Abstract:
:Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive "one-stop-shop" diagnostic test that can provide both anatomical significance and functional significance of stenotic lesions would be beneficial in the diagnosis and management of CAD. Recently, with the introduction of novel techniques, such as myocardial CT perfusion, CT-derived fractional flow reserve (FFRCT), and transluminal attenuation gradient (TAG), CCTA has emerged as a noninvasive method for the assessment of both anatomy of coronary lesions and its physiological consequences during a single study. This review provides an overview of the current status of new CT techniques for the physiologic assessments of CAD.
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Xu L,Sun Z,Fan Zdoi
10.1155/2015/435737subject
Has Abstractpub_date
2015-01-01 00:00:00pages
435737eissn
2314-6133issn
2314-6141journal_volume
2015pub_type
杂志文章,评审abstract::Within-litter birth weight variation in multiparous animals has become a big issue due to high incidence of low birth weight neonates, which gives rise to high preweaning mortality and morbidity. Foetus with various birth weights is the outcome of diverse embryos competence which is affected by oocyte quality. Glucosa...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1630890
更新日期:2020-01-08 00:00:00
abstract::A metabolic disorder is considered one of the hallmarks of cancer. Multiple differentially expressed metabolic genes have been identified in colon cancer (CC), and their biological functions and prognostic values have been well explored. The purpose of the present study was to establish a metabolic signature to optimi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/4845360
更新日期:2020-11-17 00:00:00
abstract::[This corrects the article DOI: 10.1155/2017/8193821.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
doi:10.1155/2017/6418529
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:We investigated the integron types and their relation with antibiotic resistance among A. baumannii isolates collected from intensive care unit patients, Babol, north of Iran. METHODS:In this cross-sectional study, a total of 73 bronchoalveolar lavage samples were obtained from patients in ICU. Susceptibili...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/7157923
更新日期:2017-01-01 00:00:00
abstract::Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/140327
更新日期:2013-01-01 00:00:00
abstract::Toonaciliatin K is a natural limonoid purified from the Toona ciliata Roem. var. ciliata (Meliaceae). This study is to reveal the inflammatory suppression effect of toonaciliatin K and further the intrinsic mechanism. Firstly, anti-inflammatory effect of toonaciliatin K was evaluated in lipopolysaccharide- (LPS-) indu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9436280
更新日期:2017-01-01 00:00:00
abstract::Mucosal melanoma is a rare disease, which differs from its cutaneous counterpart genetically and for its clinical behaviour. Moreover this is a heterogeneous disease based on the tissue of origin. As CT7 and CT10 are highly expressed in cutaneous melanoma and are immunogenic in this disease, we analysed their expressi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/432479
更新日期:2015-01-01 00:00:00
abstract:Background:The aims of this study were to explore the characteristics of left ventricular (LV) functional changes in subjects with or without acute mountain sickness (AMS) and their associations with AMS incidence. Methods:A total of 589 healthy men were enrolled and took a trip from Chengdu (500 m, above sea level (a...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6028747
更新日期:2020-11-10 00:00:00
abstract::The early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI) is very important for treatment research and patient care purposes. Few biomarkers are currently considered in clinical settings, and their use is still optional. The objective of this work was to determine whether multimodal and nonpr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/961314
更新日期:2015-01-01 00:00:00
abstract::A Mycobacterium bovis knockout in p27-p55 operon was tested as an antituberculosis experimental vaccine in animal models. The mutant MbΔp27-p55 was significantly more attenuated in nude mice than its parental strain but more virulent than BCG Pasteur. Challenge experiments in mice and guinea pigs using M. bovis or M. ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/951978
更新日期:2014-01-01 00:00:00
abstract:Background:Musculoskeletal disorders (MSDs) are considered one of the most common health issues in working population and have a high social and economic impact. This study is aimed at determining the MSD patterns and associated risk factors among higher education academicians in Saudi Arabia. Methods:A cross-sectiona...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8930968
更新日期:2020-08-15 00:00:00
abstract::Tsetse flies (Glossina spp.) are the primary vectors of trypanosomes, which can cause human and animal African trypanosomiasis in Sub-Saharan African countries. The objective of this study was to explore the genome of Glossina morsitans morsitans for evidence of horizontal gene transfer (HGT) from microorganisms. We e...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3164624
更新日期:2016-01-01 00:00:00
abstract::Trichoderma spp. are important biocontrol filamentous fungi, which are widely used for their adaptability, broad antimicrobial spectrum, and various antagonistic mechanisms. In our previous studies, we cloned thga1 gene encoding GαI protein from Trichoderma harzianum Th-33. Its knockout mutant showed that the growth r...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/8329513
更新日期:2016-01-01 00:00:00
abstract::The effect of crocetin (C20H24O4) on methylcholanthrene- (MCA-) induced uterine cervical cancer in mice was studied in this paper. After the mice were treated orally with crocetin, maleic dialdehyde (MDA), polymorphonuclear cells (PMN), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were examined by ELISA...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/829513
更新日期:2015-01-01 00:00:00
abstract::Renal inflammation can result in renal injury. Uric acid (UA) is the final product of purine metabolism in humans and because of the lack of urate oxidase, UA may accumulate in tissues, including kidney, causing inflammation. Galangin was isolated from a traditional Chinese medicine plant and possesses several benefic...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/3018357
更新日期:2019-05-26 00:00:00
abstract:Background and Aims:The NF-κB pathway has been implicated in the genetic aetiology of psoriatic disease. However, since most patients with arthritis have psoriasis, discerning the genetic contributions to both aspects of psoriatic disease is not easy. Our aim was to study the association of common polymorphisms in gene...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/1030256
更新日期:2019-11-11 00:00:00
abstract::It is challenging and inspiring for us to achieve high spatiotemporal resolutions in dynamic cardiac magnetic resonance imaging (MRI). In this paper, we introduce two novel models and algorithms to reconstruct dynamic cardiac MRI data from under-sampled k - t space data. In contrast to classical low-rank and sparse mo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/169317
更新日期:2015-01-01 00:00:00
abstract:Background:The aim of this study was to assess changes in skin microbiota of wrestlers during training sessions and to determine the sensitivity of hemolytic bacterial isolates to antiseptics. Methods:The main skin bacterial isolates obtained from the skin of 15 wrestlers were identified by cultivation method, with th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/9843781
更新日期:2019-01-10 00:00:00
abstract::Ultrasonography has been widely employed to estimate the morphological changes of muscle during contraction. To further investigate the motion pattern of quadriceps during isometric knee extensions, we studied the relative motion pattern between femur and quadriceps under ultrasonography. An interesting observation is...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/6385315
更新日期:2018-03-18 00:00:00
abstract::During vertebrate development, the lung inaugurates as an endodermal bud from the primitive foregut. Dichotomous subdivision of the bud results in arborizing airways that form the prospective gas exchanging chambers, where a thin blood-gas barrier (BGB) is established. In the mammalian lung, this proceeds through conv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/101597
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Novel prognostic markers are needed so newly diagnosed breast cancer patients do not undergo any unnecessary therapy. Various microarray gene expression datasets based studies have generated gene signatures to predict the prognosis outcomes, while ignoring the large amount of information contained in establi...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/459203
更新日期:2014-01-01 00:00:00
abstract::With the recent advancement in the field of ocular therapy, drug delivery approaches have been elevated to a new concept in terms of nonionic surfactant vesicles (NSVs), that is, the ability to deliver the therapeutic agent to a patient in a staggered profile. However the major drawbacks of the conventional drug deliv...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/263604
更新日期:2014-01-01 00:00:00
abstract::Lycium barbarum is a famous plant in the traditional Chinese medicine. The plant is known to have health-promoting bioactive components. The properties of Lycium barbarum berries cultivated in Umbria (Italy) and their effect on human hepatocellular carcinoma cells (HepG2) have been investigated in this work. The obtai...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/7529521
更新日期:2016-01-01 00:00:00
abstract::Amyotrophic lateral sclerosis (ALS) is a fatal condition primarily characterized by the selective loss of upper and lower motor neurons. At present, the diagnosis and monitoring of ALS is based on clinical examination, electrophysiological findings, medical history, and exclusion of confounding disorders. There is the...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/525097
更新日期:2014-01-01 00:00:00
abstract::[This corrects the article DOI: 10.1155/2015/587135.]. ...
journal_title:BioMed research international
pub_type: 已发布勘误
doi:10.1155/2016/3017536
更新日期:2016-01-01 00:00:00
abstract::Primary cilia are organelles protruding from cell surface into environment that function in regulating cell cycle and modulating cilia-related signal. Primary ciliogenesis and autophagy play important roles in tumorigenesis. However, the functions and interactions between primary cilia and autophagy in hepatocellular ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/5202750
更新日期:2019-10-02 00:00:00
abstract::New antimicrobial properties of products derived from Humulus lupulus L. such as antiadherent and antibiofilm activities were evaluated. The growth of gram-positive but not gram-negative bacteria was inhibited to different extents by these compounds. An extract of hop cones containing 51% xanthohumol was slightly less...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/101089
更新日期:2013-01-01 00:00:00
abstract::Neuroendocrine tumors (NETs) are tumors originated from neuroendocrine cells in the body. The localization and the detection of the extent of NETs are important for diagnosis and treatment, which should be individualized according to the tumor type, burden, and symptoms. Molecular imaging of NETs with high sensitivity...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2013/102819
更新日期:2013-01-01 00:00:00
abstract::Many topical agents are available for treating the acute phase of acne; however, few agents have been proven beneficial during the maintenance phase. Objective. To evaluate the efficacy and safety of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid during the maintenance phase of ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/2857812
更新日期:2020-10-16 00:00:00
abstract:BACKGROUND:Noninvasive tools to diagnose nonalcoholic fatty liver disease (NAFLD), including transient elastography (TE) and enhanced liver fibrosis panel (ELF), have only been evaluated in children with biopsy-proven NAFLD. We evaluated the prevalence of ELF and TE abnormalities in obese children without clinical live...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/457473
更新日期:2015-01-01 00:00:00