Systematic Analysis of RNA Regulatory Network in Rat Brain after Ischemic Stroke.

abstract：:Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-...

journal_title：BioMed research international

authors： Xu L,Sun Z,Fan Z

更新日期：2015-01-01 00:00:00

abstract：Objective:To explore the ability of asiatic acid to interfere with the invasion and proliferation of breast cancer cells by inhibiting WAVE3 expression and activation through the PI3K/AKT signaling pathway. Methods:The MDA-MB-231 cells with strong invasiveness were screened by transwell assay, and plasmids with high e...

journal_title：BioMed research international

authors： Gou XJ,Bai HH,Liu LW,Chen HY,Shi Q,Chang LS,Ding MM,Shi Q,Zhou MX,Chen WL,Zhang LM

更新日期：2020-02-10 00:00:00

abstract：:We aimed to predict the ten-year cardiovascular disease (CVD) risk among low-income urban dwellers of metropolitan Malaysia. Participants were selected from a cross-sectional survey conducted in Kuala Lumpur. To assess the 10-year CVD risk, we employed the Framingham risk scoring (FRS) models. Significant determinants...

journal_title：BioMed research international

authors： Su TT,Amiri M,Mohd Hairi F,Thangiah N,Bulgiba A,Majid HA

更新日期：2015-01-01 00:00:00

abstract：Purpose:To evaluate the relationships between objectively measured physical activity and physical fitness among preschool children. Methods:A total of 346 participants (201 boys and 145 girls) aged 3.5-5.5 years (M = 4.5 yr, SD = 0.47) from Shanghai, China, completed physical fitness assessments, including triceps ski...

journal_title：BioMed research international

authors： Fang H,Quan M,Zhou T,Sun S,Zhang J,Zhang H,Cao Z,Zhao G,Wang R,Chen P

更新日期：2017-01-01 00:00:00

abstract：:Application of enzymes in biotechnological process has expanded considerably in recent years. In food and related industry, major importance was being attached to the use of enzymes in upgrading quality, increasing yields of extractive processes, product stabilization, and improvement of flavor and byproduct utilizati...

journal_title：BioMed research international

authors： Oumer OJ,Abate D

更新日期：2018-04-03 00:00:00

abstract：:The zebrafish constitutes a powerful model organism with unique advantages for investigating the vertebrate circadian timing system and its regulation by light. In particular, the remarkably early and rapid development of the zebrafish circadian system has facilitated exploring the factors that control the onset of ci...

journal_title：BioMed research international

authors： Ben-Moshe Z,Foulkes NS,Gothilf Y

更新日期：2014-01-01 00:00:00

abstract：:TAL effectors (TALEs) contain a modular DNA-binding domain that is composed of tandem repeats. In all naturally occurring TALEs, the end of tandem repeats is invariantly a truncated half repeat. To investigate the potential role of the last half repeat in TALEs, we performed comparative molecular dynamics simulations ...

journal_title：BioMed research international

authors： Wan H,Chang S,Hu JP,Tian XH,Wang MH

更新日期：2016-01-01 00:00:00

abstract：:In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein is an attractive target for development of new blood coagulation inhibitors. Factor Xa is more effective and convenient target for creation of anticoagulants tha...

journal_title：BioMed research international

authors： Sulimov VB,Gribkova IV,Kochugaeva MP,Katkova EV,Sulimov AV,Kutov DC,Shikhaliev KS,Medvedeva SM,Krysin MY,Sinauridze EI,Ataullakhanov FI

更新日期：2015-01-01 00:00:00

abstract：:Despite being identified as a high risk cohort for psychosis, there has been relatively little research on the clinical presentation and assessment of Schizotypal Personality Disorder (SPD) in childhood. The current study aimed to develop a measure of childhood SPD (Melbourne Assessment of Schizotypy in Kids (MASK)) a...

journal_title：BioMed research international

authors： Jones HP,Testa RR,Ross N,Seal ML,Pantelis C,Tonge B

更新日期：2015-01-01 00:00:00

abstract：:Tumourigenesis is a mutation accumulation process, which is likely to start with a mutated founder cell. The evolutionary nature of tumor development makes phylogenetic models suitable for inferring tumor evolution through genetic variation data. Copy number variation (CNV) is the major genetic marker of the genome wi...

journal_title：BioMed research international

authors： Liang Y,Liao B,Zhu W

更新日期：2017-01-01 00:00:00

abstract：:The framework of graph theory provides useful tools for investigating the neural substrates of neuropsychiatric disorders. Graph description measures may be useful as predictor variables in classification procedures. Here, we consider several centrality measures as predictor features in a classification algorithm to i...

journal_title：BioMed research international

authors： dos Santos Siqueira A,Biazoli Junior CE,Comfort WE,Rohde LA,Sato JR

更新日期：2014-01-01 00:00:00

abstract：:Toxoplasma gondii (T. gondii) can be transmitted by blood transfusion. We determined the prevalence of T. gondii infection in healthy blood donors in Hermosillo city, Mexico, and the association of infection with T. gondii with the sociodemographic, clinical, and behavioral characteristics of blood donors. Four hundre...

journal_title：BioMed research international

authors： Alvarado-Esquivel C,Rascón-Careaga A,Hernández-Tinoco J,Corella-Madueño MA,Sánchez-Anguiano LF,Aldana-Madrid ML,Velasquez-Vega E,Quizán-Plata T,Navarro-Henze JL,Badell-Luzardo JA,Gastélum-Cano JM,Liesenfeld O

更新日期：2016-01-01 00:00:00

abstract：Objective:Cognitive impairment is considered to be an important complication of spinal cord injury (SCI), but its underlying mechanism remains unclear. The purpose of this study is to explore whether serum CCL21 can be used as a potential biomarker of cognitive impairment in SCI. Methods:In Neck-Shoulder and Lumbocrur...

journal_title：BioMed research international

authors： Chen Y,Liang L,Cao S,Hou G,Zhang Q,Ma H,Shi B

更新日期：2020-12-09 00:00:00

abstract：:Saponins are a group of naturally occurring plant glycosides with the features of their strong foam-forming properties and multibiological effects such as antitumor activity. Though Misaponin B, one of the triterpenoid saponins from Madhuca longifolia, is known to have spermicidal and antioxidant activity, the other b...

journal_title：BioMed research international

authors： Won G,Jung JH,Sohn EJ,Park JE,Kim H,Lee HJ,Shim BS,Kim SH

更新日期：2020-02-07 00:00:00

abstract：:Oyster mushroom Pleurotus florida was cultivated on different combinations of wheat straw (WS) as basal substrate and oyster shell powder (OSP) supplement. The OSP supplementation considerably responded to different cultivation phases. The mycelium grew fast and showed rapid growth rate (8.91 mmd(-1)) in WS + OSP (97 ...

journal_title：BioMed research international

authors： Naraian R,Narayan OP,Srivastava J

更新日期：2014-01-01 00:00:00

abstract：:Cumulative evidence has indicated that there is an important role for adult hippocampal neurogenesis in cognitive function. With the increasing prevalence of cognitive decline associated with neurodegenerative diseases among the ageing population, physical exercise, a potent enhancer of adult hippocampal neurogenesis,...

journal_title：BioMed research international

authors： Yau SY,Gil-Mohapel J,Christie BR,So KF

更新日期：2014-01-01 00:00:00

abstract：:Spinal cord stimulation has been utilized for decades in the treatment of numerous conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer pain, and others. The placement of the stimulating electrode array was originally subdural but, to minimize surgical complexity and reduce the risk...

journal_title：BioMed research international

authors： Gibson-Corley KN,Flouty O,Oya H,Gillies GT,Howard MA

更新日期：2014-01-01 00:00:00

abstract：:The purpose of this study was to assess the impact of 3 months of aromatase inhibition together with progestin add-back on ovarian endometrioma size. This prospective cohort study was performed at University Medical Center (UC San Diego). Women trying to conceive were excluded. After informed consent, all women were t...

journal_title：BioMed research international

authors： Agarwal SK,Foster WG

更新日期：2015-01-01 00:00:00

abstract：:Human dental pulp stem cells (DPSCs) hold great promise in bone regeneration. However, the exact mechanism of osteogenic differentiation of DPSCs remains unknown, especially the role of exosomes played in. The DPSCs were cultured and received osteogenic induction; then, exosomes from osteogenic-induced DPSCs (OI-DPSC-...

journal_title：BioMed research international

authors： Xie L,Guan Z,Zhang M,Lyu S,Thuaksuban N,Kamolmattayakul S,Nuntanaranont T

更新日期：2020-09-28 00:00:00

abstract：Introduction:The sources of Reactive Oxidative Species (ROS) in the organism are the respiratory processes occurring in cells catalyzed by different enzymes. Operation of ROS is balanced by antioxidants, the compounds; although present in low concentrations, they significantly inhibit the degree of oxidation of particu...

journal_title：BioMed research international

authors： Kuciel-Lewandowska J,Gnus J,Pawlik-Sobecka L,Płaczkowska S,Kokot I,Kasperczak M,Paprocka-Borowicz M

更新日期：2018-01-02 00:00:00

abstract：:Bovine pericardium is used for heart valve leaflet replacement where the strength and thinness are critical properties. Pericardium from neonatal animals (4-7 days old) is advantageously thinner and is considered as an alternative to that from adult animals. Here, the structures of adult and neonatal bovine pericardiu...

journal_title：BioMed research international

authors： Sizeland KH,Wells HC,Higgins J,Cunanan CM,Kirby N,Hawley A,Mudie ST,Haverkamp RG

更新日期：2014-01-01 00:00:00

abstract：:Persistent catecholamine-resistant shock in children causes severe morbidity and mortality. We aimed to analyze the association between hemodynamics and serum lactate at different time points and 28-day mortality in children with persistent catecholamine-resistant shock. Methods. Twenty-six children with persistent ca...

journal_title：BioMed research international

authors： Lee EP,Chu SC,Hsia SH,Chen KF,Chan OW,Lin CY,Su YT,Lin JJ,Wu HP

更新日期：2020-06-19 00:00:00

abstract：:Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...

journal_title：BioMed research international

authors： Sitzia C,Farini A,Colleoni F,Fortunato F,Razini P,Erratico S,Tavelli A,Fabrizi F,Belicchi M,Meregalli M,Comi G,Torrente Y

更新日期：2015-01-01 00:00:00

abstract：:Compressive sensing (CS) offers compression of data below the Nyquist rate, making it an attractive solution in the field of medical imaging, and has been extensively used for ultrasound (US) compression and sparse recovery. In practice, CS offers a reduction in data sensing, transmission, and storage. Compressive sen...

journal_title：BioMed research international

authors： Yousufi M,Amir M,Javed U,Tayyib M,Abdullah S,Ullah H,Qureshi IM,Alimgeer KS,Akram MW,Khan KB

更新日期：2019-11-15 00:00:00

abstract：:With the development of nanotechnology, nanocarriers have been increasingly used for curative drug/gene delivery. Various nanocarriers are being introduced and assessed, such as polymer nanoparticles, liposomes, and micelles. As a novel theranostic system, nanocarriers hold great promise for ultrasound molecular imagi...

journal_title：BioMed research international

authors： Zhou QL,Chen ZY,Wang YX,Yang F,Lin Y,Liao YY

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:To investigate whether P. acnes could induce disc degeneration and Modic changes when inoculated into the discs of rabbits. METHOD:A wild-type strain of P. acnes isolated from a patient associated with Modic change and disc degeneration was inoculated into the intervertebral discs of rabbits. Meanwhile, S. aur...

journal_title：BioMed research international

authors： Chen Z,Zheng Y,Yuan Y,Jiao Y,Xiao J,Zhou Z,Cao P

更新日期：2016-01-01 00:00:00

abstract：Background:Waldenström macroglobulinemia (WM) is a rare, indolent B-cell lymphoma. Clinically, chromosome 6q deletion (6q del) including loss of the B lymphocyte-induced maturation protein 1 gene (BLIMP-1) is reported to be associated with poor prognosis. However, it remains unclear how the underlying biological mechan...

journal_title：BioMed research international

authors： Sekiguchi N,Nomoto J,Nagata A,Kiyota M,Fukuda I,Yamada K,Takezako N,Kobayashi Y

更新日期：2018-10-04 00:00:00

abstract：:Myostatin, a TGF-β family member, is associated with inhibition of muscle growth and differentiation and might interact with the IGF-1 signaling pathway. Since IGF-1 is secreted at a bioactive level by adipose tissue-derived mesenchymal stem cells (ASCs), these cells (ASCs) provide a therapeutic option for Duchenne Mu...

journal_title：BioMed research international

authors： Gehmert S,Wenzel C,Loibl M,Brockhoff G,Huber M,Krutsch W,Nerlich M,Gosau M,Klein S,Schreml S,Prantl L,Gehmert S

更新日期：2014-01-01 00:00:00

abstract：:Sepsis is a severe and progressive disease characterized by systemic inflammatory response syndrome (SIRS). CD40 serves as a vital link between immune response and inflammation. This study was designed to investigate the potential association between a functional single-nucleotide polymorphism (SNP) of CD40 (rs1883832...

journal_title：BioMed research international

authors： Liu ZL,Hu J,Xiao XF,Peng Y,Zhao SP,Xiao XZ,Yang MS

更新日期：2018-03-26 00:00:00

abstract：:In renal cell carcinoma, chromophobe renal cell carcinoma (ChRCC) is a distinct subtype, whose clinical manifestations often lack specificity, and the molecular mechanisms of ChRCC tumorigenesis remain generally vague. The target of this study was to discover novel biomarkers involved in ChRCC by integrated bioinforma...

journal_title：BioMed research international

authors： Zhang W,Xu Y,Zhang J,Wu J

更新日期：2020-02-07 00:00:00