AF

更新日期：2014-01-01 00:00:00

abstract：:External focus of attention (EFA) and internal focus of attention (IFA) represent commonly used strategies to instruct subjects during exercise. Several studies showed EFA to be more effective than IFA to improve motor performance and learning. To date the role of these strategies on motor performance during finger mo...

journal_title：BioMed research international

authors： Rossettini G,Testa M,Vicentini M,Manganotti P

更新日期：2017-01-01 00:00:00

abstract：:Lipases are water-soluble enzymes that act on insoluble substrates and catalyze the hydrolysis of long-chain triglycerides. Lipases play a vital role in the food, detergent, chemical, and pharmaceutical industries. In the past, fungal lipases gained significant attention in the industries due to their substrate specif...

journal_title：BioMed research international

authors： Gopinath SC,Anbu P,Lakshmipriya T,Hilda A

更新日期：2013-01-01 00:00:00

abstract：:Cystic change in metastatic lymph nodes of papillary thyroid carcinoma (PTC) is a diagnostic challenge for fine needle aspiration (FNA) because of the scant cellularity. The aim of this study was to evaluate the measurement of thyroglobulin in fine needle aspirate (Tg-FNA) for detecting metastatic PTC in patients with...

journal_title：BioMed research international

authors： Wang Y,Zhao H,Wang YX,Wang MJ,Zhang ZH,Zhang L,Zhang B,Ahuja AT,Zhou CW,Jiang YX,Guo HQ

更新日期：2016-01-01 00:00:00

abstract：:Study of the probiotic potential of microorganisms isolated from fermented foods has been increasing, especially studies related to lactobacilli. In intestinal models, lactobacilli have demonstrated beneficial properties, such as anti-inflammatory activity and increased antibody production, but the molecular mechanism...

journal_title：BioMed research international

authors： Pessoa WFB,Melgaço ACC,de Almeida ME,Ramos LP,Rezende RP,Romano CC

更新日期：2017-01-01 00:00:00

abstract：Introduction:To identify and analyze factors that influence administration, recognition, and compliance of medicine among community residents in Jilin Province, China. Methods:A survey was carried out among 2417 community residents in Jilin Province, China, to study their administration (CRA), recognition (CRR), and c...

journal_title：BioMed research international

authors： Song YQ,Zhang WR,Zhang SX,Wang TH,Jiang Z,Meng CF,Zhang TZ,Xin QZ,Cao KJ,Zhang Y,Sun Y

更新日期：2020-07-18 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：:The use of endotamponade agents has gained a major role in the management of macular complications of high myopia. Myopic foveoschisis and macular hole are the main macular complication of pathologic myopia, this growing condition that is a main cause of visual loss, especially in patients at a younger age. We discuss...

journal_title：BioMed research international

authors： Valldeperas X,Lorenzo-Carrero J

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Conventional surgical techniques of laryngomicrosurgery (LMS) on hemorrhagic vocal polyps are often difficult due to obscuration of the surgical field by inadvertent bleeding from the lesion, and there are often significant amounts of mucosal epithelium loss. Here, we introduce our surgical technique using pu...

journal_title：BioMed research international

authors： Byeon HK,Han JH,Choi BI,Hwang HJ,Kim JH,Choi HS

更新日期：2015-01-01 00:00:00

abstract：:Three-dimensional (3D) liver tumor segmentation from Computed Tomography (CT) images is a prerequisite for computer-aided diagnosis, treatment planning, and monitoring of liver cancer. Despite many years of research, 3D liver tumor segmentation remains a challenging task. In this paper, an efficient semiautomatic meth...

journal_title：BioMed research international

authors： Wu W,Wu S,Zhou Z,Zhang R,Zhang Y

更新日期：2017-01-01 00:00:00

abstract：:Blocking glioma cell invasion has been challenging due to cancer cells that can swiftly switch their migration mode, and agents that can block more than one migration mode are sought after. We found that small molecule 2-(1H-indole-3-carbonyl)-thiazole-4-carboxylic acid methyl ester (ITE), an endogenous aryl hydrocarb...

journal_title：BioMed research international

authors： Zhao L,Shu Q,Sun H,Ma Y,Kang D,Zhao Y,Lu J,Gong P,Yang F,Wan F

更新日期：2020-10-03 00:00:00

abstract：BACKGROUND:The genome-wide association studies (GWAS) have been successful during the last few years. A key challenge is that the interpretation of the results is not straightforward, especially for transacting SNPs. Integration of transcriptome data into GWAS may provide clues elucidating the mechanisms by which a gen...

journal_title：BioMed research international

authors： Jiang G,Chakraborty A,Wang Z,Boustani M,Liu Y,Skaar T,Li L

更新日期：2013-01-01 00:00:00

abstract：:The proper methylation status of histones is essential for appropriate cell lineage and organogenesis. EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development. The pig is an increasing important animal model for molecular study and pharmaceutical research. Ho...

journal_title：BioMed research international

authors： Tan B,Hong L,Qiao J,Zhou J,Xing P,Yan G,Zheng E,Cai G,Huang S,Wu Z,Gu T

更新日期：2020-10-05 00:00:00

abstract：:Trichoderma spp. are important biocontrol filamentous fungi and have tremendous potential in soil bioremediation. In our previous studies, a C2H2 type transcription factor coding gene (thmea1) was cloned from a biocontrol agent T. harzianum Th-33; the encoded sequence of thmea1 contained 3 conserved C2H2 domains with ...

journal_title：BioMed research international

authors： Mei J,Wang L,Jiang X,Wu B,Li M

更新日期：2018-07-18 00:00:00

abstract：:Background. There has been a decline in emphasis of the value of physical examination in heart failure (HF) with increased reliance on cardiac imaging. We aim to study the clinical and prognostic significance of positive hepatojugular reflux (HJR) on discharge in patients hospitalized with HF. Methods. Using the ESCAP...

journal_title：BioMed research international

authors： Omar HR,Guglin M

更新日期：2017-01-01 00:00:00

abstract：Aims:We aimed to summarize available lines of evidence about intraoperative and postoperative donor outcomes following robotic-assisted laparoscopic donor nephrectomy (RALDN) as well as outcomes of graft and recipients. Methods:A systematic review of PubMed/Medline, ISI Web of Knowledge, and Scopus databases was perfo...

journal_title：BioMed research international

authors： Creta M,Calogero A,Sagnelli C,Peluso G,Incollingo P,Candida M,Minieri G,Longo N,Fusco F,Tammaro V,Dodaro CA,Mangiapia F,Carlomagno N

更新日期：2019-04-22 00:00:00

abstract：:Polyphenolic compounds are plant nutraceuticals showing a huge structural diversity, including chlorogenic acids, hydrolyzable tannins, and flavonoids (flavonols, flavanones, flavan-3-ols, anthocyanidins, isoflavones, and flavones). Most of them occur as glycosylated derivatives in plants and foods. In order to become...

journal_title：BioMed research international

authors： Marín L,Miguélez EM,Villar CJ,Lombó F

更新日期：2015-01-01 00:00:00

abstract：:This study aims to ascertain whether cytokines in the aqueous humor can predict macular edema (ME) in diabetic patients following uncomplicated phacoemulsification cataract surgery. Undiluted aqueous humor samples were obtained from 136 consecutive type 2 diabetic patients who underwent cataract surgery. The concentra...

journal_title：BioMed research international

authors： Dong N,Xu B,Wang B,Chu L,Tang X

更新日期：2015-01-01 00:00:00

abstract：:The establishment of the subgingival microbiota is dependent on successive colonization of the implant surface by bacterial species. Different implant surface topographies could influence the bacterial adsorption and therefore jeopardize the implant survival. This study evaluated the biofilm formation capacity of five...

journal_title：BioMed research international

authors： Pita PP,Rodrigues JA,Ota-Tsuzuki C,Miato TF,Zenobio EG,Giro G,Figueiredo LC,Gonçalves C,Gehrke SA,Cassoni A,Shibli JA

更新日期：2015-01-01 00:00:00

abstract：:The present study is designed to determine potential target genes involved in hepatocellular carcinoma (HCC) and provide possible underlying mechanisms of action. Several studies (GSE112790, GSE87630, and GSE56140) from the GEO database looking at molecular characteristics in HCC were screened and analyzed by GEO2R, w...

journal_title：BioMed research international

authors： Mu D,Qin F,Li B,Zhou Q

更新日期：2020-10-05 00:00:00

abstract：Background:Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by sacroiliitis and spinal rigidity of the axial joints. The role of oxidative stress and increased proinflammatory cytokines is well documented in AS pathogenesis. Punicalagin (2,3-hexahydroxydiphenoyl-gallagyl-D-glucose), an ellagi...

journal_title：BioMed research international

authors： Feng X,Yang Q,Wang C,Tong W,Xu W

更新日期：2020-09-23 00:00:00

abstract：:Objective. This study aims to extract motor ingredients through data mining from wearable sensors in a virtual reality goal-directed shoulder rehabilitation (GDSR) system and to examine their effects toward clinical assessment. Design. A single-group before/after comparison. Setting. Outpatient research hospital. Subj...

journal_title：BioMed research international

authors： Lee SH,Yeh SC,Chan RC,Chen S,Yang G,Zheng LR

更新日期：2016-01-01 00:00:00

abstract：:Although extensive studies have identified large number of microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) in ischemic stroke, the RNA regulation network response to focal ischemia remains poorly understood. In this study, we simultaneously interrogate the expression profiles of lncRNAs, miRNAs, and mRNAs changes...

journal_title：BioMed research international

authors： Liu J,Zhang KS,Hu B,Li SG,Li Q,Luo YP,Wang Y,Deng ZF

更新日期：2018-01-08 00:00:00

abstract：Objectives:Childhood malnutrition is major health concern in many low- and middle-income countries, including Vietnam. It was a major risk factor for child mortality and adult ill-health. Malnutrition could increase the risk of serious infections; conversely current diseases also had a negative impact on the growth of ...

journal_title：BioMed research international

authors： Huynh G,Huynh QHN,Nguyen NHT,Do QT,Khanh Tran V

更新日期：2019-02-05 00:00:00

abstract：:Hypertrophic Scars (HTSs) are a complex fibroproliferative disorder, and their exact mechanism is still not fully understood. In this study, we first found that cystic fibrosis transmembrane conductance regulator (CFTR) expression was downregulated in human hypertrophic scars at the RNA and protein levels by microarra...

journal_title：BioMed research international

authors： Zhou Y,Zhao Y,Du H,Suo Y,Chen H,Li H,Liang X,Li Q,Huang X

更新日期：2020-01-02 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a lethal malignancy with poor prognosis and limited treatment options. Transarterial chemoembolization (TACE) using chemotherapy agents-doxorubicin and cisplatin-is an accepted treatment option for locally advanced hepatocellular carcinoma. In the current study, we analyzed the expres...

journal_title：BioMed research international

authors： El-Halawany MS,Ismail HM,Zeeneldin AA,Elfiky A,Tantawy M,Kobaisi MH,Hamed I,Abdel Wahab AH

更新日期：2015-01-01 00:00:00

abstract：:Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

journal_title：BioMed research international

authors： Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

更新日期：2020-08-26 00:00:00